Asymmetric synthesis of (1R, 2S, 3R)-2-acetyl-4(5)-(1,2,3,4-tetrahydroxybutyl)imidazole-Science-Chemical Encyclopedia-lookchem

Asymmetric synthesis of (1R, 2S, 3R)-2-acetyl-4(5)-(1,2,3,4-tetrahydroxybutyl)imidazole
Add time:07/16/2019 Source:sciencedirect.com

A method for preparing the biologically active compound (1R, 2S, 3R)-2-acetyl-4(5)-(1,2,3,4-tetrahydroxybutyl)imidazole1 using a palladium (0) catalysed coupling of 1-ethoxymethyl-4-iodoimidazole 2 to the functionalised vinylstannane 3 and the Sharpless catalytic asymmetric dihydroxylation is reported.

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