Add time:09/30/2019 Source:infona.pl
The direct sulfonamidation of primary and secondary benzylic alcohols catalyzed by a 2,3,4,5‐tetrafluorophenylboronic acid/oxalic acid co‐catalytic system was examined. The reaction proceeds under mild conditions with readily available starting materials and has been shown to be gram‐scalable without significant decrease of yield. Both primary and secondary benzylic alcohols were evaluated and afforded the desired sulfonamide products with good to excellent yields.
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