Add time:07/19/2019         Source:sciencedirect.com

Nitrile oxides 2 reacted with 3-diethylamino 4(4 methoxyphenyl)-isothiazole 1,1 dioxide (1) affording through a highly regioselective 1,3-dipolar cycloaddition reaction isothiazolo[5,4-d]isoxazoline 4,4 dioxides 3. Reduction of 3 afforded a mixture of the E and Z forms of the corresponding 5-(amino-aryl methylene]-dihydro-isothiazole 1,1-dioxides 4/5 which were transformed into 5-acyl-dihydro-isothiazole 1,1dioxides 6 and the corresponding dehydrated products 7. Compound 3f was easily transformed into 5-cyanoisothiazole 1,1-dioxide 11

We also recommend Trading Suppliers and Manufacturers of 2-amino-4-(2-chlorophenyl)-7-(diethylamino)-4H-chromene-3-carbonitrile (cas 371950-53-7). Pls Click Website Link as below: cas 371950-53-7 suppliers