Add time:09/29/2019 Source:infona.pl
Acremolin (1), a novel modified base, was isolated from the culture broth of the marine fungus Acremonium strictum. Based on combined spectroscopic analyses, the structure of this compound was that of a methyl guanine base containing an isoprene unit. In addition, the presence of a 1H-Azirine (cas 157-17-5) moiety is unprecedented among natural products. This compound exhibited weak cytotoxicity against an A549 cell line.
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