Add time:07/19/2019         Source:sciencedirect.com

A series of novel tetrahydropyrimidines was synthesized and examined for M1 muscarinic receptor activity. 1,4,5,6-Tetrahydro-5-methoxycarbonyl-pyrimidine hydrobromide (1a; CDD-0034-C) displayed a high affinity for muscarinic receptors in rat brain and stimulated PI metabolism in rat hippocampus. Compound 1a ameliorated memory deficits associated with lesions of the septohippocampal cholinergic system in rats.

We also recommend Trading Suppliers and Manufacturers of 1,4,5,6-TETRAHYDROPYRIMIDINE (cas 1606-49-1). Pls Click Website Link as below: cas 1606-49-1 suppliers