A Practical Stereoselective Synthesis of both Enantiomers of Threo- and Erythro-β-Hydroxy Norvaline from (S)-Serine Derivatives-Science-Chemical Encyclopedia-lookchem

A Practical Stereoselective Synthesis of both Enantiomers of Threo- and Erythro-β-Hydroxy Norvaline from (S)-Serine Derivatives
Add time:07/18/2019 Source:sciencedirect.com

The four enantiopure diastereoisomers of β-hydroxy norvaline have been prepared from l-serine in moderate chemical yield. The method is based on the diastereoselective addition of different organometallics to easily accessible serinal derivatives.

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