FT-IR (4000-400 cm−1) and FIR (400-10 cm−1) spectra of α-modification of acid potassium iodate (α-KIO3·HIO3) were measured in the paraelectric (at 300-220 K) and ferroelectric (at 223-20 K) phases. FIR spectra of the ferroelectric phase were found to exhibit doublet structure of many bands wh...

Wet process phosphoric acid (WPA) manufacturing is mainly via the dihydrate process. Phosphogypsum is the by-product. The size distribution of phosphogypsum is a major factor for the economics of the process as it greatly affects filtration efficiency of the acid. The goal of this study is to en...

The fluoride uptake by various calcium phosphate minerals is reported. Hydroxyapatite (HA), octacalcium phosphate (OCP), and dicalcium phosphate dihydrate (DCPD) were individually exposed to fluoride, and they absorbed fluoride through fluorapatite formation. The fluorapatite formation was throu...

SummaryPotassium (K+) efflux across the plasma membrane is thought to be an essential mechanism for ATP-induced NLRP3 inflammasome activation, yet the identity of the efflux channel has remained elusive. Here we identified the two-pore domain K+ channel (K2P) TWIK2 as the K+ efflux channel trigg...

Silyl ethers can be removed under mild conditions by treatment with a mixture of potassium fluoride dihydrate and 18-crown-6 in DMF or THF at room temperature. Both acid and base-labile protecting groups are unaffected.

BackgroundThe authors conducted a laboratory study to determine the carious lesion remineralization and fluoridation potential of fluoride (F)- and calcium-containing toothpastes.

Methylhexamethylenetetramine fluoride dihydrate has been prepared by conventional methods. It is moderately soluble in polar aprotic solvents, and shows good thermal stability, enabling it to be dried. The reagent is capable of converting activated nitroaromatics to the corresponding fluoroaroma...

Dicalcium phosphate dihydrate (CaHPO4·2H2O, DCPD also known as brushite) is the major component of hard tissues like bone, teeth and a medicine for calcium supply. The effect of sodium fluoride and potassium fluoride on the crystallization of DCPD in sodium meta silicate gel has been studied at...

The large birefringence and small dispersion of potassium dithionate will enable phase-matched optical mixing processes to be performed in the visible and infra-red to 6 μm but the nonlinear coefficients are less than those of potassium dihydrogen phosphate.

With an increasing interest in using protons and light ions for radiation therapy there is a need for possibilities to simultaneously determine both absorbed dose (D) and linear energy transfer, LET, (LΔ). Potassium dithionate (K2S2O6) tablets were irradiated in a conventional 6 MV linear accel...

The structures of the free radicals formed by the irradiation of potassium dithionate (K2S2O6) with 60Co γ-rays and 14N7+ ions were investigated by EPR to further examine a recently proposed LET effect in this material. Two types of SO3− radical ions were identified in X-irradiated single cryst...

Reaction of the known cyclometallated platinum(II) complexes [PtMe(CˆN)(PPh2Me)], in which CˆN is either 2-phenylpyridinate (abbreviated as ppy-H), 1a, or benzo-h-quinolate (abbreviated as bhq-H), 1b, with excess allyl bromide, CH2=CH-CH2Br, in acetone gave the thermodynamic Pt(IV) product compl...

Dissociative electron attachment to PtBr2 in the gas phase was studied in the low electron energy range from zero up to 10 eV with an energy resolution of 150 meV. The experiments were carried out using a hemispherical electron monochromator coupled with a quadrupole mass spectrometer and pulse ...

Naphthalimide platinum(IV) antitumor complexes with potential dual DNA damage mechanism were designed, synthesized and evaluated for antitumor activities. The incorporation of DNA targeted naphthalimide group to the platinum(IV) system exerts much positive impacts on their antitumor efficacy. Th...

Tetracarboxylatoplatinum(IV) complexes are interesting representatives of potential anticancer active platinum(IV) drugs. Revealing higher kinetic inertness in comparison to their cytotoxic platinum(II) counterparts, they offer an opportunity to reduce toxic and deactivating side reactions. Plat...

AbstrctIncreasing evidences suggested that cisplatin can be involved in a tumor-specific immune response as an immunomodulator to improve antitumor immunity, but the designation and development are limited. Here, we report a series of novel Pt(IV) complexes derived from the conjugation of platin...

A series of complexes of the type [Pt(PL)(AL)(X)2]2+ (where PL = 1,10-phenanthroline, 5-methyl-1,10-phenanthroline or 5,6-dimethyl-1,10-phenanthroline; AL = 1S,2S-diaminocyclohexane and, X = Cl, Br or I) with anticancer potency, were synthesised in a one pot reaction using N-halogensuccinimide (...

Three biotinylated platinum(IV) complexes (1–3) were designed and synthesized. The resulting platinum(IV) complexes exhibited effective cytotoxicity against the tested cancer cell lines, especially complex 1, which was 2.0–9.6-fold more potent than cisplatin. These complexes were found to be r...

New platinum(IV) complexes containing N2S2 donor atoms were synthesized by the reactions of [Pt(p-MeC6H4)2(SMe2)2] and [PtCl2(DMSO)2] with 2,2′-dithiopyridine (dtp) in 1:1 M ratio. In these reactions, 2-mercaptopyridine (mpy) ligands were formed through the cleavage of the disulfide bond in 2,2...

A series of new 4-hydroxycoumarin platinum(IV) complexes were designed, synthesized and evaluated as antitumor agents. All the title compounds display moderate to effective antitumor activities toward the tested cell lines and two prominent compounds were screened out with activities comparable ...