A novel class of pyrrolidine–pyridinium based organocatalysts has been developed and demonstrated to efficiently catalyze the asymmetric Michael addition reactions of unmodified cyclohexanone to nitroalkenes in the ionic liquid BMImBF4 with up to 95% yield and nearly 100% ee. The catalytic syst...

Amine-catalyzed direct self Diels–Alder reactions of α,β-unsaturated ketones have been developed. (S)-1-(2-Pyrrolidinyl-methyl)pyrrolidine, l-proline and pyrrolidine catalyzed the reaction of α,β-unsaturated ketones to provide cyclohexanone derivatives with good yield (up to 80%) in a singl...

A new method for the determination of 2-[(dimethylamino)methyl]cyclohexanone (DAMC) in Tramadol (as active substance or active ingredient in pharmaceutical formulations) is described. The method is based on the derivatisation of 2-[(dimethylamino)methyl]cyclohexanone with 2,4-dinitrophenylhydraz...

A series of eleven new 5-arylazo-6-hydroxy-4-(4-methoxyphenyl)-3-cyano-2-pyridone dyes was synthesized and their absorption spectra were recorded in twenty solvents in the range 300–600 nm. Different solvent parameters, such as microscopic solvent polarity, ETN, relative permittivity, εr, refr...

Synthesis of a fluorinated benzamide neuroleptic, (S)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(3-fluoropropyl)-2,3-dimethoxybenzamide starting from 3-(3,4-dimethoxyphenyl)-1-propanol in 20–25% overall yield is reported. Radiosynthesis of (S)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(3[18F]fluoropropyl...

Density functional calculations at B3LYP/6-31G∗ level were presented for some derivatives of dihydrophenazine. In agreement with the experimental observations, both compounds 1 and 2 have been found to establish non-planar orientations in regard to their dihydrophenazine moiety. Both the non-pla...

A novel dicyanovinyl-functionalized N,N,N’,N’-tetraphenylbenzidine (TPD) derivative, N,N’-bis[4-(1,1-dicyanovinyl)phenyl]-N,N’-bis(4-fluorophenyl)benzidine and a novel triphenylamine-based derivative, 4,4′,4″-tris{[di(p-tolyl)amino]phenyl}triphenylamine were synthesized and employed as red...

In this paper, the thermally induced crystallization behavior of N,N,N′,N′-tetraphenylbenzidine (TPB) and N,N,N′,N′-tetra-p-tolylbenzidine (TTB) and their microstructure changes as well as π–π aggregation mode as film state were comprehensively studied. The influence of heating rate, anne...

A N,N,N',N'-tetraphenylbenzidine-bridged bis(2,2'-bipyridine) ligand and corresponding diruthenium complexes were synthesized and characterized. They show rich multistep redox processes due to the stepwise oxidations of the amine units and ruthenium components. Their absorption an...

Bismuth can be determined spectrophotometrically at 495 nm after its extraction as tetramethylenebis(triphenylphosphonium) tetraiodobismuthate(III) into dichloromethane. The carrier stream is 2 M sulphuric acid and the reagent stream contains 2% (w/v) potassium iodine and 0.4% (w/v) tetramethyle...

Chromium(VI) (0–5 μg) can be determined spectrophotometrically at 365 nm after flow-injection extraction into chloroform of the ion-associate, tetramethylenebis(triphenylphosphonium) dichromate. The carrier stream is distilled water and the reagent stream contains 1 M sulphuric acid and 0.5% (...

The optimization and spectral (IR, 1H and 13C NMR) analysis of the synthesized chalcone derivative (2E)-3-[4-(dimethylamino) phenyl]-1-(naphthalen-2-yl) prop-2-en-1-one was carried out using DFT B3LYP/6-311G (d,p) method and compared with experimental results. The GIAO method was used to calcula...

Five novel fluorescent azo disperse dyes were synthesized using different diazotized aromatic amines followed by coupling with 3-(1,3-benzothiazol-2-yl)naphthalen-2-ol. These dyes were characterized by FT-IR, 1H NMR and mass spectroscopy. These azo disperse dyes were applied on polyester and the...

In this paper, the synthesis of [sodium alginate/4-methyl-2-(naphthalen-2-yl)-N-propylpentanamide-functionalized ethoxy-silica] composite gel beads is described. The characterizations were carried out using Fourier Transform InfraRed, Scanning Electron Microscopy, point zero charge and water con...

The preparation of novel unsymmetrical, tridentate ligand, N-methyl-N-(naphthalen-2-ylmethyl)-2-(pyridin-2-yl) ethanamine (1), has been described. Ligand 1 reacts with Pd(OAc)2 to give the corresponding cyclometallated complex, which could not be isolated. The substitution reactions of the in-si...

Three novel molecules were designed and synthesized based on a known compound 9,10-di(naphthalen-2-yl)anthracene (MADN). To broaden the π-conjugated system, three units with different electronegativity were introduced and connected to the C-2 position of MADN by vinyl unit. The Suzuki reaction,...

Defect-mediated Z-scheme BiO2-x/Bi2O2.75 heterojunction photocatalysts without electron mediator was prepared via a simple low-temperature hydrothermal method. DFT proved that the existence of oxygen vacancies would affect the geometric and electronic structure of BiO2-x and Bi2O2.75, which play...

A novel visible-light response heterojunction photocatalytic catalyst was developed in this study. The fragmented O-g-C3N4 discontinuously coated on the surface of Fe-TiO2, which exhibited excellent photocatalytic activity, photocatalytic stability and long-term durability under visible light ir...

In catalytic double bond migration reaction, E-configuration olefins were normally generated as the dominant product because E-configuration was thermodynamically favored. However, Z-configuration products are sometimes desired in pharmaceutical chemistry owing to the structure-activity relation...

Background and aimsOxidative stress-induced endothelial dysfunction is considered to exert a vital role in the development of atherosclerotic coronary heart disease (CHD). NRF2 is a key transcriptional factor against oxidative stress through activation of multiple ARE-mediated genes. Z-Lig is de...