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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

2-Bromo-5-fluoroaniline Manufacturer/High quality/Best price/In stock

Cas:1003-99-2

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 2-Bromo-5-Fluoroaniline supplier in China

Cas:1003-99-2

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Hebei yanxi chemical co.,LTD.

Hebei Yanxi Chemical Co., Ltd. is a professional research, development and production of lead acetate benzene acetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low car

2-Bromo-5-fluoroaniline Manufacturer

Cas:1003-99-2

Min.Order:1 Metric Ton

FOB Price: $1.0 / 2.0

Type:Manufacturers

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Jinan Finer Chemical Co., Ltd

Product Description Product Name 2-Bromo-5-fluoroaniline CAS No. 1003-99-2 Appearance

2-Bromo-5-fluoroaniline

Cas:1003-99-2

Min.Order:10 Gram

FOB Price: $20.0 / 30.0

Type:Lab/Research institutions

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

2-Bromo-5-Fluoroaniline

Cas:1003-99-2

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2-Bromo-5-fluoroaniline

Cas:1003-99-2

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company engages in Sodium Tripolyphosphate (STPP) and Sodium Hexametabphosphate (SHMP) production; development of noble metal catalysts, synthesis of electronic chemical materials and general chemicals Imp&Exp trading business. The company

TIANFU-CHEM - 2-Bromo-5-fluoroaniline

Cas:1003-99-2

Min.Order:1 Kilogram

FOB Price: $1000.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

2-Bromo-5-fluoroaniline

Cas:1003-99-2

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Top Purity CAS 1003-99-2 with fast shipping

Cas:1003-99-2

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2-Bromo-5-fluoroaniline 1003-99-2

Cas:1003-99-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

2-Bromo-5-fluoroaniline 99%

Cas:1003-99-2

Min.Order:1 Kilogram

FOB Price: $84.0 / 99.0

Type:Trading Company

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2-Bromo-5-fluoroaniline

Cas:1003-99-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

2-Bromo-5-fluoroaniline

Cas:1003-99-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

2-Bromo-5-Fluoroaniline

Cas:1003-99-2

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

2-Bromo-5-fluoroaniline

Cas:1003-99-2

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2-Bromo-5-fluoroaniline

Cas:1003-99-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Xinhao Biotechnology Co., Ltd.

Our Strengths 1.Place of Origin China with Super quality by reasonable price. 2.Fast delivery by safe express way to all the country. 3.Has a number of highly qualified engineers and experts to provide guidance for reagents. 4.When you meet problems

Factory supply 2-Bromo-5-fluoroaniline with Good Price CAS NO.1003-99-2

Cas:1003-99-2

Min.Order:1 Kilogram

FOB Price: $10.0

Type:Trading Company

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providing h

Factory Supply 2-Bromo-5-fluoroaniline

Cas:1003-99-2

Min.Order:0

Negotiable

Type:Other

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

2-Bromo-5-fluoroaniline

Cas:1003-99-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

2-Bromo-5-fluoroaniline Basic information Product Name: 2-Bromo-5-fluoroaniline Synonyms: 2-BROMO-5-FLUOROBENZENAMINE;2-BROMO-5-FLUOROANILINE;2-Bromo-5-fluoro-phenylamine;2-Bromo-5-fluoroaniline 98%;2-Bromo-5-fluoroaniline98%;2-Bromo-5-fluoroaniline

2-Bromo-5-fluoroaniline

Cas:1003-99-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

2-Bromo-5-fluoroaniline

Cas:1003-99-2

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

1003-99-2 CAS NO.1003-99-2

Cas:1003-99-2

Min.Order:1 Metric Ton

FOB Price: $7.0 / 8.0

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

2-Bromo-5-fluoroaniline

Cas:1003-99-2

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

SAGECHEM LIMITED

SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in custom synthe

SAGECHEM/2-Bromo-5-fluoroaniline

Cas:1003-99-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, intermediat

2-Bromo-5-fluoroaniline

Cas:1003-99-2

Min.Order:1 Kilogram

FOB Price: $5.0 / 15.0

Type:Lab/Research institutions

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

2-bromo-5-fluoroaniline

Cas:1003-99-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

2-Bromo-5-fluoroaniline

Cas:1003-99-2

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Beijing Greenchem Technology Co.,Ltd. ( Panjin Greenchem Technology Co.Ltd .)

Capability on chemical synthesis1. Beijing High-Tech Enterprises2. Strong R&D Team3. 8 years of experiences in R & D of high-tech Catalyst;4. 5000 production techniques, 69 items of national patents, and 360 kinds of products on sales;5. The producti

2-Bromo-5-fluoroaniline

Cas:1003-99-2

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

2-Bromo-5-Fluoroaniline cas no. 1003-99-2 98%

Cas:1003-99-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

2-Bromo-5-fluoroaniline

Cas:1003-99-2

Min.Order:0

Negotiable

Type:Other

inquiry

Synthetic route

2-bromo-5-fluoronitrobenzene
446-09-3

2-bromo-5-fluoronitrobenzene

2-bromo-5-fluoroaniline
1003-99-2

2-bromo-5-fluoroaniline

Conditions
ConditionsYield
Stage #1: 2-bromo-5-fluoronitrobenzene With iron; acetic acid In ethanol at 20℃; for 2.08333h; Heating / reflux;
Stage #2: With sodium hydroxide In diethyl ether; water
100%
With tin(ll) chloride In ethanol at 50℃; for 2h; Reagent/catalyst; Temperature;100%
With iron; acetic acid In ethanol; water at 80 - 85℃; for 6h;98.9%
2-azido-1-bromo-5-fluorobenzene
909274-50-6

2-azido-1-bromo-5-fluorobenzene

2-bromo-5-fluoroaniline
1003-99-2

2-bromo-5-fluoroaniline

Conditions
ConditionsYield
With iron(III) oxide; hydrazine hydrate In water at 120℃; for 2.5h; Inert atmosphere;81%
2-nitro-4-fluoroaniline
364-78-3

2-nitro-4-fluoroaniline

2-bromo-5-fluoroaniline
1003-99-2

2-bromo-5-fluoroaniline

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: HCl; aq. NaNO2 / 0 °C
1.2: CuBr; HCl / 0 - 60 °C
2.1: H2 / Raney Ni
View Scheme
meta-fluoroaniline
372-19-0

meta-fluoroaniline

A

2-bromo-5-fluoroaniline
1003-99-2

2-bromo-5-fluoroaniline

B

3-fluoro-4-bromophenylamine
656-65-5

3-fluoro-4-bromophenylamine

Conditions
ConditionsYield
With N-Bromosuccinimide In DCE at 20℃;A 11 %Chromat.
B 89 %Chromat.
1-Bromo-4-fluorobenzene
460-00-4

1-Bromo-4-fluorobenzene

2-bromo-5-fluoroaniline
1003-99-2

2-bromo-5-fluoroaniline

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sulfuric acid; nitric acid / water / 0.25 h / 0 °C
2: ammonium chloride; zinc / water / 0.5 h / 80 °C
View Scheme
meta-fluoroaniline
372-19-0

meta-fluoroaniline

2-bromo-5-fluoroaniline
1003-99-2

2-bromo-5-fluoroaniline

Conditions
ConditionsYield
With hydrogen bromide; dimethyl sulfoxide In ethyl acetate at 60℃; for 12h;
4-fluoroaniline
371-40-4

4-fluoroaniline

2-bromo-5-fluoroaniline
1003-99-2

2-bromo-5-fluoroaniline

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: toluene / 2 h / 5 - 25 °C / Large scale
2.1: sulfuric acid / dichloromethane / 1 h / 0 - 5 °C
2.2: 1 h / 5 - 10 °C
3.1: sulfuric acid / water / 14 h / 75 - 80 °C
3.2: 1 h / 0 - 5 °C
3.3: 2 h / 40 - 50 °C
4.1: iron; acetic acid / water; ethanol / 6 h / 80 - 85 °C
View Scheme
4'-fluoroacetanilide
351-83-7

4'-fluoroacetanilide

2-bromo-5-fluoroaniline
1003-99-2

2-bromo-5-fluoroaniline

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: sulfuric acid / dichloromethane / 1 h / 0 - 5 °C
1.2: 1 h / 5 - 10 °C
2.1: sulfuric acid / water / 14 h / 75 - 80 °C
2.2: 1 h / 0 - 5 °C
2.3: 2 h / 40 - 50 °C
3.1: iron; acetic acid / water; ethanol / 6 h / 80 - 85 °C
View Scheme
cis,trans-2,5-dimethoxytetrahydrofuran
696-59-3

cis,trans-2,5-dimethoxytetrahydrofuran

2-bromo-5-fluoroaniline
1003-99-2

2-bromo-5-fluoroaniline

1-(2-bromo-5-fluorophenyl)-1H-pyrrole
1254221-18-5

1-(2-bromo-5-fluorophenyl)-1H-pyrrole

Conditions
ConditionsYield
With water; acetic acid In 1,2-dichloro-ethane at 80℃; Paal-Knorr pyrrole synthesis; Inert atmosphere;100%
With acetic acid for 1h; Reflux;
2-bromo-5-fluoroaniline
1003-99-2

2-bromo-5-fluoroaniline

pivaloyl chloride
3282-30-2

pivaloyl chloride

N-(2-bromo-5-fluorophenyl)pivalamide
885609-84-7

N-(2-bromo-5-fluorophenyl)pivalamide

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 2h;98%
With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 2h;98%
With triethylamine In dichloromethane at 0 - 20℃; for 3h;92%
With triethylamine In dichloromethane at 0 - 30℃;
With triethylamine In dichloromethane at 0 - 20℃;
2-iodobiphenyl
2113-51-1

2-iodobiphenyl

2-bromo-5-fluoroaniline
1003-99-2

2-bromo-5-fluoroaniline

7-fluoro-9H-tribenzo[b,d,f]azepine

7-fluoro-9H-tribenzo[b,d,f]azepine

Conditions
ConditionsYield
With palladium diacetate; caesium carbonate; tris-(o-tolyl)phosphine In N,N-dimethyl-formamide at 120℃; for 36h; Schlenk technique; Inert atmosphere;98%
2-bromo-5-fluoroaniline
1003-99-2

2-bromo-5-fluoroaniline

4-fluoroboronic acid
1765-93-1

4-fluoroboronic acid

4,4'-difluoro-[1,1'-biphenyl]-2-amine
2367-21-7

4,4'-difluoro-[1,1'-biphenyl]-2-amine

Conditions
ConditionsYield
With potassium phosphate; tetrakis(triphenylphosphine) palladium(0) In ethanol; water; toluene at 96℃; for 24h; Inert atmosphere;97%
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In ethanol; water; toluene at 100℃; for 24h;
2-bromo-5-fluoroaniline
1003-99-2

2-bromo-5-fluoroaniline

benzoyl chloride
98-88-4

benzoyl chloride

N-(2-bromo-5-fluorophenyl)benzamide
1629-17-0

N-(2-bromo-5-fluorophenyl)benzamide

Conditions
ConditionsYield
In tetrahydrofuran at 20℃; for 24h;96%
With triethylamine In dichloromethane at 20℃; for 3h;
2-bromo-5-fluoroaniline
1003-99-2

2-bromo-5-fluoroaniline

2-azido-1-bromo-5-fluorobenzene
909274-50-6

2-azido-1-bromo-5-fluorobenzene

Conditions
ConditionsYield
Stage #1: 2-bromo-5-fluoroaniline With hydrogenchloride; sodium nitrite In water at 0 - 5℃; for 1.5h;
Stage #2: With sodium azide; sodium acetate In water at 0 - 5℃; for 1h;
96%
Stage #1: 2-bromo-5-fluoroaniline With hydrogenchloride; sodium nitrite In water at 0 - 5℃; for 1.5h;
Stage #2: With sodium azide; sodium acetate In water at 0 - 5℃; for 1h;
96%
Stage #1: 2-bromo-5-fluoroaniline With hydrogenchloride; sodium nitrite In water at 0 - 5℃; for 1.5h;
Stage #2: With sodium azide; sodium acetate In water at 0 - 5℃; for 1h;
96%
With tert.-butylnitrite; trimethylsilylazide In acetonitrile at 0 - 20℃; for 0.5h; Inert atmosphere;53%
2-bromo-5-fluoroaniline
1003-99-2

2-bromo-5-fluoroaniline

acetic anhydride
108-24-7

acetic anhydride

N-(2-bromo-5-fluoro-phenyl)acetamide
1009-06-9

N-(2-bromo-5-fluoro-phenyl)acetamide

Conditions
ConditionsYield
In dichloromethane Inert atmosphere; Reflux;96%
at 10 - 20℃; for 3h;90%
2-bromo-5-fluoroaniline
1003-99-2

2-bromo-5-fluoroaniline

benzyl chloroformate
501-53-1

benzyl chloroformate

2-bromo-5-fluorobenzyloxycarbonylaniline
1643796-25-1

2-bromo-5-fluorobenzyloxycarbonylaniline

Conditions
ConditionsYield
With sodium hydrogencarbonate In 1,2-dichloro-ethane at 0 - 10℃; for 1h;95.6%
With pyridine In ethyl acetate at 20℃; for 2h;85%
2-bromo-5-fluoroaniline
1003-99-2

2-bromo-5-fluoroaniline

diethyl 2-ethoxymethylenemalonate
87-13-8

diethyl 2-ethoxymethylenemalonate

diethyl {[(2-bromo-5-fluorophenyl)amino]methylene}malonate
655236-27-4

diethyl {[(2-bromo-5-fluorophenyl)amino]methylene}malonate

Conditions
ConditionsYield
for 16h; Heating;95%
at 120℃; for 2h; Neat (no solvent);84%
at 100℃; for 2h;
trans-Crotonaldehyde
123-73-9

trans-Crotonaldehyde

2-bromo-5-fluoroaniline
1003-99-2

2-bromo-5-fluoroaniline

8-bromo-5-fluoro-2-methylquinoline
904694-59-3

8-bromo-5-fluoro-2-methylquinoline

Conditions
ConditionsYield
Stage #1: trans-Crotonaldehyde; 2-bromo-5-fluoroaniline With hydrogenchloride In water at 100℃; for 1h; Heating / reflux;
Stage #2: With zinc(II) chloride In water at 0℃; for 0.5h;
Stage #3: With ammonia In water pH=8.0;
95%
Stage #1: 2-bromo-5-fluoroaniline With hydrogenchloride In water; toluene for 0.5h; Reflux;
Stage #2: trans-Crotonaldehyde In water; toluene for 18h; Reflux;
40%
2-bromo-5-fluoroaniline
1003-99-2

2-bromo-5-fluoroaniline

4‑ntro‑N’‑(1‑phenylethylidene)benzenesulfonohydrazide

4‑ntro‑N’‑(1‑phenylethylidene)benzenesulfonohydrazide

5-fluoro-2-(1-phenylvinyl)aniline

5-fluoro-2-(1-phenylvinyl)aniline

Conditions
ConditionsYield
With di-tert-butyl(methyl)phosphonium tetrafluoroborate salt; palladium diacetate; potassium carbonate In N,N-dimethyl acetamide at 110℃; Inert atmosphere;95%
2-bromo-5-fluoroaniline
1003-99-2

2-bromo-5-fluoroaniline

trimethylsilylacetylene
1066-54-2

trimethylsilylacetylene

5-fluoro-2-((trimethylsilyl)ethynyl)aniline

5-fluoro-2-((trimethylsilyl)ethynyl)aniline

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine In toluene at 20℃; for 24h; Sonogashira Cross-Coupling; Inert atmosphere;95%
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine at 20℃; Inert atmosphere; Sealed tube;
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

2-bromo-5-fluoroaniline
1003-99-2

2-bromo-5-fluoroaniline

tert-butyl N-(2-bromo-5-fluorophenyl)carbamate
861931-75-1

tert-butyl N-(2-bromo-5-fluorophenyl)carbamate

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 10℃; for 10h;94.2%
Stage #1: di-tert-butyl dicarbonate; 2-bromo-5-fluoroaniline With dmap In tetrahydrofuran for 3h; Reflux; Inert atmosphere;
Stage #2: With potassium carbonate In methanol for 3h; Reflux; Inert atmosphere;
76%
75%
1-(2,4-difluorophenyl)pentane-1,4-dione
908292-39-7

1-(2,4-difluorophenyl)pentane-1,4-dione

2-bromo-5-fluoroaniline
1003-99-2

2-bromo-5-fluoroaniline

1-(2-bromo-5-fluorophenyl)-2-(2,4-difluorophenyl)-5-methyl-1H-pyrrole
1445874-22-5

1-(2-bromo-5-fluorophenyl)-2-(2,4-difluorophenyl)-5-methyl-1H-pyrrole

Conditions
ConditionsYield
With gadolinium(III) trifluoromethanesulfonate In acetonitrile at 30℃; for 0.5h; Paal-Knorr Pyrrole Synthesis;94%
2-bromo-5-fluoroaniline
1003-99-2

2-bromo-5-fluoroaniline

N,N-dimethyl-formamide
68-12-2, 33513-42-7

N,N-dimethyl-formamide

N'-(2-bromo-5-fluorophenyl)-N,N-dimethylformimidamide

N'-(2-bromo-5-fluorophenyl)-N,N-dimethylformimidamide

Conditions
ConditionsYield
Stage #1: N,N-dimethyl-formamide With pyridine-2-sulfonyl chloride for 0.0833333h;
Stage #2: 2-bromo-5-fluoroaniline at 20℃;
93.9%
2-bromo-5-fluoroaniline
1003-99-2

2-bromo-5-fluoroaniline

potassium phtalimide
1074-82-4

potassium phtalimide

2-bromo-5-fluorophthalimidoaniline

2-bromo-5-fluorophthalimidoaniline

Conditions
ConditionsYield
With sodium hydroxide In tetrahydrofuran at 0 - 40℃; for 6h;93.8%
2-bromo-5-fluoroaniline
1003-99-2

2-bromo-5-fluoroaniline

p-toluenesulfonyl chloride
98-59-9

p-toluenesulfonyl chloride

N-(2-bromo-5-fluorophenyl)-4-methylbenzenesulfonamide

N-(2-bromo-5-fluorophenyl)-4-methylbenzenesulfonamide

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 10℃; for 0.5h;93.5%
With pyridine In tetrahydrofuran at 40℃;
With pyridine for 24h;8.78 g
Stage #1: 2-bromo-5-fluoroaniline With pyridine In ethyl acetate for 0.166667h;
Stage #2: p-toluenesulfonyl chloride In ethyl acetate
Stage #1: 2-bromo-5-fluoroaniline With pyridine In dichloromethane at 0℃; for 0.166667h; Inert atmosphere;
Stage #2: p-toluenesulfonyl chloride at 20℃; Inert atmosphere;
2-bromo-5-fluoroaniline
1003-99-2

2-bromo-5-fluoroaniline

isobutyryl chloride
79-30-1

isobutyryl chloride

2-bromo-5-fluoroisobutyranilide

2-bromo-5-fluoroisobutyranilide

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 10℃; for 0.5h;93.5%
2-bromo-5-fluoroaniline
1003-99-2

2-bromo-5-fluoroaniline

acetyl chloride
75-36-5

acetyl chloride

N-(2-bromo-5-fluoro-phenyl)acetamide
1009-06-9

N-(2-bromo-5-fluoro-phenyl)acetamide

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 10℃; for 0.5h;93.2%
With N-ethyl-N,N-diisopropylamine In dichloromethane at 0 - 20℃; for 16h; Inert atmosphere;3 g
Acetyl bromide
506-96-7

Acetyl bromide

2-bromo-5-fluoroaniline
1003-99-2

2-bromo-5-fluoroaniline

N-(2-bromo-5-fluoro-phenyl)acetamide
1009-06-9

N-(2-bromo-5-fluoro-phenyl)acetamide

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 10℃; for 0.5h;92.9%
2-bromo-5-fluoroaniline
1003-99-2

2-bromo-5-fluoroaniline

3-methyl-4-nitro-benzoyl chloride
35675-46-8

3-methyl-4-nitro-benzoyl chloride

N-(2-bromo-5-fluorophenyl)-3-methyl-4-nitrobenzamide
343975-60-0

N-(2-bromo-5-fluorophenyl)-3-methyl-4-nitrobenzamide

Conditions
ConditionsYield
With pyridine for 1h; Heating;92%
With pyridine for 2h; Reflux;84%

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