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Anhui Dexinjia Biopharm Co., Ltd

As a leading and professional manufacturer of APIs and API intermediates in China,Anhui Dexinjia Biopharm Co., Ltd founded in 2006, Except for the R&D center, our company has built a close cooperation relation with Chinese Academy of Sciences,

N-BOC-4-Hydroxypiperidine,98%

Cas:109384-19-2

Min.Order:1 Kilogram

FOB Price: $150.0 / 250.0

Type:Manufacturers

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Kono Chem Co.,Ltd

109384-19-2 Molecular Formula C10H19NO3 Molecular Weight 201.26 N-BOC-4-Hydroxypiperidine Molecular Formula C10H19NO3 Molecular Weight 201.26 CAS Registry Number 109384-19-2 Name

CAS:109384-19-2 N-BOC-4-Hydroxypiperidine

Cas:109384-19-2

Min.Order:1 Kilogram

Negotiable

Type:Other

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off white powder Storage:Sealed, dry, microtherm , avoid light and smell Package:According to the demand of customer Application:Pharmaceutical intermediates Transportation:by air or by sea Port:shanghai

1-Boc-4-piperidinol

Cas:109384-19-2

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply N-BOC-4-Hydroxypiperidine

Cas:109384-19-2

Min.Order:1

Negotiable

Type:Other

inquiry

ANQING CHICO PHARMACEUTICAL CO.,LTD.

High quality. Factory supply. In stock. Best price.1.Quick response within 24 hours;2.Best quality in your requirement;?3.We pay more attention on delivery time, and usually ship on time;4.Under the premise of safety and effectiveness, we can produce

N-BOC-4-Hydroxypiperidine

Cas:109384-19-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality N-BOC-4-Hydroxypiperidine

Cas:109384-19-2

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis

N-BOC-4-Hydroxypiperidine

Cas:109384-19-2

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

N-tert-Butoxycarbonyl-4-piperidinol

Cas:109384-19-2

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

N-BOC-4-Hydroxypiperidine Basic information Product Name: N-BOC-4-Hydroxypiperidine Synonyms: RARECHEM AH CK 0055;TERT-BUTYL 4-HYDROXYPIPERIDINE-1-CARBOXYLATE;TERT-BUTYL 4-HYDROXY-1-PIPE

N-BOC-4-Hydroxypiperidine 109384-19-2

Cas:109384-19-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Hebei Nengqian Chemical Import and Export Co., LTD.. is located in xingtai City, Hebei Province, China. It is a biotechnology enterprise engaged in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutica

N-BOC-4-Hydroxypiperidine CAS NO.109384-19-2

Cas:109384-19-2

Min.Order:1 Gram

FOB Price: $12.0 / 15.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 109384-19-2 with best quality

Cas:109384-19-2

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

N-BOC-4-Hydroxypiperidine 109384-19-2

Cas:109384-19-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

Beluga chemical professional supply High Quality N-BOC-4-Hydroxypiperidine CAS 109384-19-2 Why choose Beluga chemical 1. Beluga Chemical has a professional RESEARCH and development team and strong technical force to ensure technical support and r

High Quality N-BOC-4-Hydroxypiperidine CAS 109384-19-2

Cas:109384-19-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1-BOC-4-hydroxypiperidine

Cas:109384-19-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Minimum Order Qty. 10 Gram Supply Ability 500 Kilograms/Month Storage store in cool, dry, ventilated place 20℃ Delivery Time 3 business days after payment Payment Term TT,western union,Paypal,MoneyGram Package 10g,20g,50g,100g,500g,1KGS,

N-BOC-4-Hydroxypiperidine CAS NO.109384-19-2

Cas:109384-19-2

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Lonwin Chemical Group Limited

N-BOC-4-Hydroxypiperidine CAS: 109384-19-2 Specificatio Category Pharmaceutical Raw Materials, Fine Chemicals, Bulk drug Standard Medical standard Shelf life 2 years Storage should be stored in

Factory supply N-BOC-4-Hydroxypiperidine

Cas:109384-19-2

Min.Order:1 Kilogram

FOB Price: $100.0 / 150.0

Type:Other

inquiry

Wuhan Zenuo Biological Medicine Technology Co Ltd

Product Name: N-BOC-4-Hydroxypiperidine Synonyms: N - bok - 4 - hydroxy piperidine;N-BOC-4-HydroxypiperidineN-(tert-Butoxycarbonyl)-4-hydroxypiperidine;t-Butyl 4-hydroxypiperidine-1-carboxylate;Boc-(4-hydroxy)piperidine≥ 99% (GC);RARECHEM AH

N-BOC-4-Hydroxypiperidine Manufactory best quality

Cas:109384-19-2

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

N-BOC-4-Hydroxypiperidine

Cas:109384-19-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Triumph International Development Limilted

Appearance:white or light yellow crystalline powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:By

1-Boc-4-hydroxypiperidine

Cas:109384-19-2

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

N-BOC-4-hydroxypiperidine

Cas:109384-19-2

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

1-Boc-4-hydroxypiperidine

Cas:109384-19-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

tert-butyl 4-hydroxypiperidine-1-carboxylate

Cas:109384-19-2

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

Featured products N-Boc-4-piperidinol

Cas:109384-19-2

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

N-BOC-4-Hydroxypiperidine

Cas:109384-19-2

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

SHENGZHIKAI TECHNOLOGY INDUSTRY CO., LTD

Company Profile SHENGZHIKAI TECHNOLOGY INDUSTRY CO., LTD is a high-tech enterprise dedicated to the fields of fine chemical products.The scope of products covers pharmaceutical intermediates, plant extracts, chemical reagent, animal p

High Guality/Chemical intermediates/N-BOC-4-Hydroxypiperidine/109384-19-2

Cas:109384-19-2

Min.Order:1 Kilogram

FOB Price: $38.0 / 69.0

Type:Trading Company

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

lower price 109384-19-2 N-BOC-4-Hydroxypiperidine manufacturerAppearance:off-white to white powder Storage:dry place Package:according to customers' requirements Application:pharma intermediate Transportation:By air(EMS or EUB or FedEx or TNT ect...)

lower price 109384-19-2 N-BOC-4-Hydroxypiperidine manufacturer

Cas:109384-19-2

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

N-BOC-4-hydroxypiperidine

Cas:109384-19-2

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:10g/bag,or as your request Application:Used in organic synthesis Transportation:as

N-BOC-4-Hydroxypiperidine

Cas:109384-19-2

Min.Order:1 Gram

Negotiable

Type:Trading Company

inquiry

TaiChem Taizhou Limited

Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site

N-BOC-4-Hydroxypiperidine

Cas:109384-19-2

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Kunsui Technology Co., Ltd.

1. A strong scientific research team . 2. Stable quality (with a complete scientific research center and testing center to ensure the quality stability of each batch of products). 3. Rich export experience (with practical experience in exporting to m

Pharmaceutical N-BOC-4-Hydroxypiperidine Powder CAS 109384-19-2

Cas:109384-19-2

Min.Order:1 Kilogram

FOB Price: $8.2 / 8.8

Type:Trading Company

inquiry

Synthetic route

4-HYDROXYPIPERIDINE
5382-16-1

4-HYDROXYPIPERIDINE

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

Conditions
ConditionsYield
With sodium hydroxide In water; tert-butyl alcohol at 20℃;100%
With sodium carbonate In dichloromethane; water for 72h;100%
With sodium carbonate In dichloromethane; water for 72h; Inert atmosphere;100%
N-tert-butyloxycarbonylpiperidin-4-one
79099-07-3

N-tert-butyloxycarbonylpiperidin-4-one

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

Conditions
ConditionsYield
With sodium tetrahydroborate In ethanol100%
Stage #1: N-tert-butyloxycarbonylpiperidin-4-one With sodium tetrahydroborate In ethanol at 0 - 20℃; for 4h;
Stage #2: With water; ammonium chloride In ethanol
100%
With sodium hydroxide; sodium borohydrid In methanol100%
4-HYDROXYPIPERIDINE
5382-16-1

4-HYDROXYPIPERIDINE

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

Conditions
ConditionsYield
With tert-butyldicarbonate; triethylamine In dichloromethane at 0℃; for 21h;100%
4-HYDROXYPIPERIDINE
5382-16-1

4-HYDROXYPIPERIDINE

tert-butyldicarbonate
34619-03-9

tert-butyldicarbonate

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

Conditions
ConditionsYield
With sodium hydrogencarbonate In dichloromethane for 15h;100%
In tetrahydrofuran at 20℃;98.3%
With triethylamine In tetrahydrofuran at 20℃;98.3%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

piperidin-4-ol hydrochloride
5382-17-2

piperidin-4-ol hydrochloride

sodium hydrogencarbonate
144-55-8

sodium hydrogencarbonate

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

Conditions
ConditionsYield
In 1,4-dioxane100%
In 1,4-dioxane100%
pyridin-4-ol
626-64-2

pyridin-4-ol

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

Conditions
ConditionsYield
Stage #1: pyridin-4-ol With chloro(1,5-cyclooctadiene)rhodium(I) dimer; borane-ammonia complex In 2,2,2-trifluoroethanol at 50℃; for 24h; Inert atmosphere; Schlenk technique; Sealed tube;
Stage #2: di-tert-butyl dicarbonate With triethylamine In 2,2,2-trifluoroethanol at 20℃; Inert atmosphere; Schlenk technique; Sealed tube;
99%
4-HYDROXYPIPERIDINE
5382-16-1

4-HYDROXYPIPERIDINE

carbon monoxide
201230-82-2

carbon monoxide

tert-butyl alcohol
75-65-0

tert-butyl alcohol

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

Conditions
ConditionsYield
With 2C7H9N4*Au(1+)*Cu(1+)*2I(1-) In toluene at 90℃; for 8h; Autoclave;98%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran; ethyl acetate95%
Multi-step reaction with 2 steps
1: triethylamine / water; 1,4-dioxane / 0 - 20 °C
2: sodium tetrahydroborate; methanol / 0 - 20 °C
View Scheme
Multi-step reaction with 2 steps
1: triethylamine / dichloromethane / 0.8 h / 0 - 20 °C
2: sodium tetrahydroborate; methanol / 0.01 h / 0 - 20 °C
View Scheme
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

A

t-butyl piperidinecarboxylate
75844-69-8

t-butyl piperidinecarboxylate

B

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran; ethyl acetateA n/a
B 94%
With triethylamine In tetrahydrofuran; ethyl acetateA n/a
B 94%
With triethylamine In tetrahydrofuran; ethyl acetateA n/a
B 94%
tert-butyl 4-((4-methoxybenzyl)oxy)piperidine-1-carboxylate
1311186-22-7

tert-butyl 4-((4-methoxybenzyl)oxy)piperidine-1-carboxylate

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

Conditions
ConditionsYield
With N,N,N,N-tetraethylammonium tetrafluoroborate In methanol Electrochemical reaction;81%
t-butyl piperidinecarboxylate
75844-69-8

t-butyl piperidinecarboxylate

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

Conditions
ConditionsYield
With D-glucose; cells of Sphingomonas sp. HXN-200 In phosphate buffer at 30℃; for 2h; pH=8.0;69.5%
4-[(1-{tert-butoxycarbonyl}-4-piperidinyl)oxy]-1-(1-methylethyl)pyridinium iodide
845305-79-5

4-[(1-{tert-butoxycarbonyl}-4-piperidinyl)oxy]-1-(1-methylethyl)pyridinium iodide

A

tert-butyl 4-{[1-(1-methylethyl)-4-piperidinyl]oxy}-1-piperidinecarboxylate
845305-80-8

tert-butyl 4-{[1-(1-methylethyl)-4-piperidinyl]oxy}-1-piperidinecarboxylate

B

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

Conditions
ConditionsYield
With platinum (IV) oxide; hydrogen In ethanol at 20℃; under 2587.76 Torr; for 144h;A 54%
B 20%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

piperidin-4-ol hydrochloride
5382-17-2

piperidin-4-ol hydrochloride

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

Conditions
ConditionsYield
With sodium hydroxide In water at 25℃; for 1h;
Methoxyallene
13169-00-1

Methoxyallene

N-tert-butyloxycarbonylpiperidin-4-one
79099-07-3

N-tert-butyloxycarbonylpiperidin-4-one

A

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

B

N-(tert-butoxycarbonyl)-4-[(Z)-3-methoxyprop-2-enyl]piperidin-4-ol

N-(tert-butoxycarbonyl)-4-[(Z)-3-methoxyprop-2-enyl]piperidin-4-ol

C

N-(tert-butoxycarbonyl)-4-[(E)-3-methoxyprop-2-enyl]piperidin-4-ol

N-(tert-butoxycarbonyl)-4-[(E)-3-methoxyprop-2-enyl]piperidin-4-ol

Conditions
ConditionsYield
With N,N,N,N,N,N-hexamethylphosphoric triamide; samarium diiodide; tert-butyl alcohol In tetrahydrofuran at 20℃; Title compound not separated from byproducts;
C13H18BrN3O2
950848-59-6

C13H18BrN3O2

N-tert-butyloxycarbonylpiperidin-4-one
79099-07-3

N-tert-butyloxycarbonylpiperidin-4-one

A

C23H35BrN4O4
950848-60-9

C23H35BrN4O4

B

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

Conditions
ConditionsYield
Stage #1: C18H26BrN3O4 With trifluoroacetic acid In dichloromethane for 0.5h;
Stage #2: C13H18BrN3O2; N-tert-butyloxycarbonylpiperidin-4-one With sodium tris(acetoxy)borohydride; triethylamine In 1,2-dichloro-ethane at 20℃; for 16h;
Stage #3: With water; sodium hydrogencarbonate In dichloromethane; 1,2-dichloro-ethane
sodium potassium tartrate tetrahydrate

sodium potassium tartrate tetrahydrate

N-tert-butyloxycarbonylpiperidin-4-one
79099-07-3

N-tert-butyloxycarbonylpiperidin-4-one

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

Conditions
ConditionsYield
With diisobutylaluminium hydride In tetrahydrofuran; toluene
3-(1-tert-butoxycarbonylpiperidin-4-yloxy)benzoic acid
250681-69-7

3-(1-tert-butoxycarbonylpiperidin-4-yloxy)benzoic acid

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

titanium(IV) isopropylate
546-68-9

titanium(IV) isopropylate

N-tert-butyloxycarbonylpiperidin-4-one
79099-07-3

N-tert-butyloxycarbonylpiperidin-4-one

2-phenyl-3-keto-piperazine
5368-28-5

2-phenyl-3-keto-piperazine

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

Conditions
ConditionsYield
With sodium cyanoborohydride In methanol
4-[3-(N-BOC-Piperidin-4-yl)propyl]benzoic acid
163210-39-7

4-[3-(N-BOC-Piperidin-4-yl)propyl]benzoic acid

A

4-[3-(Piperidin-4-yl)propyl]benzoyl-2(S)-phenyl-sulfonylamino-β-alanine

4-[3-(Piperidin-4-yl)propyl]benzoyl-2(S)-phenyl-sulfonylamino-β-alanine

B

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

4-piperidone monohydrochloride monohydrate
40064-34-4

4-piperidone monohydrochloride monohydrate

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

Conditions
ConditionsYield
With sodium borohydrid; N-ethyl-N,N-diisopropylamine In N-methyl-acetamide; ethanol; water
4-HYDROXYPIPERIDINE
5382-16-1

4-HYDROXYPIPERIDINE

3-(1-tert-butoxycarbonylpiperidin-4-yloxy)benzoic acid
250681-69-7

3-(1-tert-butoxycarbonylpiperidin-4-yloxy)benzoic acid

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

Conditions
ConditionsYield
With triethylamine In dichloromethane
4-HYDROXYPIPERIDINE
5382-16-1

4-HYDROXYPIPERIDINE

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

A

4-[(1H-benzimidazol-2-ylmethyl)-(5,6,7,8-tetrahydroquinolin-8-yl)-amino]-piperidine-1-carboxylic Acid Amide (Hydrobromide Salt)
558448-73-0

4-[(1H-benzimidazol-2-ylmethyl)-(5,6,7,8-tetrahydroquinolin-8-yl)-amino]-piperidine-1-carboxylic Acid Amide (Hydrobromide Salt)

B

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

Conditions
ConditionsYield
In tetrahydrofuran
(R)-1-cyclohexyl-4-phenyl-3-(piperidin-4-yl)imidazolidin-2-one
926291-23-8

(R)-1-cyclohexyl-4-phenyl-3-(piperidin-4-yl)imidazolidin-2-one

N-tert-butyloxycarbonylpiperidin-4-one
79099-07-3

N-tert-butyloxycarbonylpiperidin-4-one

A

4-((R)-3-cyclohexyl-2-oxo-5-phenyl-imidazolidin-1-yl)-[1,4']bipiperidinyl-1'-carboxylic acid tert-butyl ester
1032818-37-3

4-((R)-3-cyclohexyl-2-oxo-5-phenyl-imidazolidin-1-yl)-[1,4']bipiperidinyl-1'-carboxylic acid tert-butyl ester

B

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

Conditions
ConditionsYield
With sodium cyanoborohydride; acetic acid In methanol at 60℃; for 16h;
4-HYDROXYPIPERIDINE
5382-16-1

4-HYDROXYPIPERIDINE

tert-butyl chloroformate
24608-52-4

tert-butyl chloroformate

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

Conditions
ConditionsYield
With triethylamine
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

4-hydroxypiperazine
69395-49-9

4-hydroxypiperazine

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 5h;34 g
tert-butyl 4-(tosyloxy)piperidin-1-carboxylate
118811-07-7

tert-butyl 4-(tosyloxy)piperidin-1-carboxylate

C9H15ClMg
245507-96-4

C9H15ClMg

A

C19H33NO2

C19H33NO2

B

N-Boc-1,2,3,6-tetrahydropyridine
85838-94-4

N-Boc-1,2,3,6-tetrahydropyridine

C

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

Conditions
ConditionsYield
With dilithium tetrachlorocuprate In tetrahydrofuran at 40℃;
1-(tert-butoxycarbonyl)piperidin-4-yl methanesulfonate
141699-59-4

1-(tert-butoxycarbonyl)piperidin-4-yl methanesulfonate

C9H15ClMg
245507-96-4

C9H15ClMg

A

C19H33NO2

C19H33NO2

B

N-Boc-1,2,3,6-tetrahydropyridine
85838-94-4

N-Boc-1,2,3,6-tetrahydropyridine

C

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

Conditions
ConditionsYield
With copper dichloride In tetrahydrofuran at 20℃;
p-toluenesulfonyl chloride
98-59-9

p-toluenesulfonyl chloride

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

tert-butyl 4-(tosyloxy)piperidin-1-carboxylate
118811-07-7

tert-butyl 4-(tosyloxy)piperidin-1-carboxylate

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 20h;100%
at 20℃; for 20h;99%
With triethylamine In dichloromethane at 20℃;89%
methanesulfonyl chloride
124-63-0

methanesulfonyl chloride

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

1-(tert-butoxycarbonyl)piperidin-4-yl methanesulfonate
141699-59-4

1-(tert-butoxycarbonyl)piperidin-4-yl methanesulfonate

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 5℃; for 3h;100%
With triethylamine In dichloromethane at 0 - 20℃; for 2.16667h;100%
With triethylamine In dichloromethane at 0 - 20℃; for 2.16667h;100%
acetic anhydride
108-24-7

acetic anhydride

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

2-methylpropan-2-yl 4-(acetyloxy)piperidine-1-carboxylate
850452-53-8

2-methylpropan-2-yl 4-(acetyloxy)piperidine-1-carboxylate

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 5h;100%
With dmap; triethylamine In dichloromethane at 0 - 20℃;55.17%
In pyridine at 25℃; for 6h;
With pyridine at 20℃;3 g
With pyridine at 20℃; for 5h;3 g
2-fluorobenzonitrile
394-47-8

2-fluorobenzonitrile

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

4-(2-cyano-phenoxy)-piperidine-1-carboxylic acid tert-butyl ester
647014-70-8

4-(2-cyano-phenoxy)-piperidine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide at 20 - 50℃;100%
With (E)-[4-(hydroxy)piperidin-1-ylsulphonyl]-2-(3-pyridyl)ethene In DMF (N,N-dimethyl-formamide) for 15h;
Stage #1: t-butyl 4-hydroxy piperidine-1-carboxylate With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃; for 2h;
Stage #2: 2-fluorobenzonitrile at 50℃; for 1h;
1-chloroisoquinoline
19493-44-8

1-chloroisoquinoline

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

1-tert-butoxycarbonyl-4-(1-isoquinolinyloxy)-piperidine
817187-34-1

1-tert-butoxycarbonyl-4-(1-isoquinolinyloxy)-piperidine

Conditions
ConditionsYield
With crown ether; potassium tert-butylate In DMF (N,N-dimethyl-formamide) at 20℃;100%
salicylonitrile
611-20-1

salicylonitrile

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

2-(piperidin-4-yloxy)-benzonitrile hydrochloride

2-(piperidin-4-yloxy)-benzonitrile hydrochloride

Conditions
ConditionsYield
Stage #1: salicylonitrile; t-butyl 4-hydroxy piperidine-1-carboxylate With di-tert-butyl-diazodicarboxylate; triphenylphosphine In tetrahydrofuran at 20℃; for 18h;
Stage #2: With hydrogenchloride; water In 1,4-dioxane at 20℃; for 18h;
100%
4-chlorpyridine hydrochloride
7379-35-3

4-chlorpyridine hydrochloride

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

2-(piperidin-4-yloxy)pyridine
127806-46-6

2-(piperidin-4-yloxy)pyridine

Conditions
ConditionsYield
In tetrahydrofuran; dimethyl sulfoxide100%
In tetrahydrofuran; dimethyl sulfoxide100%
In tetrahydrofuran; dimethyl sulfoxide100%
4-(4-chlorophenoxy)phenol
21567-18-0

4-(4-chlorophenoxy)phenol

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

tert-butyl 4-[4-(4-chloro-phenoxy)-phenoxy]-piperidine-1-carboxylate

tert-butyl 4-[4-(4-chloro-phenoxy)-phenoxy]-piperidine-1-carboxylate

Conditions
ConditionsYield
With di-isopropyl azodicarboxylate; triphenylphosphine In tetrahydrofuran at 0 - 47℃; for 65.1667h;100%
2-(4-hydroxyphenyl)-5-methyl-2H-pyrazole-3-carboxylic acid cyclohexylamide
946859-60-5

2-(4-hydroxyphenyl)-5-methyl-2H-pyrazole-3-carboxylic acid cyclohexylamide

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

4-[4-(5-cyclohexylcarbamoyl-3-methylpyrazol-1-yl)phenoxy]piperidine-1-carboxylic acid tert-butyl ester
946859-61-6

4-[4-(5-cyclohexylcarbamoyl-3-methylpyrazol-1-yl)phenoxy]piperidine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With di-isopropyl azodicarboxylate; triphenylphosphine In tetrahydrofuran at 20℃;100%
2-chloropyrazin
14508-49-7

2-chloropyrazin

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

t-butyl 4-[(pyrazin-2-yl)oxy]piperidine-1-carboxylate
442199-08-8

t-butyl 4-[(pyrazin-2-yl)oxy]piperidine-1-carboxylate

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃; for 2h;100%
In hexane; dimethyl sulfoxide; ethyl acetate
4-trifluoromethoxybenzyl bromide
50824-05-0

4-trifluoromethoxybenzyl bromide

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

4-[(4-trifluoromethoxy)phenyl]methoxypiperidine-1-formic acid tert-butyl ester
287952-21-0

4-[(4-trifluoromethoxy)phenyl]methoxypiperidine-1-formic acid tert-butyl ester

Conditions
ConditionsYield
Stage #1: t-butyl 4-hydroxy piperidine-1-carboxylate With sodium t-butanolate In 1,2-dimethoxyethane at 2 - 17℃; for 0.5h;
Stage #2: 4-trifluoromethoxybenzyl bromide In 1,2-dimethoxyethane at 12 - 23℃; for 3h;
100%
Stage #1: t-butyl 4-hydroxy piperidine-1-carboxylate With sodium hydride In N,N-dimethyl-formamide; mineral oil for 0.5h; Cooling with ice;
Stage #2: 4-trifluoromethoxybenzyl bromide In N,N-dimethyl-formamide; mineral oil at 20℃; for 15h; Cooling with ice;
78%
Stage #1: t-butyl 4-hydroxy piperidine-1-carboxylate With sodium hydride In N,N-dimethyl-formamide; mineral oil for 0.5h; Cooling with ice;
Stage #2: 4-trifluoromethoxybenzyl bromide In N,N-dimethyl-formamide; mineral oil at 20℃; for 15h;
78%
chloroacetic acid pyrrolidide
20266-00-6

chloroacetic acid pyrrolidide

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

tert-butyl 4-(2-oxo-2-(pyrrolidin-1-yl)ethoxy)piperidine-1-carboxylate
1174044-60-0

tert-butyl 4-(2-oxo-2-(pyrrolidin-1-yl)ethoxy)piperidine-1-carboxylate

Conditions
ConditionsYield
With trifluoroacetic acid; sodium hydroxide In water; toluene at 25℃;100%
4,6-dichloropyrimidine
1193-21-1

4,6-dichloropyrimidine

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

tert-butyl 4-((6-chloropyrimidin-4-yl)oxy)piperidine-1-carboxylate
442199-19-1

tert-butyl 4-((6-chloropyrimidin-4-yl)oxy)piperidine-1-carboxylate

Conditions
ConditionsYield
Stage #1: t-butyl 4-hydroxy piperidine-1-carboxylate With sodium hydride In tetrahydrofuran; mineral oil at 60℃; for 1h;
Stage #2: 4,6-dichloropyrimidine In tetrahydrofuran; mineral oil at 20℃; for 2h;
100%
Stage #1: t-butyl 4-hydroxy piperidine-1-carboxylate With sodium hydride In tetrahydrofuran at 60℃; for 1h; Inert atmosphere;
Stage #2: 4,6-dichloropyrimidine In tetrahydrofuran at 20℃; for 2h;
72%
Stage #1: t-butyl 4-hydroxy piperidine-1-carboxylate With sodium hydride In tetrahydrofuran at 60℃; for 0.5h;
Stage #2: 4,6-dichloropyrimidine In tetrahydrofuran at 20℃;
59%
3-bromo-5-hydroxy-dipyrido[2,3-b;4',3'-d]pyrrole-9-carboxylic acid benzyl ester
1312756-30-1

3-bromo-5-hydroxy-dipyrido[2,3-b;4',3'-d]pyrrole-9-carboxylic acid benzyl ester

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

3-bromo-5-(1-tert-butoxycarbonyl-piperidin-4-yloxy)-dipyrido[2,3-b;4',3'-d]pyrrole-9-carboxylic acid benzyl ester
1312756-31-2

3-bromo-5-(1-tert-butoxycarbonyl-piperidin-4-yloxy)-dipyrido[2,3-b;4',3'-d]pyrrole-9-carboxylic acid benzyl ester

Conditions
ConditionsYield
With diethylazodicarboxylate; triphenylphosphine In tetrahydrofuran at 50℃; for 1h;100%
methyl 6-(2,6-difluoro-4-hydroxyphenyl)-5-fluoropyridine-2-carboxylate
1355011-30-1

methyl 6-(2,6-difluoro-4-hydroxyphenyl)-5-fluoropyridine-2-carboxylate

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

methyl 6-(4-((1-(tert-butoxycarbonyl)piperidin-4-yl)oxy)-2,6-difluorophenyl)-5-fluoropicolinate
1395284-49-7

methyl 6-(4-((1-(tert-butoxycarbonyl)piperidin-4-yl)oxy)-2,6-difluorophenyl)-5-fluoropicolinate

Conditions
ConditionsYield
With di-isopropyl azodicarboxylate; triphenylphosphine In tetrahydrofuran at 20℃;100%
2-chloro-6-trifluoromethylpyridine
39890-95-4

2-chloro-6-trifluoromethylpyridine

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

tert-butyl 4-{[6-(trifluoromethyl)pyridin-2-yl]oxy}piperidine-1-carboxylate

tert-butyl 4-{[6-(trifluoromethyl)pyridin-2-yl]oxy}piperidine-1-carboxylate

Conditions
ConditionsYield
Stage #1: t-butyl 4-hydroxy piperidine-1-carboxylate With sodium hydride In tetrahydrofuran; mineral oil at 20℃; for 1h;
Stage #2: 2-chloro-6-trifluoromethylpyridine In tetrahydrofuran; mineral oil at 20℃; for 48h;
100%
propargyl bromide
106-96-7

propargyl bromide

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

tert-butyl 4-(prop-2-yn-1-yloxy)piperidine-1-carboxylate
1219827-56-1

tert-butyl 4-(prop-2-yn-1-yloxy)piperidine-1-carboxylate

Conditions
ConditionsYield
Stage #1: t-butyl 4-hydroxy piperidine-1-carboxylate With sodium hydride In tetrahydrofuran; mineral oil at 0℃; for 0.5h;
Stage #2: propargyl bromide In tetrahydrofuran; mineral oil at 25℃; for 12h;
100%
Stage #1: t-butyl 4-hydroxy piperidine-1-carboxylate With sodium hydride In tetrahydrofuran; mineral oil at 0℃; for 0.5h; Inert atmosphere;
Stage #2: propargyl bromide In tetrahydrofuran; mineral oil at 25℃; for 12h; Inert atmosphere;
100%
Stage #1: t-butyl 4-hydroxy piperidine-1-carboxylate With sodium hydride In tetrahydrofuran; mineral oil at 0℃; for 0.5h; Inert atmosphere;
Stage #2: propargyl bromide In tetrahydrofuran; mineral oil at 25℃; for 12h; Inert atmosphere;
100%
In tetrahydrofuran; toluene; mineral oil
N-[(5-chloro-2-ethylsulfonylphenyl)methyl]-4-hydroxy-3-(trifluoromethyl)benzamide

N-[(5-chloro-2-ethylsulfonylphenyl)methyl]-4-hydroxy-3-(trifluoromethyl)benzamide

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

4-[4-[(5-chloro-2-ethylsulfonylphenyl)methylcarbamoyl]-2-(trifluoromethyl)phenoxy]piperidine-1-carboxylic acid tert-butyl ester

4-[4-[(5-chloro-2-ethylsulfonylphenyl)methylcarbamoyl]-2-(trifluoromethyl)phenoxy]piperidine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With di-isopropyl azodicarboxylate; triphenylphosphine In tetrahydrofuran at 20 - 50℃; for 19h;100%
2,5-dichloro-4-(trifluoromethyl)pyridine
89719-92-6

2,5-dichloro-4-(trifluoromethyl)pyridine

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

tert-butyl 4-((5-chloro-4-(trifluoromethyl)pyridin-2-yl)oxy)piperidine-1-carboxylate

tert-butyl 4-((5-chloro-4-(trifluoromethyl)pyridin-2-yl)oxy)piperidine-1-carboxylate

Conditions
ConditionsYield
Stage #1: t-butyl 4-hydroxy piperidine-1-carboxylate With sodium hydride In 1,2-dimethoxyethane; mineral oil at 20℃; for 1h; Inert atmosphere;
Stage #2: 2,5-dichloro-4-(trifluoromethyl)pyridine In 1,2-dimethoxyethane; mineral oil for 2h; Inert atmosphere; Reflux;
100%
2-chloro-4-fluorobenzylbromide
45767-66-6

2-chloro-4-fluorobenzylbromide

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

tert-butyl 4-((2-chloro-4-fluorobenzyl)oxy)piperidine-1-carboxylate

tert-butyl 4-((2-chloro-4-fluorobenzyl)oxy)piperidine-1-carboxylate

Conditions
ConditionsYield
Stage #1: t-butyl 4-hydroxy piperidine-1-carboxylate With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 1h;
Stage #2: 2-chloro-4-fluorobenzylbromide With tetra-(n-butyl)ammonium iodide In N,N-dimethyl-formamide; mineral oil at 20℃; for 48h;
100%
5-bromo-2,3-dichloropyridine
97966-00-2

5-bromo-2,3-dichloropyridine

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

tert-butyl 4-((5-bromo-3-chloropyridin-2-yl)oxy)piperidine-1-carboxylate

tert-butyl 4-((5-bromo-3-chloropyridin-2-yl)oxy)piperidine-1-carboxylate

Conditions
ConditionsYield
Stage #1: t-butyl 4-hydroxy piperidine-1-carboxylate With sodium hydride In N,N-dimethyl-formamide; mineral oil at 20℃; for 1h;
Stage #2: 5-bromo-2,3-dichloropyridine In N,N-dimethyl-formamide; mineral oil at 70℃; for 16h;
100%
Stage #1: t-butyl 4-hydroxy piperidine-1-carboxylate With sodium hydride In N,N-dimethyl acetamide at 20℃; for 1h;
Stage #2: 5-bromo-2,3-dichloropyridine In N,N-dimethyl acetamide at 80℃; Inert atmosphere;
57%
methyl 4-hydroxy-2-methoxybenzoate
28478-46-8

methyl 4-hydroxy-2-methoxybenzoate

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

4-(N-t-Butoxycarbonyl-4-piperidinyloxy)-2-methoxybenzoic acid methyl ester
162045-37-6

4-(N-t-Butoxycarbonyl-4-piperidinyloxy)-2-methoxybenzoic acid methyl ester

Conditions
ConditionsYield
With di-isopropyl azodicarboxylate; triphenylphosphine In tetrahydrofuran at 0 - 40℃; for 2h; Inert atmosphere; Sonication;100%
2-hydroxyl nicotinic acid ethyl ester
27805-12-5

2-hydroxyl nicotinic acid ethyl ester

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

C18H26N2O5

C18H26N2O5

Conditions
ConditionsYield
With di-isopropyl azodicarboxylate; triphenylphosphine In tetrahydrofuran at 20℃; for 4h; Mitsunobu Displacement;100%
6-methoxypyridine-3-ol
51834-97-0

6-methoxypyridine-3-ol

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

tert-butyl 4-((6-methoxypyridin-3-yl)oxy)piperidine-1-carboxylate

tert-butyl 4-((6-methoxypyridin-3-yl)oxy)piperidine-1-carboxylate

Conditions
ConditionsYield
With triphenylphosphine In tetrahydrofuran at 20℃; for 9h; Inert atmosphere;100%
With di-isopropyl azodicarboxylate; triphenylphosphine In tetrahydrofuran at 40℃; for 1h; Inert atmosphere;
With di-isopropyl azodicarboxylate; triphenylphosphine In tetrahydrofuran at 40℃; for 1h; Inert atmosphere;
methanesulfonyl chloride
124-63-0

methanesulfonyl chloride

t-butyl 4-hydroxy piperidine-1-carboxylate
109384-19-2

t-butyl 4-hydroxy piperidine-1-carboxylate

1-(tert-butoxycarbonyl)piperidin-4-yl methanesulfonate
141699-59-4

1-(tert-butoxycarbonyl)piperidin-4-yl methanesulfonate

Conditions
ConditionsYield
With triethylamine In dichloromethane; ethyl acetate100%
With triethylamine In dichloromethane; ethyl acetate100%
With triethylamine In dichloromethane; ethyl acetate100%

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