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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis

D-4-Chlorophenylalanine

Cas:14091-08-8

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

3-(4-Chlorophenyl)-D-alanine

Cas:14091-08-8

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so

D-phe(4-Cl)-OH 14091-08-8

Cas:14091-08-8

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

D-4-Chlorophenylalanine CAS NO.14091-08-8

Cas:14091-08-8

Min.Order:1 Gram

FOB Price: $1.0 / 99.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 14091-08-8 with competitive price

Cas:14091-08-8

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Chemical Name: D-4-Chlorophenylalanine Cas No.: 14091-08-8 Molecular Formula: C9H10ClNO2 Molecular Weight: 199.63 Specification: >98%; ee%>98%; Appearance: white powde

D-4-Chlorophenylalanine

Cas:14091-08-8

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Hebei yanxi chemical co.,LTD.

Hebei Yanxi Chemical Co., Ltd. is a professional research, development and production of lead acetate benzene acetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low car

D-4-Chlorophenylalanine

Cas:14091-08-8

Min.Order:1 Metric Ton

FOB Price: $1.0 / 2.0

Type:Manufacturers

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the

D-Phenylalanine,4-chloro-/ LIDE PHARMA- Factory supply / Best price

Cas:14091-08-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Minimum Order Qty. 10 Gram Supply Ability 500 Kilograms/Month Storage store in cool, dry, ventilated place 20℃ Delivery Time 3 business days after payment Payment Term TT,western union,Paypal,MoneyGram Package 10g,20g,50g,100g,500g,1KGS,

D-4-Chlorophenylalanine CAS NO.14091-08-8

Cas:14091-08-8

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

D-Phenylalanine,4-chloro-

Cas:14091-08-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

D-4-Chlorophenylalanine

Cas:14091-08-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

4-Chloro-D-phenylalanine

Cas:14091-08-8

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

Hot Sales D-4-Chlorophe CAS NO.14091-08-8 CAS NO.14091-08-8

Cas:14091-08-8

Min.Order:1 Metric Ton

FOB Price: $7.0 / 8.0

Type:Trading Company

inquiry

Hangzhou Zhongqi chem Co.,Ltd.

Located in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service and h

D-Phenylalanine,4-chloro-

Cas:14091-08-8

Min.Order:0

Negotiable

Type:Other

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

4-Chloro-D-phenylalanine

Cas:14091-08-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

SAGECHEM LIMITED

SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in custom synthe

SAGECHEM/ D-4-Chlorophenylalanine

Cas:14091-08-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

D-4-Chlorophenylalanine

Cas:14091-08-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

D-4-Chlorophenylalanine

Cas:14091-08-8

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Hangzhou ZeErRui Chemical Co., Ltd.

Product name:D-4-Chlorophenylalanine Synonym:4-Chloro-D-phenylalanine;D-PCP,D-PCPA;H-D-Phe(4-Cl)-OH·HCl; CAS No:14091-08-8 Molecular Formula:C9H10ClNO2 Molecular Weight:199.63 【Quality Standard】

D-4-Chlorophenylalanine china manufacture

Cas:14091-08-8

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

D-4-Chlorophenylalanine cas no. 14091-08-8 98%

Cas:14091-08-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Research Peptide Biotechnology Co., Ltd.

High purity, high success rate, short cycle and moderate priceAppearance:White powder solid Storage:Negative 20 degrees Celsius Package:5mg, 10mg 100mg, 1gram Application:Applied to various scientific research

D-Phenylalanine,4-chloro-

Cas:14091-08-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

D-4-chlorophenylalanine

Cas:14091-08-8

Min.Order:0

Negotiable

Type:Other

inquiry

Wuxi TAA Chemical Industry Co.,LTD.

1.A strong technical force and advanced processing equipments. The quality of the products has been strictly inspected and all kinds of index have reached or exceeded domestic and international standards.2. Now we have established long-term stable re

D-phe(4-Cl)-OH 14091-08-8 CAS 14091-08-8

Cas:14091-08-8

Min.Order:0

Negotiable

Type:Other

inquiry

Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec 4-chloro-d-phenylalanine C36130 1g

Cas:14091-08-8

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

D-4-Chlorophenylalanine

Cas:14091-08-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

GL Biochem (Shanghai) Ltd.

Application:Intermidates

H-D-Phe(4-Cl)-OH

Cas:14091-08-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

D-4-chlorophenylalanine

Cas:14091-08-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Ocean Chemical Co., Ltd.

★.Best quality according to requirement ★.Competitive price in China market ★.Mature Technical support ★.Professional logistic support

4-Chloro-D-Phenylalanine

Cas:14091-08-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Guangdong Juda Chemical Industrial Co.,Limited

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by courier/air/sea Port:Any port of China

4-Chloro-D-phenylalanine 14091-08-8 CAS NO.: 14091-08-8

Cas:14091-08-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Wuhan Circle Star Chem-medical Technology co.,Ltd.

good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:25kg,50kg,180kg,200kg,250kg,1000kg,customization Application:Pharma;Industry;Agricultural;chemical reaserch Tran

D-4-Chlorophenylalanine

Cas:14091-08-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

C46H33Cl2N3NiO3

C46H33Cl2N3NiO3

A

para-Chloro-D-phenylalanine
14091-08-8

para-Chloro-D-phenylalanine

(S)-N-(2-benzoyl-4-chlorophenyl)-2-[3,5-dihydro-4H-dinaphth[2,1-c:1′,2′-e]azepin-4-yl]acetamide

(S)-N-(2-benzoyl-4-chlorophenyl)-2-[3,5-dihydro-4H-dinaphth[2,1-c:1′,2′-e]azepin-4-yl]acetamide

Conditions
ConditionsYield
With hydrogenchloride; water In methanol at 40℃; for 6h;A 95%
B 97%
With hydrogenchloride In methanol; water at 40℃; for 6h;A n/a
B 96%
C46H33Cl2N3NiO3

C46H33Cl2N3NiO3

A

para-Chloro-D-phenylalanine
14091-08-8

para-Chloro-D-phenylalanine

B

C37H27ClN2O2

C37H27ClN2O2

Conditions
ConditionsYield
With hydrogenchloride; water In methanol at 40℃; for 6h;A 96%
B 96%
DL-Phe(4Cl)
7424-00-2

DL-Phe(4Cl)

A

para-Chloro-D-phenylalanine
14091-08-8

para-Chloro-D-phenylalanine

B

β-(4-chlorophenyl)pyruvic acid
3617-01-4

β-(4-chlorophenyl)pyruvic acid

Conditions
ConditionsYield
With diaphorase; 2,6-Dichlorophenolindophenol; potassium chloride; oxygen; nicotiamide adenine dinucleotide at 15 - 20℃; pH=9.5; aq. buffer; Enzymatic reaction;A 78%
B n/a
DL-Phe(4Cl)
7424-00-2

DL-Phe(4Cl)

para-Chloro-D-phenylalanine
14091-08-8

para-Chloro-D-phenylalanine

Conditions
ConditionsYield
With sodium hydroxide; oxygen; 2-amino-2-hydroxymethyl-1,3-propanediol In water at 30℃; for 3h; pH=7.3; Resolution of racemate; Enzymatic reaction; enantioselective reaction;44%
With (S)-2-hydroxy-2'-(3-(N-phenylcarbamoylamino)benzyl)-1,1'-binaphthyl-3-carboxaldehyde In dimethyl sulfoxide Resolution of racemate; stereoselective reaction;n/a
With D-glucose; D-amino acid aminotransferase from Bacillus sp mutant T242G; L-aminoacid deaminase from Proteus mirabilis In aq. phosphate buffer at 37℃; for 4h; pH=8; Enzymatic reaction; enantioselective reaction;n/a
tert-butyl (R)-3-(4-chlorophenyl)-2-(diphenylmethanediylamino)propanoate
119244-26-7

tert-butyl (R)-3-(4-chlorophenyl)-2-(diphenylmethanediylamino)propanoate

para-Chloro-D-phenylalanine
14091-08-8

para-Chloro-D-phenylalanine

Conditions
ConditionsYield
With hydrogenchloride Yield given;
β-(4-chlorophenyl)pyruvic acid
3617-01-4

β-(4-chlorophenyl)pyruvic acid

para-Chloro-D-phenylalanine
14091-08-8

para-Chloro-D-phenylalanine

Conditions
ConditionsYield
With meso-2,6-D-diaminopimelic acid dehydrogenase mutant BC621; ammonium chloride; NADPH In various solvent(s) for 24h;
(±)-ethyl 2-amino-3-(4-chlorophenyl)propanoate
29622-19-3

(±)-ethyl 2-amino-3-(4-chlorophenyl)propanoate

A

L-4-chlorophenylalanine ethyl ester

L-4-chlorophenylalanine ethyl ester

B

p-chlorophenylalanine
14173-39-8

p-chlorophenylalanine

C

para-Chloro-D-phenylalanine
14091-08-8

para-Chloro-D-phenylalanine

D

D-4-chlorophenylalanine ethyl ester
166449-97-4

D-4-chlorophenylalanine ethyl ester

Conditions
ConditionsYield
With Bacillus licheniformis; sodium hydrogencarbonate; 1-ethyl-3-methylimidazolium acetate In water; water-d2 at 30℃; for 1h;
4-chlorobenzyl bromide
622-95-7

4-chlorobenzyl bromide

para-Chloro-D-phenylalanine
14091-08-8

para-Chloro-D-phenylalanine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 50percent aq. NaOH / cinchonidine catalyst / CH2Cl2 / 12 h / 25 °C
2: 6N HCl
View Scheme
DL-Phe(4Cl)
7424-00-2

DL-Phe(4Cl)

Benzeneacetamide
103-81-1

Benzeneacetamide

A

phenylacetic acid
103-82-2

phenylacetic acid

B

N-phenylacetyl-4-chloro-L-phenylalanine
482281-07-2

N-phenylacetyl-4-chloro-L-phenylalanine

C

para-Chloro-D-phenylalanine
14091-08-8

para-Chloro-D-phenylalanine

Conditions
ConditionsYield
Stage #1: DL-Phe(4Cl); Benzeneacetamide With recombinant Alcaligenes faecalis penicillin G acylase immobilized on oxirane acrylic carrier; potassium hydroxide In water at 35℃; for 3.66667h; pH=10; Enzymatic reaction;
Stage #2: With hydrogenchloride In water pH=1; optical yield given as %ee; enantioselective reaction;
4-chloro-(RS)-phenylalaninamide hydrochloride
1428149-31-8

4-chloro-(RS)-phenylalaninamide hydrochloride

A

p-chlorophenylalanine
14173-39-8

p-chlorophenylalanine

B

para-Chloro-D-phenylalanine
14091-08-8

para-Chloro-D-phenylalanine

Conditions
ConditionsYield
With pyridoxal 5'-phosphate monohydrate In aq. buffer at 40℃; for 24h; pH=8.0; Enzymatic reaction; Overall yield = > 99 %;A n/a
B n/a
With pyridoxal 5'-phosphate monohydrate; cobalt(II) chloride In aq. buffer at 40℃; for 36h; pH=7.0; Enzymatic reaction; Overall yield = > 99 %;A n/a
B n/a
DL-Phe(4Cl)
7424-00-2

DL-Phe(4Cl)

A

p-chlorophenylalanine
14173-39-8

p-chlorophenylalanine

B

para-Chloro-D-phenylalanine
14091-08-8

para-Chloro-D-phenylalanine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: thionyl chloride / 0 °C
2: ammonia / methanol / 0 °C
3: pyridoxal 5'-phosphate monohydrate; cobalt(II) chloride / aq. buffer / 36 h / 40 °C / pH 7.0 / Enzymatic reaction
View Scheme
With (S)-2-hydroxy-2'-(3-(N-phenylcarbamoylamino)benzyl)-1,1'-binaphthyl-3-carboxaldehyde In dimethyl sulfoxide Resolution of racemate; stereoselective reaction;A n/a
B n/a
With (R)-2-hydroxy-2'-(3-phenylurylbenzyl)-1,1'-binaphthyl-3-carboxaldehyde In dimethyl sulfoxide Resolution of racemate; stereoselective reaction;A n/a
B n/a
With phenylalanine ammonia-lyase from Pseudozyma antarctica yeast In aq. buffer at 30℃; for 17h; pH=8.5; Resolution of racemate; stereoselective reaction;A n/a
B n/a
2-amino-3-(4-chlorophenyl)propionic acid methyl ester hydrochloride
14173-40-1, 23434-91-5, 33965-47-8, 60594-65-2

2-amino-3-(4-chlorophenyl)propionic acid methyl ester hydrochloride

A

p-chlorophenylalanine
14173-39-8

p-chlorophenylalanine

B

para-Chloro-D-phenylalanine
14091-08-8

para-Chloro-D-phenylalanine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: ammonia / methanol / 0 °C
2: pyridoxal 5'-phosphate monohydrate; cobalt(II) chloride / aq. buffer / 36 h / 40 °C / pH 7.0 / Enzymatic reaction
View Scheme
N-Boc-D-(4-Cl)Phe-OH
57292-44-1

N-Boc-D-(4-Cl)Phe-OH

para-Chloro-D-phenylalanine
14091-08-8

para-Chloro-D-phenylalanine

Conditions
ConditionsYield
With trifluoroacetic acid In dichloromethane for 0.5h;
DL-Phe(4Cl)
7424-00-2

DL-Phe(4Cl)

A

para-Chloro-D-phenylalanine
14091-08-8

para-Chloro-D-phenylalanine

B

(S)-β-amino-β-(4-chlorophenyl)propionic acid
131690-60-3

(S)-β-amino-β-(4-chlorophenyl)propionic acid

Conditions
ConditionsYield
With phenylalanine 2,3-aminomutase from Pantoea agglomerans; ammonium carbonate at 20℃; for 20h; pH=8; Enzymatic reaction; enantioselective reaction;A n/a
B n/a
β-(4-chlorophenyl)pyruvic acid
3617-01-4

β-(4-chlorophenyl)pyruvic acid

A

p-chlorophenylalanine
14173-39-8

p-chlorophenylalanine

B

para-Chloro-D-phenylalanine
14091-08-8

para-Chloro-D-phenylalanine

Conditions
ConditionsYield
With pyridoxal 5'-phosphate; ethylenediaminetetraacetic acid; sodium diphenylglycine In aq. buffer at 50℃; pH=8; Overall yield = 24 %; enantioselective reaction;A n/a
B n/a
4-chlorobenzaldehyde
104-88-1

4-chlorobenzaldehyde

A

p-chlorophenylalanine
14173-39-8

p-chlorophenylalanine

B

para-Chloro-D-phenylalanine
14091-08-8

para-Chloro-D-phenylalanine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: ethanolamine
1.2: Alkaline conditions
2.1: sodium diphenylglycine; pyridoxal 5'-phosphate; ethylenediaminetetraacetic acid / aq. buffer / 50 °C / pH 8
View Scheme
p-chlorophenylalanine
14173-39-8

p-chlorophenylalanine

para-Chloro-D-phenylalanine
14091-08-8

para-Chloro-D-phenylalanine

Conditions
ConditionsYield
With L-amino acid deaminase from Proteus mirabilis; Burkholderia stabilis formate dehydrogenase; meso-diaminopimelate dehydrogenase from Symbiobacterium thermophilum mutant H227V; sodium formate; ammonium chloride; NADPH In aq. phosphate buffer at 45℃; pH=9; Enzymatic reaction;
DL-Phe(4Cl)
7424-00-2

DL-Phe(4Cl)

A

3-(4-chlorophenyl)prop-2-enoic acid
1615-02-7

3-(4-chlorophenyl)prop-2-enoic acid

B

para-Chloro-D-phenylalanine
14091-08-8

para-Chloro-D-phenylalanine

Conditions
ConditionsYield
With phenylalanine ammonia-lyase from Pseudozyma antarctica yeast In aq. buffer at 30℃; for 168h; pH=8.5; Reagent/catalyst; Time; Resolution of racemate; stereoselective reaction;A n/a
B n/a
para-Chloro-D-phenylalanine
14091-08-8

para-Chloro-D-phenylalanine

(R)-2-amino-3-(4-chlorophenyl)propan-1-ol
201863-99-2

(R)-2-amino-3-(4-chlorophenyl)propan-1-ol

Conditions
ConditionsYield
With lithium aluminium tetrahydride In tetrahydrofuran at 0℃; Reflux; Inert atmosphere;99%
para-Chloro-D-phenylalanine
14091-08-8

para-Chloro-D-phenylalanine

tert-butyl (2,4-dioxo-3-azaspiro[5,5]undecan-3-yl) carbonate

tert-butyl (2,4-dioxo-3-azaspiro[5,5]undecan-3-yl) carbonate

N-Boc-D-(4-Cl)Phe-OH
57292-44-1

N-Boc-D-(4-Cl)Phe-OH

Conditions
ConditionsYield
With triethylamine In water; acetone at 25℃; for 14h;90%
para-Chloro-D-phenylalanine
14091-08-8

para-Chloro-D-phenylalanine

N-Boc-D-(4-Cl)Phe-OH
57292-44-1

N-Boc-D-(4-Cl)Phe-OH

Conditions
ConditionsYield
With triethylamine In water; acetone at 20℃; for 44h;87.3%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

para-Chloro-D-phenylalanine
14091-08-8

para-Chloro-D-phenylalanine

N-Boc-D-(4-Cl)Phe-OH
57292-44-1

N-Boc-D-(4-Cl)Phe-OH

Conditions
ConditionsYield
With triethylamine In water; acetone at 20℃; for 44h;87.3%
C31H45N5O5

C31H45N5O5

para-Chloro-D-phenylalanine
14091-08-8

para-Chloro-D-phenylalanine

C40H53ClN6O6

C40H53ClN6O6

Conditions
ConditionsYield
With 1-hydroxy-7-aza-benzotriazole; diisopropyl-carbodiimide In DMF (N,N-dimethyl-formamide) at 20℃;
N-(spiro[5.5]undecan-3-yl)ethylenediamine

N-(spiro[5.5]undecan-3-yl)ethylenediamine

para-Chloro-D-phenylalanine
14091-08-8

para-Chloro-D-phenylalanine

trifluoroacetic acid
76-05-1

trifluoroacetic acid

(2S)-2-amino-N-(2-aminoethyl)-3-(4-chlorophenyl)-N-(spiro[5.5]undecan-3-yl)propanamide trifluoroacetic acid salt
949590-07-2

(2S)-2-amino-N-(2-aminoethyl)-3-(4-chlorophenyl)-N-(spiro[5.5]undecan-3-yl)propanamide trifluoroacetic acid salt

Conditions
ConditionsYield
Stage #1: N-(spiro[5.5]undecan-3-yl)ethylenediamine In N,N-dimethyl-formamide at 20℃; for 24h;
Stage #2: para-Chloro-D-phenylalanine With N-ethyl-N,N-diisopropylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate In dichloromethane at 20℃; for 20h;
Stage #3: trifluoroacetic acid With chlorotriisopropylsilane; ethane-1,2-dithiol In water at 20℃; for 1h; Further stages.;
2-[(2,1,3-benzothiadiazol-4-ylsulfonyl)amino]-4-chlorobenzoic acid
791098-17-4

2-[(2,1,3-benzothiadiazol-4-ylsulfonyl)amino]-4-chlorobenzoic acid

para-Chloro-D-phenylalanine
14091-08-8

para-Chloro-D-phenylalanine

C22H16Cl2N4O5S2
1202359-16-7

C22H16Cl2N4O5S2

Conditions
ConditionsYield
With pyridine; 2-(1H-9-azabenzotriazol-1-yl)-1,1,3,3-tetramethyluroniumhexafluorophosphate In N,N-dimethyl-formamide for 1h;
4-chloroisatoic anhydride
40928-13-0

4-chloroisatoic anhydride

para-Chloro-D-phenylalanine
14091-08-8

para-Chloro-D-phenylalanine

C16H14Cl2N2O3

C16H14Cl2N2O3

Conditions
ConditionsYield
With dmap In N,N-dimethyl-formamide at 50℃; for 12h;
4-chloro-2-nitro-benzoic acid
6280-88-2

4-chloro-2-nitro-benzoic acid

para-Chloro-D-phenylalanine
14091-08-8

para-Chloro-D-phenylalanine

C16H12Cl2N2O5

C16H12Cl2N2O5

Conditions
ConditionsYield
With pyridine; 2-(1H-9-azabenzotriazol-1-yl)-1,1,3,3-tetramethyluroniumhexafluorophosphate In N,N-dimethyl-formamide for 1h;
para-Chloro-D-phenylalanine
14091-08-8

para-Chloro-D-phenylalanine

4-chloro-2-nitro-benzoyl chloride
41995-04-4

4-chloro-2-nitro-benzoyl chloride

C16H12Cl2N2O5

C16H12Cl2N2O5

Conditions
ConditionsYield
In N,N-dimethyl-formamide
para-Chloro-D-phenylalanine
14091-08-8

para-Chloro-D-phenylalanine

A

N-(N-benzoyl-L-tryptophanyl)-para-chloro-D-phenylalanine methyl ester
1435265-79-4

N-(N-benzoyl-L-tryptophanyl)-para-chloro-D-phenylalanine methyl ester

B

N-(N-benzoyl-D-tryptophanyl)-para-chloro-D-phenylalanine methyl ester

N-(N-benzoyl-D-tryptophanyl)-para-chloro-D-phenylalanine methyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sulfuric acid / dichloromethane; trifluoroacetic acid / 2 h / Reflux
2: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / dichloromethane / 6 h / 20 °C
View Scheme
methanol
67-56-1

methanol

para-Chloro-D-phenylalanine
14091-08-8

para-Chloro-D-phenylalanine

D-p-chlorophenylalanine methyl ester
134166-72-6

D-p-chlorophenylalanine methyl ester

Conditions
ConditionsYield
With sulfuric acid In dichloromethane; trifluoroacetic acid for 2h; Reflux;
para-Chloro-D-phenylalanine
14091-08-8

para-Chloro-D-phenylalanine

2,2'-(propane-2,2-diyl)bis[(R)-4-(4-chlorobenzyl)-4,5-dihydrooxazole]
1487438-24-3

2,2'-(propane-2,2-diyl)bis[(R)-4-(4-chlorobenzyl)-4,5-dihydrooxazole]

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: lithium aluminium tetrahydride / tetrahydrofuran / 0 °C / Reflux; Inert atmosphere
2: zinc trifluoromethanesulfonate / toluene / 48 h / 20 °C / Inert atmosphere; Reflux
View Scheme

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