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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis

N-[1,1-Bis[(acetyloxy)methyl]-3-(4-octylphenyl)propyl]acetamide

Cas:162358-09-0

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

162358-09-0 N-[1,1-Bis[(acetyloxy)methyl]-3-(4-octylphenyl)propyl]acetamide

Cas:162358-09-0

Min.Order:1 Kilogram

FOB Price: $1000.0

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 162358-09-0 with competitive price

Cas:162358-09-0

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

high quality N-[1,1-Bis[(acetyloxy)methyl]-3-(4-octylphenyl)propyl]acetamide

Cas:162358-09-0

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

N-[1,1-Bis[(acetyloxy)methyl]-3-(4-octylphenyl)propyl]acetamide 162358-09-0

Cas:162358-09-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

N-[1,1-Bis[(acetyloxy)methyl]-3-(4-octylphenyl)propyl]acetamide

Cas:162358-09-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

N-[1,1-Bis[(acetyloxy)methyl]-3-(4-octylphenyl)propyl]acetamide

Cas:162358-09-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

N-[1,1-Bis[(acetyloxy)methyl]-3-(4-octylphenyl)propyl]acetamide

Cas:162358-09-0

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

high quality N-[1,1-Bis[(acetyloxy)methyl]-3-(4-octylphenyl)propyl]acetamide

Cas:162358-09-0

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

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Siwei Development Group Ltd.

Product name: N-[1,1-Bis[(Acetyloxy)Methyl]-3-(4-Octylphenyl)Propyl]Acetamide CAS No.:162358-09-0 Molecule Formula:C25H39NO5 Molecule Weight:433.58 Purity: 98.0% Package: 25kg/drum Description:White crystalline powder Manufacture Standards:Ent

Best Quality N-[1,1-Bis[(Acetyloxy)Methyl]-3-(4-Octylphenyl)Propyl]Acetamide

Cas:162358-09-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

N-[1,1-Bis[(acetyloxy)methyl]-3-(4-octylphenyl)propyl]acetamide

Cas:162358-09-0

Min.Order:1 Milligram

Negotiable

Type:Trading Company

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EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

high quality N-[1,1-Bis[(acetyloxy)methyl]-3-(4-octylphenyl)propyl]acetamide

Cas:162358-09-0

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

Hangzhou Huarong Pharm Co., Ltd.established since 2006 , has been actively developing specialty products for Finished Dosages, APIs, Intermediates, and Fine chemicals markets in North America, Europe, Korea, Japan, Mid-East and all over the World. Hu

N-[1,1-Bis[(acetyloxy)methyl]-3-(4-octylphenyl)propyl]acetamide

Cas:162358-09-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

high quality N-[1,1-Bis[(acetyloxy)methyl]-3-(4-octylphenyl)propyl]acetamide

Cas:162358-09-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

high quality N-[1,1-Bis[(acetyloxy)methyl]-3-(4-octylphenyl)propyl]acetamide

Cas:162358-09-0

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Hangzhou Zhongqi chem Co.,Ltd.

Located in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service an

N-(1,1-bis((acetyloxy)methyl)-3-(4-octylphenyl)propyl)acetamide

Cas:162358-09-0

Min.Order:1 Gram

Negotiable

Type:Other

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Triumph International Development Limilted

Triumph has the complete production of G- KG - MT service chain,we can make the new technology into productivity quickly in the research and development of new products. Main Business Custom Synthesis:

2-Acetamido-2-(4-octylphenethyl)propane-1,3-diyl diac

Cas:162358-09-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

N-[1, 1-bis[(acetyloxy)methyl]-3-(4-octylphenyl)propyl Aceamide Cas no.162358-09-0 98%

Cas:162358-09-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

high quality N-[1,1-Bis[(acetyloxy)methyl]-3-(4-octylphenyl)propyl]acetamide

Cas:162358-09-0

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Hebei Mojin Biotechnology Co.,Ltd

1, High quality with competitive price:2, Fast and safe delivery3.Excellent pre-sales and after-sales service4. Well-trained and professional technologist and sales with rich experience in the field for 5-10 yearsAppearance:see detailed specification

N-[1,1-Bis[(acetyloxy)methyl]-3-(4-octylphenyl)propyl]acetamide

Cas:162358-09-0

Min.Order:0

Negotiable

Type:Trading Company

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GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

N-[1,1-Bis[(acetyloxy)methyl]-3-(4-octylphenyl)propyl]acetamide

Cas:162358-09-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Dingyan Chem Co., Ltd

manufacture Application:The refence standard products, for lab use, also we could produce bigger quantity on yr requirement.

n-(1,1-bis((acetyloxy)methyl)-3-(4-octylphenyl)propyl)acetamide

Cas:162358-09-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec N-[1,1-Bis[(acetyloxy)methyl]-3-(4-octylphenyl)propyl]acetamide N47700 5mg

Cas:162358-09-0

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM is one of China's leading providers of integrated fine chemical services including offering, research and development, Custom manufacturing business, as well as other Value-added customer services, for diversified range products of chemicals

N-[1,1-Bis[(acetyloxy)methyl]-3-(4-octylphenyl)propyl]acetamide

Cas:162358-09-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

N-[1,1-Bis[(acetyloxy)methyl]-3-(4-octylphenyl)propyl]acetamide

Cas:162358-09-0

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

N-[1,1-Bis[(acetyloxy)methyl]-3-(4-octylphenyl)propyl]acetamide

Cas:162358-09-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

We are a trading company aiming at providing high-quality services to customers. Established for many years, with good reputation in the industry Storage:Sealed and preserved Application:Fine chemical intermediates, used as the main raw material for

high quality N-[1,1-Bis[(acetyloxy)methyl]-3-(4-octylphenyl)propyl]acetamide

Cas:162358-09-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

high quality N-[1,1-Bis[(acetyloxy)methyl]-3-(4-octylphenyl)propyl]acetamide Application:high quality N-[1,1-Bis[(acetyloxy)methyl]-3-(4-octylphenyl)propyl]acetamide

Guangdong Juda Chemical Industrial Co.,Limited

Factory supply high purity low priceAppearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China

N-[1,1-Bis[(acetyloxy)methyl]-3-(4-octylphenyl)propyl]acetamide CAS No.162358-09-0

Cas:162358-09-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Wuhan Circle Star Chem-medical Technology co.,Ltd.

good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:25kg,50kg,180kg,200kg,250kg,1000kg,customization Application:Pharma;Industry;Agricultural;chemical reaserch Tran

N-[1,1-Bis[(acetyloxy)methyl]-3-(4-octylphenyl)propyl]acetamide

Cas:162358-09-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Synthetic route

2-acetamido-2-[2-(4-octanoylphenyl)ethyl]propane-1,3-diol diacetate
249289-07-4

2-acetamido-2-[2-(4-octanoylphenyl)ethyl]propane-1,3-diol diacetate

2-acetamido-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol diacetate
162358-09-0

2-acetamido-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol diacetate

Conditions
ConditionsYield
With palladium 10% on activated carbon; hydrogen In ethanol at 20℃; for 2h;95%
With palladium 10% on activated carbon; hydrogen In ethanol at 20℃;6.3 g
acetic anhydride
108-24-7

acetic anhydride

N-(1-hydroxy-2-(hydroxymethyl)-4-(4-octylphenyl) butan-2-yl) acetamide
249289-10-9

N-(1-hydroxy-2-(hydroxymethyl)-4-(4-octylphenyl) butan-2-yl) acetamide

2-acetamido-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol diacetate
162358-09-0

2-acetamido-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol diacetate

Conditions
ConditionsYield
With pyridine at 20℃; for 16h; Acetylation;8.25 g
Stage #1: N-(1-hydroxy-2-(hydroxymethyl)-4-(4-octylphenyl) butan-2-yl) acetamide With pyridine
Stage #2: acetic anhydride at 0 - 5℃;
n-octanoic acid chloride
111-64-8

n-octanoic acid chloride

2-acetamido-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol diacetate
162358-09-0

2-acetamido-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol diacetate

Conditions
ConditionsYield
Multi-step reaction with 8 steps
1.1: 43 percent / AlCl3 / 1,2-dichloro-ethane / 3 h / 20 °C
2.1: triethylsilane; TFA / 1,2-dichloro-ethane / 3 h / 20 °C
3.1: 3.40 g / NaOMe; MeOH / 2 h / Heating
4.1: Et3N / CH2Cl2 / 1 h / 20 °C
5.1: 16.0 g / NaI / butan-2-one / 2 h / Heating
6.1: sodium ethoxide / ethanol / 0.5 h / 20 °C
6.2: 61 percent / ethanol / 3 h / 65 °C
7.1: LiAlH4 / tetrahydrofuran / 2 h / 20 °C
8.1: 8.25 g / pyridine / 16 h / 20 °C
View Scheme
Multi-step reaction with 7 steps
1.1: aluminum (III) chloride / 0.01 h / 0.25 - 0.3 °C
1.2: 0 h / 0.2 - 0.5 °C
2.1: sodium hydroxide / water; methanol / 1.5 h / 0.1 - 0.3 °C
3.1: palladium 10% on activated carbon; hydrogen / 0 h / 0.4 °C / Autoclave
4.1: sodium hydroxide / water; methanol / 0.2 - 0.3 °C
5.1: sodium iodide / butanone / 0.67 h / 0.8 - 0.85 °C
6.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 0.45 - 0.5 °C / Inert atmosphere
6.2: 0.4 - 0.45 °C / Inert atmosphere
7.1: calcium chloride / water; isopropyl alcohol / 0 h / 0.2 - 0.3 °C
7.2: 0.01 h / 0 - 0.5 °C
7.3: 0 h / 0.15 - 0.5 °C
View Scheme
Multi-step reaction with 2 steps
1.1: aluminum (III) chloride / 1,2-dichloro-ethane / 1.5 h / -15 - -10 °C / Inert atmosphere
1.2: 19 h / -15 - 20 °C / Inert atmosphere
2.1: palladium 10% on activated carbon; hydrogen / ethanol / 20 °C
View Scheme
acetic acid phenethyl ester
103-45-7

acetic acid phenethyl ester

2-acetamido-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol diacetate
162358-09-0

2-acetamido-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol diacetate

Conditions
ConditionsYield
Multi-step reaction with 8 steps
1.1: 43 percent / AlCl3 / 1,2-dichloro-ethane / 3 h / 20 °C
2.1: triethylsilane; TFA / 1,2-dichloro-ethane / 3 h / 20 °C
3.1: 3.40 g / NaOMe; MeOH / 2 h / Heating
4.1: Et3N / CH2Cl2 / 1 h / 20 °C
5.1: 16.0 g / NaI / butan-2-one / 2 h / Heating
6.1: sodium ethoxide / ethanol / 0.5 h / 20 °C
6.2: 61 percent / ethanol / 3 h / 65 °C
7.1: LiAlH4 / tetrahydrofuran / 2 h / 20 °C
8.1: 8.25 g / pyridine / 16 h / 20 °C
View Scheme
Multi-step reaction with 7 steps
1.1: aluminum (III) chloride / 0.01 h / 0.25 - 0.3 °C
1.2: 0 h / 0.2 - 0.5 °C
2.1: sodium hydroxide / water; methanol / 1.5 h / 0.1 - 0.3 °C
3.1: palladium 10% on activated carbon; hydrogen / 0 h / 0.4 °C / Autoclave
4.1: sodium hydroxide / water; methanol / 0.2 - 0.3 °C
5.1: sodium iodide / butanone / 0.67 h / 0.8 - 0.85 °C
6.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 0.45 - 0.5 °C / Inert atmosphere
6.2: 0.4 - 0.45 °C / Inert atmosphere
7.1: calcium chloride / water; isopropyl alcohol / 0 h / 0.2 - 0.3 °C
7.2: 0.01 h / 0 - 0.5 °C
7.3: 0 h / 0.15 - 0.5 °C
View Scheme
2-acetylaminomalonic acid diethyl ester
1068-90-2

2-acetylaminomalonic acid diethyl ester

(+-)-<2-bromo-ethyl>-phenyl-phosphinic acid ethyl ester

(+-)-<2-bromo-ethyl>-phenyl-phosphinic acid ethyl ester

2-acetamido-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol diacetate
162358-09-0

2-acetamido-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol diacetate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: sodium ethoxide / ethanol / 0.5 h / 20 °C
1.2: 61 percent / ethanol / 3 h / 65 °C
2.1: LiAlH4 / tetrahydrofuran / 2 h / 20 °C
3.1: 8.25 g / pyridine / 16 h / 20 °C
View Scheme
diethyl 2-acetamido-2-[2-(4-octylphenyl)ethyl]malonate
162358-08-9

diethyl 2-acetamido-2-[2-(4-octylphenyl)ethyl]malonate

2-acetamido-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol diacetate
162358-09-0

2-acetamido-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol diacetate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: LiAlH4 / tetrahydrofuran / 2 h / 20 °C
2: 8.25 g / pyridine / 16 h / 20 °C
View Scheme
With pyridine; sodium borohydrid; acetic anhydride In methanol
Multi-step reaction with 2 steps
1.1: calcium acetate / isopropyl alcohol / 0.5 h / 10 - 15 °C
1.2: 10 - 15 °C
2.1: pyridine / 0.08 h
2.2: 0 - 5 °C
View Scheme
Multi-step reaction with 2 steps
1.1: calcium acetate / isopropyl alcohol / 0.5 h / 10 - 15 °C
1.2: 10 - 15 °C
2.1: pyridine
2.2: 0 - 5 °C
View Scheme
2-acetamido-1,3-diacetoxy-2-(2-phenylethyl)propane
162359-95-7

2-acetamido-1,3-diacetoxy-2-(2-phenylethyl)propane

2-acetamido-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol diacetate
162358-09-0

2-acetamido-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol diacetate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: aluminum (III) chloride; 1,2-dichloro-ethane / 18.5 h / 0 - 20 °C
2: palladium 10% on activated carbon; hydrogen / ethanol / 2 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1.1: aluminum (III) chloride / 1,2-dichloro-ethane / 1.5 h / -15 - -10 °C / Inert atmosphere
1.2: 19 h / -15 - 20 °C / Inert atmosphere
2.1: palladium 10% on activated carbon; hydrogen / ethanol / 20 °C
View Scheme
1-phenyl-2-bromoethane
103-63-9

1-phenyl-2-bromoethane

2-acetamido-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol diacetate
162358-09-0

2-acetamido-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol diacetate

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: caesium carbonate / dimethyl sulfoxide / 6 h / 65 °C
2: sodium tetrahydroborate / methanol / 18 h / 0 - 20 °C
3: pyridine / 15 h / 20 °C
4: aluminum (III) chloride; 1,2-dichloro-ethane / 18.5 h / 0 - 20 °C
5: palladium 10% on activated carbon; hydrogen / ethanol / 2 h / 20 °C
View Scheme
4'-(2-hydroxyethyl)octanophenone
219307-07-0

4'-(2-hydroxyethyl)octanophenone

2-acetamido-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol diacetate
162358-09-0

2-acetamido-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol diacetate

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: palladium 10% on activated carbon; hydrogen / 0 h / 0.4 °C / Autoclave
2.1: sodium hydroxide / water; methanol / 0.2 - 0.3 °C
3.1: sodium iodide / butanone / 0.67 h / 0.8 - 0.85 °C
4.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 0.45 - 0.5 °C / Inert atmosphere
4.2: 0.4 - 0.45 °C / Inert atmosphere
5.1: calcium chloride / water; isopropyl alcohol / 0 h / 0.2 - 0.3 °C
5.2: 0.01 h / 0 - 0.5 °C
5.3: 0 h / 0.15 - 0.5 °C
View Scheme
acetic anhydride
108-24-7

acetic anhydride

diethyl 2-acetamido-2-[2-(4-octylphenyl)ethyl]malonate
162358-08-9

diethyl 2-acetamido-2-[2-(4-octylphenyl)ethyl]malonate

2-acetamido-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol diacetate
162358-09-0

2-acetamido-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol diacetate

Conditions
ConditionsYield
Stage #1: diethyl 2-acetamido-2-[2-(4-octylphenyl)ethyl]malonate With calcium chloride In water; isopropyl alcohol at 0.2 - 0.3℃; for 0.00166667h;
Stage #2: With sodium tetrahydroborate In water; isopropyl alcohol at 0 - 0.5℃; for 0.005h;
Stage #3: acetic anhydride With dmap In dichloromethane at 0.15 - 0.5℃; for 0.002h; Solvent; Reagent/catalyst; Temperature;
75 g
acetyl chloride
75-36-5

acetyl chloride

N-(1-hydroxy-2-(hydroxymethyl)-4-(4-octylphenyl) butan-2-yl) acetamide
249289-10-9

N-(1-hydroxy-2-(hydroxymethyl)-4-(4-octylphenyl) butan-2-yl) acetamide

2-acetamido-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol diacetate
162358-09-0

2-acetamido-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol diacetate

Conditions
ConditionsYield
Stage #1: N-(1-hydroxy-2-(hydroxymethyl)-4-(4-octylphenyl) butan-2-yl) acetamide With pyridine for 0.0833333h;
Stage #2: acetyl chloride at 0 - 5℃;
2-acetamido-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol diacetate
162358-09-0

2-acetamido-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol diacetate

fingolimod hydrochloride

fingolimod hydrochloride

Conditions
ConditionsYield
Stage #1: 2-acetamido-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol diacetate With methanol; water; lithium hydroxide Reflux;
Stage #2: With hydrogenchloride In water; ethyl acetate; isopropyl alcohol at 50 - 70℃; for 0.5h;
86.03%
With hydrogenchloride In water at 100℃; for 1h;79%
Multi-step reaction with 2 steps
1: sodium hydroxide / water; methanol / 2 h / Reflux
2: hydrogenchloride / water; methanol / 0.5 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: lithium hydroxide / methanol / 2 h / Reflux
2: hydrogenchloride / isopropyl alcohol; ethyl acetate / 1 h / 70 - 80 °C
View Scheme
2-acetamido-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol diacetate
162358-09-0

2-acetamido-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol diacetate

fingolimod
162359-55-9

fingolimod

Conditions
ConditionsYield
With lithium hydroxide In methanol for 2h; Hydrolysis; Heating;
With sodium hydroxide In methanol; water for 2h; Reagent/catalyst; Reflux;70 g
With lithium hydroxide In methanol for 2h; Reflux;
2-acetamido-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol diacetate
162358-09-0

2-acetamido-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol diacetate

A

acetic acid 2-acetoxymethyl-2-acetylamino-4-(3-bromo-4-octylphenyl)butyl ester
851039-26-4

acetic acid 2-acetoxymethyl-2-acetylamino-4-(3-bromo-4-octylphenyl)butyl ester

B

acetic acid 2-acetoxymethyl-2-acetylamino-4-(2-bromo-4-octylphenyl)butyl ester
851039-28-6

acetic acid 2-acetoxymethyl-2-acetylamino-4-(2-bromo-4-octylphenyl)butyl ester

Conditions
ConditionsYield
With N-Bromosuccinimide In acetic acid at 20℃; for 730.5h;
2-acetamido-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol diacetate
162358-09-0

2-acetamido-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol diacetate

C25H38FNO5
1609282-73-6

C25H38FNO5

Conditions
ConditionsYield
With (S,S)-chloro[2,2'-[1,2-cyclohexanediylbis(nitrilomethylidyne)]bis-[4,6-bis(1,1-dimethylethyl)phenolato]](2-)-N,N',O,O'-manganese; iodosylbenzene; triethylamine tris(hydrogen fluoride) In acetonitrile at 50℃; Schlenk technique; Inert atmosphere;
2-acetamido-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol diacetate
162358-09-0

2-acetamido-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol diacetate

C25H38(18)FNO5
1609282-63-4

C25H38(18)FNO5

Conditions
ConditionsYield
Stage #1: 2-acetamido-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol diacetate With (R,R)-Mn(salen)OTs; potassium carbonate In water; acetone at 20℃; for 0.0166667h;
Stage #2: With iodosylbenzene In water; acetone at 50℃; for 0.166667h; regioselective reaction;

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