Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities
Cas:1839-18-5
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiryWelcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
Cas:1839-18-5
Min.Order:1 Metric Ton
Negotiable
Type:Manufacturers
inquiryItems Standard Result Assay (Ursolic acid) 98%min 98.22% ----------------------------------------------------------------
Cas:1839-18-5
Min.Order:1 Gram
FOB Price: $100.0 / 500.0
Type:Trading Company
inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Cas:1839-18-5
Min.Order:5 Kiloliter
FOB Price: $1.2 / 5.0
Type:Manufacturers
inquiry2-Chloroadenine Basic information Product Name: 2-Chloroadenine Synonyms: 2-CHLOROADENINE;2-CHLORO-9H-PURIN-6-AMINE;2-CHLORO-6-AMINOPURINE;6-Amino-2-chloro-7H-purine;2-Chlorophenthiazine
Cas:1839-18-5
Min.Order:1 Metric Ton
Negotiable
Type:Lab/Research institutions
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:1839-18-5
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiryOur Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con
Cas:1839-18-5
Min.Order:1 Kilogram
FOB Price: $15.0 / 50.0
Type:Trading Company
inquiry1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:powder Storage:Store in sealed containers at cool & dry pla
Cas:1839-18-5
Min.Order:100 Gram
Negotiable
Type:Other
inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:1839-18-5
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryAdvantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the
Cas:1839-18-5
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryOur company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present
Cas:1839-18-5
Min.Order:1 Kilogram
FOB Price: $1065.0 / 1177.4
Type:Trading Company
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:1839-18-5
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryPRODUCT DETAILS
Cas:1839-18-5
Min.Order:500 Kilogram
FOB Price: $1.0 / 2.0
Type:Lab/Research institutions
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Cas:1839-18-5
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryBest quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia
Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments
Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
Cas:1839-18-5
Min.Order:0 Metric Ton
Negotiable
Type:Lab/Research institutions
inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
2-ChloroadenineAppearance:Pls see the Details Storage:Keep away of light, hot, water, Store in dry, dark and ventilated place Package:according to customers' requirements Application:Steroids, Cosmetics Ingredients, APIs, Intermediates, OLED&Battery
Product name: 2-Chloroadenine CAS No.:1839-18-5 Molecule Formula:C5H4ClN5 Molecule Weight:169.57 Purity: 98.0% Package: 25kg/drum Description:Light yellow powder Manufacture Standards:Enterprise Standard TESTING IT
Cas:1839-18-5
Min.Order:1 Kilogram
Negotiable
Type:Trading Company
inquiryGMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,
2-Chloroadenine Basic information Product Name: 2-Chloroadenine Synonyms: 2-CHLOROADENINE;2-CHLORO-9H-PURIN-6-AMINE;2-CHLORO-6-AMINOPURINE;6-Amino-2-chloro-7H-purine;Cladribine EP Impurity C;Regadenoson impurity H;2-Chlorophenthiazine;2-chloro
HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture. With about ten years of business experiences on the marketing & distribution, thinkchem specializes in exp
We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O
1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer
Cas:1839-18-5
Min.Order:1 Metric Ton
FOB Price: $7.0 / 8.0
Type:Trading Company
inquiryWuhu Nuovo Chemical Technology Co., Ltd. was established in August 2014, mainly engaged in the development, production and sales of ionic liquids, ribose, nucleosides, nucleotides and related chemicals; Products are mainly used in new energy, new ma
Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea
Product Name: 2-Chloroadenine Synonyms: 2-CHLOROADENINE;2-CHLORO-9H-PURIN-6-AMINE;2-CHLORO-6-AMINOPURINE;6-Amino-2-chloro-7H-purine;2-Chlorophenthiaz…Appearance:Solid powder Storage:Sealed,light and oxygen resistant Package:aluminum foil bag,carton
SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in custom synthe
Conditions | Yield |
---|---|
With ammonia In methanol at 100℃; for 12h; | 100% |
With ammonia In methanol at 100℃; for 16h; | 97% |
With ammonia In methanol at 160℃; for 24h; | 95% |
Conditions | Yield |
---|---|
With ammonia In isopropyl alcohol at 120℃; | 100% |
2,6 dichloropurine
A
4-cyano-5-(cyanoamino)imidazole
B
2-chloroadenine
C
2,6-diaminopurine
Conditions | Yield |
---|---|
With potassium amide In ammonia at -33℃; for 20h; | A 25% B 12% C 13% |
2-Chloro-5'-O-(4,4'-dimethoxytrityl)-2',3'-O-thiocarbonyladenosine
A
2-chloroadenine
B
(2R,3R,5S)-2-(6-amino-2-chloro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3-ol
C
9-{(3aR,4R,6R,6aR)-6-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl}-2-chloro-9H-purin-6-ylamine
Conditions | Yield |
---|---|
With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; acetic acid 1) toluene, 110-120 deg C, 3.5 h, 2) 50 deg C, 30 min; Yield given. Multistep reaction; |
2-Chloro-9-(2-deoxy-β-L-erythro-pentofuranosyl)adenine
A
2-chloroadenine
Conditions | Yield |
---|---|
With E. coli purine nucleoside phosphorylase Enzyme kinetics; Substitution; |
2-chloro-9-(2-deoxy-β-L-erythro-pentofuranosyl)adenine
A
2-chloroadenine
Conditions | Yield |
---|---|
With E. coli purine nucleoside phosphorylase Enzyme kinetics; Substitution; |
clofarabine
A
2-chloroadenine
B
2-deoxy-2-fluoro-α-D-arabinofuranose 1-phosphate
Conditions | Yield |
---|---|
With E. coli purine nucleoside phosphorylase Enzyme kinetics; Substitution; |
2-chloro-2'-deoxyadenosine
A
2-deoxy–α-D-ribose 1-phosphate
B
2-chloroadenine
Conditions | Yield |
---|---|
With E. coli purine nucleoside phosphorylase Enzyme kinetics; Substitution; |
Conditions | Yield |
---|---|
With acetic acid In water pH=2.3; Hydrolysis; |
A
2-chloroadenine
Conditions | Yield |
---|---|
With E. coli purine nucleoside phosphorylase Enzyme kinetics; Substitution; |
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 69 percent / pyridine / 24 h / Ambient temperature 2: 80 percent / acetonitrile / Ambient temperature 3: 1) AIBN, n-Bu3SnH, 2) aq.AcOH / 1) toluene, 110-120 deg C, 3.5 h, 2) 50 deg C, 30 min View Scheme | |
adenosine phosphorilase In water pH=7.4; Enzymatic reaction; Phosphate buffer; |
6-amino-2-chloro-9-(5'-deoxy-β-D-ribofuranosyl)-9H-purine
2-chloroadenine
Conditions | Yield |
---|---|
adenosine phosphorilase In water pH=7.4; Enzymatic reaction; Phosphate buffer; |
2-chloroadenine
Conditions | Yield |
---|---|
With ammonia In methanol |
Conditions | Yield |
---|---|
With ammonia In methanol |
Conditions | Yield |
---|---|
With potassium dihydrogenphosphate; E-purine nucleoside phosphorylase-0002 In aq. buffer at 40℃; for 0.3h; pH=9; Equilibrium constant; Thermodynamic data; Reagent/catalyst; Temperature; pH-value; Enzymatic reaction; |
Conditions | Yield |
---|---|
With potassium dihydrogenphosphate; E-purine nucleoside phosphorylase-0002 In aq. buffer at 40℃; for 0.3h; pH=9; Equilibrium constant; Thermodynamic data; Reagent/catalyst; Temperature; pH-value; Enzymatic reaction; |
2-chloroadenine
4-cyanobenzyl bromide
4-((6-amino-2-chloro-9H-purin-9-yl)methyl)benzonitrile
Conditions | Yield |
---|---|
Stage #1: 2-chloroadenine With potassium carbonate In dimethyl sulfoxide for 0.0833333h; Stage #2: 4-cyanobenzyl bromide In dimethyl sulfoxide at 20℃; for 22h; | 96% |
Conditions | Yield |
---|---|
Stage #1: 2-chloroadenine With potassium carbonate In dimethyl sulfoxide for 0.0333333h; Stage #2: 1-bromomethyl-4-iodobenzene In dimethyl sulfoxide at 20℃; for 19h; | 95% |
Conditions | Yield |
---|---|
Stage #1: 2-chloroadenine With potassium carbonate In dimethyl sulfoxide for 0.0333333h; Stage #2: benzyl bromide In dimethyl sulfoxide at 20℃; for 30h; | 94% |
With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 25℃; Inert atmosphere; | 67% |
With potassium carbonate In N,N-dimethyl-formamide | 58% |
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 4h; | 44% |
Conditions | Yield |
---|---|
In water at 180℃; for 1h; | 92% |
at 18℃; for 18h; Autoclave; | 86% |
In water at 180℃; for 18h; Autoclave; | 86% |
Conditions | Yield |
---|---|
With triethylamine In butan-1-ol at 90℃; for 4h; | 92% |
Conditions | Yield |
---|---|
With caesium carbonate; palladium diacetate In water; acetonitrile at 150℃; for 0.0833333h; Suzuki-Miyaura cross-coupling reaction; microwave irradiation; | 90% |
methyl 1,2,3-tri-O-acetyl-β-D-ribofuronate
2-chloroadenine
methyl 1-[2-chloroadenin-9-yl]-2,3-di-O-acetyl-β-D-ribofuronate
Conditions | Yield |
---|---|
Stage #1: 2-chloroadenine With ammonium sulfate; 1,1,1,3,3,3-hexamethyl-disilazane In acetonitrile for 16h; Heating; Stage #2: methyl 1,2,3-tri-O-acetyl-β-D-ribofuronate With trimethylsilyl trifluoromethanesulfonate In 1,2-dichloro-ethane at 90℃; for 0.333333h; microwave irradiation; Further stages.; | 89% |
Conditions | Yield |
---|---|
With magnesium hydroxide; purine nucleoside phosphorylase In water at 45℃; | 88% |
2-chloroadenine
3-methoxycarbonylbenzyl bromide
Methyl 3-((6-amino-2-chloro-9H-purin-9-yl)methyl)benzoate
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 60℃; for 1.5h; | 86% |
1-chloro-2-(chloromethyl)benzene
2-chloroadenine
2-chloro-9-(2-chlorobenzyl)adenine
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 75℃; for 4h; | 85% |
2-chloroadenine
Acetic acid (3R,4S,5S)-2-acetoxy-4-benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-5-(toluene-4-sulfonyloxymethyl)-tetrahydro-furan-3-yl ester
(2R,3R,4S,5S)-2-(6-amino-2-chloro-9H-purin-9-yl)-4-(benzyloxy)-5-((tert-butyldiphenylsilyloxy)methyl)-5-(tosyloxymethyl)tetrahydrofuran-3-yl acetate
Conditions | Yield |
---|---|
Stage #1: 2-chloroadenine; Acetic acid (3R,4S,5S)-2-acetoxy-4-benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-5-(toluene-4-sulfonyloxymethyl)-tetrahydro-furan-3-yl ester With N,O-bis-(trimethylsilyl)-acetamide In acetonitrile at 65℃; for 1.5h; Inert atmosphere; Stage #2: With trimethylsilyl trifluoromethanesulfonate In acetonitrile at 0 - 65℃; for 3h; Vorbrüggen coupling; Inert atmosphere; Stage #3: With sodium hydrogencarbonate In water; acetonitrile Inert atmosphere; | 85% |
Conditions | Yield |
---|---|
With hydrogenchloride; potassium dihydrogenphosphate; potassium hydroxide In water; dimethyl sulfoxide at 58 - 61℃; for 4h; pH=7.1-7.2; Enzymatic reaction; | 85% |
With potassium phosphate; Geobacillus thermoglucosidasius purine nucleoside phosphorylase; Thermus thermophilus pyrimidine nucleoside phosphorylase In water at 70℃; for 1h; pH=7; Enzymatic reaction; | |
With dipotassium hydrogenphosphate; purine nucleoside phosphorylase; pyrimidine nucleoside phosphorylase; glycine In aq. buffer at 60℃; pH=9; Equilibrium constant; Enzymatic reaction; |
Conditions | Yield |
---|---|
With 1A cells; E. coli BMT 4D In phosphate buffer at 65℃; for 4h; pH=7.5; | 81% |
With purine nucleoside 2’-deoxyribosyltransferase from Trypanosoma brucei immobilized on glutaraldehyde-activated MagReSynAmine microspheres In aq. phosphate buffer at 50℃; for 0.333333h; pH=6; Enzymatic reaction; |
1-β-D-ribofuranosyl-1H-benzotriazole
2-chloroadenine
2',3',5'-tri-O-acetyl-2-chloroadenosine
Conditions | Yield |
---|---|
With tin(IV) chloride In nitromethane at 20℃; for 3h; Solvent; Cooling with ice; | 81% |
4-(hydroxymethyl)benzyl chloride
2-chloroadenine
2-chloro-9-(4-hydroxymethylbenzyl)adenine
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 24h; | 80% |
Conditions | Yield |
---|---|
With caesium carbonate In N,N-dimethyl-formamide at 70℃; | 80% |
Conditions | Yield |
---|---|
With sodium hydroxide In water at 100℃; for 0.166667h; Microwave irradiation; regioselective reaction; | 79% |
Conditions | Yield |
---|---|
With triethylamine In water at 100℃; for 0.0833333h; Michael addition; microwave irradiation; | 77% |
2-chloroadenine
2-nitrophenylmethyl bromide
2-chloro-9-(2-nitrobenzyl)-9H-purin-6-ylamine
Conditions | Yield |
---|---|
Stage #1: 2-chloroadenine With sodium hydride In N,N-dimethyl-formamide at 20℃; for 3h; Inert atmosphere; Stage #2: 2-nitrophenylmethyl bromide In N,N-dimethyl-formamide at 20℃; for 72h; Inert atmosphere; | 77% |
2-chloroadenine
diisopropyl 2-(chloroethoxy)methylphosphonate
6-amino-2-chloro-9-{2-[(diisopropoxyphosphoryl)methoxy]ethyl}-9H-purine
Conditions | Yield |
---|---|
With caesium carbonate In N,N-dimethyl-formamide at 120℃; for 16h; | 76.5% |
Conditions | Yield |
---|---|
for 9h; Heating / reflux; | 76% |
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide Ambient temperature; | 75% |
Conditions | Yield |
---|---|
With sodium at 140℃; for 10h; | 75% |
With potassium tert-butylate In tetrahydrofuran at 170℃; for 0.666667h; Microwave irradiation; | 70% |
With potassium tert-butylate In tetrahydrofuran at 170℃; for 0.666667h; Microwave irradiation; | 70% |
2-deoxy-2-fluoro-3,5-di-O-benzoyl-α-D-arabinofuranosyl bromide
2-chloroadenine
6-amino-2-chloro-9-(2'-deoxy-2'-fluoro-3',5'-di-O-benzoyl-β-D-arabinofuranosyl)-9H-purine
Conditions | Yield |
---|---|
Stage #1: 2-chloroadenine With calcium hydride In acetonitrile; tert-butyl alcohol at 53℃; for 2.5h; Stage #2: 2-deoxy-2-fluoro-3,5-di-O-benzoyl-α-D-arabinofuranosyl bromide In dichloromethane; acetonitrile; tert-butyl alcohol at 50℃; for 3h; Solvent; Temperature; Reagent/catalyst; | 75% |
With potassium tert-butylate In tert-Amyl alcohol; 1,2-dichloro-ethane; acetonitrile at 50℃; for 19h; Inert atmosphere; | 50% |
With 1,8-diazabicyclo[5.4.0]undec-7-ene In CHCl3/MeOH; chloroform; acetonitrile | 16 mg (28%) |
Conditions | Yield |
---|---|
Stage #1: sodium methylate; 2-chloroadenine In methanol at 100℃; for 24h; Stage #2: With hydrogenchloride In methanol; water at 20 - 60℃; for 17h; pH=9.5; | 73% |
In methanol at 100℃; for 24h; Sealed vessel; | 70% |
α-D-2′-deoxyribofuranose-1-O-phosphate bis(cyclohexylammonium) salt
2-chloroadenine
2-chloro-2'-deoxyadenosine
Conditions | Yield |
---|---|
With purine nucleoside phosphorylase; calcium hydroxide at 45℃; for 48h; pH=9.3; Enzymatic reaction; | 72% |
Conditions | Yield |
---|---|
In dimethyl sulfoxide; butan-1-ol at 170℃; for 1.5h; Microwave irradiation; | 71% |
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 16h; | 70% |
With sodium hydroxide; Aliquat 336 In hexane for 8h; Heating; | 27% |
Stage #1: 2-chloroadenine With potassium carbonate In N,N-dimethyl-formamide at 50℃; for 1h; Stage #2: benzyl chloride In N,N-dimethyl-formamide at 90℃; for 18h; | 25% |
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