Clotrimazole[CAS:23593-75-1] USP36 HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture. With about ten years of business experiences on the marketing & distribut
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Strict quality control: good raw materials, good quality, Zenuo Biology has always regarded quality as the life of the enterprise. Zenuo Biology has an independent quality control department and long-term cooperation with the third-party detect
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inquiryDayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe
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inquiryWhy is SINOWAY: 1) Specialized in pharmaceutical and healthcare industrial for 34 years. 2) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days. 4) We have warehouse in USA with quickly shipment . 5) We c
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inquiryItems Standard Result Assay 98%min -----------------------------------------------------------------------------------------------
Cas:23593-75-1
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inquiryWelcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
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inquiryhebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm
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inquiryUnique advantages for Clotrimazole Cas23593-75-1 Guaranteed the purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White to pale yellow,crystalline powder Storage:Store at RT Package:25kg/drum Ap
Cas:23593-75-1
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23593-75-1 - Physico-chemical Properties Molecular Formula C22H17ClN2 Molar Mass 344.84 Density 1.1095 (rough estimate) Melting Point 147-149°C Boling Point 501.14°C (rough estimate
Cas:23593-75-1
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Name:Lotrimin CAS NO:23593-75-1 Grade:Medical, scientific research, export Product Quality 12 years of chemical raw materials Mature operation of the industry System stability Data storage Security without vulnerability Product Technology
Cas:23593-75-1
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inquiryStock products, own laboratory Appearance:White to Almost white neat Storage:2-8°C Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:shanghai
Cas:23593-75-1
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Cas:23593-75-1
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inquiryClotrimazole Basic information Broad-spectrum antifungal drug Pharmacokinetics Clinical application Mechanism Drug Interactions Adverse reactions Administration instructions Chemical Properties Production method
Cas:23593-75-1
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inquiryMOQ: 1kg Form: Powder Colour: White Test: HPLC Function: anti antiviral Grade: Pharm Appearance:white Storage:room Package:drum Application:anti antiviral Port:S
Cas:23593-75-1
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inquiryName: Clotrimazole crystalline Synonyms: (2-Chlorophenyl)diphenyl-1-imidazolylmethane CAS:23593-75-1 MF: C22H17ClN2 Appearance: white powder Storage:Store in cool and dry place, away from sun light. Package: 25kgs/drum Application:APIs Tra
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inquiryAppearance:White to pale yellow crystalline powder Storage:ln stock Package:25kg/Barrel Application:Chemicals Transportation:Express/Sea/Air Port:Any port in china
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Cas:23593-75-1
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Cas:23593-75-1
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inquiry1H-imidazole
diphenyl phosphite
o-chlorotriphenylmethanol
4-methyl-2-pentanone
clotrimazole
Conditions | Yield |
---|---|
With sodium hydroxide | 100% |
With sodium hydroxide | 77% |
Conditions | Yield |
---|---|
With sodium carbonate at 25℃; for 48h; Reagent/catalyst; Solvent; Concentration; Green chemistry; | 92% |
With sodium carbonate at 20℃; for 48h; Sealed tube; | 92% |
With triethylamine In acetonitrile Heating; | |
With triethylamine In toluene at 20 - 50℃; for 3h; Temperature; Solvent; Inert atmosphere; |
1H-imidazole
diphenyl phosphite
o-chlorotriphenylmethanol
clotrimazole
Conditions | Yield |
---|---|
In toluene | 74.5% |
In acetonitrile; benzene | 73% |
o-chlorotriphenylmethanol
clotrimazole
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: thionyl chloride / Heating 2: triethylamine / acetonitrile / Heating View Scheme |
clotrimazole
4-((1,3-bis(dodecanoyloxy)propan-2-yl)oxy)-4-oxobutanoic acid
Conditions | Yield |
---|---|
In acetonitrile at 50℃; for 6h; | 100% |
clotrimazole
o-chlorotriphenylmethanol
Conditions | Yield |
---|---|
With hydrogenchloride for 2h; Heating; | 93% |
With hydrogenchloride; water for 3h; Heating / reflux; | 85% |
With hydrogenchloride In water; isopropyl alcohol for 17h; Heating; | 36% |
potassium hexafluorophosphate
clotrimazole
Conditions | Yield |
---|---|
Stage #1: potassium hexafluorophosphate; cis-{Ru(Bipy)(Dppe)Cl2} In dichloromethane for 1h; Inert atmosphere; Stage #2: clotrimazole In dichloromethane for 6h; Reflux; Inert atmosphere; | 92% |
clotrimazole
Conditions | Yield |
---|---|
With deuteromethanol; di(tertbutyl)phenylphosphine; silver carbonate at 65℃; for 48h; Inert atmosphere; | 91% |
clotrimazole
1-bromomethyl-3,5-difluoro-benzene
Conditions | Yield |
---|---|
In ethyl acetate for 48h; Heating; | 90% |
potassium hexafluorophosphate
dichloro[1,4-bis(diphenylphosphino)butane](2,2'-bipyridine)ruthenium(II)
clotrimazole
Conditions | Yield |
---|---|
Stage #1: potassium hexafluorophosphate; dichloro[1,4-bis(diphenylphosphino)butane](2,2'-bipyridine)ruthenium(II) In dichloromethane for 1h; Inert atmosphere; Stage #2: clotrimazole In dichloromethane for 6h; Reflux; Inert atmosphere; | 90% |
[dichloro(p-cymene)(triphenylphosphane)ruthenium(II)]
clotrimazole
Conditions | Yield |
---|---|
In methanol for 8h; Reflux; Inert atmosphere; | 90% |
Conditions | Yield |
---|---|
In methanol at 25℃; for 24h; | 90% |
Conditions | Yield |
---|---|
In methanol; chloroform for 5h; Reflux; | 89% |
silver(I) hexafluorophosphate
clotrimazole
Conditions | Yield |
---|---|
In methanol; chloroform for 3h; Reflux; | 86% |
potassium hexafluorophosphate
clotrimazole
Conditions | Yield |
---|---|
Stage #1: potassium hexafluorophosphate; cis-[RuCl2(1,1′-bis(diphenylphosphino)ferrocene)(2,2′-bipyridine)] In dichloromethane for 1h; Inert atmosphere; Stage #2: clotrimazole In dichloromethane for 6h; Reflux; Inert atmosphere; | 86% |
Conditions | Yield |
---|---|
In methanol at 25℃; for 24h; | 84% |
clotrimazole
triphenylmethane
Conditions | Yield |
---|---|
With tetraethylammonium perchlorate; triethylamine In dimethyl sulfoxide at 20℃; for 24h; Electrolysis; Green chemistry; | 81% |
di-μ-chloro-bis(1,5-cyclooctadiene)dirhodium
clotrimazole
RhCl(1,5-cyclooctadiene)(1-[(2-chlorophenyl)diphenylmethyl]-1H-imidazole)
Conditions | Yield |
---|---|
In ethanol N2-atmosphere; stoich. amts., stirring at room temp. for 1 h; collection (filtration), washing (MeOH), drying (vac.); elem. anal.; | 80% |
clotrimazole
4-chloro-1-((2-chlorophenyl)diphenylmethyl)-1H-imidazole
Conditions | Yield |
---|---|
With N-chloro-N-fluoro-benzenesulfonamide In acetonitrile at 20℃; Reagent/catalyst; | 80% |
With N-chloro-N-fluoro-benzenesulfonamide In acetonitrile at 20℃; regioselective reaction; | 77% |
With 2-chloro-1,3-bis(methoxycarbonyl)guanidine In chloroform at 20℃; for 12h; Solvent; regioselective reaction; | 72% |
clotrimazole
(bromomethylcyclohexane)
Conditions | Yield |
---|---|
In ethyl acetate for 48h; Heating; | 79% |
bis(triphenylphosphino)copper(I) nitrate
clotrimazole
Conditions | Yield |
---|---|
In acetonitrile for 24h; | 79% |
Conditions | Yield |
---|---|
With 2,3-dicyano-5,6-dichloro-p-benzoquinone In 1,2-dimethoxyethane at 20℃; for 5h; Inert atmosphere; Schlenk technique; | 78% |
Conditions | Yield |
---|---|
In ethanol; water hot soln. (60 °C) of metal chloride added to hot soln. (60 °C) of CLMZ, mixt. stirred under reflux for 1 h; pptn., filtration, washing (ethanol/water, petroleum ether), elem. anal.; | 77% |
clotrimazole
Conditions | Yield |
---|---|
With N-chloro-N-fluoro-benzenesulfonamide; potassium bromide In acetonitrile at 20℃; for 0.25h; | 77% |
clotrimazole
methyl iodide
Conditions | Yield |
---|---|
In dichloromethane at 45℃; for 0.25h; Microwave irradiation; | 75% |
In ethyl acetate at 20℃; for 48h; | 49% |
tetrakis(actonitrile)copper(I) hexafluorophosphate
clotrimazole
Conditions | Yield |
---|---|
In dichloromethane stoich. amts., room temp., 24 h; vol. reduction (N2-stream), Et2O addn., cooling to -5°C (pptn.), collection (filtration), washing (Et2O), drying (vac.); elem. anal.; | 75% |
Conditions | Yield |
---|---|
In ethanol; water hot soln. (60 °C) of metal chloride added to hot soln. (60 °C) of CLMZ, mixt. stirred under reflux for 1 h; pptn., filtration, washing (ethanol/water, petroleum ether), elem. anal.; | 75% |
Conditions | Yield |
---|---|
In methanol; chloroform at 20℃; for 0.075h; Reflux; | 75% |
Conditions | Yield |
---|---|
In methanol at 25℃; for 0.5h; | 74% |
clotrimazole
Conditions | Yield |
---|---|
With water-d2; potassium carbonate; silver carbonate; cyclohexyldiphenylphosphine In toluene at 120℃; for 12h; | 73% |
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