Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities
Cas:2457-80-9
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiry1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
Cas:2457-80-9
Min.Order:1 Gram
FOB Price: $0.1
Type:Manufacturers
inquiryWith our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin
Cas:2457-80-9
Min.Order:1 Kilogram
FOB Price: $2.0 / 5.0
Type:Trading Company
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:2457-80-9
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiry1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ
Cas:2457-80-9
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiry5'-DEOXY-5'-METHYLTHIOADENOSINE CAS:2457-80-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high qu
Cas:2457-80-9
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:2457-80-9
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryNewCan Biotech Limited was established in 2021 and is primarily engaged in the research, development, production, and sales of sugars, nucleosides, nucleotides, phosphorylated monomers, as well as next-generation antiviral and antitumor drug intermed
Cas:2457-80-9
Min.Order:1 Milligram
Negotiable
Type:Trading Company
inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Cas:2457-80-9
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:2457-80-9
Min.Order:10 Gram
FOB Price: $100.0
Type:Lab/Research institutions
inquiry1)quick response within 12 hours; 2)quality guarantee: all products are strictly tested by our qc, confirmed by qa and approved by third party lab in china, usa, canada, germany, uk, italy, france etc. 3) oem/odm available; 4) rea
Cas:2457-80-9
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiryGMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,
5'-DEOXY-5'-METHYLTHIOADENOSINE Basic information Product Name: 5'-DEOXY-5'-METHYLTHIOADENOSINE Synonyms: 2-(6-aminopurin-9-yl)-5-(methylsulfanylmethyl)oxolane-3,4-diol;7-(5-Methylthio-5-deoxy-D-ribofuranosyl)-7H-purine-6-amine;
Cas:2457-80-9
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryOur advantage:Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientif
Cas:2457-80-9
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryLower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe
Cas:2457-80-9
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryAcmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea
Cas:2457-80-9
Min.Order:1 bottle
Negotiable
Type:Lab/Research institutions
inquiryhigh quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea
Hunan chemfish Pharmaceutical co.,Ltd a comprehensive enterprise, is located in High-Tech Science Park,Changsha,Chia . Specializing in R&D, manufacture and marketing, we provide a wide range of products and the most professional services to meet the
Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali
Cas:2457-80-9
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryGMP factory Packing with pallet as buyer's special request Best service after shipment with e-mail Cargos together with container sales seervice available Api, inhibitor, and fine chemicals for more than 6 years. Application:
Cas:2457-80-9
Min.Order:0 Metric Ton
Negotiable
Type:Trading Company
inquiryWe product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Application:Chemical intermediate
Cas:2457-80-9
Min.Order:0
Negotiable
Type:Trading Company
inquiryFactory supply high purity low priceAppearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China
Adenosine,5'-S-methyl-5'-thio- cas 2457-80-9Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express
Cas:2457-80-9
Min.Order:0
Negotiable
Type:Other
inquiryfactory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
Cas:2457-80-9
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiry2457-80-9 Application:intermediate
Cas:2457-80-9
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquirygood quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:5mg Application:Pharma;Industry;Agricultural;chemical reaserch Transportation:by express or by sea Port:Any port
Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen
Provide HPLC,HNMR,MS and COA. Package:Glass bottles Application:scientific research Transportation:by air
Cas:2457-80-9
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryConditions | Yield |
---|---|
With sodium hydride In N,N-dimethyl-formamide -30 deg C to r.t., overnight; | 86% |
With sodium hydroxide In methanol; water at 75℃; for 24h; | 75% |
With sodium hydride In N,N-dimethyl-formamide | |
With potassium tert-butylate In tetrahydrofuran; N,N-dimethyl-formamide at 40℃; for 12h; |
5'-deoxy-5'-chloroadenosine
sodium thiomethoxide
5'-Deoxy-5'-methylthioadenosine
Conditions | Yield |
---|---|
In water at 75℃; for 24h; | 65% |
In N,N-dimethyl-formamide at 20℃; | 50% |
Conditions | Yield |
---|---|
With tributylphosphine In N,N-dimethyl-formamide for 240h; | 38% |
9-((3aR,4R,6S,6aS)-2,2-dimethyl-6-((methylthio)methyl)tetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-9H-purin-6-amine
5'-Deoxy-5'-methylthioadenosine
Conditions | Yield |
---|---|
With sulfuric acid | |
With sulfuric acid; acetone | |
With sulfuric acid; acetic acid |
2',3'-Di-O-acetyl-5'-deoxy-5'-(methylthio)adenosine sulfoxide
A
5'-Deoxy-5'-methylthioadenosine
B
5'-Deoxy-5'-<(monofluoromethyl)thio>adenosine
Conditions | Yield |
---|---|
With dimethylaminosulphur trifluoride; ammonia 1) CHCl3, 55 deg C, 2.5-3 h, 2) MeOH, r.t., 2.5 h; Yield given. Multistep reaction. Yields of byproduct given; |
[(2S,3S,4R,5R)-5-(6-Amino-purin-9-yl)-3,4-dihydroxy-tetrahydro-furan-2-ylmethyl]-[3-(2-hydroxy-phenyl)-3-methyl-butyl]-methyl-sulfonium
A
4,4-dimethylchromane
B
5'-Deoxy-5'-methylthioadenosine
Conditions | Yield |
---|---|
With acetate buffer In water at 40℃; pH 4 to 10; | |
With acetate buffer In water at 40℃; Mechanism; other oxyanion buffers; amine buffers; |
[(2S,3S,4R,5R)-5-(6-Amino-purin-9-yl)-3,4-dihydroxy-tetrahydro-furan-2-ylmethyl]-[3-(2-hydroxy-phenyl)-3-methyl-butyl]-methyl-sulfonium
A
5'-Deoxy-5'-methylthioadenosine
Conditions | Yield |
---|---|
With amine buffer In water at 40℃; pH > 10; |
5'-Deoxy-5'-methylthioadenosine
Conditions | Yield |
---|---|
With extractene from cultures of yeast | |
With aerobacter aerogenes |
A
5'-Deoxy-5'-methylthioadenosine
Conditions | Yield |
---|---|
With water pH 4-6; |
5'-chloro-5'-deoxy-2',3'-O-sulfinyladenosine
5'-Deoxy-5'-methylthioadenosine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 98 percent / water; methanol / 20 °C 2: 50 percent / dimethylformamide / 20 °C View Scheme | |
Multi-step reaction with 2 steps 1: conc. aq. NH4OH / methanol / 1 h / Ambient temperature 2: 75 percent / NaOH / H2O; methanol / 24 h / 75 °C View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 2: acetate buffer / H2O / 40 °C / other oxyanion buffers; amine buffers View Scheme | |
Multi-step reaction with 2 steps 2: amine buffer / H2O / 40 °C / pH > 10 View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 74 percent / 4-(dimethylamino)pyridine, Et3N / acetonitrile / 1 h 2: 1) (dimethylamino)sulfur trifluoride, 2) NH3 / 1) CHCl3, 55 deg C, 2.5-3 h, 2) MeOH, r.t., 2.5 h View Scheme |
5'-chloro-5'-deoxy-2',3'-O-sulphinyladenosine hydrochloride
5'-Deoxy-5'-methylthioadenosine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 94 percent / conc.NH4OH / methanol; H2O / 0.5 h / Ambient temperature 2: 86 percent / NaH / dimethylformamide / -30 deg C to r.t., overnight View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 1.) SOCl2, pyridine, 2.) NH3 / 1.) acetonitrile, 2.) MeOH, H2O 2: NaH / dimethylformamide View Scheme | |
Multi-step reaction with 4 steps 1: unter Zusatz von ZnCl2 2: pyridine 3: DMF 4: aqueous H2SO4; acetic acid View Scheme | |
Multi-step reaction with 4 steps 1: unter Zusatz von ZnCl2 2: pyridine 3: acetone 4: aqueous H2SO4 View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: pyridine 2: DMF 3: aqueous H2SO4; acetic acid View Scheme | |
Multi-step reaction with 3 steps 1: pyridine 2: acetone 3: aqueous H2SO4 View Scheme |
((3aR,4R,6R,6aR)-6-(6-amino-9H-purin-9-yl)-2,2-dimethyl-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl 4-methylbenzenesulfonate
5'-Deoxy-5'-methylthioadenosine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: DMF 2: aqueous H2SO4; acetic acid View Scheme | |
Multi-step reaction with 2 steps 1: acetone; dioxane 2: aqueous H2SO4; acetone View Scheme | |
Multi-step reaction with 2 steps 1: acetone 2: aqueous H2SO4 View Scheme |
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide at 20℃; for 48h; |
S-Adenosyl-L-methionine
A
L-2-aminobutyric acid
B
5'-Deoxy-5'-methylthioadenosine
Conditions | Yield |
---|---|
With glycerol dehydratase activating enzyme aq. buffer; Enzymatic reaction; |
L-methionine
ATP
A
S-Adenosyl-L-methionine
B
5'-Deoxy-5'-methylthioadenosine
Conditions | Yield |
---|---|
With recombinant Methanocaldococcus jannaschii methionine adenosyltransferase; potassium chloride; magnesium chloride In aq. buffer at 65℃; for 4h; pH=8; Temperature; Reagent/catalyst; Enzymatic reaction; |
Conditions | Yield |
---|---|
With hydrogenchloride; GLUTATHIONE; human methionine adenosyltransferase plasmid MATI; potassium chloride; magnesium chloride In aq. buffer at 23℃; for 0.333333h; pH=8; Catalytic behavior; Kinetics; Enzymatic reaction; | |
With methionine adenosyltransferase from Methanocaldococcus jannaschii In aq. buffer at 65℃; for 1h; pH=8; Reagent/catalyst; Enzymatic reaction; |
5'-Deoxy-5'-methylthioadenosine
Conditions | Yield |
---|---|
With Pyrococcus horikoshii Dph2; dithionite(2-) In aq. acetate buffer at 20℃; for 0.333333h; pH=7.4; Inert atmosphere; Enzymatic reaction; |
Conditions | Yield |
---|---|
Stage #1: adenosine With thionyl chloride Stage #2: sodium thiomethoxide |
5'-Deoxy-5'-methylthioadenosine
2,2-dimethoxy-propane
9-((3aR,4R,6S,6aS)-2,2-dimethyl-6-((methylthio)methyl)tetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-9H-purin-6-amine
Conditions | Yield |
---|---|
With toluene-4-sulfonic acid In acetone at 20℃; for 2h; | 99% |
acetic anhydride
5'-Deoxy-5'-methylthioadenosine
2',3'-Di-O-acetyl-5'-deoxy-5'-(methylthio)adenosine
Conditions | Yield |
---|---|
With pyridine at 0℃; for 7h; | 98% |
With pyridine at 0 - 10℃; for 6h; | 87% |
With dmap; triethylamine In acetonitrile for 1h; Ambient temperature; | 78% |
With dmap; triethylamine In acetonitrile for 1h; | 75% |
5'-Deoxy-5'-methylthioadenosine
Conditions | Yield |
---|---|
With adenylate deaminase; dimethyl sulfoxide In phosphate buffer for 0.05h; pH=6.5; | 95% |
5'-Deoxy-5'-methylthioadenosine
5'-S-methyl-5'-thioinosine
Conditions | Yield |
---|---|
With phosphate buffer pH 6.8; ethanethiol In water α-amylase from Aspergillus oryzae; | 93% |
With acetic acid; sodium nitrite | |
With adenosine deaminase from Plasmodium falciparum In phosphate buffer at 30℃; pH=7.0; Enzyme kinetics; Enzymatic reaction; |
Conditions | Yield |
---|---|
With formic acid; silver perchlorate; acetic acid at 0 - 20℃; for 5.33333h; | 87% |
Conditions | Yield |
---|---|
With pyridine for 16h; Ambient temperature; | 85% |
Conditions | Yield |
---|---|
With formic acid for 72h; Ambient temperature; | 84.1% |
Conditions | Yield |
---|---|
With hydrogen; nickel In water at 90℃; under 3102.9 Torr; for 48h; | 83% |
methyl bromide
5'-Deoxy-5'-methylthioadenosine
5'-deoxy-5'-dimethylsulfunioadenosine bromide
Conditions | Yield |
---|---|
In formic acid; diethyl ether; acetic acid at 20℃; for 144h; Darkness; | 65% |
Conditions | Yield |
---|---|
Stage #1: 5'-Deoxy-5'-methylthioadenosine With 1-methyl-1H-imidazole In dichloromethane at 0℃; for 0.0833333h; Stage #2: carbonochloridic acid, butyl ester In dichloromethane at 0 - 20℃; for 72h; | 65% |
Conditions | Yield |
---|---|
Stage #1: 5'-Deoxy-5'-methylthioadenosine With 1-methyl-1H-imidazole In dichloromethane at 0℃; for 0.0833333h; Stage #2: n-hexyl chloroformate In dichloromethane at 0 - 20℃; for 72h; | 61% |
Conditions | Yield |
---|---|
Stage #1: 5'-Deoxy-5'-methylthioadenosine With 1-methyl-1H-imidazole In dichloromethane at 0℃; for 0.0833333h; Stage #2: chloroformic acid ethyl ester In dichloromethane at 0 - 20℃; for 72h; | 57% |
Conditions | Yield |
---|---|
Stage #1: 5'-Deoxy-5'-methylthioadenosine With 1-methyl-1H-imidazole In dichloromethane at 0℃; for 0.0833333h; Stage #2: 2-Methoxyethyl chloroformate In dichloromethane at 0 - 20℃; for 72h; | 56% |
Conditions | Yield |
---|---|
Stage #1: 5'-Deoxy-5'-methylthioadenosine With 1-methyl-1H-imidazole In dichloromethane at 0℃; for 0.0833333h; Stage #2: isopropyl chloroformate In dichloromethane at 0 - 20℃; for 72h; | 52% |
Conditions | Yield |
---|---|
Stage #1: 5'-Deoxy-5'-methylthioadenosine With 1-methyl-1H-imidazole In dichloromethane at 0℃; for 0.0833333h; Stage #2: propoxycarbonyl chloride In dichloromethane at 0 - 20℃; for 72h; | 46% |
5'-Deoxy-5'-methylthioadenosine
Conditions | Yield |
---|---|
With trifluoroacetic acid In methanol Heating; | A 15% B 40% |
5'-Deoxy-5'-methylthioadenosine
p-toluenesulfonyl chloride
S-methyl-N6,O2',O3'-tris-(toluene-4-sulfonyl)-5'-thio-adenosine
Conditions | Yield |
---|---|
With pyridine |
5'-Deoxy-5'-methylthioadenosine
methyl iodide
5'-(dimethylsulfonio)-5'-deoxyadenosine iodide
Conditions | Yield |
---|---|
With acetic acid | |
With formic acid | |
With formic acid at 40℃; |
5'-Deoxy-5'-methylthioadenosine
S-methyl-5-thio-D-ribose
Conditions | Yield |
---|---|
With sulfuric acid | |
With hydrogenchloride |
5'-Deoxy-5'-methylthioadenosine
9-((3aR,4R,6S,6aS)-2,2-dimethyl-6-((methylthio)methyl)tetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-9H-purin-6-amine
Conditions | Yield |
---|---|
With acetone; zinc(II) chloride |
acetic anhydride
5'-Deoxy-5'-methylthioadenosine
2',3'-Di-O-acetyl-5'-deoxy-5'-(methylthio)adenosine sulfoxide
Conditions | Yield |
---|---|
With pyridine; 3-chloro-benzenecarboperoxoic acid 2.) CH2Cl2, -40 deg C; Multistep reaction; |
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