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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

PHENYL(PIPERIDIN-4-YL)METHANONE HYDROCHLORIDE

Cas:25519-80-6

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1, High quality with competitive price: 1) Standard:BP/USP/EP/Enterprise standard 2) All Purity≥99% 3) We are manufacturer and can provide high quality products with factory price. 2, Fast and safe delivery 1) Parcel can be

4-BENZOYLPIPERIDINE HYDROCHLORIDE CAS:25519-80-6

Cas:25519-80-6

Min.Order:1 Kilogram

FOB Price: $30.0 / 40.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Methanone,phenyl-4-piperidinyl-, hydrochloride (1:1) 25519-80-6

Cas:25519-80-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

Phenyl(piperidin-4-yl)methanone hydrochloride

Cas:25519-80-6

Min.Order:1 Gram

FOB Price: $789.0

Type:Trading Company

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 4-Benzoylpiperidine hydrochloride

Cas:25519-80-6

Min.Order:0 Metric Ton

Negotiable

Type:Other

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Methanone,phenyl-4-piperidinyl-, hydrochloride (1:1)

Cas:25519-80-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

4-BENZOYLPIPERIDINE HYDROCHLORIDE

Cas:25519-80-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

4-BENZOYLPIPERIDINE HYDROCHLORIDE

Cas:25519-80-6

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, in

4-Benzoylpiperidine hydrochloride

Cas:25519-80-6

Min.Order:1 Kilogram

FOB Price: $300.0 / 400.0

Type:Lab/Research institutions

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

Phenyl(piperidin-4-yl)Methanone hydrochloride

Cas:25519-80-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

Methanone,phenyl-4-piperidinyl-, hydrochloride (1:1)

Cas:25519-80-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

4-Benzoylpiperidine Hydrochloride

Cas:25519-80-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Guangdong Juda Chemical Industrial Co.,Limited

Appearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China

4-BENZOYLPIPERIDINE HYDROCHLORIDE CAS No.25519-80-6

Cas:25519-80-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

4-BENZOYLPIPERIDINE HYDROCHLORIDE

Cas:25519-80-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

AstaTech ( Chengdu) BioPharmaceutical Corp.

Quality assurance, stable process and affordable priceAppearance:detailed see specifications Storage:enquiry Package:according to the clients requirement Application:Pharmaceutical intermediates Transportation:Normal Port:chengdu

4-BENZOYLPIPERIDINE HYDROCHLORIDE

Cas:25519-80-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

home-produced Application:medicine

4-BENZOYLPIPERIDINE HYDROCHLORIDE

Cas:25519-80-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Bide Pharmatech Ltd

Our mission is to provide high-quality and innovative products to our customers. By offering a broad range of products, custom synthesis and personalized services, Bide can help scientists speeding up their research in the chemical and pharmaceutical

Phenyl(piperidin-4-yl)methanone hydrochloride

Cas:25519-80-6

Min.Order:0

Negotiable

Type:Other

inquiry

Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

phenyl(4-piperidin-1-iumyl)methanone

Cas:25519-80-6

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

Jilin haofei import and export trade Co.,Ltd

Price, service, company and transport advantage: 1. Best service, place of origin China, high quality, and reasonable price. 2. It's customers' right to choose the package (EMS, DHL, FEDEX, UPS). 3. It's customers' right

PHENYL(PIPERIDIN-4-YL)METHANONE HYDROCHLORIDE CAS NO.25519-80-6

Cas:25519-80-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Watson International Ltd

Watson International Ltd' has a very strong R&D and technical capacity supported by FCAD's platform. The subsidiaries under FCAD Group have accumulated much know-how of different fine chemical branches. For example, Apnoke Scientific L

4-Benzoylpiperidine hydrochloride

Cas:25519-80-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

ENAO Chemical Co, Limited

For quick quotation, please send us the inquiry include CAS#, Structure, Chemical Name, quantity, purity, as well as any additional specifications you require, we will try to get back to you within 24 hours. Our Services Besides manufacturing,

Phenyl(piperidin-4-yl)methanone hydrochloride

Cas:25519-80-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Share Chemical Co., Ltd

At Share Chemical Company, we scrupulously abide by our policy of “Excellent Quality at a Reasonable Price”. We strive to satisfy all of our customers by providing the finest quality products supported by the finest in customer servi

4-Benzoylpiperidine hydrochloride

Cas:25519-80-6

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Capot Chemical Co., Ltd.

At Capot,We can synthesize and purify your complex molecules from 100 gram to 10 tons.Appearance:Clear colorless to light yellow liquid Storage:Dry,Seal and Cool place Package:1G,5G,10G,25G,100G,250G,500G,1KG,5KG,10KG,25KG,50KG,100KG,150KG,200KG. App

phenyl(4-piperidyl)methanone hydrochloride

Cas:25519-80-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Finetech Industry Limited

FINETECH INDUSTRY LIMITED is a LONDON based CRO company providing drug discovery & development services to worldwide clients. FINETECH INDUSTRY LIMITED supplies the 4-Benzoylpiperidine Hydrochloride, CAS:25519-80-6 with the most competitive price and

4-BENZOYLPIPERIDINE HYDROCHLORIDE

Cas:25519-80-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

GZ HONESTCHEM CO., LTD

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

Phenyl(piperidin-4-yl)Methanone hydrochloride

Cas:25519-80-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Tianjin SPHINX SCIENTIFIC LAB.

Package:1g,5g,10g

4-Benzoylpiperidine hydrochloride

Cas:25519-80-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Debye Scientific

Debyesci is here who supplied several kinds of chemical products to global pharmaceutical, drug discovery, agrochemical and biotechnology industries for four yearsOur key scientific leadership team has gained experience in top research and developmen

4-benzoylpiperidine hydrochloride

Cas:25519-80-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai chamflyer chemicals Co., Ltd

High quality Application:Pharmaceutial

Phenyl(piperidin-4-yl)Methanone hydrochloride

Cas:25519-80-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

NovaChemistry

high purity Application:Drug intermediates Materials intermediates and active molecules

Phenyl(4-piperidinyl)methanone HCl

Cas:25519-80-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Dr.Prem's Molecules

4-Benzoylpiperidine hydrochloride

Cas:25519-80-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

1-(t-butoxycarbonyl)-4-(benzoyl)piperidine
193217-39-9

1-(t-butoxycarbonyl)-4-(benzoyl)piperidine

4-(benzoyl)piperidine hydrochloride
25519-80-6

4-(benzoyl)piperidine hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In 1,4-dioxane at 18 - 25℃; for 0.5h;98%
With hydrogenchloride In 1,4-dioxane
1-(4-benzoylpiperidin-1-yl)ethanone
25519-79-3

1-(4-benzoylpiperidin-1-yl)ethanone

4-(benzoyl)piperidine hydrochloride
25519-80-6

4-(benzoyl)piperidine hydrochloride

Conditions
ConditionsYield
With hydrogenchloride; water In tetrahydrofuran for 10h; Reflux;
1-acetyl-piperidine-4-carboxylic acid
25503-90-6

1-acetyl-piperidine-4-carboxylic acid

4-(benzoyl)piperidine hydrochloride
25519-80-6

4-(benzoyl)piperidine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: thionyl chloride; N,N-dimethyl-formamide / 1,2-dichloro-ethane / 4 h / 0 - 60 °C
2: aluminum (III) chloride / 1,2-dichloro-ethane / 16 h / 0 - 65 °C
3: hydrogenchloride; water / tetrahydrofuran / 10 h / Reflux
View Scheme
isonipecotic acid
498-94-2

isonipecotic acid

4-(benzoyl)piperidine hydrochloride
25519-80-6

4-(benzoyl)piperidine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: pyridine / 2 h / 140 °C
2: thionyl chloride; N,N-dimethyl-formamide / 1,2-dichloro-ethane / 4 h / 0 - 60 °C
3: aluminum (III) chloride / 1,2-dichloro-ethane / 16 h / 0 - 65 °C
4: hydrogenchloride; water / tetrahydrofuran / 10 h / Reflux
View Scheme
1-acetylpiperidine-4-carbonyl chloride
59084-16-1

1-acetylpiperidine-4-carbonyl chloride

4-(benzoyl)piperidine hydrochloride
25519-80-6

4-(benzoyl)piperidine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: aluminum (III) chloride / 1,2-dichloro-ethane / 16 h / 0 - 65 °C
2: hydrogenchloride; water / tetrahydrofuran / 10 h / Reflux
View Scheme
benzyl chloroformate
501-53-1

benzyl chloroformate

4-(benzoyl)piperidine hydrochloride
25519-80-6

4-(benzoyl)piperidine hydrochloride

4-benzoylpiperidine-1-carboxylic acid benzyl ester
922504-27-6

4-benzoylpiperidine-1-carboxylic acid benzyl ester

Conditions
ConditionsYield
With potassium carbonate In tetrahydrofuran at 0 - 20℃; for 2h;100%
With potassium carbonate In tetrahydrofuran at 0 - 25℃; for 15h; Inert atmosphere;97.76%
With potassium carbonate In tetrahydrofuran at 0 - 20℃; for 2h;90%
With potassium carbonate In 1,4-dioxane; water Cooling with ice;1.43 g
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

4-(benzoyl)piperidine hydrochloride
25519-80-6

4-(benzoyl)piperidine hydrochloride

1-(t-butoxycarbonyl)-4-(benzoyl)piperidine
193217-39-9

1-(t-butoxycarbonyl)-4-(benzoyl)piperidine

Conditions
ConditionsYield
With potassium hydrogencarbonate In tetrahydrofuran; water for 1h; Condensation; Heating;98%
With sodium carbonate In tetrahydrofuran; water for 1h; Heating;98%
With potassium hydrogencarbonate In H2 O-TBF98%
4-(benzoyl)piperidine hydrochloride
25519-80-6

4-(benzoyl)piperidine hydrochloride

1-methyl-1H-imidazole-4-sulfonyl chloride
137049-00-4

1-methyl-1H-imidazole-4-sulfonyl chloride

(1-(1-Methyl-1H-Imidazol-4-ylsulfonyl)Piperidin-4-yl)(Phenyl)Methanone
1246526-78-2

(1-(1-Methyl-1H-Imidazol-4-ylsulfonyl)Piperidin-4-yl)(Phenyl)Methanone

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dichloromethane for 18h;93%
2-(benzylthio)-4-(4-methoxyphenyl)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile
138608-95-4

2-(benzylthio)-4-(4-methoxyphenyl)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile

4-(benzoyl)piperidine hydrochloride
25519-80-6

4-(benzoyl)piperidine hydrochloride

C31H28N4O2S
1425974-12-4

C31H28N4O2S

Conditions
ConditionsYield
With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; 1,8-diazabicyclo[5.4.0]undec-7-ene In acetonitrile at 20℃; for 12h;70%
4-(benzoyl)piperidine hydrochloride
25519-80-6

4-(benzoyl)piperidine hydrochloride

2-Benzylsulfanyl-4-(4-chloro-phenyl)-6-oxo-1,6-dihydro-pyrimidine-5-carbonitrile

2-Benzylsulfanyl-4-(4-chloro-phenyl)-6-oxo-1,6-dihydro-pyrimidine-5-carbonitrile

C30H25ClN4OS
1425974-03-3

C30H25ClN4OS

Conditions
ConditionsYield
With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; 1,8-diazabicyclo[5.4.0]undec-7-ene In acetonitrile at 20℃; for 12h;64%
4-(benzoyl)piperidine hydrochloride
25519-80-6

4-(benzoyl)piperidine hydrochloride

1-(4-Chlorobutyl)-7-methyl-6,7-dihydropyrrolo[2,3-c]azepine-4,8(1H,5H)-dione
136975-57-0

1-(4-Chlorobutyl)-7-methyl-6,7-dihydropyrrolo[2,3-c]azepine-4,8(1H,5H)-dione

1-[4-(4-benzoyl-piperidin-1-yl)-butyl]-7-methyl-6,7-dihydro-1H,5H-pyrrolo[2,3-c]azepine-4,8-dione

1-[4-(4-benzoyl-piperidin-1-yl)-butyl]-7-methyl-6,7-dihydro-1H,5H-pyrrolo[2,3-c]azepine-4,8-dione

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 80℃; for 16h;61%
1,1-dimethylethyl[trans-4-(2-oxoethyl)cyclohexyl]carbamate
215790-29-7

1,1-dimethylethyl[trans-4-(2-oxoethyl)cyclohexyl]carbamate

4-(benzoyl)piperidine hydrochloride
25519-80-6

4-(benzoyl)piperidine hydrochloride

{trans-4-[2-(4-benzoyl-piperidin-1-yl)-ethyl]-cyclohexyl}-carbamic acid tert-butyl ester

{trans-4-[2-(4-benzoyl-piperidin-1-yl)-ethyl]-cyclohexyl}-carbamic acid tert-butyl ester

Conditions
ConditionsYield
Stage #1: 1,1-dimethylethyl[trans-4-(2-oxoethyl)cyclohexyl]carbamate; 4-(benzoyl)piperidine hydrochloride With acetic acid In 1,2-dichloro-ethane at 20℃;
Stage #2: With sodium tris(acetoxy)borohydride In 1,2-dichloro-ethane
Stage #3: With water; sodium hydrogencarbonate In 1,2-dichloro-ethane
49%
3-(benzyloxy)-6-bromo-2,4,5-trimethylpyridine
1444336-77-9

3-(benzyloxy)-6-bromo-2,4,5-trimethylpyridine

4-(benzoyl)piperidine hydrochloride
25519-80-6

4-(benzoyl)piperidine hydrochloride

(1-(5-(benzyloxy)-3,4,6-trimethylpyridin-2-yl)piperidin-4-yl)(phenyl)methanone

(1-(5-(benzyloxy)-3,4,6-trimethylpyridin-2-yl)piperidin-4-yl)(phenyl)methanone

Conditions
ConditionsYield
With tris-(dibenzylideneacetone)dipalladium(0); 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate In toluene at 130℃; for 24h;27%
4-(benzoyl)piperidine hydrochloride
25519-80-6

4-(benzoyl)piperidine hydrochloride

benzenesulfenyl chloride
931-59-9

benzenesulfenyl chloride

4-benzoylpiperidine-1-benzenesulfenamide
74129-96-7

4-benzoylpiperidine-1-benzenesulfenamide

Conditions
ConditionsYield
With triethylamine In dichloromethane for 2.5h; Ambient temperature;13.2%
4-(benzoyl)piperidine hydrochloride
25519-80-6

4-(benzoyl)piperidine hydrochloride

1-(4-tert-Butyl-phenyl)-4-iodo-butan-1-one

1-(4-tert-Butyl-phenyl)-4-iodo-butan-1-one

4-(4-benzoylpiperidin-1-yl)-1-<4-(1,1-dimethylethyl)phenyl>-1-butanone
151091-52-0

4-(4-benzoylpiperidin-1-yl)-1-<4-(1,1-dimethylethyl)phenyl>-1-butanone

Conditions
ConditionsYield
With potassium carbonate In acetone Heating; Yield given;
4-(benzoyl)piperidine hydrochloride
25519-80-6

4-(benzoyl)piperidine hydrochloride

tert-butyl (S)-4-(hydroxy(phenyl)methyl)piperidine-1-carboxylate

tert-butyl (S)-4-(hydroxy(phenyl)methyl)piperidine-1-carboxylate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 89 percent / sodium carbonate / H2O; tetrahydrofuran / 1 h / 80 °C
2: formic acid; triethylamine / [((S,S)-N-(1,2,6-triphenyl-3-azahexyl)tosylamido)RuCl] / 16 h / 40 °C
View Scheme
4-(benzoyl)piperidine hydrochloride
25519-80-6

4-(benzoyl)piperidine hydrochloride

tert-butyl (R)-4-(hydroxy(phenyl)methyl)piperidine-1-carboxylate

tert-butyl (R)-4-(hydroxy(phenyl)methyl)piperidine-1-carboxylate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 89 percent / sodium carbonate / H2O; tetrahydrofuran / 1 h / 80 °C
2: formic acid; triethylamine / [((S,S)-N-(1,2,6-triphenyl-3-azahexyl)tosylamido)RuCl] / 16 h / 40 °C
View Scheme
4-(benzoyl)piperidine hydrochloride
25519-80-6

4-(benzoyl)piperidine hydrochloride

4-(hydroxyphenylmethyl)piperidine-1-carboxylic acid tert-butyl ester
269740-46-7, 269741-35-7

4-(hydroxyphenylmethyl)piperidine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 89 percent / sodium carbonate / H2O; tetrahydrofuran / 1 h / 80 °C
2: sodium borohydride
View Scheme
4-(benzoyl)piperidine hydrochloride
25519-80-6

4-(benzoyl)piperidine hydrochloride

N,N-diethyl-4-(phenyl-piperidin-4-yl-methyl)-benzamide

N,N-diethyl-4-(phenyl-piperidin-4-yl-methyl)-benzamide

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: 98 percent / KHCO3 / tetrahydrofuran; H2O / 1 h / Heating
2.1: t-BuLi / tetrahydrofuran; hexane / -78 °C
2.2: 94 percent / tetrahydrofuran; hexane / -78 - 20 °C
3.1: 82 percent / Et3SiH; TFA / CH2Cl2 / 72 h / 25 °C
View Scheme
4-(benzoyl)piperidine hydrochloride
25519-80-6

4-(benzoyl)piperidine hydrochloride

AR-M390
209808-01-5

AR-M390

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: 98 percent / Na2CO3 / tetrahydrofuran; H2O / 1 h / Heating
2.1: t-BuLi / tetrahydrofuran / 0.17 h / -78 °C
2.2: 94 percent / tetrahydrofuran / -78 - 20 °C
3.1: 91 percent / TFA / CH2Cl2 / 20 °C
View Scheme
4-(benzoyl)piperidine hydrochloride
25519-80-6

4-(benzoyl)piperidine hydrochloride

N,N-Diethyl-4-[(1-methyl-piperidin-4-ylidene)-phenyl-methyl]-benzamide

N,N-Diethyl-4-[(1-methyl-piperidin-4-ylidene)-phenyl-methyl]-benzamide

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: 98 percent / Na2CO3 / tetrahydrofuran; H2O / 1 h / Heating
2.1: t-BuLi / tetrahydrofuran / 0.17 h / -78 °C
2.2: 94 percent / tetrahydrofuran / -78 - 20 °C
3.1: 91 percent / TFA / CH2Cl2 / 20 °C
4.1: 48 mg / K2CO3 / acetonitrile / 0.5 h / 25 °C
View Scheme
4-(benzoyl)piperidine hydrochloride
25519-80-6

4-(benzoyl)piperidine hydrochloride

N,N-Diethyl-4-(phenyl-N-allyl-piperidin-4-ylidene-methyl)-benzamide

N,N-Diethyl-4-(phenyl-N-allyl-piperidin-4-ylidene-methyl)-benzamide

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: 98 percent / Na2CO3 / tetrahydrofuran; H2O / 1 h / Heating
2.1: t-BuLi / tetrahydrofuran / 0.17 h / -78 °C
2.2: 94 percent / tetrahydrofuran / -78 - 20 °C
3.1: 91 percent / TFA / CH2Cl2 / 20 °C
4.1: 86 percent / K2CO3 / acetonitrile / 0.5 h / 25 °C
View Scheme
4-(benzoyl)piperidine hydrochloride
25519-80-6

4-(benzoyl)piperidine hydrochloride

N,N-diethyl-4-[phenyl-(1-phenyl-piperidin-4-ylidene)-methyl]-benzamide

N,N-diethyl-4-[phenyl-(1-phenyl-piperidin-4-ylidene)-methyl]-benzamide

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: 98 percent / Na2CO3 / tetrahydrofuran; H2O / 1 h / Heating
2.1: t-BuLi / tetrahydrofuran / 0.17 h / -78 °C
2.2: 94 percent / tetrahydrofuran / -78 - 20 °C
3.1: 91 percent / TFA / CH2Cl2 / 20 °C
4.1: 56 percent / Pd(dba)2; BINAP; sodium tert-butoxide / toluene / 12 h / 80 - 90 °C
View Scheme
4-(benzoyl)piperidine hydrochloride
25519-80-6

4-(benzoyl)piperidine hydrochloride

4-[(1-cyclopropylmethyl-piperidin-4-ylidene)-phenyl-methyl]-N,N-diethyl-benzamide

4-[(1-cyclopropylmethyl-piperidin-4-ylidene)-phenyl-methyl]-N,N-diethyl-benzamide

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: 98 percent / Na2CO3 / tetrahydrofuran; H2O / 1 h / Heating
2.1: t-BuLi / tetrahydrofuran / 0.17 h / -78 °C
2.2: 94 percent / tetrahydrofuran / -78 - 20 °C
3.1: 91 percent / TFA / CH2Cl2 / 20 °C
4.1: 86 percent / K2CO3 / acetonitrile / 0.5 h / 25 °C
View Scheme
4-(benzoyl)piperidine hydrochloride
25519-80-6

4-(benzoyl)piperidine hydrochloride

4-[(1-butyl-piperidin-4-ylidene)-phenyl-methyl]-N,N-diethyl-benzamide

4-[(1-butyl-piperidin-4-ylidene)-phenyl-methyl]-N,N-diethyl-benzamide

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: 98 percent / Na2CO3 / tetrahydrofuran; H2O / 1 h / Heating
2.1: t-BuLi / tetrahydrofuran / 0.17 h / -78 °C
2.2: 94 percent / tetrahydrofuran / -78 - 20 °C
3.1: 91 percent / TFA / CH2Cl2 / 20 °C
4.1: 85 percent / K2CO3 / acetonitrile / 0.5 h / 25 °C
View Scheme
4-(benzoyl)piperidine hydrochloride
25519-80-6

4-(benzoyl)piperidine hydrochloride

N,N-Diethyl-4-[(N-3-methyl-2-butenyl)-phenyl-piperidin-4-ylidene-methyl]-benzamide

N,N-Diethyl-4-[(N-3-methyl-2-butenyl)-phenyl-piperidin-4-ylidene-methyl]-benzamide

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: 98 percent / Na2CO3 / tetrahydrofuran; H2O / 1 h / Heating
2.1: t-BuLi / tetrahydrofuran / 0.17 h / -78 °C
2.2: 94 percent / tetrahydrofuran / -78 - 20 °C
3.1: 91 percent / TFA / CH2Cl2 / 20 °C
4.1: 71 percent / K2CO3 / acetonitrile / 0.5 h / 25 °C
View Scheme
4-(benzoyl)piperidine hydrochloride
25519-80-6

4-(benzoyl)piperidine hydrochloride

4-(α-hydroxy-α-(4-N-tert-butoxycarbonylpiperidinyl)benzyl)-N,N-diethylbenzamide
193217-40-2

4-(α-hydroxy-α-(4-N-tert-butoxycarbonylpiperidinyl)benzyl)-N,N-diethylbenzamide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: 98 percent / KHCO3 / tetrahydrofuran; H2O / 1 h / Heating
2.1: t-BuLi / tetrahydrofuran; hexane / -78 °C
2.2: 94 percent / tetrahydrofuran; hexane / -78 - 20 °C
View Scheme
Multi-step reaction with 2 steps
1.1: 98 percent / Na2CO3 / tetrahydrofuran; H2O / 1 h / Heating
2.1: t-BuLi / tetrahydrofuran / 0.17 h / -78 °C
2.2: 94 percent / tetrahydrofuran / -78 - 20 °C
View Scheme
4-(benzoyl)piperidine hydrochloride
25519-80-6

4-(benzoyl)piperidine hydrochloride

4-[(1-cyclohexyl-piperidin-4-ylidene)-phenyl-methyl]-N,N-diethyl-benzamide

4-[(1-cyclohexyl-piperidin-4-ylidene)-phenyl-methyl]-N,N-diethyl-benzamide

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: 98 percent / Na2CO3 / tetrahydrofuran; H2O / 1 h / Heating
2.1: t-BuLi / tetrahydrofuran / 0.17 h / -78 °C
2.2: 94 percent / tetrahydrofuran / -78 - 20 °C
3.1: 91 percent / TFA / CH2Cl2 / 20 °C
4.1: Ti(OPr-i)4 / 20 °C / microwave irradiation
4.2: 20 percent / NaBH4 / ethanol / 12 h / 20 °C
View Scheme
4-(benzoyl)piperidine hydrochloride
25519-80-6

4-(benzoyl)piperidine hydrochloride

1-<4-<4-(1,1-dimethylethyl)phenyl>-4-hydroxybutyl>-α-phenyl-4-piperidinomethanol

1-<4-<4-(1,1-dimethylethyl)phenyl>-4-hydroxybutyl>-α-phenyl-4-piperidinomethanol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: K2CO3 / acetone / Heating
2: 98 percent / NaBH4 / methanol / 2 h / Ambient temperature
View Scheme
methanesulfonyl chloride
124-63-0

methanesulfonyl chloride

4-(benzoyl)piperidine hydrochloride
25519-80-6

4-(benzoyl)piperidine hydrochloride

4-benzoyl-1-methanesulphonylpiperidine
515154-31-1

4-benzoyl-1-methanesulphonylpiperidine

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 25℃; for 16h;
With triethylamine In dichloromethane at 0 - 20℃; for 16h;
With triethylamine In dichloromethane at 0 - 20℃; for 16h;
With triethylamine In dichloromethane at 0 - 20℃; for 16h;
With triethylamine In dichloromethane at 0 - 20℃; for 16h;
4-(benzoyl)piperidine hydrochloride
25519-80-6

4-(benzoyl)piperidine hydrochloride

trifluoroacetic anhydride
407-25-0

trifluoroacetic anhydride

A

4-(2-nitrobenzoyl)-1-trifluoromethylcarbonylpiperidine

4-(2-nitrobenzoyl)-1-trifluoromethylcarbonylpiperidine

B

N-trifluoroacetyl-4-(m-nitrobenzoyl)piperidine

N-trifluoroacetyl-4-(m-nitrobenzoyl)piperidine

C

N-trifluoroacetyl-4-(p-nitrobenzoyl)piperidine

N-trifluoroacetyl-4-(p-nitrobenzoyl)piperidine

Conditions
ConditionsYield
Stage #1: 4-(benzoyl)piperidine hydrochloride; trifluoroacetic anhydride at 20℃; for 21h; Heating / reflux;
Stage #2: With ammonium nitrate In trifluoroacetic anhydride at 5 - 10℃; for 1.75h;
Stage #1: 4-(benzoyl)piperidine hydrochloride; trifluoroacetic anhydride at 20℃; for 27h; Heating / reflux;
Stage #2: With nitric acid In trifluoroacetic anhydride at 5 - 10℃; for 1.33333h;
4-(benzoyl)piperidine hydrochloride
25519-80-6

4-(benzoyl)piperidine hydrochloride

phenylmagnesium bromide
100-58-3

phenylmagnesium bromide

4-(diphenylmethylene)piperidine
50706-57-5

4-(diphenylmethylene)piperidine

Conditions
ConditionsYield
Stage #1: 4-(benzoyl)piperidine hydrochloride; phenylmagnesium bromide In tetrahydrofuran at 20℃; for 12h;
Stage #2: With trifluoroacetic acid for 12h;
Stage #3: With sodium hydrogencarbonate In water; ethyl acetate
intermediate 4
625099-22-1

intermediate 4

4-(benzoyl)piperidine hydrochloride
25519-80-6

4-(benzoyl)piperidine hydrochloride

A

C30H36F3N3O2

C30H36F3N3O2

B

C30H36F3N3O2

C30H36F3N3O2

C

C30H36F3N3O2

C30H36F3N3O2

D

C30H36F3N3O2

C30H36F3N3O2

Conditions
ConditionsYield
Stage #1: intermediate 4; 4-(benzoyl)piperidine hydrochloride With sodium tris(acetoxy)borohydride; N-ethyl-N,N-diisopropylamine In dichloromethane Molecular sieve;
Stage #2: With water; sodium hydrogencarbonate In dichloromethane
Stage #1: intermediate 4; 4-(benzoyl)piperidine hydrochloride With N-ethyl-N,N-diisopropylamine In dichloromethane
Stage #2: With sodium tris(acetoxy)borohydride In dichloromethane for 16h;
4-(benzoyl)piperidine hydrochloride
25519-80-6

4-(benzoyl)piperidine hydrochloride

1,3-chlorobromopropane
109-70-6

1,3-chlorobromopropane

(1-(3-chloropropyl)piperidin-4-yl)(phenyl)methanone
106134-85-4

(1-(3-chloropropyl)piperidin-4-yl)(phenyl)methanone

Conditions
ConditionsYield
With sodium hydroxide; tetra(n-butyl)ammonium hydrogen sulfate In water; toluene

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