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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

Methyl 3-oxo-4-androstene-17beta-carboxylate Manufacturer/High quality/Best price/In stock

Cas:2681-55-2

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Methyl 3-Oxo-4-Androstene-17Β-Carboxylate supplier in China

Cas:2681-55-2

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm

Methyl 3-oxo-4-androstene-17beta-carboxylate Manufacturer

Cas:2681-55-2

Min.Order:1 Metric Ton

FOB Price: $1.0 / 3.0

Type:Manufacturers

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Hangzhou Think Chemical Co. Ltd

Methyl-3-Oxo-4-androstene-17β-carboxylate (F4) CAS:2681-55-2 Finasteride intermediate Related: 3-Oxo-4-androstene-17β-carboxylic acid Finasteride Name Methyl 3-oxo-4-androstene-17beta-carboxylate

Methyl 3-oxo-4-androstene-17beta-carboxylate for Finasteride

Cas:2681-55-2

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Methyl (17β)-3-oxo-androst-4-ene-17-carboxylate

Cas:2681-55-2

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

top Methyl 3-oxo-4-androstene-17beta-carboxylate

Cas:2681-55-2

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

Methyl 3-oxo-4-androstene-17beta-carboxylate

Cas:2681-55-2

Min.Order:1 Kilogram

FOB Price: $100.0 / 150.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 2681-55-2 with best quality

Cas:2681-55-2

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

METHYL 4-ANDROSTEN-3-ONE-17 BETA-CARBOXYLINATE(F4)

Cas:2681-55-2

Min.Order:10 Gram

FOB Price: $0.5 / 1.0

Type:Trading Company

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Methyl 3-oxo-4-androstene-17beta-carboxylate/ LIDE PHARMA- Factory supply / Best price

Cas:2681-55-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:White Crystalline Powder Storage:Store in sealed conta

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Androst-4-ene-17-carboxylicacid, 3-oxo-, methyl ester, (17b)- 2681-55-2

Cas:2681-55-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

METHYL 4-ANDROSTEN-3-ONE-17 BETA-CARBOXYLINATE(F4)

Cas:2681-55-2

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

METHYL 3-OXO-4-ANDROSTENE-17BETA-CARBOXYLATE

Cas:2681-55-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Androst-4-ene-17-carboxylicacid, 3-oxo-, methyl ester, (17b)-

Cas:2681-55-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shaanxi Cuicheng Biomedical Technology Co., Ltd.

Why Choose Us: 1. Factory direct sales, so we can provide the competitive price and high quality product base on 8 years of production and R&D experience. 2. It is available in stock for quick shipment.Products could be packaged according to cu

Methyl 3-oxo-4-androstene-17beta-carboxylate

Cas:2681-55-2

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

METHYL 4-ANDROSTEN-3-ONE-17 BETA-CARBOXYLINATE(F4)

Cas:2681-55-2

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: Methyl 3-Oxo-4-Androstene-17beta-Carboxylate CAS No.: 2681-55-2 Molecule Formula:C21H30O3 Molecule Weight:330.46 Purity: 99.0% Package: 25kg/drum Description:White powder Manufacture Standards:Enterprise Standard TE

Lower Price Methyl 3-Oxo-4-Androstene-17beta-Carboxylate on stock

Cas:2681-55-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

Methyl 3-oxo-4-androstene-17beta-carboxylate

Cas:2681-55-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

METHYL 4-ANDROSTEN-3-ONE-17 BETA-CARBOXYLINATE(F4)

Cas:2681-55-2

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

METHYL 4-ANDROSTEN-3-ONE-17 BETA-CARBOXYLINATE(F4)

Cas:2681-55-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

METHYL 4-ANDROSTEN-3-ONE-17 BETA-CARBOXYLINATE(F4)

Cas:2681-55-2

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

Methyl-3-oxo-4-androstene-17β-carboxylate

Cas:2681-55-2

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

Methyl-4-androsten-3-one- 17beta-carboxylinate(F4)

Cas:2681-55-2

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white powder Storage:Sealed and stored in a cool,dark place Package:25kg/drum, or as per your request. Application:For medicine , pesticide intermediates Transportation:as per yo

Methyl 3-oxo-4-androstene-17beta-carboxylate

Cas:2681-55-2

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

METHYL 4-ANDROSTEN-3-ONE-17 BETA-CARBOXYLINATE(F4)

Cas:2681-55-2

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Hunan kingson pharmaceutical technology co.ltd

Product Name: Methyl 3-oxo-4-androstene-17beta-carboxylate Synonyms: METHYL 4-ANDROSTEN-3-ONE-17BETA-CARBOXYLINATE;Methyl-3-oxo-4-androstene-17beta-… Package:25kg/drum or as your demand Transportation:FOB Guangzhou or as your demand

Methyl 3-oxo-4-androstene-17beta-carboxylate

Cas:2681-55-2

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Lonwin Chemical Group Limited

Shanghai Lonwin Chemical company is a subsidiary of Lonwin Industry Group Limited, was established in 2011 and is headquartered in Shanghai, adjacent to China National Convention and Exhibition Center and Hongqiao transportation hub.Lonwinchem is

High Purity Methyl 3-Oxo-4-Androstene-17Β-Carboxylate 2681-55-2

Cas:2681-55-2

Min.Order:100 Kilogram

FOB Price: $100.0 / 150.0

Type:Other

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,or Intermediates,fine chemicals Transportation:air,sea,courier

Methyl-3-oxo-4-androstene-17beta-carboxylate

Cas:2681-55-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

JINHUA HUAYI CHEMICAL CO., LTD.

Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

Methyl-3-Oxo-4-Androstene-17β-Carboxylate

Cas:2681-55-2

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

17β-androstane-4-ene-3-keto-17-formaldehyde
6247-91-2

17β-androstane-4-ene-3-keto-17-formaldehyde

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

Conditions
ConditionsYield
With tert.-butylhydroperoxide; potassium iodide In methanol at 20℃; for 6.5h; Reagent/catalyst; Reflux;93%
androst-4-en-3-one-17β-carboxylic acid
302-97-6

androst-4-en-3-one-17β-carboxylic acid

temozolomide
85622-93-1

temozolomide

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

Conditions
ConditionsYield
With sodium carbonate In 1,4-dioxane; water at 60℃; for 4h; Sealed tube;89%
methyl 5-androsten-3β-ol-17β-carboxylate
85541-82-8, 95119-09-8, 7254-03-7

methyl 5-androsten-3β-ol-17β-carboxylate

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

Conditions
ConditionsYield
With cyclohexanone; aluminum isopropoxide In toluene87%
With aluminum isopropoxide In cyclohexanone; toluene at 110℃; for 3h; Oppenauer Oxidation; Inert atmosphere;82%
With aluminum isopropoxide In cyclohexanone; toluene for 4h; Oxidation; Oppennauer oxidation; Heating;70.62%
tert-butyl methyl ether
1634-04-4

tert-butyl methyl ether

androst-4-en-3-one-17β-carboxylic acid
302-97-6

androst-4-en-3-one-17β-carboxylic acid

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

Conditions
ConditionsYield
With iron(III) trifluoromethanesulfonate at 90℃; Schlenk technique;79%
methanol
67-56-1

methanol

C24H31NO2

C24H31NO2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

Conditions
ConditionsYield
With [2,2]bipyridinyl; bis(1,5-cyclooctadiene)nickel (0) In toluene at 20℃; for 18h; Sealed tube; chemoselective reaction;64%
methanol
67-56-1

methanol

17-Acetoxy-21-(acetylthio)-4-pregnen-3,20-dion
121329-22-4

17-Acetoxy-21-(acetylthio)-4-pregnen-3,20-dion

A

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

B

(17R)-4-Androsten-17-spiro-3'-(1',2'-dithiolan)-3,4'-dion
121329-29-1

(17R)-4-Androsten-17-spiro-3'-(1',2'-dithiolan)-3,4'-dion

Conditions
ConditionsYield
With sodium azide for 22h; Ambient temperature;A 48%
B 10%
17-Acetoxy-21-(acetylthio)-4-pregnen-3,20-dion
121329-22-4

17-Acetoxy-21-(acetylthio)-4-pregnen-3,20-dion

A

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

B

(17R)-4-Androsten-17-spiro-3'-(1',2'-dithiolan)-3,4'-dion
121329-29-1

(17R)-4-Androsten-17-spiro-3'-(1',2'-dithiolan)-3,4'-dion

Conditions
ConditionsYield
With sodium azide In methanol at 50℃; for 1.5h;A 8%
B 39%
androst-4-en-3-one-17β-carboxylic acid
302-97-6

androst-4-en-3-one-17β-carboxylic acid

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

Conditions
ConditionsYield
With diethyl ether
methyl 3-oxo-androst-1,4-diene-17β-carboxylate
111497-46-2

methyl 3-oxo-androst-1,4-diene-17β-carboxylate

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

Conditions
ConditionsYield
Hydrogenation;
2β,4β-dibromo-3-oxo-5β-androstane-17β-carboxylic acid methyl ester
114127-58-1

2β,4β-dibromo-3-oxo-5β-androstane-17β-carboxylic acid methyl ester

A

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

B

3-oxo-5β-androst-1-ene-17β-carboxylic acid methyl ester
111407-58-0

3-oxo-5β-androst-1-ene-17β-carboxylic acid methyl ester

Conditions
ConditionsYield
With acetone; sodium iodide Erwaermen des Reaktionsprodukts mit Zink-Pulver und Aethanol;
methyl 5-androsten-3β-ol-17β-carboxylate
85541-82-8, 95119-09-8, 7254-03-7

methyl 5-androsten-3β-ol-17β-carboxylate

cyclohexanone
108-94-1

cyclohexanone

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

Conditions
ConditionsYield
With aluminum isopropoxide; toluene
methyl 5-androsten-3β-ol-17β-carboxylate
85541-82-8, 95119-09-8, 7254-03-7

methyl 5-androsten-3β-ol-17β-carboxylate

cyclohexanone
108-94-1

cyclohexanone

aluminum isopropoxide
555-31-7

aluminum isopropoxide

toluene
108-88-3

toluene

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

2β,4β-dibromo-3-oxo-5β-androstane-17β-carboxylic acid methyl ester
114127-58-1

2β,4β-dibromo-3-oxo-5β-androstane-17β-carboxylic acid methyl ester

A

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

B

3-oxo-androst-1-ene-17β-carboxylic acid methyl ester

3-oxo-androst-1-ene-17β-carboxylic acid methyl ester

Conditions
ConditionsYield
With acetone; sodium iodide Erwaermen des Reaktionsprodukts mit Zink-Pulver und Aethanol;
3β,5-dihydroxy-21-nor-5β-pregnanoic acid-(20)-methyl ester
55955-57-2

3β,5-dihydroxy-21-nor-5β-pregnanoic acid-(20)-methyl ester

acetic acid
64-19-7

acetic acid

chromium (VI)-oxide

chromium (VI)-oxide

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

Conditions
ConditionsYield
Erhitzen des Reaktionsprodukts mit Essigsaeure;
17β-acetoxy-3β-hydroxy-3α-methylandrost-4-ene

17β-acetoxy-3β-hydroxy-3α-methylandrost-4-ene

A

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

B

17β-acetoxy-3β,4β-epoxy-5β-hydroxy-3α-methylandrostane

17β-acetoxy-3β,4β-epoxy-5β-hydroxy-3α-methylandrostane

Conditions
ConditionsYield
With chromium(VI) oxide In acetone at 20℃;A 50 mg
B 290 mg
3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: cesium fluoride / dimethylformamide / 24 h / 20 °C
2: 3.1 g / cyclohexanone; aluminium isopropoxide / toluene / Heating
View Scheme
Multi-step reaction with 2 steps
1: 82 percent / p-toluenesulfonic acid / 5 h / Heating
2: 87 percent / Al(i-PrO)3, cyclohexanone / toluene
View Scheme
Multi-step reaction with 2 steps
1: Reaktion ueber mehrere Stufen
2: diethyl ether
View Scheme
Multi-step reaction with 2 steps
1: sulfuric acid / 3 h / Reflux
2: aluminum isopropoxide / toluene; cyclohexanone / 3 h / 110 °C / Inert atmosphere
View Scheme
Pregnenolone
145-13-1

Pregnenolone

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: I2 / 1.5 h / Heating
2: methanol / 1 h / Heating
3: 70.62 percent / Al(i-PrO)3 / cyclohexanone; toluene / 4 h / Heating
View Scheme
Multi-step reaction with 3 steps
1: I2 / 1 h / Heating
2: methanol / 1 h / Heating
3: 1.) Al(i-PrO)3, 2.) Supercel, Darco KB / 1.) toluene, cyclohexanone, reflux, 1 h, 2.) toluene, cyclohexanone, water, 15 min
View Scheme
Multi-step reaction with 3 steps
1: iodine / 1.5 h / 90 °C / Inert atmosphere; Reflux
2: sodium methylate / 16 h / Inert atmosphere; Reflux
3: cyclohexanone; aluminum isopropoxide / toluene / 4 h / Reflux; Inert atmosphere
View Scheme
pregnenolone 21-pyridinium iodide
73672-02-3

pregnenolone 21-pyridinium iodide

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: methanol / 1 h / Heating
2: 70.62 percent / Al(i-PrO)3 / cyclohexanone; toluene / 4 h / Heating
View Scheme
Multi-step reaction with 2 steps
1: methanol / 1 h / Heating
2: 1.) Al(i-PrO)3, 2.) Supercel, Darco KB / 1.) toluene, cyclohexanone, reflux, 1 h, 2.) toluene, cyclohexanone, water, 15 min
View Scheme
Multi-step reaction with 2 steps
1: sodium methylate / 16 h / Inert atmosphere; Reflux
2: cyclohexanone; aluminum isopropoxide / toluene / 4 h / Reflux; Inert atmosphere
View Scheme
Pregnenolone acetate
1778-02-5

Pregnenolone acetate

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 1.) NaOBr, 2.) HCl / 1.) dioxane, water
2: 82 percent / p-toluenesulfonic acid / 5 h / Heating
3: 87 percent / Al(i-PrO)3, cyclohexanone / toluene
View Scheme
Multi-step reaction with 3 steps
1.1: sodium hypobromide / water; 1,4-dioxane / 3 h / 5 - 8 °C
1.2: 0.25 h / Reflux
1.3: 24 h / 5 - 90 °C
2.1: sulfuric acid / 3 h / Reflux
3.1: aluminum isopropoxide / toluene; cyclohexanone / 3 h / 110 °C / Inert atmosphere
View Scheme
21-Hydroxyprogesterone
64-85-7

21-Hydroxyprogesterone

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 68.3 percent / H2O2, 0.2N NaOH / hemin / methanol / 4 h / 20 °C
View Scheme
21-(Acetylthio)-17-hydroxy-4-pregnen-3,20-dion
113926-62-8

21-(Acetylthio)-17-hydroxy-4-pregnen-3,20-dion

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 73 percent / DMAP / bis-(2-methoxy-ethyl) ether / 17 h / Ambient temperature
2: 48 percent / NaN3 / 22 h / Ambient temperature
View Scheme
Multi-step reaction with 2 steps
1: 73 percent / DMAP / bis-(2-methoxy-ethyl) ether / 17 h / Ambient temperature
2: 8 percent / NaN3 / methanol / 1.5 h / 50 °C
View Scheme
methyl 3-oxo-5β-androstane-17β-carboxylate
50305-74-3

methyl 3-oxo-5β-androstane-17β-carboxylate

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: bromine
2: NaI; acetone / Erwaermen des Reaktionsprodukts mit Zink-Pulver und Aethanol
View Scheme
Multi-step reaction with 2 steps
1: bromine
2: NaI; acetone / Erwaermen des Reaktionsprodukts mit Zink-Pulver und Aethanol
View Scheme
methyl 5-androsten-3β-ol-17β-carboxylate
85541-82-8, 95119-09-8, 7254-03-7

methyl 5-androsten-3β-ol-17β-carboxylate

A

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

B

methyl 3-oxo-androst-4,6-diene-17β-carboxylate
116934-48-6

methyl 3-oxo-androst-4,6-diene-17β-carboxylate

Conditions
ConditionsYield
With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; 2,3-dicyano-5,6-dichloro-p-benzoquinone In dichloromethane at 0 - 20℃; Overall yield = 75 %;
Androstenedione
63-05-8

Androstenedione

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: toluene-4-sulfonic acid / tetrahydrofuran / 5 h / 5 °C / Inert atmosphere
2: n-butyllithium / 2-methyltetrahydrofuran / 6 h / -60 - -45 °C / Inert atmosphere
3: tert.-butylhydroperoxide; potassium iodide / methanol / 6.5 h / 20 °C / Reflux
View Scheme
3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

androst-4-en-3-one-17β-carboxylic acid
302-97-6

androst-4-en-3-one-17β-carboxylic acid

Conditions
ConditionsYield
With potassium hydroxide In methanol for 5h; Hydrolysis; Heating;100%
With potassium hydroxide In ethanol; water95%
With potassium hydroxide In methanol; water for 3h; Inert atmosphere; Reflux;89%
3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

Methyl 3-bromoandrosta-3,5-diene-17β-carboxylate
119169-85-6

Methyl 3-bromoandrosta-3,5-diene-17β-carboxylate

Conditions
ConditionsYield
With phosphorus tribromide In acetic acid for 21h; Ambient temperature;85%
3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

3β-hydroxy-androst-4-ene-17β-carboxylic acid methyl ester
150723-49-2

3β-hydroxy-androst-4-ene-17β-carboxylic acid methyl ester

Conditions
ConditionsYield
With diisopropoxytitanium(III) tetrahydroborate In dichloromethane at -20℃; for 0.5h;82%
With sodium tetrahydroborate
With sodium tetrahydroborate In methanol at 0℃; Reduction;
3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

methyl 3-oxo-androst-1,4-diene-17β-carboxylate
111497-46-2

methyl 3-oxo-androst-1,4-diene-17β-carboxylate

Conditions
ConditionsYield
With 2,3-dicyano-5,6-dichloro-p-benzoquinone In 1,4-dioxane for 48h; Reflux;81.2%
3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

methyl 3-oxo-androst-4,6-diene-17β-carboxylate
116934-48-6

methyl 3-oxo-androst-4,6-diene-17β-carboxylate

Conditions
ConditionsYield
With chloranil In chloroform; tert-butyl alcohol70%
3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

methyl iodide
74-88-4

methyl iodide

C23H34O3
1609387-14-5

C23H34O3

Conditions
ConditionsYield
Stage #1: 3-oxo-androst-4-ene-17β-carboxylic acid methyl ester With potassium tert-butylate In tetrahydrofuran at 0℃; for 0.0833333h; Inert atmosphere;
Stage #2: methyl iodide In tetrahydrofuran at 0℃; for 1h; Inert atmosphere;
63%
3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

A

androsta-3,5-diene-17β-carboxylic acid methyl ester
23737-99-7

androsta-3,5-diene-17β-carboxylic acid methyl ester

B

3β-hydroxy-androst-4-ene-17β-carboxylic acid methyl ester
150723-49-2

3β-hydroxy-androst-4-ene-17β-carboxylic acid methyl ester

Conditions
ConditionsYield
With sodium tetrahydroborate
3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

2ξ,6ξ-dibromo-3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
423166-44-3

2ξ,6ξ-dibromo-3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

Conditions
ConditionsYield
With bromine
3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

A

methyl 3β-hydroxy-5α-androstane-17β-carboxylate
10002-85-4

methyl 3β-hydroxy-5α-androstane-17β-carboxylate

B

3α-hydroxy-5β-androstan-17β-carboxylic acid methyl ester
74464-95-2

3α-hydroxy-5β-androstan-17β-carboxylic acid methyl ester

Conditions
ConditionsYield
With methanol; palladium anschliessend Hydrierung an Platin in Methanol und Essigsaeure; Isolierung von Digitonin;
With methanol; palladium anschliessend Hydrierung an Platin in Methanol und Essigsaeure;
3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

3α-acetoxy-5β-androstane-17β-carboxylic acid methyl ester
74497-93-1

3α-acetoxy-5β-androstane-17β-carboxylic acid methyl ester

Conditions
ConditionsYield
With ethanol; alkaline solution; nickel Hydrogenation.Behandlung der neutralen Anteile des Reaktionsprodukts mit Acetanhydrid und Pyridin;
3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

17β-methoxycarbonyl-5-oxo-3,5-seco-A-nor-androstan-3-oic acid
92472-33-8

17β-methoxycarbonyl-5-oxo-3,5-seco-A-nor-androstan-3-oic acid

Conditions
ConditionsYield
With chloroform; ozone Behandeln des Reaktionsprodukts mit wss. Essigsaeure und anschliessendes Erwaermen mit Zink;
With potassium permanganate; sodium periodate; sodium carbonate In water; tert-butyl alcohol Heating;
3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

acetic anhydride
108-24-7

acetic anhydride

acetyl chloride
75-36-5

acetyl chloride

3-acetoxy-androstadiene-(3.5)-carboxylic acid-(17β)-methyl ester
911663-11-1

3-acetoxy-androstadiene-(3.5)-carboxylic acid-(17β)-methyl ester

Conditions
ConditionsYield
at 100 - 140℃;
Methyl formate
107-31-3

Methyl formate

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

(8S,9S,10R,13S,14S,17S)-2-[1-Hydroxy-meth-(Z)-ylidene]-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-17-carboxylic acid methyl ester
138091-50-6

(8S,9S,10R,13S,14S,17S)-2-[1-Hydroxy-meth-(Z)-ylidene]-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-17-carboxylic acid methyl ester

Conditions
ConditionsYield
With sodium methylate
3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

17β-androstane-4-ene-3-keto-17-formaldehyde
6247-91-2

17β-androstane-4-ene-3-keto-17-formaldehyde

Conditions
ConditionsYield
With lithium aluminium tetrahydride 1.) THF, room temperature, 1 h, 0 deg C; 2.) oxidation; Yield given. Multistep reaction;
3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

17β-carbomethoxyandrost-4-ene
119169-67-4

17β-carbomethoxyandrost-4-ene

Conditions
ConditionsYield
With sodium tetrahydroborate; acetic acid; trifluoroacetic acid In dichloromethane; acetonitrile at 20℃; for 2h; Reduction;
methanol
67-56-1

methanol

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester
2681-55-2

3-oxo-androst-4-ene-17β-carboxylic acid methyl ester

palladium

palladium

A

methyl 3β-hydroxy-5α-androstane-17β-carboxylate
10002-85-4

methyl 3β-hydroxy-5α-androstane-17β-carboxylate

B

3α-hydroxy-5β-androstan-17β-carboxylic acid methyl ester
74464-95-2

3α-hydroxy-5β-androstan-17β-carboxylic acid methyl ester

Conditions
ConditionsYield
anschliessend Hydrierung an Platin in Essigsaeure enthaltendem Methanol;

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