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AllyChem Co., Ltd., Dalian, China(BBChem)

AllyChem Co., Ltd., Dalian, China was founded in 2004 with a registered capital of 66 million yuan and is located in dagushan peninsula chemical industrial park, jinzhou new district, dalian.It is a pharmaceutical intermediates based on the research

4-Pyrazoleboronic Acid Pinacol Ester AC131017 Strongly Recommanded

Cas:269410-08-4

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

4-Pyrazoleboronic acid pinacol ester

Cas:269410-08-4

Min.Order:1 Kilogram

Negotiable

Type:Other

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Suzhou SuKaiLu Chemical Technology Co., Ltd.

Our Company main product 一:suzuki reaction customization 二:Boronic acid derivative ①:phenylboronic acid derivative ②:Phenylboronic acid pinacol ester derivative ③:Potassium phenyltrifluoroborate derivative ④:Phenylboronic acid MIDA ester derivative

4-Pyrazoleboronic acid pinacol ester

Cas:269410-08-4

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

Pyrazole-4-boronic acid pinacol ester Manufacturer/High quality/Best price/In stock

Cas:269410-08-4

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Jinan Finer Chemical Co., Ltd

Product description: Product name Pyrazole-4-boronic acid pinacol ester CAS number 269410-08-4 Assay ≥99% Appearance Off-white to tan powder Capacity 200mt/year Application P

Pyrazole-4-boronic acid pinacol ester

Cas:269410-08-4

Min.Order:10 Gram

FOB Price: $12.0

Type:Lab/Research institutions

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Hangzhou Think Chemical Co. Ltd

Pyrazole-4-boronic acid pinacol ester CAS No.:269410-08-4 Name: Pyrazole-4-boronic acid pinacol ester Synonyms: 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole Molecular Structure

High purity Pyrazole-4-boronic acid pinacol ester CAS No.:269410-08-4

Cas:269410-08-4

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Other

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off white powder Storage:Sealed, dry, microtherm , avoid light and smell Package:According to the demand of customer Application:Pharmaceutical intermediates Transportation:by air or by sea Port:shanghai

4-Pyrazoleboronic acid pinacol ester

Cas:269410-08-4

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 4,4,5,5-Tetramethyl-2-(1H-Pyrazol-4-Yl)-1,3,2-Diox

Cas:269410-08-4

Min.Order:1

Negotiable

Type:Other

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price OLED 99% 269410-08-4 4-Pyrazoleboronic acid pinacol ester Manufacturer

Cas:269410-08-4

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

Pyrazol-4-Boronic Acid Pineapple Ester

Cas:269410-08-4

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

CHemwill -- Pyrazole-4-boronic acid pinacol ester

Cas:269410-08-4

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

high quality Pyrazole-4-boronic acid pinacol ester

Cas:269410-08-4

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

4-Pyrazoleboronic acid pinacol ester

Cas:269410-08-4

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 269410-08-4 with best quality

Cas:269410-08-4

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Shijiazhuang Sdyano Fine Chemical Co., Ltd

1. Best prices with satisfied quality; 2. It's clients' right to choose the package's Courier (EMS, DHL, FedEx, UPS); 3.It's clients' right to choose the packing way for his produccts from many recent effective packing ways;

Pyrazole-4-boronic acid pinacol ester

Cas:269410-08-4

Min.Order:0 Metric Ton

Negotiable

Type:Trading Company

inquiry

Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developmen

4-Pyrazoleboronic acid pinacol ester

Cas:269410-08-4

Min.Order:1 Kilogram

FOB Price: $2.0 / 5.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1H-Pyrazole,4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)- 269410-08-4

Cas:269410-08-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Pyrazole-4-boronic acid pinacol ester

Cas:269410-08-4

Min.Order:1 Kilogram

FOB Price: $76.0 / 85.0

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

4-Pyrazoleboronic acid pinacol ester CAS:269410-08-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high qua

4-Pyrazoleboronic acid pinacol ester CAS:269410-08-4

Cas:269410-08-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:269410-08-4

Cas:269410-08-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

4,4,5,5-Tetramethyl-2-(1H-pyrazol-4-yl)-1,3,2-diox

Cas:269410-08-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Triumph International Development Limilted

Triumph has the complete production of G- KG - MT service chain,we can make the new technology into productivity quickly in the research and development of new products. Main Service 1.Own made fine chemical products 2.Out sourcing and qua

4-Pyrazoleboronic acid pinacol ester

Cas:269410-08-4

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Pyrazole-4-boronic acid pinacol ester

Cas:269410-08-4

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

Cas:269410-08-4

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

Cas:269410-08-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

Featured products Pyrazole-4-boronic acid pinacol ester

Cas:269410-08-4

Min.Order:100 Gram

Negotiable

Type:Other

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Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

Pyrazole-4-boronic acid pinacol ester/High quality/Best price

Cas:269410-08-4

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

4-Pyrazoleboronic acid pinacol ester

Cas:269410-08-4

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazoleAppearance:powder Storage:store in a cool dry place and keep away from strong Package:according to customers' requirements Application:in research Transportation:By air(EMS or EUB or FedEx or

4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

Cas:269410-08-4

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole,min.97%

Cas:269410-08-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

1-(1-ethoxyethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
1029716-44-6

1-(1-ethoxyethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

Conditions
ConditionsYield
With hydrogenchloride; 2,3-dimethyl-2,3-butane diol In water at 10 - 25℃; for 4.083h;94%
With hydrogenchloride; 2,3-dimethyl-2,3-butane diol In tert-butyl methyl ether; 1,2-dichloro-ethane at 0 - 20℃; Large scale;77.3%
With hydrogenchloride; 2,3-dimethyl-2,3-butane diol In tert-butyl methyl ether; 1,2-dichloro-ethane at 0 - 20℃; Large scale;77.3%
4-bromo-1H-pyrazole
2075-45-8

4-bromo-1H-pyrazole

bis(pinacol)diborane
73183-34-3

bis(pinacol)diborane

pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; tetrabutylammomium bromide; potassium carbonate In 1,4-dioxane for 12h; Inert atmosphere; Reflux;94%
With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; potassium acetate In N,N-dimethyl-formamide at 100℃;25%
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate In 1,4-dioxane at 80℃; Inert atmosphere;
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate In 1,4-dioxane at 80℃; Miyaura Borylation Reaction; Inert atmosphere;
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate In 1,4-dioxane at 80℃; Miyaura Borylation Reaction; Inert atmosphere;
NH-pyrazole
288-13-1

NH-pyrazole

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane
25015-63-8

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

Conditions
ConditionsYield
With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; 3,4,7,8-Tetramethyl-o-phenanthrolin In tetrahydrofuran at 80℃; for 4h; Inert atmosphere; Glovebox; regioselective reaction;88%
With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; 3,4,7,8-Tetramethyl-o-phenanthrolin In tetrahydrofuran at 80℃; for 4h; Schlenk technique; Inert atmosphere;67%
4-chloro-1H-pyrazole
15878-00-9

4-chloro-1H-pyrazole

bis(pinacol)diborane
73183-34-3

bis(pinacol)diborane

pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

Conditions
ConditionsYield
With potassium phosphate tribasic heptahydrate; chloro(2-dicyclohexylphosphino-2’,4’,6’-triisopropyl-1,1‘-biphenyl)[2-(2’-amino-1,1‘-biphenyl’)]palladium(II); XPhos In ethanol at 20℃; for 0.5h;88%
tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole-1-carboxylate
552846-17-0

tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole-1-carboxylate

pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

Conditions
ConditionsYield
at 180℃;80.2%
at 180℃; for 0.0833333h;72%
4-iodo-1H-pyrazole-1-carboxylic acid tert-butyl ester
121669-70-3

4-iodo-1H-pyrazole-1-carboxylic acid tert-butyl ester

2-dimethylamino-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
557087-01-1

2-dimethylamino-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

Conditions
ConditionsYield
With iPrBu2MgLi In 2-methyltetrahydrofuran at -20 - -10℃; Large scale;79%
2-dimethylamino-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
557087-01-1

2-dimethylamino-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

4-bromopyrazole-1-carboxylic acid tert-butyl ester
1150271-23-0

4-bromopyrazole-1-carboxylic acid tert-butyl ester

pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

Conditions
ConditionsYield
With n-Bu3MgLi In tetrahydrofuran at -20 - -10℃; Large scale;76%
NH-pyrazole
288-13-1

NH-pyrazole

bis(pinacol)diborane
73183-34-3

bis(pinacol)diborane

pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

Conditions
ConditionsYield
With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; 3,4,7,8-Tetramethyl-o-phenanthrolin In tetrahydrofuran at 80℃; for 21h; Inert atmosphere; Glovebox;56%
2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
61676-62-8

2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

1-trimethylsilyl-4-iodopyrazole

1-trimethylsilyl-4-iodopyrazole

pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

Conditions
ConditionsYield
Stage #1: 4-iodo-1-trimethylsilylpyrazole With isopropylmagnesium chloride In tetrahydrofuran at -6 - 0℃; Inert atmosphere;
Stage #2: 2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane In tetrahydrofuran at 0 - 20℃; Inert atmosphere;
54.8%
Stage #1: 4-iodo-1-trimethylsilylpyrazole With isopropylmagnesium chloride In tetrahydrofuran at -6 - 0℃; for 0.166667h; Inert atmosphere;
Stage #2: 2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane In tetrahydrofuran at 0 - 20℃; for 2h; Inert atmosphere;
Stage #3: With water; ammonium chloride In tetrahydrofuran at -6 - 0℃;
54.8%
Stage #1: 4-iodo-1-trimethylsilylpyrazole With isopropylmagnesium chloride In tetrahydrofuran at -6 - 0℃; for 0.166667h;
Stage #2: 2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane In tetrahydrofuran at 0 - 20℃; for 2.17h;
54.8%
4-iodopyrazole
3469-69-0

4-iodopyrazole

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane
25015-63-8

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

Conditions
ConditionsYield
Stage #1: With triethylamine; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride In 1,4-dioxane at 80℃; for 18h;
Stage #2: 4-iodopyrazole; 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane In 1,4-dioxane at 80℃; for 18h;
4-iodopyrazole
3469-69-0

4-iodopyrazole

2-methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
1195-66-0

2-methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

Conditions
ConditionsYield
Stage #1: 4-iodopyrazole With isopropylmagnesium chloride In tetrahydrofuran at -10℃; for 2.5h; Inert atmosphere;
Stage #2: 2-methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane In tetrahydrofuran at 20℃; for 2h; Inert atmosphere;
bis(pinacol)diborane
73183-34-3

bis(pinacol)diborane

pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / ethanol / 16 h / Inert atmosphere; Reflux
2: 180 °C
View Scheme
pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

3-[(5-bromo-[1,2,4]triazolo[1,5-a]pyrazin-8-yl)-tert-butoxycarbonyl-amino]benzoic acid ethyl ester
959756-24-2

3-[(5-bromo-[1,2,4]triazolo[1,5-a]pyrazin-8-yl)-tert-butoxycarbonyl-amino]benzoic acid ethyl ester

3-{tert-butoxycarbonyl-[5-(1H-pyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyrazin-8-yl]-amino}benzoic acid ethyl ester
959756-25-3

3-{tert-butoxycarbonyl-[5-(1H-pyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyrazin-8-yl]-amino}benzoic acid ethyl ester

Conditions
ConditionsYield
With potassium carbonate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2 In 1,4-dioxane; water at 115℃; for 0.416667h;100%
glycidyl methyl ether
930-37-0

glycidyl methyl ether

pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

1-methoxy-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propan-2-ol
1000801-77-3

1-methoxy-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propan-2-ol

Conditions
ConditionsYield
at 98℃; for 4h;100%
pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

3-(cyanomethylene)azetidine-1-carboxylic acid tert-butyl ester
1153949-11-1

3-(cyanomethylene)azetidine-1-carboxylic acid tert-butyl ester

tert-butyl 3-(cyanomethyl)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)azetidine-1-carboxylate
1153949-15-5

tert-butyl 3-(cyanomethyl)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)azetidine-1-carboxylate

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In acetonitrile at 50℃;100%
With 1,8-diazabicyclo[5.4.0]undec-7-ene In isopropyl alcohol Reflux; Inert atmosphere;90.5%
With 1,8-diazabicyclo[5.4.0]undec-7-ene In isopropyl alcohol Reflux;90.5%
2-iodo-propane
75-30-9

2-iodo-propane

pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

1-isopropylpyrazole-4-boronic acid pinacol ester
879487-10-2

1-isopropylpyrazole-4-boronic acid pinacol ester

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 90℃; for 16h; Inert atmosphere;100%
With caesium carbonate In N,N-dimethyl-formamide at 90℃; for 16h;61.72%
With caesium carbonate In N,N-dimethyl-formamide at 0 - 20℃;57%
pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

3-{[tert-butyl(dimethyl)silyl]oxy}-2-fluoropropyltrifluoromethanesulfonate
1182357-90-9

3-{[tert-butyl(dimethyl)silyl]oxy}-2-fluoropropyltrifluoromethanesulfonate

(3-{[tert-butyl(dimethyl)silyl]oxy}-2-fluoropropyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
1309960-93-7

(3-{[tert-butyl(dimethyl)silyl]oxy}-2-fluoropropyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

Conditions
ConditionsYield
Stage #1: pyrazole-4-boronic acid pinacol ester With sodium hydride In N,N-dimethyl-formamide; mineral oil at 20℃; for 0.5h; Inert atmosphere;
Stage #2: 3-{[tert-butyl(dimethyl)silyl]oxy}-2-fluoropropyltrifluoromethanesulfonate In N,N-dimethyl-formamide; mineral oil for 0.333333h; Inert atmosphere;
100%
pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

2-chloroethyl methyl ether
627-42-9

2-chloroethyl methyl ether

1-(2-methoxyethyl)-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
847818-71-7

1-(2-methoxyethyl)-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 160℃; for 0.5h; Microwave irradiation;100%
With caesium carbonate In N,N-dimethyl-formamide at 160℃; for 0.5h; Microwave irradiation;100%
With caesium carbonate In N,N-dimethyl-formamide at 160℃; for 0.5h; microwave irradiation;72%
With caesium carbonate In N,N-dimethyl-formamide at 160℃; for 0.5h; Microwave irradiation;72%
bromoacetopyrrolidine
90892-09-4

bromoacetopyrrolidine

pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

1-(pyrrolidin-1-yl)-2-(4-(4,4,5,5-tetramethyl-1,3,2- dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethan-1-one
1534350-51-0

1-(pyrrolidin-1-yl)-2-(4-(4,4,5,5-tetramethyl-1,3,2- dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethan-1-one

Conditions
ConditionsYield
In acetonitrile at 20℃;100%
pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

2-(2,2,2-trifluoroethyl)oxirane
407-12-5

2-(2,2,2-trifluoroethyl)oxirane

4,4,4-trifluoro-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)butan-2-ol

4,4,4-trifluoro-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)butan-2-ol

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 80℃;100%
pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

(2R,5R)-tert-butyl 5-methyl-2-(((methylsulfonyl)oxy)methyl)morpholine-4-carboxylate

(2R,5R)-tert-butyl 5-methyl-2-(((methylsulfonyl)oxy)methyl)morpholine-4-carboxylate

tert-butyl (2R,5R)-5-methyl-2-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)methyl)morpholine-4-carboxylate

tert-butyl (2R,5R)-5-methyl-2-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)methyl)morpholine-4-carboxylate

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 20℃; for 24h;100%
pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

tert-butyl ((1S,3S,4R)-3-benzyl-4-(3-(hydroxymethyl)phenoxy)cyclopentyl)carbamate

tert-butyl ((1S,3S,4R)-3-benzyl-4-(3-(hydroxymethyl)phenoxy)cyclopentyl)carbamate

tert-butyl ((1S,3S,4R)-3-benzyl-4-(3-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)methyl)phenoxy)cyclopentyl)carbamate

tert-butyl ((1S,3S,4R)-3-benzyl-4-(3-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)methyl)phenoxy)cyclopentyl)carbamate

Conditions
ConditionsYield
With tributylphosphine; diamide In toluene at 20℃; Mitsunobu Displacement; Sonication;100%
With tributylphosphine; diamide In toluene at 20℃; Inert atmosphere;100%
pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

3-hydroxylmethyl oxetane

3-hydroxylmethyl oxetane

1-(oxetan-3-ylmethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
1578484-07-7

1-(oxetan-3-ylmethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

Conditions
ConditionsYield
With cyanomethylenetributyl-phosphorane In 1,4-dioxane at 150℃; for 0.75h; Microwave irradiation;100%
pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole-1-carboxylate
552846-17-0

tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole-1-carboxylate

Conditions
ConditionsYield
With dmap In N,N-dimethyl-formamide at 0 - 20℃;99%
With dmap; N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃;99.68%
With dmap In dichloromethane at 20℃; for 4h;85%
pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

1-Bromo-2-chloroethane
107-04-0

1-Bromo-2-chloroethane

1-(2-chloroethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
877149-79-6

1-(2-chloroethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

Conditions
ConditionsYield
With caesium carbonate In acetonitrile at 70℃; for 6h;99%
With caesium carbonate In acetonitrile at 62℃; for 4h;90%
With caesium carbonate In acetonitrile at 75℃; for 5h;88%
With caesium carbonate In acetonitrile at 75℃; for 5h;
pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

4-(bromomethyl)-1-methyl-1H-pyrazole hydrobromide

4-(bromomethyl)-1-methyl-1H-pyrazole hydrobromide

1-methyl-4-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)methyl)-1H-pyrazole

1-methyl-4-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)methyl)-1H-pyrazole

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 60℃; for 1h;99%
pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

2-nitrophenyl bromide
577-19-5

2-nitrophenyl bromide

4-(2-nitrophenyl)pyrazole

4-(2-nitrophenyl)pyrazole

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; tetrabutylammomium bromide; potassium carbonate In N,N-dimethyl-formamide98.5%
pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

bromobenzene
108-86-1

bromobenzene

4-phenyl-1H-pyrazole
10199-68-5

4-phenyl-1H-pyrazole

Conditions
ConditionsYield
With tetrabutylammomium bromide; potassium carbonate; palladium dichloride In N,N-dimethyl-formamide at 130℃; for 16h; Inert atmosphere;98%
pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

tert-butyl (3-bromo-1-((1s,4s)-4-((1-methyl-6-oxo-1,6-dihydropyridazin-3-yl)oxy)cyclohexyl)-1H-pyrazolo[4,3-c]pyridin-6-yl)(methyl)carbamate

tert-butyl (3-bromo-1-((1s,4s)-4-((1-methyl-6-oxo-1,6-dihydropyridazin-3-yl)oxy)cyclohexyl)-1H-pyrazolo[4,3-c]pyridin-6-yl)(methyl)carbamate

tert-butyl methyl(1-((1s,4s)-4-((1-methyl-6-oxo-1,6-dihydropyridazin-3-yl)oxy)cyclohexyl)-3-(1H-pyrazol-4-yl)-1H-pyrazolo[4,3-c]pyridin-6-yl)carbamate

tert-butyl methyl(1-((1s,4s)-4-((1-methyl-6-oxo-1,6-dihydropyridazin-3-yl)oxy)cyclohexyl)-3-(1H-pyrazol-4-yl)-1H-pyrazolo[4,3-c]pyridin-6-yl)carbamate

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); sodium carbonate In 1,4-dioxane at 90℃; for 12h; Inert atmosphere; Sealed tube;98%
pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

ethyl vinyl ether
109-92-2

ethyl vinyl ether

1-(1-ethoxyethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
1029716-44-6

1-(1-ethoxyethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

Conditions
ConditionsYield
Stage #1: pyrazole-4-boronic acid pinacol ester; ethyl vinyl ether With hydrogenchloride In 1,4-dioxane; toluene at 35 - 40℃; Inert atmosphere;
Stage #2: With sodium hydrogencarbonate In 1,4-dioxane; toluene for 1h; Product distribution / selectivity;
97.3%
With hydrogenchloride In 1,4-dioxane; toluene at 35℃; Inert atmosphere;90%
In toluene at 35℃; for 13h; Inert atmosphere;
pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

Methyl 2-bromobutyrate
3196-15-4, 69043-96-5

Methyl 2-bromobutyrate

methyl 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)butanoate

methyl 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)butanoate

Conditions
ConditionsYield
With caesium carbonate In Petroleum ether97%
pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

(2-chloroethyl)dimethylamine hydrochloride
4584-46-7

(2-chloroethyl)dimethylamine hydrochloride

N,N-dimethyl-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethan-1-amine
877149-80-9

N,N-dimethyl-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethan-1-amine

Conditions
ConditionsYield
With caesium carbonate In acetonitrile for 5h; Reflux;95%
With caesium carbonate In acetonitrile at 90℃;88%
With caesium carbonate In N,N-dimethyl-formamide at 0 - 20℃; for 72.5h;66%
pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

ethyl 3-(2-(((trifluoromethyl)sulfonyl)oxy)naphthalene-1-yl)propanoate
1417620-53-1

ethyl 3-(2-(((trifluoromethyl)sulfonyl)oxy)naphthalene-1-yl)propanoate

ethyl 3-(2-(1H-pyrazol-4-yl)naphthalen-1-yl)propanoate
1426148-40-4

ethyl 3-(2-(1H-pyrazol-4-yl)naphthalen-1-yl)propanoate

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate In 1,4-dioxane for 4h; Suzuki-Miyaura Coupling; Reflux;95%
pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

8-bromo-N-tert-butyl-1-(3,5-dichlorophenyl)-7-methoxy-N-methyl-1,4-dihydrochromeno[4,3-c]pyrazole-3-carboxamide

8-bromo-N-tert-butyl-1-(3,5-dichlorophenyl)-7-methoxy-N-methyl-1,4-dihydrochromeno[4,3-c]pyrazole-3-carboxamide

N-tert-butyl-1-(3,5-dichlorophenyl)-7-methoxy-N-methyl-8-(1H-pyrazol-4-yl)-1,4-dihydrochromeno[4,3-c]pyrazole-3-carboxamide

N-tert-butyl-1-(3,5-dichlorophenyl)-7-methoxy-N-methyl-8-(1H-pyrazol-4-yl)-1,4-dihydrochromeno[4,3-c]pyrazole-3-carboxamide

Conditions
ConditionsYield
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; caesium carbonate In 1,4-dioxane; water at 90℃; for 1h; Inert atmosphere; Microwave irradiation;95%
pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

allyl bromide
106-95-6

allyl bromide

1-allyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
1000801-78-4

1-allyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

Conditions
ConditionsYield
With sodium hexamethyldisilazane In tetrahydrofuran at 70℃;94%
With caesium carbonate In N,N-dimethyl-formamide at 100℃; for 1h; Microwave irradiation;39%
pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

2-(bromomethyl)benzonitrile
22115-41-9

2-(bromomethyl)benzonitrile

C17H20BN3O2
930596-18-2

C17H20BN3O2

Conditions
ConditionsYield
With potassium carbonate In acetonitrile for 72h; Heating / reflux;94%
3,4-dihydro-2H-pyran
110-87-2

3,4-dihydro-2H-pyran

pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

1-(tetrahydro-2H-pyran-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
1003846-21-6

1-(tetrahydro-2H-pyran-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

Conditions
ConditionsYield
With trifluoroacetic acid In toluene at 90℃; for 2h;94%
With toluene-4-sulfonic acid In dichloromethane at 20℃; for 4h;90%
With toluene-4-sulfonic acid In dichloromethane at 20℃; for 4h;90%
pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

p-methoxybenzyl chloride
824-94-2

p-methoxybenzyl chloride

1-(4-methoxybenzyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
1105039-88-0

1-(4-methoxybenzyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 80℃; for 5h;94%
With potassium carbonate In acetonitrile at 80℃; for 5h;91%
With potassium carbonate In acetonitrile at 60℃; for 15h;73.3%
With potassium carbonate In acetonitrile at 80℃; for 5h;
With caesium carbonate In acetonitrile for 4h; Reflux;
pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

3-chloro-2-methylpropan-2-ol
558-42-9

3-chloro-2-methylpropan-2-ol

2-methyl-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propan-2-ol

2-methyl-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propan-2-ol

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 160℃; for 2.5h; Microwave irradiation;94%
pyrazole-4-boronic acid pinacol ester
269410-08-4

pyrazole-4-boronic acid pinacol ester

tert-butyl (S)-3-((4-((1R,3R)-3-methyl-2-(2,2,2-trifluoroethyl)-6-(trifluoromethanesulfonyloxy)-1,2,3,4-tetrahydroisoquinolin-1-yl)phenyl)amino)pyrrolidin-1-carboxylate

tert-butyl (S)-3-((4-((1R,3R)-3-methyl-2-(2,2,2-trifluoroethyl)-6-(trifluoromethanesulfonyloxy)-1,2,3,4-tetrahydroisoquinolin-1-yl)phenyl)amino)pyrrolidin-1-carboxylate

tert-butyl (S)-3-((4-((1R,3R)-3-methyl-6-(1H-pyrazol-4-yl)-2-(2,2,2-trifluoroethyl)-1,2,3,4-tetrahydroisoquinolin-1-yl)phenyl)amino)pyrrolidin-1-carboxylate

tert-butyl (S)-3-((4-((1R,3R)-3-methyl-6-(1H-pyrazol-4-yl)-2-(2,2,2-trifluoroethyl)-1,2,3,4-tetrahydroisoquinolin-1-yl)phenyl)amino)pyrrolidin-1-carboxylate

Conditions
ConditionsYield
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate In 1,4-dioxane; water at 80℃; for 16h; Inert atmosphere;94%

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