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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

1-(2-Amino-5-hydroxyphenyl)propan-1-one

Cas:35364-15-9

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

1-(2-Amino-5-hydroxyphenyl)propan-1-one CAS:35364-15-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high

1-(2-Amino-5-hydroxyphenyl)propan-1-one CAS:35364-15-9

Cas:35364-15-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1-Propanone,1-(2-amino-5-hydroxyphenyl)-

Cas:35364-15-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

1-Propanone,1-(2-amino-5-hydroxyphenyl)-

Cas:35364-15-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

1-PROPANONE,1-(2-AMINO-5-HYDROXYPHENYL)-

Cas:35364-15-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

1-Propanone,1-(2-amino-5-hydroxyphenyl)-

Cas:35364-15-9

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

1-(2-Amino-5-hydroxyphenyl)propan-1-one

Cas:35364-15-9

Min.Order:1 Milligram

Negotiable

Type:Trading Company

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Henan Tianfu Chemical Co., Ltd.

Our advantage:Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientif

TIANFU-CHEM CAS NO.35364-15-9 1-(2-Amino-5-hydroxyphenyl)propan-1-one

Cas:35364-15-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

1-Propanone, 1-(2-amino-5-hydroxyphenyl)-

Cas:35364-15-9

Min.Order:0

Negotiable

Type:Other

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM is one of China's leading providers of integrated fine chemical services including offering, research and development, Custom manufacturing business, as well as other Value-added customer services, for diversified range products of chemicals

1-(2-Amino-5-hydroxyphenyl)propan-1-one

Cas:35364-15-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

1-(2-Amino-5-hydroxyphenyl)propan-1-one

Cas:35364-15-9

Min.Order:0

Negotiable

Type:Manufacturers

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Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

1-Propanone,1-(2-amino-5-hydroxyphenyl)-

Cas:35364-15-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Guangdong Juda Chemical Industrial Co.,Limited

Factory supply high purity low priceAppearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China

1-(2-Amino-5-hydroxyphenyl)propan-1-one CAS No.35364-15-9

Cas:35364-15-9

Min.Order:0

Negotiable

Type:Trading Company

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DB BIOTECH CO., LTD

best seller Application:API

1-(2-Amino-5-hydroxyphenyl)propan-1-one

Cas:35364-15-9

Min.Order:0

Negotiable

Type:Trading Company

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Hangzhou Fandachem Co.,Ltd

1-(2-amino-5-hydroxyphenyl)propan-1-oneAppearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:pharmaceutical intermediate Transportation:by air, by sea, by express

1-(2-amino-5-hydroxyphenyl)propan-1-one

Cas:35364-15-9

Min.Order:0

Negotiable

Type:Other

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Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

1-(2-Amino-5-hydroxyphenyl)propan-1-one

Cas:35364-15-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Shanghai Terui OP New Material Technology Co., Ltd.

The factory supplies Application:manufacturing supplies

1-Propanone,1-(2-amino-5-hydroxyphenyl)-

Cas:35364-15-9

Min.Order:0

Negotiable

Type:Trading Company

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Shanghai Chinqesen Biotechnology Co., Ltd.

Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen

35364-15-9

Cas:35364-15-9

Min.Order:0

Negotiable

Type:Trading Company

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Hebei Muhuang Technology Co., Ltd

best seller Application:API

1-(2-Amino-5-hydroxyphenyl)propan-1-one

Cas:35364-15-9

Min.Order:0

Negotiable

Type:Trading Company

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Changzhou Extraordinary Pharmatech co.,LTD

Changzhou Extraordinary Pharmatech co., LTD. As a leading chemical manufacturer and supplier in China.DAS authentication is passed.We can provide the popular precursor chemicals, we have our own strong R & D team, have our own laboratories and fa

1-(2-Amino-5-hydroxyphenyl)propan-1-one

Cas:35364-15-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Jiangxi Meisi Kangte Biotechnology Pharmaceutical Co., Ltd.

1-Propanone,1-(2-amino-5-hydroxyphenyl)- 【CAS Registry number】 35364-15-9 【Synonyms】 1-(2-Amino-5-hydroxyphenyl)propan-1-one 2'-Amino-5'-hydroxypropiophenone 【Molecular Formula】 C13H13NO5

1-(2-amino-5-hydroxyphenyl)propan-1-one 35364-15-9

Cas:35364-15-9

Min.Order:5 Kilogram

Negotiable

Type:Trading Company

inquiry

Shanghai united Scientific Co.,Ltd.

United Scientific Company Located in Shanghai of China , is a competitive player in the global specialty and fine chemical market. Fenghua has both the expertise and flexibility to produce a wide range of chemicals. Focusing on developing the innovat

1-Propanone,1-(2-amino-5-hydroxyphenyl)-

Cas:35364-15-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chungking Joyinchem Co., Ltd.

Joyinchem have been committed to chemical supply for several years and have built good cooperation records with multinational chemical corporations and importers from all over the world. Our services include:-Spot goods-Contract manufacturing-Custom

1-Propanone,1-(2-amino-5-hydroxyphenyl)-

Cas:35364-15-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Nanjing Raymon Biotech Co., Ltd.

1-Propanone,1-(2-amino-5-hydroxyphenyl)-Appearance:Off white to slight yellow solid Storage:Store in dry and cool condition Package:25kg or according to cutomer's demand Application:Chemical research/Pharmaceutical intermediates Transportation:By Sea

1-Propanone,1-(2-amino-5-hydroxyphenyl)-

Cas:35364-15-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synova( Tianjin ) Chemical Technology Co,.Ltd

The company have effective management team, professional technical R & D personnel, the service spirit of customer oriented. We have long-term cooperation with famous domestic manufacturer, and excellent customer resources overseas. We are skilled in

1-(2-Amino-5-hydroxyphenyl)propan-1-one

Cas:35364-15-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Ruishun Trade Co.,Ltd

Supply top quality products with a reasonable price Application:api

35364-15-9

Cas:35364-15-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Beyond Pharmaceutical Co., Ltd

Used in medicine Application:Used in medicine

1-(2-amino-5-hydroxyphenyl)propan-1-one

Cas:35364-15-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemical Co.Ltd

1-Propanone,1-(2-amino-5-hydroxyphenyl)-Appearance:Off white to slight yellow solid Storage:Stored in shaded, cool and dry places Package:1L 5L 10L 25L bottle Application:pharma intermediate Transportation:Handle with cares to avoid damaging the pack

1-Propanone,1-(2-amino-5-hydroxyphenyl)-

Cas:35364-15-9

Min.Order:0

Negotiable

Type:Trading Company

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Avra Laboratories Pvt. Ltd.

99% purity

2-Amino-5-Hydroxy propiophenone

Cas:35364-15-9

Min.Order:0

Negotiable

Type:Trading Company

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Synthetic route

1-(5-hydroxy-2-nitrophenyl)propan-1-one
453518-19-9

1-(5-hydroxy-2-nitrophenyl)propan-1-one

2'-amino-5'-hydroxypropiophenone
35364-15-9

2'-amino-5'-hydroxypropiophenone

Conditions
ConditionsYield
With sodium dithionite; water; sodium carbonate at 20℃; for 1h;92%
With methanol; sodium dithionite; water; sodium carbonate at 0 - 20℃; for 3h;
With sodium dithionite; water; sodium carbonate In methanol at 0 - 20℃; for 3h;
With sodium dithionite; sodium carbonate In methanol at 0 - 30℃; for 1h;3.6 g
1-(5-benzyloxy-2-nitrophenol)-2-propen-1-one
453518-18-8

1-(5-benzyloxy-2-nitrophenol)-2-propen-1-one

2'-amino-5'-hydroxypropiophenone
35364-15-9

2'-amino-5'-hydroxypropiophenone

Conditions
ConditionsYield
With hydrogen; palladium 10% on activated carbon In ethyl acetate at 0 - 25℃; for 13h;84%
1-(5-benzyloxy-2-nitrophenol)-2-propen-1-one
453518-18-8

1-(5-benzyloxy-2-nitrophenol)-2-propen-1-one

A

2'-amino-5'-hydroxypropiophenone
35364-15-9

2'-amino-5'-hydroxypropiophenone

B

1-(5-hydroxy-2-nitrophenyl)propan-1-one
453518-19-9

1-(5-hydroxy-2-nitrophenyl)propan-1-one

Conditions
ConditionsYield
With hydrogen; palladium 10% on activated carbon In ethyl acetate at 0 - 25℃;A 14%
B 0%
ethyl bromide
74-96-4

ethyl bromide

2-amino-5-methoxybenzonitrile
23842-82-2

2-amino-5-methoxybenzonitrile

2'-amino-5'-hydroxypropiophenone
35364-15-9

2'-amino-5'-hydroxypropiophenone

Conditions
ConditionsYield
Stage #1: ethyl bromide With magnesium In tetrahydrofuran for 0.833333h; Inert atmosphere; Reflux;
Stage #2: 2-amino-5-methoxybenzonitrile In tetrahydrofuran at 5 - 20℃; Further stages;
3.5 g
1-(5-fluoro-2-nitrophenyl)propan-1-one
924648-17-9

1-(5-fluoro-2-nitrophenyl)propan-1-one

2'-amino-5'-hydroxypropiophenone
35364-15-9

2'-amino-5'-hydroxypropiophenone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: sodium hydroxide / 2 h / 0 - 20 °C
2: lithium chloride / N,N-dimethyl-formamide / 6 h / Reflux
3: sodium carbonate; sodium dithionite; water / 1 h / 20 °C
View Scheme
1-(5-methoxy-2-nitrophenyl)propan-1-one

1-(5-methoxy-2-nitrophenyl)propan-1-one

2'-amino-5'-hydroxypropiophenone
35364-15-9

2'-amino-5'-hydroxypropiophenone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: lithium chloride / N,N-dimethyl-formamide / 6 h / Reflux
2: sodium carbonate; sodium dithionite; water / 1 h / 20 °C
View Scheme
3-Fluorobenzaldehyde
456-48-4

3-Fluorobenzaldehyde

2'-amino-5'-hydroxypropiophenone
35364-15-9

2'-amino-5'-hydroxypropiophenone

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1.1: hydroxylamine hydrochloride; sodium hydroxide; water / ethanol / 4 h / 5 °C
2.1: acetic anhydride / 2 h / 110 °C
3.1: magnesium / tetrahydrofuran / 0.5 h / 40 °C
3.2: 1 h / 40 °C
4.1: nitric acid / dichloromethane / 12 h / 10 - 20 °C
5.1: sodium hydroxide / 2 h / 0 - 20 °C
6.1: lithium chloride / N,N-dimethyl-formamide / 6 h / Reflux
7.1: sodium carbonate; sodium dithionite; water / 1 h / 20 °C
View Scheme
3-fluorobenzaldehyde oxime
458-02-6

3-fluorobenzaldehyde oxime

2'-amino-5'-hydroxypropiophenone
35364-15-9

2'-amino-5'-hydroxypropiophenone

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: acetic anhydride / 2 h / 110 °C
2.1: magnesium / tetrahydrofuran / 0.5 h / 40 °C
2.2: 1 h / 40 °C
3.1: nitric acid / dichloromethane / 12 h / 10 - 20 °C
4.1: sodium hydroxide / 2 h / 0 - 20 °C
5.1: lithium chloride / N,N-dimethyl-formamide / 6 h / Reflux
6.1: sodium carbonate; sodium dithionite; water / 1 h / 20 °C
View Scheme
m-Fluorobenzonitrile
403-54-3

m-Fluorobenzonitrile

2'-amino-5'-hydroxypropiophenone
35364-15-9

2'-amino-5'-hydroxypropiophenone

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: magnesium / tetrahydrofuran / 0.5 h / 40 °C
1.2: 1 h / 40 °C
2.1: nitric acid / dichloromethane / 12 h / 10 - 20 °C
3.1: sodium hydroxide / 2 h / 0 - 20 °C
4.1: lithium chloride / N,N-dimethyl-formamide / 6 h / Reflux
5.1: sodium carbonate; sodium dithionite; water / 1 h / 20 °C
View Scheme
1-(3-fluorophenyl)propan-1-one
455-67-4

1-(3-fluorophenyl)propan-1-one

2'-amino-5'-hydroxypropiophenone
35364-15-9

2'-amino-5'-hydroxypropiophenone

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: nitric acid / dichloromethane / 12 h / 10 - 20 °C
2: sodium hydroxide / 2 h / 0 - 20 °C
3: lithium chloride / N,N-dimethyl-formamide / 6 h / Reflux
4: sodium carbonate; sodium dithionite; water / 1 h / 20 °C
View Scheme
C16H22O4

C16H22O4

2'-amino-5'-hydroxypropiophenone
35364-15-9

2'-amino-5'-hydroxypropiophenone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: sodium sulfate; potassium nitrate; sulfuric acid / dichloromethane / 5 - 30 °C / Inert atmosphere
2.1: potassium carbonate / methanol / 1 h / 25 - 30 °C
2.2: pH 1.5
3.1: sodium dithionite; sodium carbonate / methanol / 1 h / 0 - 30 °C
View Scheme
C12H11Cl3O4

C12H11Cl3O4

2'-amino-5'-hydroxypropiophenone
35364-15-9

2'-amino-5'-hydroxypropiophenone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: sodium sulfate; potassium nitrate; sulfuric acid / dichloromethane / -1 - 30 °C
2.1: potassium carbonate / methanol / 1 h / 25 - 30 °C
2.2: 1 h / 5 - 30 °C
View Scheme
Multi-step reaction with 3 steps
1.1: sodium sulfate; potassium nitrate; sulfuric acid / dichloromethane / -1 - 30 °C
2.1: potassium carbonate / methanol / 1 h / 25 - 30 °C
2.2: pH 3.5
3.1: sodium dithionite; sodium carbonate / methanol / 1 h / 0 - 30 °C
View Scheme
C12H10Cl3NO6

C12H10Cl3NO6

2'-amino-5'-hydroxypropiophenone
35364-15-9

2'-amino-5'-hydroxypropiophenone

Conditions
ConditionsYield
Stage #1: C12H10Cl3NO6 With potassium carbonate In methanol at 25 - 30℃; for 1h;
Stage #2: With sodium dithionite; sodium carbonate In methanol; water at 5 - 30℃; for 1h;
57.6 g
Multi-step reaction with 2 steps
1.1: potassium carbonate / methanol / 1 h / 25 - 30 °C
1.2: pH 3.5
2.1: sodium dithionite; sodium carbonate / methanol / 1 h / 0 - 30 °C
View Scheme
1-(3-hydroxyphenyl)propan-1-one
13103-80-5

1-(3-hydroxyphenyl)propan-1-one

2'-amino-5'-hydroxypropiophenone
35364-15-9

2'-amino-5'-hydroxypropiophenone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: nitric acid; acetic acid / water; ethyl acetate
2: sodium dithionite; sodium carbonate / methanol / 1 h / 0 - 30 °C
View Scheme
Multi-step reaction with 3 steps
1.1: sodium hydroxide / water / 0.17 h / 0 - 30 °C
1.2: 2 h / 0 - 10 °C
2.1: sodium sulfate; potassium nitrate; sulfuric acid / dichloromethane / -1 - 30 °C
3.1: potassium carbonate / methanol / 1 h / 25 - 30 °C
3.2: 1 h / 5 - 30 °C
View Scheme
Multi-step reaction with 4 steps
1.1: sodium hydroxide / water / 0.17 h / 0 - 30 °C
1.2: 2 h / 0 - 10 °C
2.1: sodium sulfate; potassium nitrate; sulfuric acid / dichloromethane / -1 - 30 °C
3.1: potassium carbonate / methanol / 1 h / 25 - 30 °C
3.2: pH 3.5
4.1: sodium dithionite; sodium carbonate / methanol / 1 h / 0 - 30 °C
View Scheme
Multi-step reaction with 4 steps
1.1: sodium hydroxide / water; dichloromethane / 0.17 h / 0 - 10 °C
1.2: 0 - 10 °C
2.1: sodium sulfate; potassium nitrate; sulfuric acid / dichloromethane / 5 - 30 °C / Inert atmosphere
3.1: potassium carbonate / methanol / 1 h / 25 - 30 °C
3.2: pH 1.5
4.1: sodium dithionite; sodium carbonate / methanol / 1 h / 0 - 30 °C
View Scheme
Multi-step reaction with 4 steps
1.1: sodium hydroxide / water; dichloromethane / 0.17 h / 0 - 10 °C
1.2: 10 °C
2.1: sodium sulfate; potassium nitrate; sulfuric acid / dichloromethane / 0 - 30 °C / Inert atmosphere
3.1: potassium carbonate / methanol / 1 h / 25 - 30 °C
3.2: pH 1.2
4.1: sodium dithionite; sodium carbonate / methanol / 1 h / 0 - 30 °C
View Scheme
C16H21NO6

C16H21NO6

2'-amino-5'-hydroxypropiophenone
35364-15-9

2'-amino-5'-hydroxypropiophenone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: potassium carbonate / methanol / 1 h / 25 - 30 °C
1.2: pH 1.5
2.1: sodium dithionite; sodium carbonate / methanol / 1 h / 0 - 30 °C
View Scheme
C12H14O4

C12H14O4

2'-amino-5'-hydroxypropiophenone
35364-15-9

2'-amino-5'-hydroxypropiophenone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: sodium sulfate; potassium nitrate; sulfuric acid / dichloromethane / 0 - 30 °C / Inert atmosphere
2.1: potassium carbonate / methanol / 1 h / 25 - 30 °C
2.2: pH 1.2
3.1: sodium dithionite; sodium carbonate / methanol / 1 h / 0 - 30 °C
View Scheme
2'-amino-5'-hydroxypropiophenone
35364-15-9

2'-amino-5'-hydroxypropiophenone

(4S)-4-ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione
110351-94-5

(4S)-4-ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione

7-ethyl-10-hydroxycamptothecin
86639-52-3, 110714-48-2, 130144-34-2

7-ethyl-10-hydroxycamptothecin

Conditions
ConditionsYield
With trifluoroacetic acid In toluene at 80℃; for 6h;92%
With toluene-4-sulfonic acid; acetic acid In toluene at 103℃; for 5.25 - 5.33h; Product distribution / selectivity;90.5%
Stage #1: 2'-amino-5'-hydroxypropiophenone; (4S)-4-ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione With toluene-4-sulfonic acid In acetic acid; toluene at 20℃;
Stage #2: at 100℃; for 18h;
89%
2'-amino-5'-hydroxypropiophenone
35364-15-9

2'-amino-5'-hydroxypropiophenone

4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione
102978-40-5

4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione

7-ethyl-10-hydroxycamptothecin
86639-52-3, 110714-48-2, 130144-34-2

7-ethyl-10-hydroxycamptothecin

Conditions
ConditionsYield
With iodine In N,N-dimethyl-formamide at 80℃; for 8h; Friedlaender synthesis; Inert atmosphere;75%
2'-amino-5'-hydroxypropiophenone
35364-15-9

2'-amino-5'-hydroxypropiophenone

2-tert-butoxycarbonyloxyimino-2-phenylacetonitrile

2-tert-butoxycarbonyloxyimino-2-phenylacetonitrile

2'-amino-5'-tert-butoxycarbonyloxypropiophenone
141975-09-9

2'-amino-5'-tert-butoxycarbonyloxypropiophenone

Conditions
ConditionsYield
With triethylamine In 1,4-dioxane; water for 24h; Ambient temperature;55.9%
2'-amino-5'-hydroxypropiophenone
35364-15-9

2'-amino-5'-hydroxypropiophenone

acetic anhydride
108-24-7

acetic anhydride

2-acetamido-5-hydroxy-propiophenone

2-acetamido-5-hydroxy-propiophenone

Conditions
ConditionsYield
at 130℃; for 2 - 3h;
2'-amino-5'-hydroxypropiophenone
35364-15-9

2'-amino-5'-hydroxypropiophenone

propionic acid anhydride
123-62-6

propionic acid anhydride

2-propionamido-5-hydroxy-propiophenone

2-propionamido-5-hydroxy-propiophenone

Conditions
ConditionsYield
at 130℃; for 2 - 3h;
2'-amino-5'-hydroxypropiophenone
35364-15-9

2'-amino-5'-hydroxypropiophenone

Chloroacetic anhydride
541-88-8

Chloroacetic anhydride

2-chloroacetamido-5-hydroxy-propiophenone

2-chloroacetamido-5-hydroxy-propiophenone

Conditions
ConditionsYield
at 130℃; for 2 - 3h;
2'-amino-5'-hydroxypropiophenone
35364-15-9

2'-amino-5'-hydroxypropiophenone

20-deethylallyl-7-ethyl-10-hydroxycamptothecin
141975-10-2

20-deethylallyl-7-ethyl-10-hydroxycamptothecin

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 55.9 percent / Et3N / dioxane; H2O / 24 h / Ambient temperature
2: 1.) AcOH, 2.) p-TsOH*H2O / 1.) 60 deg C, 0.5 h, 2.) 60 deg C, 15 h
View Scheme
1-chloroformyl-4-piperidinylpiperidine monohydrochloride

1-chloroformyl-4-piperidinylpiperidine monohydrochloride

2'-amino-5'-hydroxypropiophenone
35364-15-9

2'-amino-5'-hydroxypropiophenone

4-amino-3-propionylphenyl-1,4'-bipiperidine-1'-carboxylate

4-amino-3-propionylphenyl-1,4'-bipiperidine-1'-carboxylate

Conditions
ConditionsYield
With pyridine at 20℃; for 13h;
With pyridine at 20℃; for 13h;
6,6-(ethylenedioxy)-4-(2-fluoroethyl)-1,4,7,8-tetrahydro-4-hydroxypyrano[3,4-f]indolizine-3,10 (6H)-dione
142606-95-9

6,6-(ethylenedioxy)-4-(2-fluoroethyl)-1,4,7,8-tetrahydro-4-hydroxypyrano[3,4-f]indolizine-3,10 (6H)-dione

chloroform methanol
7285-11-2

chloroform methanol

2'-amino-5'-hydroxypropiophenone
35364-15-9

2'-amino-5'-hydroxypropiophenone

11-ethyl-4-(2-fluoroethyl)-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione

11-ethyl-4-(2-fluoroethyl)-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione

Conditions
ConditionsYield
With acetic acid In aqueous 80%-trifluoroacetic acid; dichloromethane
2'-amino-5'-hydroxypropiophenone
35364-15-9

2'-amino-5'-hydroxypropiophenone

irinotecan hydrochloirde
100286-90-6

irinotecan hydrochloirde

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: trifluoroacetic acid / toluene / 20 h / 85 - 90 °C / Industry scale
2: 1-Methylpyrrolidine / dichloromethane / 20 - 45 °C
3: hydrogenchloride / water / 3 h / 70 °C
View Scheme
Multi-step reaction with 3 steps
1: trifluoroacetic acid / toluene / 6 h / 80 °C
2: triethylamine; pyridine / 2 h / 20 °C / Inert atmosphere
3: hydrogenchloride; water / 3 h / 20 - 70 °C
View Scheme
Multi-step reaction with 4 steps
1.1: toluene-4-sulfonic acid / toluene / 5 h / Reflux
2.1: lithium hydroxide / methanol; water / 1 h / 25 - 30 °C
2.2: 18 - 22 °C
3.1: sulfuric acid / 2 h / 0 - 5 °C
4.1: triethylamine; pyridine / dichloromethane / 20 - 40 °C
4.2: pH 2-3
View Scheme
2'-amino-5'-hydroxypropiophenone
35364-15-9

2'-amino-5'-hydroxypropiophenone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: trifluoroacetic acid / toluene / 20 h / 85 - 90 °C / Industry scale
2: 1-Methylpyrrolidine / dichloromethane / 20 - 45 °C
View Scheme
Multi-step reaction with 2 steps
1: trifluoroacetic acid / toluene / 6 h / 80 °C
2: triethylamine; pyridine / 2 h / 20 °C / Inert atmosphere
View Scheme
2'-amino-5'-hydroxypropiophenone
35364-15-9

2'-amino-5'-hydroxypropiophenone

4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione
102978-40-5

4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione

4,11-diethyl-4,9-dihydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14 (4H,12H)-dione
130144-34-2

4,11-diethyl-4,9-dihydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14 (4H,12H)-dione

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene for 5h; Time; Reflux;422 g
2'-amino-5'-hydroxypropiophenone
35364-15-9

2'-amino-5'-hydroxypropiophenone

7-ethyl-10-hydroxycamptothecin
86639-52-3, 110714-48-2, 130144-34-2

7-ethyl-10-hydroxycamptothecin

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: toluene-4-sulfonic acid / toluene / 5 h / Reflux
2.1: lithium hydroxide / methanol; water / 1 h / 25 - 30 °C
2.2: 18 - 22 °C
3.1: sulfuric acid / 2 h / 0 - 5 °C
View Scheme
2'-amino-5'-hydroxypropiophenone
35364-15-9

2'-amino-5'-hydroxypropiophenone

C22H22N2O6*C9H13NO

C22H22N2O6*C9H13NO

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: toluene-4-sulfonic acid / toluene / 5 h / Reflux
2.1: lithium hydroxide / methanol; water / 1 h / 25 - 30 °C
2.2: 18 - 22 °C
View Scheme

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