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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis according to the contract research and development services for the fine c

1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine

Cas:4004-05-1

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so

1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine 4004-05-1

Cas:4004-05-1

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 4004-05-1 with competitive price

Cas:4004-05-1

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

Qingdao Beluga Import and Export Co., LTD

1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine CAS:4004-05-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in h

1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine CAS:4004-05-1

Cas:4004-05-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

9-Octadecenoic acid(9Z)-,1,1'-[(1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl]ester

Cas:4004-05-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine

Cas:4004-05-1

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

1)quick response within 12 hours; 2)quality guarantee: all products are strictly tested by our qc, confirmed by qa and approved by third party lab in china, usa, canada, germany, uk, italy, france etc. 3) oem/odm available; 4) rea

1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINECAS NO.: 4004-05-1

Cas:4004-05-1

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE

Cas:4004-05-1

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE

Cas:4004-05-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE

Cas:4004-05-1

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Hangzhou ZeErRui Chemical Co., Ltd.

Product Name: dope 1,2-dioleoyl-sn-glycerin-3-phosphoryl ethanolamine (dope) Englishalias:DOPE;Dioleoylphosphoethanolamine;L-A-phosphatidylethanolamine dioleoyl;1,2-dioleoyl-sn-glycero-3-phosphatidylethanolamine; 1,2-dioleoyl-sn-glycerol-3-phos

dope 1,2-dioleoyl-sn-glycerin-3-phosphoryl ethanolamine (dope)

Cas:4004-05-1

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE

Cas:4004-05-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Shanghai Scochem Technology Co., Ltd.

Shanghai Sikuo Chemical Technology Co., Ltd. was established in 2012 and is a chemical supplier that integrates research and development, production, and sales. Dedicated to providing basic chemical, fine chemical, pesticide, and pharmaceutical inter

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

Cas:4004-05-1

Min.Order:25 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE

Cas:4004-05-1

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:NA Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application:It is an important raw materi

1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE

Cas:4004-05-1

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine

Cas:4004-05-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stock Package:1kg Application:pharmaceutical intermediates

Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec L-alpha-Phosphatidylethanolamine, Dioleoyl 1g

Cas:4004-05-1

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages? High purity, all above 98.5%, no impurities after dissolution? We will test each batch to ensure quality? OEM and private brand services designed for free? Various cap colors available? We can also provide MT1 peptide powder2.

1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE

Cas:4004-05-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

HANGZHOU TIANYE CHEMICALS CO., LTD.

We product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Application:Chemical intermediate

(Z)-(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dioleate

Cas:4004-05-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hubei Langyou International Trading Co., Ltd

1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE Application:1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE

1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE

Cas:4004-05-1

Min.Order:0

Negotiable

Type:Other

inquiry

Hangzhou Fandachem Co.,Ltd

1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine cas 4004-05-1Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine cas 4004-05-1

Cas:4004-05-1

Min.Order:0

Negotiable

Type:Other

inquiry

Hunan Longxianng Runhui Trading Co.,Ltd

1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINEAppearance:NA Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application:It is an important raw material and medic

1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE

Cas:4004-05-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Yuanye Bio-Technology Co., Ltd.

good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:100mg Application:Pharma;Industry;Agricultural;chemical reaserch Transportation:by express or by sea Port:Any po

L-alpha-Phosphatidylethanolamine, Dioleoyl

Cas:4004-05-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hunan Russell Chemicals Technology Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China

1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE 4004-05-1

Cas:4004-05-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Chemsigma International Co.,Ltd.

bulk?production Application:Pharmaceutical intermediates

1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE

Cas:4004-05-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE

Cas:4004-05-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

NUTROCHEM- MANUFACTURE PLACE

best seller Application:API

1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE

Cas:4004-05-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

dioleoylphosphatidylcholine
4235-95-4

dioleoylphosphatidylcholine

ethanolamine
141-43-5

ethanolamine

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
4004-05-1

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

Conditions
ConditionsYield
With PLD transesterification;90%
L-1,2-Di-O-oleoyl-glycerin-3-phosphorsaeurebenzylester-<2-triphenylmethylamino-ethylester>

L-1,2-Di-O-oleoyl-glycerin-3-phosphorsaeurebenzylester-<2-triphenylmethylamino-ethylester>

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
4004-05-1

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

Conditions
ConditionsYield
(i) NaI, (ii) aq. AcOH; Multistep reaction;
1,2-dioleoyl-sn-glycerol
24529-88-2

1,2-dioleoyl-sn-glycerol

ethanolamine
141-43-5

ethanolamine

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
4004-05-1

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

Conditions
ConditionsYield
With triethylamine; trichlorophosphate 1) THF, a) 0 deg C, 1 h, b) room temp., 3 h, 2) THF, a) 0 deg C, 4 h, b) room temp., 8 h; Yield given. Multistep reaction;
sodium-salt of phosphoric acid-<(R)-1,2-bis-oleoyloxy-propyl ester>-<2-phthalimido-ethyl ester>

sodium-salt of phosphoric acid-<(R)-1,2-bis-oleoyloxy-propyl ester>-<2-phthalimido-ethyl ester>

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
4004-05-1

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

Conditions
ConditionsYield
With hydrazine hydrate
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
4004-05-1

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 66 percent
2: 80 percent
3: 90 percent / PLD
View Scheme
1,2-dioleoyl-sn-glycero-3-phosphate sodium salt
108392-02-5

1,2-dioleoyl-sn-glycero-3-phosphate sodium salt

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
4004-05-1

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 80 percent
2: 90 percent / PLD
View Scheme
(S)-3-(3,4-Dimethoxybenzyloxy)propane-1,2-diyl Dioleate
139115-88-1

(S)-3-(3,4-Dimethoxybenzyloxy)propane-1,2-diyl Dioleate

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
4004-05-1

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 84 percent / 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) / CH2Cl2; H2O / 2 h
2: 1) Et3N, POCl3, 2) Et3N / 1) THF, a) 0 deg C, 1 h, b) room temp., 3 h, 2) THF, a) 0 deg C, 4 h, b) room temp., 8 h
View Scheme
L-1,2-Di-O-oleoyl-glycerin-3-phosphorsaeure-dibenzylester
19805-13-1

L-1,2-Di-O-oleoyl-glycerin-3-phosphorsaeure-dibenzylester

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
4004-05-1

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: (i) NaI, (ii) AgNO3
2: benzene
3: (i) NaI, (ii) aq. AcOH
View Scheme
L-1,2-Di-O-oleoyl-glycerin-3-phosphorsaeurebenzylester-silbersalz

L-1,2-Di-O-oleoyl-glycerin-3-phosphorsaeurebenzylester-silbersalz

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
4004-05-1

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: benzene
2: (i) NaI, (ii) aq. AcOH
View Scheme
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
4004-05-1

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

3-propionic acid
80028-35-9

3-propionic acid

C50H88N3O9P

C50H88N3O9P

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In dichloromethane; N,N-dimethyl-formamide at 20℃; Inert atmosphere;100%
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
4004-05-1

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

N2-[N2,N6-bis(tert-butoxycarbonyl)-L-lysyl]-N6-(tert-butoxycarbonyl)-L-lysine
45315-76-2

N2-[N2,N6-bis(tert-butoxycarbonyl)-L-lysyl]-N6-(tert-butoxycarbonyl)-L-lysine

C68H126N5O16P

C68H126N5O16P

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In dichloromethane; N,N-dimethyl-formamide at 20℃; Inert atmosphere;97%
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
4004-05-1

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

N-hydroxysuccinimidyl ester 3-methyl-3-(2,4,5-trimethyl-3,6-dioxocyclo-hexa-1,4-dienyl) butanoic acid
121030-88-4

N-hydroxysuccinimidyl ester 3-methyl-3-(2,4,5-trimethyl-3,6-dioxocyclo-hexa-1,4-dienyl) butanoic acid

C55H94NO11P
1073588-75-6

C55H94NO11P

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0℃; Inert atmosphere;96%
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
4004-05-1

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

Propiolic acid
471-25-0

Propiolic acid

1,2-dioleoyl-sn-glycero-3-phosphoethanoloamine-N-prop-2'-ynamide
910227-37-1

1,2-dioleoyl-sn-glycero-3-phosphoethanoloamine-N-prop-2'-ynamide

Conditions
ConditionsYield
With N-(3-dimethylaminopropyl)-N-ethylcarbodiimide In dichloromethane at 20℃; for 40h;95%
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
4004-05-1

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

hexanedioic acid bis(N-hydroxysuccinimide ester)
59156-70-6

hexanedioic acid bis(N-hydroxysuccinimide ester)

DOPE-Ad-ONSu
930280-91-4

DOPE-Ad-ONSu

Conditions
ConditionsYield
With triethylamine In chloroform; N,N-dimethyl-formamide at 20℃; for 2h;95%
In chloroform; N,N-dimethyl-formamide
In chloroform; N,N-dimethyl-formamide
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
4004-05-1

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

3-(1-(1-(4-((6-amino-8-hydroxy-2-(2-methoxyethoxy)-9H-purin-9-yl)methyl)phenyl)-1-oxo-5,8,11,14,17,20,23,26,29,32-decaoxa-2-azatetratriacontan-34-yl)-1H-1,2,3-triazol-4-yl)propanoic acid
1149339-80-9

3-(1-(1-(4-((6-amino-8-hydroxy-2-(2-methoxyethoxy)-9H-purin-9-yl)methyl)phenyl)-1-oxo-5,8,11,14,17,20,23,26,29,32-decaoxa-2-azatetratriacontan-34-yl)-1H-1,2,3-triazol-4-yl)propanoic acid

2-(3-(1-(1-(4-((6-amino-8-hydroxy-2-(2-methoxyethoxy)-9H-purin-9-yl)methyl)phenyl)-1-oxo-5,8,11,14,17,20,23,26,29,32-decaoxa-2-azatetratriacontan-34-yl)-1H-1,2,3-triazole-4-yl)propanamido)ethyl 2,3-bis(oleoyloxy)propyl phosphate

2-(3-(1-(1-(4-((6-amino-8-hydroxy-2-(2-methoxyethoxy)-9H-purin-9-yl)methyl)phenyl)-1-oxo-5,8,11,14,17,20,23,26,29,32-decaoxa-2-azatetratriacontan-34-yl)-1H-1,2,3-triazole-4-yl)propanamido)ethyl 2,3-bis(oleoyloxy)propyl phosphate

Conditions
ConditionsYield
With 2-(1H-9-azabenzotriazol-1-yl)-1,1,3,3-tetramethyluroniumhexafluorophosphate; triethylamine In dichloromethane; N,N-dimethyl-formamide at 20℃;92%
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
4004-05-1

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

3-(2'-acetoxy-4',6'-dimethylphenyl)-3,3-dimethylpropanoic acid
134098-68-3

3-(2'-acetoxy-4',6'-dimethylphenyl)-3,3-dimethylpropanoic acid

C56H96NO11P

C56H96NO11P

Conditions
ConditionsYield
Stage #1: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine; 3-(2'-acetoxy-4',6'-dimethylphenyl)-3,3-dimethylpropanoic acid With benzotriazol-1-ol In N,N-dimethyl-formamide at 0℃; for 0.0833333h; Inert atmosphere;
Stage #2: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 5h; Inert atmosphere;
92%
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
4004-05-1

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

4-{[6-amino-2-(2-methoxyethoxy)-8-oxo-7H-purine-9(8H)-yl]methyl}benzoic acid
1062444-54-5

4-{[6-amino-2-(2-methoxyethoxy)-8-oxo-7H-purine-9(8H)-yl]methyl}benzoic acid

(2R)‑3‑(((2‑(4‑((6‑amino‑2‑(2‑methoxyethoxy)‑8‑oxo‑7,8‑dihydro‑9H-purin‑9‑yl)methyl)benzamido)ethoxy)(hydroxy)phosphoryl)oxy)propane‑1,2‑diyldioleate

(2R)‑3‑(((2‑(4‑((6‑amino‑2‑(2‑methoxyethoxy)‑8‑oxo‑7,8‑dihydro‑9H-purin‑9‑yl)methyl)benzamido)ethoxy)(hydroxy)phosphoryl)oxy)propane‑1,2‑diyldioleate

Conditions
ConditionsYield
With triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In dichloromethane; N,N-dimethyl-formamide79%
Stage #1: 4-{[6-amino-2-(2-methoxyethoxy)-8-oxo-7H-purine-9(8H)-yl]methyl}benzoic acid With triethylamine; HATU In N,N-dimethyl-formamide at 20℃; for 0.25h; Inert atmosphere;
Stage #2: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine In dichloromethane; N,N-dimethyl-formamide for 12h; Solvent; Reagent/catalyst;
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
4004-05-1

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

fluoresceinyl 5-isothiocyanate
1173-43-9

fluoresceinyl 5-isothiocyanate

C62H89N2O13PS

C62H89N2O13PS

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; Inert atmosphere;79%
3-(2-((bis(benzyloxy)phosphoryl)oxy)-4,6-dimethylphenyl)-3-methylbutanoic acid
153910-64-6

3-(2-((bis(benzyloxy)phosphoryl)oxy)-4,6-dimethylphenyl)-3-methylbutanoic acid

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
4004-05-1

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

(2R)-3-(((2-(3-(2-((bis(benzyloxy)phosphoryl)oxy)-4,6-dimethylphenyl)-3-methylbutanamido)ethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dioleate

(2R)-3-(((2-(3-(2-((bis(benzyloxy)phosphoryl)oxy)-4,6-dimethylphenyl)-3-methylbutanamido)ethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dioleate

Conditions
ConditionsYield
Stage #1: 3-(2-((bis(benzyloxy)phosphoryl)oxy)-4,6-dimethylphenyl)-3-methylbutanoic acid; 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine With benzotriazol-1-ol In N,N-dimethyl-formamide at 0℃; for 0.0833333h;
Stage #2: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide
77%
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
4004-05-1

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

C16H17NO6
1073493-61-4

C16H17NO6

C53H90NO11P
1073588-74-5

C53H90NO11P

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0℃; Inert atmosphere;75%
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
4004-05-1

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

N-(tert-butoxycarbonyl)-4-aminobutanoic acid
57294-38-9

N-(tert-butoxycarbonyl)-4-aminobutanoic acid

C50H93N2O11P

C50H93N2O11P

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine; HATU In chloroform; N,N-dimethyl-formamide at 20℃; Inert atmosphere;64%
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
4004-05-1

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

5-(((2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-yl)oxy)-5-oxopentanoic acid
1415981-75-7

5-(((2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-yl)oxy)-5-oxopentanoic acid

(Z)-(2R)-3-(((2-(5-(((2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-yl)oxy)-5-oxopentanamido)ethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dioleate
1415981-76-8

(Z)-(2R)-3-(((2-(5-(((2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-yl)oxy)-5-oxopentanamido)ethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dioleate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine; HATU In chloroform; N,N-dimethyl-formamide at 20℃; Inert atmosphere;61%
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
4004-05-1

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

(1R,8S,9ξ)-bicyclo[6.1.0]non-4-yn-9-ylmethyl (4-nitrophenyl) carbonate

(1R,8S,9ξ)-bicyclo[6.1.0]non-4-yn-9-ylmethyl (4-nitrophenyl) carbonate

(2R)-3-(((2-(((((1R,8S,9s)-bicyclo[6.1.0]non-4-yn-9-yl)methoxy)carbonyl)amino)ethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dioleate

(2R)-3-(((2-(((((1R,8S,9s)-bicyclo[6.1.0]non-4-yn-9-yl)methoxy)carbonyl)amino)ethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dioleate

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran; N,N-dimethyl-formamide at 60℃; for 6h;60%
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
4004-05-1

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

4-{[6-amino-2-(2-methoxyethoxy)-8-oxo-7H-purine-9(8H)-yl]methyl}benzoic acid
1062444-54-5

4-{[6-amino-2-(2-methoxyethoxy)-8-oxo-7H-purine-9(8H)-yl]methyl}benzoic acid

2-(4-((6-amino-2-(2-methoxyethoxy)-8-oxo-7H-purin-9(8H)-yl)methyl)benzamido)ethyl 2,3-bis(oleoyloxy)propyl phosphate
1346265-99-3

2-(4-((6-amino-2-(2-methoxyethoxy)-8-oxo-7H-purin-9(8H)-yl)methyl)benzamido)ethyl 2,3-bis(oleoyloxy)propyl phosphate

Conditions
ConditionsYield
With 2-(1H-9-azabenzotriazol-1-yl)-1,1,3,3-tetramethyluroniumhexafluorophosphate; triethylamine In dichloromethane; N,N-dimethyl-formamide at 20℃;58%
2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetic acid

2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetic acid

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
4004-05-1

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

(2R)-3-((hydroxy(2-(2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamido)ethoxy)phosphoryl)oxy)propane-1,2-diyl dioleate

(2R)-3-((hydroxy(2-(2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamido)ethoxy)phosphoryl)oxy)propane-1,2-diyl dioleate

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In chloroform; N,N-dimethyl-formamide at 0 - 20℃; for 6h; Inert atmosphere;55%
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
4004-05-1

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

4-methoxybenzoic acid
100-09-4

4-methoxybenzoic acid

DOPE-Anisamide

DOPE-Anisamide

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 24h; Inert atmosphere; Darkness;51%
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
4004-05-1

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

PEG7 Bis-PFP ster

PEG7 Bis-PFP ster

DOPE-PEG7-PFP

DOPE-PEG7-PFP

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran at 20℃;50%
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
4004-05-1

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

C19H16N2O6

C19H16N2O6

3-(((2-(2-(3-benzoyl-6,7-dimethoxy-2-oxoquinoxalin-1(2H)-yl)acetamido)ethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dioleate

3-(((2-(2-(3-benzoyl-6,7-dimethoxy-2-oxoquinoxalin-1(2H)-yl)acetamido)ethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dioleate

Conditions
ConditionsYield
Stage #1: C19H16N2O6 With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane; N,N-dimethyl-formamide for 0.25h;
Stage #2: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine In dichloromethane; N,N-dimethyl-formamide at 20℃;
39%
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
4004-05-1

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

PEG-17 bis-NHS-ester

PEG-17 bis-NHS-ester

DOPE-PEG17-NHS

DOPE-PEG17-NHS

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran at 20℃; Inert atmosphere;36%
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
4004-05-1

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

all-trans-retinoic-acid
302-79-4

all-trans-retinoic-acid

(Z)-(2R)-3-(((2-((2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenamido)ethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dioleate
1415981-98-4

(Z)-(2R)-3-(((2-((2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenamido)ethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dioleate

Conditions
ConditionsYield
Stage #1: all-trans-retinoic-acid With diethylamino-sulfur trifluoride In diethyl ether at -78 - 20℃;
Stage #2: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine With sodium carbonate In chloroform at 20℃; for 24h;
28%
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
4004-05-1

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

C15H21F2NO4

C15H21F2NO4

C56H97F2N2O11P

C56H97F2N2O11P

Conditions
ConditionsYield
Stage #1: C15H21F2NO4 With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide for 0.5h; Inert atmosphere; Cooling with ice;
Stage #2: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine In tetrahydrofuran; N,N-dimethyl-formamide at 20℃; for 48h; Inert atmosphere; Cooling with ice;
20.8%
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
4004-05-1

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

1,2-distearoyl-sn-glycero-3-phosphoethanolamine
1069-79-0

1,2-distearoyl-sn-glycero-3-phosphoethanolamine

Conditions
ConditionsYield
With acetic acid; platinum Hydrogenation;
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
4004-05-1

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

estra-1,3,5(10)-triene-3,17β-diol 17β-hemisuccinate
7698-93-3, 65684-87-9, 93939-81-2

estra-1,3,5(10)-triene-3,17β-diol 17β-hemisuccinate

(Z)-Octadec-9-enoic acid (R)-2-(hydroxy-{2-[3-((13S,17S)-3-hydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-17-yloxycarbonyl)-propionylamino]-ethoxy}-phosphoryloxy)-1-((Z)-octadec-9-enoyloxymethyl)-ethyl ester
139116-09-9

(Z)-Octadec-9-enoic acid (R)-2-(hydroxy-{2-[3-((13S,17S)-3-hydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-17-yloxycarbonyl)-propionylamino]-ethoxy}-phosphoryloxy)-1-((Z)-octadec-9-enoyloxymethyl)-ethyl ester

Conditions
ConditionsYield
With benzotriazol-1-ol; dicyclohexyl-carbodiimide In dichloromethane; acetone for 5h;
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
4004-05-1

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

androst-4-en-3-one-17β-carboxylic acid
302-97-6

androst-4-en-3-one-17β-carboxylic acid

C61H104NO10P
139116-00-0

C61H104NO10P

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane for 6h; Ambient temperature;

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