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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

2-Chloro-5-hydroxypyridine

Cas:41288-96-4

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 2-Chloro-5-Hydroxypyridine supplier in China

Cas:41288-96-4

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Wuhan Fortuna Chemical Co.,Ltd

High quality 2-Chloro-5-hydroxypyridine CAS 41288-96-4 with factory price Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/

High quality 2-Chloro-5-hydroxypyridine CAS 41288-96-4 with factory price

Cas:41288-96-4

Min.Order:10 Kilogram

FOB Price: $10.0

Type:Trading Company

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

2-Chloro-5-hydroxypyridine

Cas:41288-96-4

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 2-Chloro-5-Hydroxypyridine

Cas:41288-96-4

Min.Order:1

Negotiable

Type:Other

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

2-Chloro-5-Hydroxypyridine

Cas:41288-96-4

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Chemwill Asia Co., Ltd.

2-Chloro-5-hydroxypyridine CAS 41288-96-4 In stock

Cas:41288-96-4

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Manufacturers

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Jinan Finer Chemical Co., Ltd

2-Chloro-5-hydroxypyridine

Cas:41288-96-4

Min.Order:1 Gram

FOB Price: $22.0

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 41288-96-4 with best quality

Cas:41288-96-4

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Name: 2-Chloro-5-Hydroxypyridine Molecular Formula:C5H4ClNO Molecular Weight:129.54 CAS No.:41288-96-4 Appearance:Similar White To Slight Yellow Crystal Appearance:Similar White To Slight Yellow Crystal Storage:Store in cool and dry place, away f

2-Chloro-5-Hydroxypyridine

Cas:41288-96-4

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2-Chloro-5-hydroxypyridine 41288-96-4

Cas:41288-96-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Shanghai Minstar Chemical Co., Ltd

Product Name: 2-Chloro-5-hydroxypyridine Synonyms: 6-CHLOROPYRIDIN-3-OL;6-Chloro-3-pyridinol;3-PYRIDINOL, 6-CHLORO-;2-CHLORO-5-HYDROXYPYRIDINE;2-CHLORO-5-PYRIDINOL;2-Chloro-5-Pyridol;2-Chloropyridin-5-ol;3-Pyridinol,6-chloro-(9CI) CAS: 41288

2-Chloro-5-hydroxypyridine

Cas:41288-96-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Organic Synthesis,2-Chloro-5-hydroxypyridine CAS:41288-96-4

Cas:41288-96-4

Min.Order:1 Kilogram

FOB Price: $32.0 / 36.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

2-Chloro-5-hydroxypyridine CAS:41288-96-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organ

2-Chloro-5-hydroxypyridine CAS:41288-96-4

Cas:41288-96-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2-Chloro-5-hydroxypyridine

Cas:41288-96-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:41288-96-4

Cas:41288-96-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

2-Chloro-5-Hydroxypyridine

Cas:41288-96-4

Min.Order:0

Negotiable

Type:Manufacturers

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Triumph International Development Limilted

Triumph has the complete production of G- KG - MT service chain,we can make the new technology into productivity quickly in the research and development of new products. Main Business Custom Synthesis: Trading(Raw Mater

2-Chloro-5-Hydroxypyridine

Cas:41288-96-4

Min.Order:0 Metric Ton

FOB Price: $18.0 / 20.0

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We have s

2-Chloro-5-hydroxypyridine

Cas:41288-96-4

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

2-Chloro-5-hydroxypyridine

Cas:41288-96-4

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

6-chloropyridin-3-ol

Cas:41288-96-4

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2-Chloro-5-hydroxypyridine

Cas:41288-96-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shaanxi Cuicheng Biomedical Technology Co., Ltd.

Why Choose Us: 1. Factory direct sales, so we can provide the competitive price and high quality product base on 8 years of production and R&D experience. 2. It is available in stock for quick shipment.Products could be packaged according to cu

2-Chloro-5-hydroxypyridine

Cas:41288-96-4

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 2-Chloro-5-Hydroxypyridine

Cas:41288-96-4

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:light yellow crystal Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:25kg/drum, or as per your request. Application:For medicine , pesticide in

2-Chloro-5-hydroxypyridine

Cas:41288-96-4

Min.Order:1 Gram

Negotiable

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

TIANFUCHEM 41288-96-4 2-Chloro-5-hydroxypyridine

Cas:41288-96-4

Min.Order:1 Kilogram

FOB Price: $1000.0

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: 2-Chloro-5-Hydroxypyridine CAS No.:41288-96-4 Molecule Formula:C5H4ClNO Molecule Weight:129.54 Purity: 98.0% Package: 25kg/drum Description:White or off-white powder Manufacture Standards:Enterprise Standard TESTING

High Quality 2-Chloro-5-Hydroxypyridine in stock

Cas:41288-96-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

2-Chloro-5-hydroxypyridine

Cas:41288-96-4

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

2-Chloro-5-hydroxypyridine

Cas:41288-96-4

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

2-Chloro-5-hydroxypyridine

Cas:41288-96-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

5-Acetoxy-2-chloropyridine
188057-24-1

5-Acetoxy-2-chloropyridine

6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

Conditions
ConditionsYield
With potassium carbonate In methanol at 20℃; for 2h;96%
With hydrogenchloride; potassium carbonate In methanol96%
With potassium carbonate In methanol at 20℃;94%
potassium (6-chloropyridin-3-yl)trifluoroborate
1235099-38-3

potassium (6-chloropyridin-3-yl)trifluoroborate

6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

Conditions
ConditionsYield
With Oxone; water In acetone at 20℃; for 0.0833333h;91%
6-chloropyridin-3-ylboronic acid
444120-91-6

6-chloropyridin-3-ylboronic acid

6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

Conditions
ConditionsYield
With dihydrogen peroxide In dichloromethane; water at 20℃; for 20h;82%
5-bromo-2-chloropyridine
53939-30-3

5-bromo-2-chloropyridine

6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

Conditions
ConditionsYield
With N1,N2-bis(thiophen-2-ylmethyl)oxalamide; caesium carbonate; copper(I) bromide; sodium hydroxide In water; dimethyl sulfoxide at 85℃; for 20h; Reagent/catalyst; Temperature; Glovebox; Schlenk technique; Sealed tube; Inert atmosphere; chemoselective reaction;56%
6-Chloro-pyridin-3-ylamine
5350-93-6

6-Chloro-pyridin-3-ylamine

6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

Conditions
ConditionsYield
Stage #1: 6-Chloro-pyridin-3-ylamine With sulfuric acid; sodium nitrite at 5 - 20℃; for 0.5h;
Stage #2: With acetic acid at 100℃;
54%
With sulfuric acid; sodium nitrite Yield given;
Multi-step reaction with 2 steps
1: 1.) t-BuONO, BF3*OEt2 / 1.) CH2Cl2, DME, 2.) heating
2: K2CO3 / methanol
View Scheme
Multi-step reaction with 2 steps
1: diethyl ether; ethanol; acetic anhydride
2: acetic acid / aqueous KOH
View Scheme
C11H12(2)HClOS

C11H12(2)HClOS

2-chloro-5-(4,4, 5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
444120-94-9

2-chloro-5-(4,4, 5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

A

6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

B

(4R,5R)-4,5-[2H]2-5-(2-chloropyrid-5-yl)octa-1,7-dien-4-ol

(4R,5R)-4,5-[2H]2-5-(2-chloropyrid-5-yl)octa-1,7-dien-4-ol

C

C9H9(2)HClN

C9H9(2)HClN

D

C9H9(2)HClNO

C9H9(2)HClNO

E

1-Methyl-4-((R)-2-methyl-propane-2-sulfinyl)-benzene
1693-83-0

1-Methyl-4-((R)-2-methyl-propane-2-sulfinyl)-benzene

Conditions
ConditionsYield
Stage #1: C11H12(2)HClOS; 2-chloro-5-(4,4, 5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine With phenyllithium In tetrahydrofuran at -78 - 20℃; for 3h; Inert atmosphere;
Stage #2: With sodium hydroxide In tetrahydrofuran; water at 0℃; for 1.5h;
A n/a
B 16%
C 28%
D n/a
E 7%
C7H9BClNO2

C7H9BClNO2

6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

Conditions
ConditionsYield
With dihydrogen peroxide In tetrahydrofuran; cyclohexane; acetic acid at 20℃; for 0.5h; Oxidation;
2-chloropyridine
109-09-1

2-chloropyridine

A

6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

B

2-chloro-3-hydroxypyridine
6636-78-8

2-chloro-3-hydroxypyridine

Conditions
ConditionsYield
With dihydrogen peroxide; copper(II) nitrate In phosphate buffer; acetonitrile at 50℃; for 5h;
2-chloro-5-(4,4, 5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
444120-94-9

2-chloro-5-(4,4, 5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

Conditions
ConditionsYield
With dihydrogen peroxide In dichloromethane; water at 20℃; for 20h;
6-Chloro-pyridin-3-ylamine
5350-93-6

6-Chloro-pyridin-3-ylamine

A

6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

B

(S)-BocNHCH(C2H5)CH2OH or (S)-BocNHCH(C2H5)CH2OTs

(S)-BocNHCH(C2H5)CH2OH or (S)-BocNHCH(C2H5)CH2OTs

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: BF3*Et2O; i-BuONO / 1,2-dimethoxy-ethane; CH2Cl2 / 0 °C
1.2: 62 percent / 75 °C
2.1: 94 percent / K2CO3 / methanol / 20 °C
View Scheme
2-choro-5-iodopyridine
69045-79-0

2-choro-5-iodopyridine

6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: BuLi / tetrahydrofuran; cyclohexane / 0.33 h / -78 °C
2: tetrahydrofuran; cyclohexane / 0.75 h / -10 °C
3: 30 percent H2O2 / tetrahydrofuran; cyclohexane; acetic acid / 0.5 h / 20 °C
View Scheme
5-lithio-2-chloropyridine
211377-86-5

5-lithio-2-chloropyridine

6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: tetrahydrofuran; cyclohexane / 0.75 h / -10 °C
2: 30 percent H2O2 / tetrahydrofuran; cyclohexane; acetic acid / 0.5 h / 20 °C
View Scheme
boron trifluoride-tetrahydrofuran complex
462-34-0

boron trifluoride-tetrahydrofuran complex

1-(azetidin-1-yl)-2-(6-chloropyridin-3-yloxy)-2-methylpropan-1-one

1-(azetidin-1-yl)-2-(6-chloropyridin-3-yloxy)-2-methylpropan-1-one

A

6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

B

C12H20BClN2O

C12H20BClN2O

Conditions
ConditionsYield
In tetrahydrofuran at 45℃;
ethyl 2-(6-chloropyridin-3-yloxy)-2-methylpropanoate
1360056-04-7

ethyl 2-(6-chloropyridin-3-yloxy)-2-methylpropanoate

A

6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

B

C12H20BClN2O

C12H20BClN2O

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: lithium hydroxide / tetrahydrofuran; water / 2.5 h / 20 °C
2: dichloromethane / 2.67 h / 14 - 18 °C
3: triethylamine / dichloromethane / 2 h / Inert atmosphere; Reflux
4: tetrahydrofuran / 45 °C
View Scheme
2-(6-chloropyridin-3-yloxy)-2-methylpropanoic acid

2-(6-chloropyridin-3-yloxy)-2-methylpropanoic acid

A

6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

B

C12H20BClN2O

C12H20BClN2O

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: dichloromethane / 2.67 h / 14 - 18 °C
2: triethylamine / dichloromethane / 2 h / Inert atmosphere; Reflux
3: tetrahydrofuran / 45 °C
View Scheme
(6-chloropyridin-3-yl)(mesityl)iodonium trifluoromethanesulfonate
1426083-18-2

(6-chloropyridin-3-yl)(mesityl)iodonium trifluoromethanesulfonate

6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

Conditions
ConditionsYield
With water; sodium acetate; copper(l) chloride In N,N-dimethyl-formamide at 40℃; for 2h; Inert atmosphere; Sealed tube;
6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

benzyl bromide
100-39-0

benzyl bromide

5-(benzyloxy)-2-chloropyridine
84611-43-8

5-(benzyloxy)-2-chloropyridine

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 60℃; for 18h;100%
With potassium carbonate In N,N-dimethyl-formamide at 40℃; for 25h;82%
With caesium carbonate In N,N-dimethyl-formamide79%
6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

3-(bromomethyl)-2,4-difluoro-1,5-dimethoxybenzene

3-(bromomethyl)-2,4-difluoro-1,5-dimethoxybenzene

2-chloro-5-((2,6-difluoro-3,5-dimethoxybenzyl)oxy)pyridine

2-chloro-5-((2,6-difluoro-3,5-dimethoxybenzyl)oxy)pyridine

Conditions
ConditionsYield
Stage #1: 6-chloropyridine-3-ol With potassium carbonate In N,N-dimethyl-formamide for 0.166667h;
Stage #2: 3-(bromomethyl)-2,4-difluoro-1,5-dimethoxybenzene In N,N-dimethyl-formamide at 80℃; for 4h;
100%
6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

6-chloro-2-iodopyridin-3-ol
188057-26-3

6-chloro-2-iodopyridin-3-ol

Conditions
ConditionsYield
With iodine; sodium hydrogencarbonate In water99%
With iodine; sodium carbonate In water95%
With iodine; sodium carbonate In water at 20℃; for 48h;95%
6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

bromethyl methyl ether
13057-17-5

bromethyl methyl ether

2-chloro-5-(methoxymethoxy)pyridine
877133-56-7

2-chloro-5-(methoxymethoxy)pyridine

Conditions
ConditionsYield
Stage #1: 6-chloropyridine-3-ol With sodium hydride In N,N-dimethyl-formamide at 5℃; for 1h; Inert atmosphere;
Stage #2: bromethyl methyl ether In N,N-dimethyl-formamide at 20℃;
99%
Stage #1: 6-chloropyridine-3-ol With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 0.166667h; Inert atmosphere;
Stage #2: bromethyl methyl ether In N,N-dimethyl-formamide; mineral oil at 20℃; for 2h;
87%
Stage #1: 6-chloropyridine-3-ol With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃; for 1h; Inert atmosphere;
Stage #2: bromethyl methyl ether In N,N-dimethyl-formamide at 10 - 20℃; for 2h; Inert atmosphere;
75%
Stage #1: 6-chloropyridine-3-ol With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 25℃; for 1h;
Stage #2: bromethyl methyl ether In N,N-dimethyl-formamide; mineral oil at 10 - 25℃; for 2h;
75%
Stage #1: 6-chloropyridine-3-ol With sodium hydride In N,N-dimethyl-formamide at 0 - 10℃; for 0.5h;
Stage #2: bromethyl methyl ether In N,N-dimethyl-formamide at 20℃;
179 g
6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

methyl iodide
74-88-4

methyl iodide

2-chloro-5-methoxypyridine
139585-48-1

2-chloro-5-methoxypyridine

Conditions
ConditionsYield
With sodium methylate In methanol; N,N-dimethyl-formamide at 20℃; for 1.5h;98%
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 18h; Inert atmosphere;84%
at 20℃; Inert atmosphere;78.3%
4-isopropylbenzenesulfonyl chloride
54997-90-9

4-isopropylbenzenesulfonyl chloride

6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

4-isopropyl-benzenesulfonic acid 6-chloro-pyridin-3-yl ester
898839-75-3

4-isopropyl-benzenesulfonic acid 6-chloro-pyridin-3-yl ester

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran at 20℃; for 2h;98%
6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

6-bromonicotinaldehyde
149806-06-4

6-bromonicotinaldehyde

6-(6-chloro-pyridin-3-yloxy)-pyridine-3-carbaldehyde
926313-06-6

6-(6-chloro-pyridin-3-yloxy)-pyridine-3-carbaldehyde

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 130℃; for 2h;98%
6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

methyl N-(chloroacetyl)anthranilate
58915-18-7

methyl N-(chloroacetyl)anthranilate

methyl 2-({[(6-chloro-3-pyridinyl)oxy]acetyl}amino)benzoate
845890-30-4

methyl 2-({[(6-chloro-3-pyridinyl)oxy]acetyl}amino)benzoate

Conditions
ConditionsYield
With caesium carbonate In acetonitrile for 6.33333h;97%
Cyclopentyl bromide
137-43-9

Cyclopentyl bromide

6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

2-chloro-5-cyclopentyloxypyridine
1204483-44-2

2-chloro-5-cyclopentyloxypyridine

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 20℃; for 5h;97%
2-(morpholin-4-yl)ethanol
622-40-2

2-(morpholin-4-yl)ethanol

6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

4-(2-((6-chloropyridin-3-yl)oxy)ethyl)morpholine
879487-97-5

4-(2-((6-chloropyridin-3-yl)oxy)ethyl)morpholine

Conditions
ConditionsYield
With triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran at 20℃; for 4h;97%
6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

trifluoromethylsulfonic anhydride
358-23-6

trifluoromethylsulfonic anhydride

6-chloropyridin-3-yl trifluoromethanesulfonate

6-chloropyridin-3-yl trifluoromethanesulfonate

Conditions
ConditionsYield
With triethylamine In dichloromethane at -12℃;96%
Stage #1: 6-chloropyridine-3-ol With triethylamine In dichloromethane at 20℃; for 0.0833333h; Inert atmosphere;
Stage #2: trifluoromethylsulfonic anhydride In dichloromethane at -78 - 20℃; for 12h; Inert atmosphere;
93%
With pyridine In dichloromethane at 0 - 20℃; for 16h; Sealed tube; Inert atmosphere;75%
6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

6-chloro-1-isopropyl-5-methyl-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one
90561-70-9

6-chloro-1-isopropyl-5-methyl-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

6-((6-chloropyridin-3-yl)oxy)-1-isopropyl-5-methyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one

6-((6-chloropyridin-3-yl)oxy)-1-isopropyl-5-methyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 85℃; for 18h;96%
6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

C14H8F4N4O3

C14H8F4N4O3

C19H11ClF3N5O4

C19H11ClF3N5O4

Conditions
ConditionsYield
With dmap In dichloromethane at 20℃;96%
6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

3-methyl-1-(methyldithiocarbonyl)imidazolium iodide

3-methyl-1-(methyldithiocarbonyl)imidazolium iodide

S-methyl 2-chloropyridine-5-dithiocarbamate
1258190-69-0

S-methyl 2-chloropyridine-5-dithiocarbamate

Conditions
ConditionsYield
With triethylamine In acetonitrile at 0℃; for 1h; Inert atmosphere;94%
6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

2-Fluorobenzaldehyde
446-52-6

2-Fluorobenzaldehyde

2-(6-chloro-pyridin-3-yloxy)-benzaldehyde
745828-11-9

2-(6-chloro-pyridin-3-yloxy)-benzaldehyde

Conditions
ConditionsYield
With potassium carbonate; copper In DMF (N,N-dimethyl-formamide) at 120℃; for 6h;93%
6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

3-fluoropropyl tosylate
312-68-5

3-fluoropropyl tosylate

2-chloro-5-(3-fluoropropoxy)pyridine

2-chloro-5-(3-fluoropropoxy)pyridine

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 85℃; for 5h; Inert atmosphere;93%
With caesium carbonate In N,N-dimethyl-formamide at 85℃; for 5h; Inert atmosphere;93%
6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

methyl chloroacetate
96-34-4

methyl chloroacetate

C8H8ClNO3
928118-49-4

C8H8ClNO3

Conditions
ConditionsYield
With potassium carbonate In acetone at 60℃; for 4h;92%
6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

2-fluoroethyl tosylate
383-50-6

2-fluoroethyl tosylate

2-chloro-5-(2-fluoroethoxy)pyridine

2-chloro-5-(2-fluoroethoxy)pyridine

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 85℃; for 5h; Inert atmosphere;92%
With caesium carbonate In N,N-dimethyl-formamide at 85℃; for 5h; Inert atmosphere;92%
6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

5-nitro-2-fluorotoluene
455-88-9

5-nitro-2-fluorotoluene

2-chloro-5-(2-methyl-4-nitrophenoxy)pyridine

2-chloro-5-(2-methyl-4-nitrophenoxy)pyridine

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 70℃; for 16h;91%
With potassium carbonate In N,N-dimethyl-formamide at 50℃; for 16h;
ethyl 2-bromoisobutyrate
600-00-0

ethyl 2-bromoisobutyrate

6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

ethyl 2-(6-chloropyridin-3-yloxy)-2-methylpropanoate
1360056-04-7

ethyl 2-(6-chloropyridin-3-yloxy)-2-methylpropanoate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 85℃;91%
With caesium carbonate In acetonitrile for 48h;
With caesium carbonate In acetonitrile for 48h; Inert atmosphere;51.1 g
6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

(R)-1-t-butyloxycarbonyl-2-azetidinemethanol
161511-90-6

(R)-1-t-butyloxycarbonyl-2-azetidinemethanol

2-chloro-5-((1-(tert-butoxycarbonyl))-2-(R)-azetidinylmethoxy)pyridine
209328-50-7

2-chloro-5-((1-(tert-butoxycarbonyl))-2-(R)-azetidinylmethoxy)pyridine

Conditions
ConditionsYield
With di-isopropyl azodicarboxylate; triphenylphosphine In tetrahydrofuran at 20℃; for 4h;90%
With triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran for 4h; Ambient temperature;
6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

ethyl bromoacetate
105-36-2

ethyl bromoacetate

(6-Chloro-pyridin-3-yloxy)-acetic acid ethyl ester
1005171-59-4

(6-Chloro-pyridin-3-yloxy)-acetic acid ethyl ester

Conditions
ConditionsYield
With caesium carbonate In acetonitrile at 20℃;90%
6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

6,7-dimethoxy-4-chloroquinazoline
13790-39-1

6,7-dimethoxy-4-chloroquinazoline

4-((6-chloropyridin-3-yl)oxy)-6,7-dimethoxyquinazoline
871690-77-6

4-((6-chloropyridin-3-yl)oxy)-6,7-dimethoxyquinazoline

Conditions
ConditionsYield
With dmap In dimethyl sulfoxide at 80℃; for 3h;90%
Stage #1: 6-chloropyridine-3-ol With potassium tert-butylate In tetrahydrofuran at 20℃; for 0.25h;
Stage #2: 6,7-dimethoxy-4-chloroquinazoline In tetrahydrofuran; dimethyl sulfoxide at 75℃; for 2h;
Stage #3: With water In tetrahydrofuran; dimethyl sulfoxide
83%
With dmap In dimethyl sulfoxide at 20 - 80℃; for 2h; Inert atmosphere;9.1g
With dmap In dimethyl sulfoxide at 80℃; for 2h; Inert atmosphere;9.1 g
6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

amyl iodide
628-17-1

amyl iodide

2-chloro-5-(pentyloxy)pyridine

2-chloro-5-(pentyloxy)pyridine

Conditions
ConditionsYield
With potassium carbonate In acetone for 16h; Reflux; Inert atmosphere;90%
6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

ethyl iodide
75-03-6

ethyl iodide

2-chloro-5-ethoxypyridine
856851-48-4

2-chloro-5-ethoxypyridine

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 0 - 40℃; for 2h;90%
6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

6-chloro-N-methoxy-N-methyl-4-(trifluoromethyl)pyridine-3-carboxamide

6-chloro-N-methoxy-N-methyl-4-(trifluoromethyl)pyridine-3-carboxamide

6-[(6-chloro-3-pyridyl)oxy]-N-methoxy-N-methyl-4-(trifluoromethyl)pyridine-3-carboxamide

6-[(6-chloro-3-pyridyl)oxy]-N-methoxy-N-methyl-4-(trifluoromethyl)pyridine-3-carboxamide

Conditions
ConditionsYield
With copper(l) iodide; N,N,N,N,-tetramethylethylenediamine; potassium carbonate In dimethylsulfoxide-d6 at 100℃; for 2h;89%
6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

neopentyl iodide
15501-33-4

neopentyl iodide

2-chloro-5-(2,2-dimethylpropoxy)pyridine
1154030-27-9

2-chloro-5-(2,2-dimethylpropoxy)pyridine

Conditions
ConditionsYield
With caesium carbonate In diethylene glycol dimethyl ether at 160℃; for 4h; microwave irradiation;88%
With caesium carbonate In diethylene glycol dimethyl ether at 160℃; for 4h; Microwave irradiation;88%
6-chloropyridine-3-ol
41288-96-4

6-chloropyridine-3-ol

4-fluoroboronic acid
1765-93-1

4-fluoroboronic acid

6-(4-fluorophenyl)pyridin-3-ol
31776-87-1

6-(4-fluorophenyl)pyridin-3-ol

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; caesium carbonate In 1,4-dioxane; water at 16℃; Inert atmosphere;86%

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