As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch
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inquiry1-Methylpiperidin-4-amine Basic information Product Name: 1-Methylpiperidin-4-amine Synonyms: 4-AMINO-1-METHYLPIPERDINE, 98.5%;1-Methylpiperidin-4-amine;1-(5-BROMOPYRIMIDIN-2-YL)[1,4]DIAZEPANE;4-Amino-1-methylpiperdine;1-Methyl-4-Amino Piperidi
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inquiry1-Methylpiperidin-4-amine Basic information Product Name: 1-Methylpiperidin-4-amine Synonyms: 1-(5-BROMOPYRIMIDIN-2-YL)[1,4]DIAZEPANE;4-Amino-1-methylpiperdine;1-Methyl-4-Amino Piperidin
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inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
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inquiryProduct Name: 1-Methylpiperidin-4-amine CAS: 41838-46-4 MF: C6H14N2 MW: 114.19 EINECS: 628-217-1 Mol File: 41838-46-4.mol 1-Methylpiperidin-4-amine Structure 1-Methylpiperidin-4-amine Chemical Properties Melting point 203-207
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inquiry1-Methylpiperidin-4-amine CAS:41838-46-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organi
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inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia
Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
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inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
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inquiryA substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc
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inquiryChemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff
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inquiryWe are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov
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inquiryProduct Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,
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Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W
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inquiry1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer
Cas:41838-46-4
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inquiryProductName:4-Amino-1-methylpiperidine Synonyms:1-methyl-4-piperidinamine;1-methyl-piperidin-4-ylamine;1-methylpiperidin-4-ylamine;1-methyl-4-amino-piperidine;4-amino-N-methylpiperidine;4-Amino-1-Methylpiperidine;1-methylpiperidin-4-amine;1-methy
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inquiryLocated in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service and h
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We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp
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inquiryShanghai Finebiotech Co.,Ltd.was established in 2020, which providing professional chemical services. As a customer-oriented company, we have distinguished ourself from others in providing worldwide customers with cost-effective and efficient service
Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai
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inquiryLower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe
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inquiryAcmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea
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inquiryhigh quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea
Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS
1-Methyl-4-piperidone
1-methyl-4-aminopiperidine
Conditions | Yield |
---|---|
With ammonium formate; palladium on carbon In methanol | 100% |
With ammonium formate; palladium on activated charcoal In methanol; water at 20℃; | 75% |
With ammonium formate; palladium on activated charcoal In methanol; water at 20℃; | 37% |
1-methylpiperidin-4-one hydrochloride
1-methyl-4-aminopiperidine
Conditions | Yield |
---|---|
Stage #1: 1-methylpiperidin-4-one hydrochloride With ammonium acetate In methanol for 0.166667h; Stage #2: With sodium cyanoborohydride In methanol for 1h; | 88% |
With ammonium acetate; sodium cyanoborohydride In methanol for 1.16667h; | 88% |
1-methyl-4-aminopiperidine
Conditions | Yield |
---|---|
With sodium tetrahydroborate at 5℃; for 12h; Reflux; Large scale; | 85.3% |
N-((4-methylphenyl)methyl)-N-(1-piperidin-4-yl)-4-chlorophenylacetamide
1-methyl-4-aminopiperidine
Conditions | Yield |
---|---|
With formic acid; palladium 10% on activated carbon In methanol for 24h; Heating / reflux; | 51% |
4-(4-methoxybenzylamino)-1-methylpiperidine
1-methyl-4-aminopiperidine
Conditions | Yield |
---|---|
With formic acid; palladium 10% on activated carbon In methanol for 24h; Inert atmosphere; Reflux; | 51% |
1-methyl-piperidin-4-one oxime ; hydrochloride
1-methyl-4-aminopiperidine
Conditions | Yield |
---|---|
With ethanol; sodium Heating; | 50% |
Conditions | Yield |
---|---|
With sodium |
1-methyl-4-piperidinone oxime
1-methyl-4-aminopiperidine
Conditions | Yield |
---|---|
With i-Amyl alcohol; sodium |
N-(1-methyl-[4]piperidyl)-acetamide
1-methyl-4-aminopiperidine
Conditions | Yield |
---|---|
With hydrogenchloride |
1-methylpiperidine-4-carboxamide
1-methyl-4-aminopiperidine
Conditions | Yield |
---|---|
With potassium hydroxide; bromine |
1-methyl-4-oxo-piperidine-3-carboxylic acid methyl ester
1-methyl-4-aminopiperidine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: water; hydrochloric acid 3: isopentyl alcohol; sodium View Scheme |
Conditions | Yield |
---|---|
With hydrogenchloride; NaCNBH3; silica gel In methanol; diethyl ether | 3.88 g (88%) |
With hydrogenchloride; NaCNBH3; silica gel In methanol; diethyl ether | 3.88 g (88%) |
4-chlorocarbonyl-4,9-dihydro-1-methyl-10H-thieno[3,4-b][1,5]benzodiazepin-10-one
A
1-methyl-4-aminopiperidine
4-(chlorocarbonyl)-4,9-dihydro-3-methyl-10H-thieno[3,4-b][1,5]benzodiazepin-10-one
A
1-methyl-4-aminopiperidine
4-(chlorocarbonyl)-4,9-dihydro-1,3-dimethyl-10H-thieno[3,4-b][1,5]benzodiazepin-10-one
A
1-methyl-4-aminopiperidine
1-(trifluoroacetyl)-4-piperidone
1-methyl-4-aminopiperidine
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1.1: sodium cyanoborohydride; acetic acid / methanol / 20 h / pH ~ 5 1.2: pH ~ 10 2.1: triethylamine / dichloromethane / 0.17 h / 0 °C 2.2: 1.25 h / 0 °C 3.1: potassium carbonate / methanol / 24 h / 40 °C 4.1: formic acid / palladium 10% on activated carbon / methanol / 24 h / Heating / reflux View Scheme |
4-(4-methylbenzylamino)-1-(trifluoroacetyl)piperidine
1-methyl-4-aminopiperidine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: triethylamine / dichloromethane / 0.17 h / 0 °C 1.2: 1.25 h / 0 °C 2.1: potassium carbonate / methanol / 24 h / 40 °C 3.1: formic acid / palladium 10% on activated carbon / methanol / 24 h / Heating / reflux View Scheme |
2-(4-chlorophenyl)-N-(4-methylbenzyl)-N-(1-trifluoroacetylpiperidin-4-yl)acetamide
1-methyl-4-aminopiperidine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: potassium carbonate / methanol / 24 h / 40 °C 2: formic acid / palladium 10% on activated carbon / methanol / 24 h / Heating / reflux View Scheme |
tert-butyl 4-((4-methylphenyl)methyl)aminopiperidine carboxylate
1-methyl-4-aminopiperidine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 20 h / 20 °C 1.2: 2 h 2.1: hydrogenchloride / 1,4-dioxane; diethyl ether / 2 h / 20 °C 3.1: formic acid / palladium 10% on activated carbon / methanol / 24 h / Heating / reflux View Scheme |
1-methyl-4-aminopiperidine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: hydrogenchloride / 1,4-dioxane; diethyl ether / 2 h / 20 °C 2: formic acid / palladium 10% on activated carbon / methanol / 24 h / Heating / reflux View Scheme |
4-piperidone hydrochloride
1-methyl-4-aminopiperidine
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1.1: triethylamine / dichloromethane / 0.17 h / 0 °C 1.2: 2 h / 20 °C 2.1: sodium cyanoborohydride; acetic acid / methanol / 20 h / pH ~ 5 2.2: pH ~ 10 3.1: triethylamine / dichloromethane / 0.17 h / 0 °C 3.2: 1.25 h / 0 °C 4.1: potassium carbonate / methanol / 24 h / 40 °C 5.1: formic acid / palladium 10% on activated carbon / methanol / 24 h / Heating / reflux View Scheme |
N-tert-butyloxycarbonylpiperidin-4-one
1-methyl-4-aminopiperidine
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1.1: sodium cyanoborohydride; acetic acid / methanol / 20 h / 20 °C 1.2: 1 h 2.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 20 h / 20 °C 2.2: 2 h 3.1: hydrogenchloride / 1,4-dioxane; diethyl ether / 2 h / 20 °C 4.1: formic acid / palladium 10% on activated carbon / methanol / 24 h / Heating / reflux View Scheme |
1-methyl-4-aminopiperidine
2‐fluoro‐5‐methoxy‐4‐nitrobenzoic acid
2-fluoro-5-methoxy-N-(1-methylpiperidin-4-yl)-4-nitrobenzamide
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine; HATU In ISOPROPYLAMIDE at 18 - 25℃; for 1h; | 100% |
With N-ethyl-N,N-diisopropylamine; HATU In N,N-dimethyl acetamide at 18 - 25℃; for 1h; | 100% |
1-methyl-4-aminopiperidine
4-amino-3-fluorobenzoic acid
4-amino-3-fluoro-N-(1-methylpiperidin-4-yl)benzamide
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine; HATU In N,N-dimethyl-formamide at 18 - 25℃; for 18h; | 100% |
With N-ethyl-N,N-diisopropylamine; HATU In N,N-dimethyl acetamide at 18 - 25℃; for 18h; | 100% |
1-methyl-4-aminopiperidine
2-fluoro-4-bromobenzoic acid
4-bromo-2-fluoro-N-(1-methylpiperidin-4-yl)benzamide
Conditions | Yield |
---|---|
Stage #1: 4-Amino-1-methylpiperidine; 2-fluoro-4-bromobenzoic acid With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 1.5h; Stage #2: With sodium hydroxide In water at 20℃; | 100% |
With triethylamine; HATU In N,N-dimethyl-formamide |
1-methyl-4-aminopiperidine
7-(benzyloxy)-2,4-dichloro-6-methoxyquinazoline
7-(benzyloxy)-2-chloro-6-methoxy-N-(1-methylpiperidin-4-yl)quinazolin-4-amine
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 20℃; | 100% |
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 20℃; | 100% |
at 20℃; |
1-methyl-4-aminopiperidine
5-amino-4-methyl-1-phenyl-1H-pyrazole-3-carboxylic acid
5-amino-4-methyl-N-(1-methylpiperidin-4-yl)-1-phenyl-1H-pyrazole-3-carboxamide
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine; HATU In N,N-dimethyl-formamide at 20℃; for 5.5h; | 100% |
1-methyl-4-aminopiperidine
Conditions | Yield |
---|---|
With potassium fluoride In dimethyl sulfoxide at 120℃; for 1h; | 100% |
1-methyl-4-aminopiperidine
N-(5-bromo-4-chloropyridin-2-yl)pivalamide
N-(5-bromo-4-(1-methylpiperidin-4-ylamino)pyridin-2-yl)pivalamide
Conditions | Yield |
---|---|
In 1-methyl-pyrrolidin-2-one at 220℃; for 3h; Microwave irradiation; | 99% |
1-methyl-4-aminopiperidine
1-bromo-3-nitro-5-(trifluoromethyl)benzene
1-methyl-N-[3-nitro-5-(trifluoromethyl)phenyl]piperidin-4-amine
Conditions | Yield |
---|---|
With palladium diacetate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In 1,4-dioxane at 120℃; Inert atmosphere; | 99% |
With palladium diacetate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In 1,4-dioxane at 120℃; Inert atmosphere; | 99% |
1-methyl-4-aminopiperidine
4-Bromo-1-fluoro-2-nitrobenzene
Conditions | Yield |
---|---|
With triethylamine In tetrahydrofuran at 0 - 20℃; Inert atmosphere; | 99% |
With caesium carbonate In N,N-dimethyl-formamide at 20℃; for 8h; |
1-methyl-4-aminopiperidine
6-bromo-4-chloro-3-quinolinecarbonitrile
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In isopropyl alcohol at 100℃; for 0.5h; Microwave irradiation; | 99% |
1-methyl-4-aminopiperidine
N-(1-methyl-piperidin-4-yl)-N'-[4-(4,4,5,5-tetramethyl-1,3,2-dioxoborolan-2-yl)-phenyl]-urea
Conditions | Yield |
---|---|
In dichloromethane at 20℃; for 5h; | 98% |
In 1,2-dimethoxyethane |
1-methyl-4-aminopiperidine
3-methyl-4-nitrobenzoic acid
3-methyl-N-(1-methyl-4-piperidyI)-4-nitro-benzamide
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine; HATU In N,N-dimethyl-formamide at 18 - 25℃; for 18h; | 98% |
1-methyl-4-aminopiperidine
3-chloro-5-hydroxybenzaldehyde
Conditions | Yield |
---|---|
With sodium tris(acetoxy)borohydride In dichloromethane at 20℃; for 18.5h; | 97% |
1-methyl-4-aminopiperidine
ortho-nitrofluorobenzene
N-(1-methyl-piperidin-4-yl)-benzene-1,2-diamine
Conditions | Yield |
---|---|
96% |
1-methyl-4-aminopiperidine
5-(1,1-difluoroethyl)-2-methyl-2H-pyrazole-3-carboxylic acid
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In 1-methyl-pyrrolidin-2-one at 90℃; for 0.166667h; Microwave irradiation; | 96% |
1-methyl-4-aminopiperidine
Conditions | Yield |
---|---|
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine In N,N-dimethyl-formamide at 20℃; for 16h; Inert atmosphere; | 96% |
1-methyl-4-aminopiperidine
methyl 2-isothiocyanatobenzoate
Conditions | Yield |
---|---|
With triethylamine In tetrahydrofuran at 150℃; for 0.75h; Microwave irradiation; | 96% |
1-methyl-4-aminopiperidine
2-Fluoro-5-nitrobenzotrifluoride
(1-methyl-piperidin-4-yl)-(4-nitro-2-trifluoromethyl-phenyl)-amine
Conditions | Yield |
---|---|
In tetrahydrofuran at 20℃; for 4h; | 95% |
1-methyl-4-aminopiperidine
5-bromo-2-methoxypyridine-3-carboxaldehyde
Conditions | Yield |
---|---|
With sodium cyanoborohydride; acetic acid In methanol at 20℃; for 22h; | 94% |
1-methyl-4-aminopiperidine
3-fluoro-4-nitrobenzoic acid
Conditions | Yield |
---|---|
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine In N,N-dimethyl-formamide at 20℃; for 16h; Inert atmosphere; | 94% |
1-methyl-4-aminopiperidine
3,4,5-Trimethoxybenzoyl chloride
Conditions | Yield |
---|---|
In benzene Ambient temperature; | 93% |
1-methyl-4-aminopiperidine
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine; HATU In N,N-dimethyl-formamide at 0 - 20℃; for 4h; Inert atmosphere; | 92.4% |
1-methyl-4-aminopiperidine
4-methyl-benzoyl chloride
Conditions | Yield |
---|---|
In benzene Ambient temperature; | 92% |
1-methyl-4-aminopiperidine
2-chloro-6,7-dimethoxy-3H-quinazolin-4-one
2-chloro-6,7-dimethoxy-N-(1-methylpiperidin-4-yl)quinazolin-4-amine
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 20℃; for 2h; | 92% |
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 20℃; for 2h; | 92% |
With potassium carbonate In N,N-dimethyl-formamide at 20℃; | 90% |
1-methyl-4-aminopiperidine
4-nitro-benzoic acid
N-(1-methylpiperidin-4-yl)-4-nitrobenzamide
Conditions | Yield |
---|---|
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine In N,N-dimethyl-formamide at 20℃; for 16h; Inert atmosphere; | 92% |
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 0 - 20℃; | 17.39% |
With N-ethyl-N,N-diisopropylamine; HATU In N,N-dimethyl-formamide at 35℃; for 4h; |
1-methyl-4-aminopiperidine
Conditions | Yield |
---|---|
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In 1,4-dioxane at 20℃; for 24h; | 92% |
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In 1,4-dioxane at 20℃; for 24h; Inert atmosphere; | 92% |
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 70℃; for 16h; | 92% |
cyclohexanylcarbonyl chloride
Conditions | Yield |
---|---|
In benzene Ambient temperature; | 91% |
1-methyl-4-aminopiperidine
3',4',5'-trimethoxycinnamoyl chloride
Conditions | Yield |
---|---|
In benzene Ambient temperature; | 91% |
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