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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Content Natural Extract Wedelolactone HACCP manufacturer

Cas:524-12-9

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem’s R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. Near 20 years DayangChem has provided dif

WEDELOLACTONE

Cas:524-12-9

Min.Order:1 Kilogram

FOB Price: $1.0 / 2.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

WEDELOLACTONE

Cas:524-12-9

Min.Order:1 Kilogram

FOB Price: $3.0 / 10.0

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Henan Tianfu Chemical Co., Ltd. is located in Zhengzhou High-tech Development Zone with import and export license. We passed ISO 9001:2008 in 2009, and won "High-tech Enterprise" by provincial government in 2013.The objective of the com

TIANFU-CHEM - WEDELOLACTONE

Cas:524-12-9

Min.Order:1 Gram

FOB Price: $1000.0

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 524-12-9 with competitive price

Cas:524-12-9

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Product Name Wedelolactone Molecular formula C16H10O7 CAS 524-12-9 Molecular Weight 314.249 HPLC 98% Grade

Wedelolactone

Cas:524-12-9

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

6H-Benzofuro[3,2-c][1]benzopyran-6-one,1,8,9-trihydroxy-3-methoxy- 524-12-9

Cas:524-12-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Wedelolactone 99%

Cas:524-12-9

Min.Order:1 Kilogram

FOB Price: $30.0 / 40.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

WEDELOLACTONE CAS:524-12-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates

WEDELOLACTONE CAS:524-12-9

Cas:524-12-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

6H-Benzofuro[3,2-c][1]benzopyran-6-one,1,8,9-trihydroxy-3-methoxy-

Cas:524-12-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

WEDELOLACTONE

Cas:524-12-9

Min.Order:1 Kilogram

FOB Price: $10.0 / 30.0

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

6H-Benzofuro[3,2-c][1]benzopyran-6-one,1,8,9-trihydroxy-3-methoxy-

Cas:524-12-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chengdu Biopurify Phytochemicals Ltd.

Chengdu Biopurify Phytochemicals Ltd. is a leading company in the research, development, manufacture and marketing of High Quality Phytochemicals and Extracts(especially Active Ingredients from Traditional Chinese Medicine,Traditional Chinese Medic

Wedelolactone

Cas:524-12-9

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Triumph International Development Limilted

Triumph has the complete production of G- KG - MT service chain,we can make the new technology into productivity quickly in the research and development of new products. Main Business Custom Synthesis: Trading(Raw Mater

WEDELOLACTONE

Cas:524-12-9

Min.Order:0 Metric Ton

FOB Price: $18.0 / 20.0

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

WEDELOLACTONE

Cas:524-12-9

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply WEDELOLACTONE

Cas:524-12-9

Min.Order:0 Metric Ton

Negotiable

Type:Other

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

6H-Benzofuro[3,2-c][1]benzopyran-6-one,1,8,9-trihydroxy-3-methoxy-

Cas:524-12-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shaanxi Cuicheng Biomedical Technology Co., Ltd.

Why Choose Us: 1. Factory direct sales, so we can provide the competitive price and high quality product base on 8 years of production and R&D experience. 2. It is available in stock for quick shipment.Products could be packaged according to cu

WEDELOLACTONE

Cas:524-12-9

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

Wedelolactone

Cas:524-12-9

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

WedelolactoneAppearance:Yellow powder Package:according to customers' requirements Application:research use Transportation:By air(EMS or EUB or FedEx or TNT ect...) or by sea(FOB or CIF or CNF ect...)or according to your demand. Port:Any port

Wedelolactone

Cas:524-12-9

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Best OfferWEDELOLACTONE

Cas:524-12-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

Wedelolactone

Cas:524-12-9

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

WEDELOLACTONE

Cas:524-12-9

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

WEDELOLACTONE

Cas:524-12-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

WEDELOLACTONE

Cas:524-12-9

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

7-Methoxy-5,11,12-trihydroxycoumestan

Cas:524-12-9

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

shanghai Tauto Biotech Co., Ltd

The quality is guaranteed. If you find the product is wrong compared with COA, we promise 100% refund or change product. COA and HPLC will be shipped out with goods. You can also inform your analysis method and we will follow your analysis me

E-0695 Wedelolactone

Cas:524-12-9

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

WEDELOLACTONE

Cas:524-12-9

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

WEDELOLACTONE

Cas:524-12-9

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Hebei Mojin Biotechnology Co.,Ltd

We produce carbomer by our own factory,carbomer 940 is our best seller.It is used for cosmetic and medical.And we also become agent for lubrizol.Our carbomer 940 get high viscosity and good transparency.The price will depond on the market,surely supp

6H-Benzofuro[3,2-c][1]benzopyran-6-one,1,8,9-trihydroxy-3-methoxy-

Cas:524-12-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

2-(2,6-dihydroxy-4-methoxy-phenyl)-5,6-dihydroxy-benzofuran-3-carboxylic acid methyl ester
627489-05-8

2-(2,6-dihydroxy-4-methoxy-phenyl)-5,6-dihydroxy-benzofuran-3-carboxylic acid methyl ester

wedelolactone
524-12-9

wedelolactone

Conditions
ConditionsYield
With sulfuric acid; acetic acid In water at 50℃; for 1h;93%
1-hydroxy-3-methoxy-8,9-diisopropyloxy-benzo[4,5]furo[3,2-c]chromen-6-one
1023744-97-9

1-hydroxy-3-methoxy-8,9-diisopropyloxy-benzo[4,5]furo[3,2-c]chromen-6-one

wedelolactone
524-12-9

wedelolactone

Conditions
ConditionsYield
With boron trichloride In dichloromethane at 0℃;87%
1,8,9-tris(benzyloxy)-3-methoxy-6H-benzofuro[3,2-c]chromen-6-one
115623-32-0

1,8,9-tris(benzyloxy)-3-methoxy-6H-benzofuro[3,2-c]chromen-6-one

wedelolactone
524-12-9

wedelolactone

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In 1,4-dioxane Product distribution; 2nd step of purification of 9 (wedelolactone);82%
With boron trichloride In dichloromethane at 0℃; Inert atmosphere;81%
4,5-dihydroxy-7-methoxy coumarin
67964-24-3

4,5-dihydroxy-7-methoxy coumarin

benzene-1,2-diol
120-80-9

benzene-1,2-diol

wedelolactone
524-12-9

wedelolactone

Conditions
ConditionsYield
With sodium acetate; potassium hexacyanoferrate(III) In water; acetone for 2h; Ambient temperature;25%
With ascorbic acid 1.) tyrosinase, pH=6.8, r.t., 1 h; Yield given. Multistep reaction;
tri-O-methyl-wedelolactone

tri-O-methyl-wedelolactone

wedelolactone
524-12-9

wedelolactone

Conditions
ConditionsYield
With hydrogen iodide
3,4-dibenzyloxybenzaldehyde
5447-02-9

3,4-dibenzyloxybenzaldehyde

wedelolactone
524-12-9

wedelolactone

Conditions
ConditionsYield
Multi-step reaction with 8 steps
1.1: m-chloroperbenzoic acid / CH2Cl2; H2O / 15 h / 20 °C
1.2: 90 percent / K2CO3 / methanol / 0.5 h / 25 °C
2.1: 99 percent / Et3N / tetrahydrofuran / 2 h / 25 °C
3.1: 94 percent / N-iodosuccinimide; trifluoroacetic acid / acetonitrile / 12 h / 40 °C
4.1: 90 percent / CuI; Et3N / PdCl2(PPh3)2 / acetonitrile / 12 h / 25 °C
5.1: 98 percent / hydrazine monohydrate / tetrahydrofuran / 2 h / 25 °C
6.1: 87 percent / thiourea; Cs2CO3; CBr4 / PdI2 / tetrahydrofuran / 2 h / 50 °C
7.1: 93 percent / H2 / Pd/C / ethyl acetate / 24 h / 25 °C
8.1: 93 percent / AcOH; H2SO4 / H2O / 1 h / 50 °C
View Scheme
Multi-step reaction with 8 steps
1.1: 3-chloro-benzenecarboperoxoic acid / water; dichloromethane / 15 h / 20 °C
1.2: 0.5 h / 20 °C
2.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 0 °C
2.2: 20 °C
3.1: N-Bromosuccinimide / N,N-dimethyl-formamide / 4.5 h / 0 - 20 °C
4.1: triethylamine; bis-triphenylphosphine-palladium(II) chloride / tetrahydrofuran / 80 °C / Inert atmosphere
5.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate / water; tetrahydrofuran / 12 h / 90 °C / Inert atmosphere
6.1: potassium carbonate / N,N-dimethyl-formamide
7.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / toluene / 24 h / Reflux
8.1: boron trichloride / dichloromethane / 0 °C / Inert atmosphere
View Scheme
3,4-dibenzyloxyphenol
27688-86-4

3,4-dibenzyloxyphenol

wedelolactone
524-12-9

wedelolactone

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1: 99 percent / Et3N / tetrahydrofuran / 2 h / 25 °C
2: 94 percent / N-iodosuccinimide; trifluoroacetic acid / acetonitrile / 12 h / 40 °C
3: 90 percent / CuI; Et3N / PdCl2(PPh3)2 / acetonitrile / 12 h / 25 °C
4: 98 percent / hydrazine monohydrate / tetrahydrofuran / 2 h / 25 °C
5: 87 percent / thiourea; Cs2CO3; CBr4 / PdI2 / tetrahydrofuran / 2 h / 50 °C
6: 93 percent / H2 / Pd/C / ethyl acetate / 24 h / 25 °C
7: 93 percent / AcOH; H2SO4 / H2O / 1 h / 50 °C
View Scheme
Multi-step reaction with 7 steps
1.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 0 °C
1.2: 20 °C
2.1: N-Bromosuccinimide / N,N-dimethyl-formamide / 4.5 h / 0 - 20 °C
3.1: triethylamine; bis-triphenylphosphine-palladium(II) chloride / tetrahydrofuran / 80 °C / Inert atmosphere
4.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate / water; tetrahydrofuran / 12 h / 90 °C / Inert atmosphere
5.1: potassium carbonate / N,N-dimethyl-formamide
6.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / toluene / 24 h / Reflux
7.1: boron trichloride / dichloromethane / 0 °C / Inert atmosphere
View Scheme
3,4-Dibenzyloxyphenyl-acetat
27688-85-3

3,4-Dibenzyloxyphenyl-acetat

wedelolactone
524-12-9

wedelolactone

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 94 percent / N-iodosuccinimide; trifluoroacetic acid / acetonitrile / 12 h / 40 °C
2: 90 percent / CuI; Et3N / PdCl2(PPh3)2 / acetonitrile / 12 h / 25 °C
3: 98 percent / hydrazine monohydrate / tetrahydrofuran / 2 h / 25 °C
4: 87 percent / thiourea; Cs2CO3; CBr4 / PdI2 / tetrahydrofuran / 2 h / 50 °C
5: 93 percent / H2 / Pd/C / ethyl acetate / 24 h / 25 °C
6: 93 percent / AcOH; H2SO4 / H2O / 1 h / 50 °C
View Scheme
2,6-bis(benzyloxy)-4-methoxybenzaldehyde
91360-58-6

2,6-bis(benzyloxy)-4-methoxybenzaldehyde

wedelolactone
524-12-9

wedelolactone

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: t-BuOK / tetrahydrofuran / 0.5 h / 0 °C
1.2: 75 percent / t-BuOK / tetrahydrofuran / 0 - 25 °C
2.1: 90 percent / CuI; Et3N / PdCl2(PPh3)2 / acetonitrile / 12 h / 25 °C
3.1: 98 percent / hydrazine monohydrate / tetrahydrofuran / 2 h / 25 °C
4.1: 87 percent / thiourea; Cs2CO3; CBr4 / PdI2 / tetrahydrofuran / 2 h / 50 °C
5.1: 93 percent / H2 / Pd/C / ethyl acetate / 24 h / 25 °C
6.1: 93 percent / AcOH; H2SO4 / H2O / 1 h / 50 °C
View Scheme
3,4-dihydroxybenzaldehyde
139-85-5

3,4-dihydroxybenzaldehyde

wedelolactone
524-12-9

wedelolactone

Conditions
ConditionsYield
Multi-step reaction with 9 steps
1.1: 94 percent / K2CO3; n-Bu4NI / acetone / 24 h / Heating
2.1: m-chloroperbenzoic acid / CH2Cl2; H2O / 15 h / 20 °C
2.2: 90 percent / K2CO3 / methanol / 0.5 h / 25 °C
3.1: 99 percent / Et3N / tetrahydrofuran / 2 h / 25 °C
4.1: 94 percent / N-iodosuccinimide; trifluoroacetic acid / acetonitrile / 12 h / 40 °C
5.1: 90 percent / CuI; Et3N / PdCl2(PPh3)2 / acetonitrile / 12 h / 25 °C
6.1: 98 percent / hydrazine monohydrate / tetrahydrofuran / 2 h / 25 °C
7.1: 87 percent / thiourea; Cs2CO3; CBr4 / PdI2 / tetrahydrofuran / 2 h / 50 °C
8.1: 93 percent / H2 / Pd/C / ethyl acetate / 24 h / 25 °C
9.1: 93 percent / AcOH; H2SO4 / H2O / 1 h / 50 °C
View Scheme
Multi-step reaction with 9 steps
1.1: potassium carbonate / N,N-dimethyl-formamide / 4 h / 20 °C
2.1: 3-chloro-benzenecarboperoxoic acid / water; dichloromethane / 15 h / 20 °C
2.2: 0.5 h / 20 °C
3.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 0 °C
3.2: 20 °C
4.1: N-Bromosuccinimide / N,N-dimethyl-formamide / 4.5 h / 0 - 20 °C
5.1: triethylamine; bis-triphenylphosphine-palladium(II) chloride / tetrahydrofuran / 80 °C / Inert atmosphere
6.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate / water; tetrahydrofuran / 12 h / 90 °C / Inert atmosphere
7.1: potassium carbonate / N,N-dimethyl-formamide
8.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / toluene / 24 h / Reflux
9.1: boron trichloride / dichloromethane / 0 °C / Inert atmosphere
View Scheme
1,3-Bis-benzyloxy-2-ethynyl-5-methoxy-benzene
627489-10-5

1,3-Bis-benzyloxy-2-ethynyl-5-methoxy-benzene

wedelolactone
524-12-9

wedelolactone

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 90 percent / CuI; Et3N / PdCl2(PPh3)2 / acetonitrile / 12 h / 25 °C
2: 98 percent / hydrazine monohydrate / tetrahydrofuran / 2 h / 25 °C
3: 87 percent / thiourea; Cs2CO3; CBr4 / PdI2 / tetrahydrofuran / 2 h / 50 °C
4: 93 percent / H2 / Pd/C / ethyl acetate / 24 h / 25 °C
5: 93 percent / AcOH; H2SO4 / H2O / 1 h / 50 °C
View Scheme
acetic acid 4,5-bis-benzyloxy-2-iodo-phenyl ester
627489-15-0

acetic acid 4,5-bis-benzyloxy-2-iodo-phenyl ester

wedelolactone
524-12-9

wedelolactone

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 90 percent / CuI; Et3N / PdCl2(PPh3)2 / acetonitrile / 12 h / 25 °C
2: 98 percent / hydrazine monohydrate / tetrahydrofuran / 2 h / 25 °C
3: 87 percent / thiourea; Cs2CO3; CBr4 / PdI2 / tetrahydrofuran / 2 h / 50 °C
4: 93 percent / H2 / Pd/C / ethyl acetate / 24 h / 25 °C
5: 93 percent / AcOH; H2SO4 / H2O / 1 h / 50 °C
View Scheme
4,5-bis-benzyloxy-2-(2,6-bis-benzyloxy-4-methoxy-phenylethynyl)-phenol
344303-12-4

4,5-bis-benzyloxy-2-(2,6-bis-benzyloxy-4-methoxy-phenylethynyl)-phenol

wedelolactone
524-12-9

wedelolactone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 87 percent / thiourea; Cs2CO3; CBr4 / PdI2 / tetrahydrofuran / 2 h / 50 °C
2: 93 percent / H2 / Pd/C / ethyl acetate / 24 h / 25 °C
3: 93 percent / AcOH; H2SO4 / H2O / 1 h / 50 °C
View Scheme
acetic acid 4,5-bis-benzyloxy-2-(2,6-bis-benzyloxy-4-methoxy-phenylethynyl)-phenyl ester
627489-61-6

acetic acid 4,5-bis-benzyloxy-2-(2,6-bis-benzyloxy-4-methoxy-phenylethynyl)-phenyl ester

wedelolactone
524-12-9

wedelolactone

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 98 percent / hydrazine monohydrate / tetrahydrofuran / 2 h / 25 °C
2: 87 percent / thiourea; Cs2CO3; CBr4 / PdI2 / tetrahydrofuran / 2 h / 50 °C
3: 93 percent / H2 / Pd/C / ethyl acetate / 24 h / 25 °C
4: 93 percent / AcOH; H2SO4 / H2O / 1 h / 50 °C
View Scheme
5,6-bis-benzyloxy-2-(2,6-bis-benzyloxy-4-methoxy-phenyl)-benzofuran-3-carboxylic acid methyl ester
344303-15-7

5,6-bis-benzyloxy-2-(2,6-bis-benzyloxy-4-methoxy-phenyl)-benzofuran-3-carboxylic acid methyl ester

wedelolactone
524-12-9

wedelolactone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 93 percent / H2 / Pd/C / ethyl acetate / 24 h / 25 °C
2: 93 percent / AcOH; H2SO4 / H2O / 1 h / 50 °C
View Scheme
3,5-dihydroxyphenol
108-73-6

3,5-dihydroxyphenol

wedelolactone
524-12-9

wedelolactone

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: hydrogenchloride / diethyl ether / 2 h
2: hydrogenchloride / 1 h / Heating
3: sodium carbonate / water / 1 h / 80 °C
4: ascorbic acid / 1.) tyrosinase, pH=6.8, r.t., 1 h
View Scheme
Multi-step reaction with 8 steps
1.1: zinc(II) chloride / 2 h / 100 °C
2.1: potassium carbonate / acetone / 1 h / 90 °C
2.2: 1.5 h / 90 °C
3.1: bromine / dichloromethane / 8 h / 0 - 10 °C
3.2: 1 h / 20 °C
4.1: potassium carbonate / acetone / 56 °C
5.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate / water; tetrahydrofuran / 12 h / 90 °C / Inert atmosphere
6.1: potassium carbonate / N,N-dimethyl-formamide
7.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / toluene / 24 h / Reflux
8.1: boron trichloride / dichloromethane / 0 °C / Inert atmosphere
View Scheme
4-amino-5,7-dihydroxycoumarin
162888-73-5

4-amino-5,7-dihydroxycoumarin

wedelolactone
524-12-9

wedelolactone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: hydrogenchloride / 1 h / Heating
2: sodium carbonate / water / 1 h / 80 °C
3: ascorbic acid / 1.) tyrosinase, pH=6.8, r.t., 1 h
View Scheme
4,5,7-trihydroxycoumarin
17575-26-7

4,5,7-trihydroxycoumarin

wedelolactone
524-12-9

wedelolactone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium carbonate / water / 1 h / 80 °C
2: ascorbic acid / 1.) tyrosinase, pH=6.8, r.t., 1 h
View Scheme
5-(benzyloxy)-3-(4,5-bis(benzyloxy)-2-((4-methoxybenzyl)oxy)phenyl)-7-methoxy-2-chromenone

5-(benzyloxy)-3-(4,5-bis(benzyloxy)-2-((4-methoxybenzyl)oxy)phenyl)-7-methoxy-2-chromenone

wedelolactone
524-12-9

wedelolactone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / toluene / 24 h / Reflux
2: boron trichloride / dichloromethane / 0 °C / Inert atmosphere
View Scheme
C34H37BO6

C34H37BO6

wedelolactone
524-12-9

wedelolactone

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate / water; tetrahydrofuran / 12 h / 90 °C / Inert atmosphere
2: potassium carbonate / N,N-dimethyl-formamide
3: 2,3-dicyano-5,6-dichloro-p-benzoquinone / toluene / 24 h / Reflux
4: boron trichloride / dichloromethane / 0 °C / Inert atmosphere
View Scheme
1,2-dibenzyloxy-4-(p-methoxybenzyl)oxybenzene

1,2-dibenzyloxy-4-(p-methoxybenzyl)oxybenzene

wedelolactone
524-12-9

wedelolactone

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: N-Bromosuccinimide / N,N-dimethyl-formamide / 4.5 h / 0 - 20 °C
2: triethylamine; bis-triphenylphosphine-palladium(II) chloride / tetrahydrofuran / 80 °C / Inert atmosphere
3: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate / water; tetrahydrofuran / 12 h / 90 °C / Inert atmosphere
4: potassium carbonate / N,N-dimethyl-formamide
5: 2,3-dicyano-5,6-dichloro-p-benzoquinone / toluene / 24 h / Reflux
6: boron trichloride / dichloromethane / 0 °C / Inert atmosphere
View Scheme
1,2-dibenzyloxy-4-bromo-5-(p-methoxybenzyl)oxybenzene

1,2-dibenzyloxy-4-bromo-5-(p-methoxybenzyl)oxybenzene

wedelolactone
524-12-9

wedelolactone

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: triethylamine; bis-triphenylphosphine-palladium(II) chloride / tetrahydrofuran / 80 °C / Inert atmosphere
2: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate / water; tetrahydrofuran / 12 h / 90 °C / Inert atmosphere
3: potassium carbonate / N,N-dimethyl-formamide
4: 2,3-dicyano-5,6-dichloro-p-benzoquinone / toluene / 24 h / Reflux
5: boron trichloride / dichloromethane / 0 °C / Inert atmosphere
View Scheme
5,7-dihydroxy-2H-chromen-2-one
2732-18-5

5,7-dihydroxy-2H-chromen-2-one

wedelolactone
524-12-9

wedelolactone

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1.1: potassium carbonate / acetone / 1 h / 90 °C
1.2: 1.5 h / 90 °C
2.1: bromine / dichloromethane / 8 h / 0 - 10 °C
2.2: 1 h / 20 °C
3.1: potassium carbonate / acetone / 56 °C
4.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate / water; tetrahydrofuran / 12 h / 90 °C / Inert atmosphere
5.1: potassium carbonate / N,N-dimethyl-formamide
6.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / toluene / 24 h / Reflux
7.1: boron trichloride / dichloromethane / 0 °C / Inert atmosphere
View Scheme
5,7-diacetoxyl-2-chromenone
21524-17-4

5,7-diacetoxyl-2-chromenone

wedelolactone
524-12-9

wedelolactone

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: bromine / dichloromethane / 8 h / 0 - 10 °C
1.2: 1 h / 20 °C
2.1: potassium carbonate / acetone / 56 °C
3.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate / water; tetrahydrofuran / 12 h / 90 °C / Inert atmosphere
4.1: potassium carbonate / N,N-dimethyl-formamide
5.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / toluene / 24 h / Reflux
6.1: boron trichloride / dichloromethane / 0 °C / Inert atmosphere
View Scheme
3-bromo-5,7-diacetoxyl-2-chromenone
1023744-89-9

3-bromo-5,7-diacetoxyl-2-chromenone

wedelolactone
524-12-9

wedelolactone

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: potassium carbonate / acetone / 56 °C
2: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate / water; tetrahydrofuran / 12 h / 90 °C / Inert atmosphere
3: potassium carbonate / N,N-dimethyl-formamide
4: 2,3-dicyano-5,6-dichloro-p-benzoquinone / toluene / 24 h / Reflux
5: boron trichloride / dichloromethane / 0 °C / Inert atmosphere
View Scheme
3-bromo-5-benzyloxy-7-acetoxyl-2-chromenone

3-bromo-5-benzyloxy-7-acetoxyl-2-chromenone

wedelolactone
524-12-9

wedelolactone

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate / water; tetrahydrofuran / 12 h / 90 °C / Inert atmosphere
2: potassium carbonate / N,N-dimethyl-formamide
3: 2,3-dicyano-5,6-dichloro-p-benzoquinone / toluene / 24 h / Reflux
4: boron trichloride / dichloromethane / 0 °C / Inert atmosphere
View Scheme
5-(benzyloxy)-3-(4,5-bis(benzyloxy)-2-((4-methoxybenzyl)oxy)phenyl)-7-hydroxy-2-chromenone

5-(benzyloxy)-3-(4,5-bis(benzyloxy)-2-((4-methoxybenzyl)oxy)phenyl)-7-hydroxy-2-chromenone

wedelolactone
524-12-9

wedelolactone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: potassium carbonate / N,N-dimethyl-formamide
2: 2,3-dicyano-5,6-dichloro-p-benzoquinone / toluene / 24 h / Reflux
3: boron trichloride / dichloromethane / 0 °C / Inert atmosphere
View Scheme
wedelolactone
524-12-9

wedelolactone

benzyl chloride
100-44-7

benzyl chloride

1,8,9-tris(benzyloxy)-3-methoxy-6H-benzofuro[3,2-c]chromen-6-one
115623-32-0

1,8,9-tris(benzyloxy)-3-methoxy-6H-benzofuro[3,2-c]chromen-6-one

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide for 0.833333h; Heating;29%
wedelolactone
524-12-9

wedelolactone

acetyl chloride
75-36-5

acetyl chloride

wedelolactone triacetate
6468-54-8

wedelolactone triacetate

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran at 25℃; for 2h;

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