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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

2,2,6-Trimethyl-4H-1,3-dioxin-4-one Manufacturer/High quality/Best price/In stock

Cas:5394-63-8

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 2,2,6-trimethyl-4H-1,3-dioxin-4-one

Cas:5394-63-8

Min.Order:1

Negotiable

Type:Other

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2,2,6-Trimethyl-4H-1,3-dioxin-4-one

Cas:5394-63-8

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

CAS 5394-63-8 2,2,6-Trimethyl-4H-1,3-dioxin-4-one

Cas:5394-63-8

Min.Order:1 Kilogram

FOB Price: $1000.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

2, 2, 6-Trimethyl-4h-1, 3-Dioxin-4-One CAS No. 5394-63-8

Cas:5394-63-8

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 5394-63-8 with competitive price

Cas:5394-63-8

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages ♦ High purity, all above 98.5%, no impurities after dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available ♦ W

2,2,6-Trimethyl-4H-1,3-dioxin-4-one CAS5394-63-8

Cas:5394-63-8

Min.Order:1 Kilogram

FOB Price: $7.0 / 9.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

4H-1,3-Dioxin-4-one,2,2,6-trimethyl- 5394-63-8

Cas:5394-63-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

2,2,6-Trimethyl-4H-1,3-dioxin-4-one CAS:5394-63-8 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high qualit

2,2,6-Trimethyl-4H-1,3-dioxin-4-one CAS:5394-63-8

Cas:5394-63-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

4H-1,3-Dioxin-4-one,2,2,6-trimethyl-

Cas:5394-63-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

4H-1,3-Dioxin-4-one,2,2,6-trimethyl-

Cas:5394-63-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Triumph International Development Limilted

Triumph has the complete production of G- KG - MT service chain,we can make the new technology into productivity quickly in the research and development of new products. Main Business Custom Synthesis: Trading(Raw Mater

2,2,6-Trimethyl-4H-1,3-dioxin-4-one

Cas:5394-63-8

Min.Order:0 Metric Ton

FOB Price: $18.0 / 20.0

Type:Lab/Research institutions

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures

2,2,6-Trimethyl-4H-1,3-dioxin-4-one

Cas:5394-63-8

Min.Order:1 Kilogram

FOB Price: $10.0 / 20.0

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

2,2,6-trimethyl-1,3-dioxine-4H-one

Cas:5394-63-8

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2,2,6-Trimethyl-4H-1,3-dioxin-4-one

Cas:5394-63-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

Featured products 2,2,6-Trimethyl-4H-1,3-dioxin-4-one

Cas:5394-63-8

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

2,2,6-Trimethyl-4H-1,3-dioxin-4-one

Cas:5394-63-8

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

2,2,6-Trimethyl-4H-1,3-dioxin-4-one

Cas:5394-63-8

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

2,2,6-Trimethyl-4H-1,3-dioxin-4-one

Cas:5394-63-8

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

2,2,6-Trimethyl-4H-1,3-dioxin-4-one Chemical Properties Melting point 12-13 °C(lit.) Boiling point ~275 °C(lit.) density 1.07 g/mL at 25 °C(lit.) refractive index n20/D 1.460(lit.) Fp 67 °F storage temp. 2-8&de

2,2,6-Trimethyl-4H-1,3-dioxin-4-one

Cas:5394-63-8

Min.Order:1 Gram

FOB Price: $66.0

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

2,2,6-Trimethyl-4H-1,3-dioxin-4-one CAS NO.5394-63-8

Cas:5394-63-8

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

2,2,6-Trimethyl-4H-1,3-dioxin-4-one

Cas:5394-63-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

2,2,6-Trimethyl-4H-1,3-dioxin-4-one CAS NO.5394-63-8

Cas:5394-63-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

2,2,6-Trimethyl-4H-1,3-dioxin-4-one CAS NO.5394-63-8

Cas:5394-63-8

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

2,2,6-Trimethyl-4H-1,3-dioxin-4-one

Cas:5394-63-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

2,2,6-trimethyl-1,3-dioxine-4H-one

Cas:5394-63-8

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Hebei Mojin Biotechnology Co.,Ltd

We produce carbomer by our own factory,carbomer 940 is our best seller.It is used for cosmetic and medical.And we also become agent for lubrizol.Our carbomer 940 get high viscosity and good transparency.The price will depond on the market,surely supp

4H-1,3-Dioxin-4-one,2,2,6-trimethyl-

Cas:5394-63-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

2,2,6-Trimethyl-4H-1,3-dioxin-4-one cas no. 5394-63-8 98%

Cas:5394-63-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

2,2,6-Trimethyl-1,3-dioxin-4-one

Cas:5394-63-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

2,2,6-trimethyl-4H-1,3-dioxin-4-one

Cas:5394-63-8

Min.Order:0

Negotiable

Type:Other

inquiry

Synthetic route

tert-butyl acetoacetate
1694-31-1

tert-butyl acetoacetate

2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

Conditions
ConditionsYield
With sulfuric acid; acetic anhydride In acetone at 0 - 20℃; for 5h;100%
tert-butyl acetoacetate
1694-31-1

tert-butyl acetoacetate

acetone
67-64-1

acetone

2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

Conditions
ConditionsYield
With sulfuric acid; acetic anhydride at 0 - 20℃; for 5h;98%
4-methyleneoxetan-2-one
674-82-8

4-methyleneoxetan-2-one

acetone
67-64-1

acetone

2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

Conditions
ConditionsYield
With Aliquat 336 In toluene at 70℃; for 6h;95%
toluene-4-sulfonic acid
acetylketene
691-45-2

acetylketene

acetone
67-64-1

acetone

2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

Conditions
ConditionsYield
83%
5-(1-hydroxyethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione
85920-63-4

5-(1-hydroxyethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione

2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

Conditions
ConditionsYield
In acetone; toluene at 111℃; for 2h;80%
4-methyleneoxetan-2-one
674-82-8

4-methyleneoxetan-2-one

toluene-4-sulfonic acid
104-15-4

toluene-4-sulfonic acid

acetone
67-64-1

acetone

2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

4-methyleneoxetan-2-one
674-82-8

4-methyleneoxetan-2-one

2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

Conditions
ConditionsYield
With pyridine; acetone; zinc(II) sulfate
With toluene-4-sulfonic acid; acetone
Ketene
463-51-4

Ketene

2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

Conditions
ConditionsYield
With diethyl ether; acetone; zinc(II) chloride
isopropenyl acetoacetate
93304-66-6

isopropenyl acetoacetate

2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

Conditions
ConditionsYield
With toluene-4-sulfonic acid In (2)H8-toluene at 70 - 90℃; for 1h;
With acetone In xylene at 91.7℃; for 1h;100 % Chromat.
isopropenyl acetoacetate
93304-66-6

isopropenyl acetoacetate

A

2,6-dimethylpyrone
1004-36-0

2,6-dimethylpyrone

B

3-acetyl-4-hydroxy-6-methyl-2H-pyran-2-one
771-03-9

3-acetyl-4-hydroxy-6-methyl-2H-pyran-2-one

C

2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

D

4-methyl-1,5-dioxaspiro[5.5]undec-3-en-2-one
4412-03-7

4-methyl-1,5-dioxaspiro[5.5]undec-3-en-2-one

E

1,3-diacetyl acetone
626-53-9

1,3-diacetyl acetone

Conditions
ConditionsYield
In xylene at 91.7℃; for 0.75h; Product distribution;A n/a
B n/a
C 15 % Chromat.
D 14 % Chromat.
E n/a
2,2,6-trimethyl-4H-1,3-dioxin-4-one
42490-66-4

2,2,6-trimethyl-4H-1,3-dioxin-4-one

A

2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

B

5-bromo-2,2,6-trimethyl-1,3-diox-5-in-4-one
104687-80-1

5-bromo-2,2,6-trimethyl-1,3-diox-5-in-4-one

Conditions
ConditionsYield
With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); potassium carbonate 1) -78 deg C, 2) -78 to 0 deg C, 2) 0 deg C; Yield given. Multistep reaction. Yields of byproduct given;
2-methyl-5-norbornen-2-yl exo-acetoacetate
93304-64-4

2-methyl-5-norbornen-2-yl exo-acetoacetate

2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 48 percent / 600 °C / 0.1 - 1 Torr
2: p-TsOH / toluene-d8 / 1 h / 70 - 90 °C
View Scheme
2-methyl-5-norbornen-2-yl endo-acetoacetate
93304-65-5

2-methyl-5-norbornen-2-yl endo-acetoacetate

2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 48 percent / 600 °C / 0.1 - 1 Torr
2: p-TsOH / toluene-d8 / 1 h / 70 - 90 °C
View Scheme
cycl-isopropylidene malonate
2033-24-1

cycl-isopropylidene malonate

2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: pyridine / dichloromethane / 2 h / 0 - 20 °C
2: acetone; toluene / 2 h / 111 °C
View Scheme
2-methyl-but-2-ene
513-35-9

2-methyl-but-2-ene

2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

(1S,6R)-1,3,3,7,7,8-Hexamethyl-2,4-dioxa-bicyclo[4.2.0]octan-5-one

(1S,6R)-1,3,3,7,7,8-Hexamethyl-2,4-dioxa-bicyclo[4.2.0]octan-5-one

Conditions
ConditionsYield
In hexane for 24h; Irradiation;100%
2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

(R,S)-2,2-dimethyl-1,3-dioxolane-4-methanol
100-79-8

(R,S)-2,2-dimethyl-1,3-dioxolane-4-methanol

(2,2-dimethyl-1,3-dioxolan-4-yl)methyl 3-oxobutanoate
85513-98-0

(2,2-dimethyl-1,3-dioxolan-4-yl)methyl 3-oxobutanoate

Conditions
ConditionsYield
In toluene at 20 - 130℃; for 3.5h; Inert atmosphere;100%
In xylene for 1h; Heating;
pyrrolidine
123-75-1

pyrrolidine

2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

1-(pyrrolidin-1-yl)butane-1,3-dione
41153-96-2

1-(pyrrolidin-1-yl)butane-1,3-dione

Conditions
ConditionsYield
In toluene at 20℃; for 12.25h; Reflux;100%
for 0.0333333h; microwave irradiation;87%
In toluene for 3h; Reflux;
In toluene for 3h; Reflux;
N-benzyloxyglycine ethyl ester
70771-89-0

N-benzyloxyglycine ethyl ester

2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

acetoacetamido-N-benzyloxyglycine ethyl ester
136942-58-0

acetoacetamido-N-benzyloxyglycine ethyl ester

Conditions
ConditionsYield
In toluene at 110℃; for 4h;100%
piperidine
110-89-4

piperidine

2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

1-(piperidin-1-yl)-butane-1,3-dione
1128-87-6

1-(piperidin-1-yl)-butane-1,3-dione

Conditions
ConditionsYield
In toluene at 20℃; for 12.25h; Reflux;100%
With sodium acetate In tetrahydrofuran for 24h; Reflux;99%
In 5,5-dimethyl-1,3-cyclohexadiene at 150℃; for 0.5h;95%
In toluene for 2h; Reflux; Inert atmosphere;93%
In toluene for 2h; Inert atmosphere; Reflux;93%
2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

N,N-diethylethylenediamine
100-36-7

N,N-diethylethylenediamine

N-(2-(diethylamino)ethyl)-3-oxobutanamide
590424-03-6

N-(2-(diethylamino)ethyl)-3-oxobutanamide

Conditions
ConditionsYield
at 130℃; for 0.0833333h; Microwave irradiation; Green chemistry;100%
at 110 - 115℃; Product distribution / selectivity;
3-Hydroxy-3-methyl-2-butanone
115-22-0

3-Hydroxy-3-methyl-2-butanone

2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

3-Acetyl-4,5,5-trimethyl-Δ3-butenolide
13156-10-0

3-Acetyl-4,5,5-trimethyl-Δ3-butenolide

Conditions
ConditionsYield
With triethylamine In toluene at 110℃; for 3h; Reagent/catalyst; Concentration; Molecular sieve; Inert atmosphere;100%
With triethylamine In toluene for 3h; Reflux;86%
With triethylamine for 3h; Reflux;
2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

ethylenediamine
107-15-3

ethylenediamine

7-methyl-3,4-dihydro-1H-1,4-diazepin-5(2H)-one
89600-61-3

7-methyl-3,4-dihydro-1H-1,4-diazepin-5(2H)-one

Conditions
ConditionsYield
at 130℃; for 0.0833333h; Microwave irradiation; Green chemistry;100%
2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

1,4-diaminobutane
110-60-1

1,4-diaminobutane

(Z)-4-methyl-6,7,8,9-tetrahydro-1H-1,5-diazonin-2(5H)-one

(Z)-4-methyl-6,7,8,9-tetrahydro-1H-1,5-diazonin-2(5H)-one

Conditions
ConditionsYield
at 130℃; for 0.0833333h; Microwave irradiation; Green chemistry;100%
2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

1,2-diamino-benzene
95-54-5

1,2-diamino-benzene

4-methyl-1H-benzo[b][1,4]diazepin-2(5H)-one
60568-46-9

4-methyl-1H-benzo[b][1,4]diazepin-2(5H)-one

Conditions
ConditionsYield
at 130℃; for 0.0833333h; Microwave irradiation; Green chemistry;100%
2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

L-Tryptophan
73-22-3

L-Tryptophan

(3-oxobutanoyl)-L-tryptophan

(3-oxobutanoyl)-L-tryptophan

Conditions
ConditionsYield
With potassium carbonate In water for 2h; Reflux;100%
L-leucine
61-90-5

L-leucine

2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

(3-oxobutanoyl)-L-leucine
1803-64-1

(3-oxobutanoyl)-L-leucine

Conditions
ConditionsYield
With potassium carbonate In water for 2h; Reflux;100%
2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

L-tryptophan methyl ester
4299-70-1

L-tryptophan methyl ester

methyl (3-oxobutanoyl)-L-tryptophanate

methyl (3-oxobutanoyl)-L-tryptophanate

Conditions
ConditionsYield
With potassium carbonate In water for 2h; Reflux;100%
Benzophenone-3
131-57-7

Benzophenone-3

2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

3-acetyl-7-methoxy-4-phenylcoumarin
93655-48-2

3-acetyl-7-methoxy-4-phenylcoumarin

Conditions
ConditionsYield
In decalin for 12h; Solvent; Reflux;100%
2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

diphenylamine
122-39-4

diphenylamine

N,N-diphenylacetoacetamide
2540-31-0

N,N-diphenylacetoacetamide

Conditions
ConditionsYield
In toluene at 20℃; for 12.25h; Reflux;100%
2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

1,2:5,6-di-O-isopropylidene-α-D-glucofuranose
582-52-5

1,2:5,6-di-O-isopropylidene-α-D-glucofuranose

3-Oxo-butyric acid (5R,6S)-5-(2,2-dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl ester
66888-11-7

3-Oxo-butyric acid (5R,6S)-5-(2,2-dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl ester

Conditions
ConditionsYield
In xylene at 150℃; for 0.5h;99%
2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

(-)-8-phenylmenthol
65253-04-5

(-)-8-phenylmenthol

(+)-(1R,2S,5R)-8-phenylmenthyl 3-oxobutanoate
90358-31-9

(+)-(1R,2S,5R)-8-phenylmenthyl 3-oxobutanoate

Conditions
ConditionsYield
With sodium acetate In tetrahydrofuran for 24h; Reflux;99%
In xylene at 160℃; for 0.5h; preheated bath;
2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

(2S,3S,4R,5S,6R)-3,4,5-Tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-ol
96553-53-6

(2S,3S,4R,5S,6R)-3,4,5-Tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-ol

3-Oxo-butyric acid (2R,3S,4R,5S,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl ester
96453-23-5

3-Oxo-butyric acid (2R,3S,4R,5S,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl ester

Conditions
ConditionsYield
In xylene at 150℃; for 0.5h;99%
2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

cyclohexanol
108-93-0

cyclohexanol

cyclohexyl 3-oxobutanoate
6947-02-0

cyclohexyl 3-oxobutanoate

Conditions
ConditionsYield
With sodium acetate In tetrahydrofuran for 24h; Reflux;99%
In xylene for 0.5h; Heating;80%
In 5,5-dimethyl-1,3-cyclohexadiene at 150℃; for 2h;76%
Esterification;35%
Condensation;
2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

tert-butyl alcohol
75-65-0

tert-butyl alcohol

tert-butyl acetoacetate
1694-31-1

tert-butyl acetoacetate

Conditions
ConditionsYield
With sodium acetate In tetrahydrofuran for 24h; Reflux;99%
Esterification;92%
for 0.1h; microwave irradiation;70%
2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

N-tert-butylbenzylamine
3378-72-1

N-tert-butylbenzylamine

N-tert-butyl-N-benzylacetoacetamide
151813-55-7

N-tert-butyl-N-benzylacetoacetamide

Conditions
ConditionsYield
In 5,5-dimethyl-1,3-cyclohexadiene at 120℃; for 5h; Dean-Stark; Inert atmosphere;99%
In m-xylene at 120 - 150℃;
2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

(+/-)-1-(N-tert-Butoxycarbonylamino)propan-2-one
170384-29-9

(+/-)-1-(N-tert-Butoxycarbonylamino)propan-2-one

C12H19NO5

C12H19NO5

Conditions
ConditionsYield
In 5,5-dimethyl-1,3-cyclohexadiene at 150℃; for 0.166667h; Inert atmosphere;99%
(R,E)-7-hydroxy-7-methyl-3-(prop-1-en-1-yl)-6H-isochromene-6,8(7H)-dione
915789-19-4

(R,E)-7-hydroxy-7-methyl-3-(prop-1-en-1-yl)-6H-isochromene-6,8(7H)-dione

2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

(S)-trichoflectin

(S)-trichoflectin

Conditions
ConditionsYield
With triethylamine In toluene at 110℃; for 1h; Molecular sieve; Inert atmosphere; Schlenk technique;99%
2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

(S,E)-7-hydroxy-7-methyl-3-(prop-1-en-1-yl)-6H-isochromene-6,8(7H)-dione

(S,E)-7-hydroxy-7-methyl-3-(prop-1-en-1-yl)-6H-isochromene-6,8(7H)-dione

(R)-trichoflectin

(R)-trichoflectin

Conditions
ConditionsYield
With triethylamine In toluene at 110℃; for 1h; Molecular sieve; Inert atmosphere; Schlenk technique;99%
6-chloro-1,2,3,4-tetrahydroquinoline
49716-18-9

6-chloro-1,2,3,4-tetrahydroquinoline

2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

C13H14ClNO2

C13H14ClNO2

Conditions
ConditionsYield
In toluene at 110℃; for 1.5h; Microwave irradiation;99%
alpha-D-glucopyranose
492-62-6

alpha-D-glucopyranose

2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

D-(+)-glucose pentaacetoacetate
96481-26-4

D-(+)-glucose pentaacetoacetate

Conditions
ConditionsYield
In xylene at 150℃; for 0.5h;98.5%
2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

3-Hydroxypropionitrile
109-78-4

3-Hydroxypropionitrile

2-cyanoethylacetoacetate
65193-87-5

2-cyanoethylacetoacetate

Conditions
ConditionsYield
In o-xylene at 141℃; for 2h;98.3%
In 5,5-dimethyl-1,3-cyclohexadiene at 140 - 145℃; for 1h;90%
In xylene at 140 - 145℃; for 1h;81.6%
dimethyl (S)-malate
617-55-0

dimethyl (S)-malate

2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

(1'S)-1',2'-bis(methoxycarbonyl)ethyl 3-oxobutanoate
50595-57-8

(1'S)-1',2'-bis(methoxycarbonyl)ethyl 3-oxobutanoate

Conditions
ConditionsYield
In toluene for 1h; Heating;98%
2,2,6-trimethyl-4H-1,3-dioxin-4-one
5394-63-8

2,2,6-trimethyl-4H-1,3-dioxin-4-one

aniline
62-53-3

aniline

N-phenylacetoacetamide
102-01-2

N-phenylacetoacetamide

Conditions
ConditionsYield
With sodium acetate In tetrahydrofuran for 24h; Reflux;98%
In water for 2.5h; Reflux; Green chemistry;94%
In 5,5-dimethyl-1,3-cyclohexadiene Reflux;82%

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