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HANGZHOU TIANYE CHEMICALS CO., LTD.

Product:4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane Assay:98% min Water:0.5%max Appearance: Colorless to yellow transparent liquid CAS:57280-22-5 MF:C7H12O3 MW:144.17 EINECS:421-750-9 MDL No.:MFCD16621162 Properties Boiling point:179℃

4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane

Cas:57280-22-5

Min.Order:1 Gram

Negotiable

Type:Trading Company

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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

4,4-Dimethyl-3,5,8-trioxabicyclo[5.1.0]octane Manufacturer/High quality/Best price/In stock

Cas:57280-22-5

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Jinan Finer Chemical Co., Ltd

Product Description Product website: http://www.finerchem.com Product Name 4,4-Dimethyl-3,5,8-trioxabicyclo[5.1.0]octane

4,4-Dimethyl-3,5,8-trioxabicyclo[5.1.0]octane

Cas:57280-22-5

Min.Order:1 Gram

FOB Price: $8.0

Type:Lab/Research institutions

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

3,5,8-Trioxabicyclo[5.1.0]octane, 4,4-diMethyl-

Cas:57280-22-5

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]octane

Cas:57280-22-5

Min.Order:1

Negotiable

Type:Other

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Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality 4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane

Cas:57280-22-5

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

4,4-Dimethyl-3,5,8-trioxabicyclo[5.1.0]octane

Cas:57280-22-5

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

4,4-Dimethyl-3,5,8-trioxabicyclo[5.1.0]octane

Cas:57280-22-5

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

GIHI CHEMICALS CO.,LIMITED

GIHI CHEMICALS exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, GIHI CHEMICALS is your best choice. pls contact with us freely for getting detailed produc

China biggest manufacturer 4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane 57280-22-5

Cas:57280-22-5

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company engages in Sodium Tripolyphosphate (STPP) and Sodium Hexametabphosphate (SHMP) production; development of noble metal catalysts, synthesis of electronic chemical materials and general chemicals Imp&Exp trading business. The company

TIANFU-CHEM - 4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane

Cas:57280-22-5

Min.Order:1 Kilogram

FOB Price: $1000.0

Type:Lab/Research institutions

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane / LIDE PHARMA- Factory supply / Best price

Cas:57280-22-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 57280-22-5 with competitive price

Cas:57280-22-5

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Agrochemical Intermediates, 4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane CAS:57280-22-5

Cas:57280-22-5

Min.Order:1 Kilogram

FOB Price: $15.4 / 16.8

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane CAS:57280-22-5 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing i

4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane CAS:57280-22-5

Cas:57280-22-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane

Cas:57280-22-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane

Cas:57280-22-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

4,4-Dimethyl-3,5,8-Trioxabicyclo[5.1.0]octane

Cas:57280-22-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We have s

4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane

Cas:57280-22-5

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

CAS 57280-22-5 4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane

Cas:57280-22-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane

Cas:57280-22-5

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

4,4-DIMETHYL-3,5,8-TRIOXABICYCLO[5.1.0]OCTANE

Cas:57280-22-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]octane(EP2)

Cas:57280-22-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]octane

Cas:57280-22-5

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and als

4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane

Cas:57280-22-5

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

3,5,8-Trioxabicyclo[5.1.0]octane, 4,4-diMethyl- CAS NO.57280-22-5

Cas:57280-22-5

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane

Cas:57280-22-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: 4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane Synonyms: 4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane;3,5,8-Trioxabicyclo[5.1.0]octane, 4,4-diMethyl-;4,4-diMethyl-3,5,8-trioxabicyclo[5.1.0]octane(EP2);4,4-Dimethyl-3,5,8-trioxabi

4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane

Cas:57280-22-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane

Cas:57280-22-5

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Siwei Development Group Ltd.

Product name: 4,4-Dimethyl-3,5,8-Trioxabicyclo[5.1.0]octane CAS No.: 57280-22-5 Molecule Formula:C7H12O3 Molecule Weight:144.17 Purity: 99.0% Package: 25kg/drum Description:White or off-white powder Manufacture Standards:Enterprise St

Lower Price 4,4-Dimethyl-3,5,8-Trioxabicyclo[5.1.0]octane

Cas:57280-22-5

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

4,4-Dimethyl-3,5,8-trioxabic-yclo[5,1,0]Octane

Cas:57280-22-5

Min.Order:0

Negotiable

Type:Trading Company

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Synthetic route

2,2-dimethyl-4,7-dihydro-1,3-dioxepin
1003-83-4

2,2-dimethyl-4,7-dihydro-1,3-dioxepin

4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane
57280-22-5

4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane

Conditions
ConditionsYield
With disodium hydrogenphosphate; dihydrogen peroxide; sodium hydroxide In methanol; water; acetonitrile at 60 - 80℃; pH=7 - 9.5; Large scale; Green chemistry;85.2%
With disodium hydrogenphosphate; 3-chloro-benzenecarboperoxoic acid In dichloromethane at 20℃; for 18h; Inert atmosphere;85%
With disodium hydrogenphosphate; dihydrogen peroxide; Hexafluoroacetone In 1,2-dichloro-ethane for 24h; Heating;83%
2,2-dimethoxy-propane
77-76-9

2,2-dimethoxy-propane

4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane
57280-22-5

4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: toluene-4-sulfonic acid / dichloromethane / 3 h / 20 °C / Inert atmosphere
2: 3-chloro-benzenecarboperoxoic acid; disodium hydrogenphosphate / dichloromethane / 18 h / 20 °C / Inert atmosphere
View Scheme
C7H13BrO3

C7H13BrO3

4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane
57280-22-5

4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane

Conditions
ConditionsYield
With potassium carbonate In methanol at 20℃; for 16h;19 g
4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane
57280-22-5

4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane

Trimethylenediamine
109-76-2

Trimethylenediamine

C17H34N2O6

C17H34N2O6

Conditions
ConditionsYield
In ethanol epoxide:amine=2:1;100%
4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane
57280-22-5

4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane

benzylamine
100-46-9

benzylamine

trans-6-benzylamino-2,2'-dimethyl-1,3-dioxocycloheptan-5-ol
1036765-71-5

trans-6-benzylamino-2,2'-dimethyl-1,3-dioxocycloheptan-5-ol

Conditions
ConditionsYield
Stage #1: benzylamine With titanium(IV) isopropylate; (R)-1,1'-Bi-2-naphthol; (R)-6,6'-dibromo-1,1'-binaphth-2-ol In toluene at 20℃; for 0.5h;
Stage #2: 4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane With water In toluene at 40℃; for 12h; optical yield given as %ee;
99%
With titanium(IV) isopropylate; (R)-1,1'-Bi-2-naphthol In toluene enantioselective reaction;78%
4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane
57280-22-5

4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane

benzylamine
100-46-9

benzylamine

(5R,6S)-6-(benzylamino)-2,2-dimethyl-1,3-dioxepan-5-ol

(5R,6S)-6-(benzylamino)-2,2-dimethyl-1,3-dioxepan-5-ol

Conditions
ConditionsYield
With C92H72N2O6*2Ti*2O In water; toluene at 40℃; for 18h; Reagent/catalyst; Inert atmosphere; Green chemistry;99%
Stage #1: benzylamine With titanium(IV) isopropylate; C20H24O2; (R)-3,3'-diiodo-2,2'-dihydroxy-1,1'-binaphthyl In toluene at 20℃; for 0.5h;
Stage #2: 4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane With water In toluene at 40℃; for 12h; optical yield given as %ee;
27%
4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane
57280-22-5

4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane

1,4,7-tris-tert-butoxycarbonylmethyl-1,4,7,10-tetraazacyclododecane
122555-91-3

1,4,7-tris-tert-butoxycarbonylmethyl-1,4,7,10-tetraazacyclododecane

1,4,7-tris(tert-butoxycarbonylmethyl)10-(6-hydroxy-2,2-dimethyl-1,3-dioxepane-5yl)-1,4,7,10-tetraazacyclododecane

1,4,7-tris(tert-butoxycarbonylmethyl)10-(6-hydroxy-2,2-dimethyl-1,3-dioxepane-5yl)-1,4,7,10-tetraazacyclododecane

Conditions
ConditionsYield
With potassium carbonate In isopropyl alcohol at 60℃; for 12h; Reagent/catalyst; Temperature;99%
4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane
57280-22-5

4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane

ethylenediamine
107-15-3

ethylenediamine

6-(2-Amino-ethylamino)-2,2-dimethyl-[1,3]dioxepan-5-ol

6-(2-Amino-ethylamino)-2,2-dimethyl-[1,3]dioxepan-5-ol

Conditions
ConditionsYield
In ethanol epoxide:amine=1:1; addition of epoxide to amine dropwise over 1 h;98%
4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane
57280-22-5

4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane

thiophenol
108-98-5

thiophenol

(2R*,3R*)-1,4-di-O-isopropylidene-3-phenylthio-1,2,4-butanetriol

(2R*,3R*)-1,4-di-O-isopropylidene-3-phenylthio-1,2,4-butanetriol

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran 0 deg C, 30 min, reflux, 1 h;96.9%
bis(3-aminopropyl)amine
56-18-8

bis(3-aminopropyl)amine

4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane
57280-22-5

4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane

6-[3-(3-Amino-propylamino)-propylamino]-2,2-dimethyl-[1,3]dioxepan-5-ol

6-[3-(3-Amino-propylamino)-propylamino]-2,2-dimethyl-[1,3]dioxepan-5-ol

Conditions
ConditionsYield
In ethanol epoxide:amine=1:1; addition of epoxide to amine dropwise over 1 h;92%
4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane
57280-22-5

4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane

isopropylamine
75-31-0

isopropylamine

6-(isopropylamino)-2,2-dimethyl-1,3-dioxepan-5-ol
1036765-73-7

6-(isopropylamino)-2,2-dimethyl-1,3-dioxepan-5-ol

Conditions
ConditionsYield
Stage #1: isopropylamine With titanium(IV) isopropylate; (R)-1,1'-Bi-2-naphthol In toluene at 20℃;
Stage #2: 4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane With water In toluene at 40℃; for 12h; optical yield given as %ee;
91%
4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane
57280-22-5

4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane

(5S,6S)-6-Iodo-2,2-dimethyl-[1,3]dioxepan-5-ol

(5S,6S)-6-Iodo-2,2-dimethyl-[1,3]dioxepan-5-ol

Conditions
ConditionsYield
With lithium iodide for 15h; Ambient temperature;90%
With silica gel; lithium iodide for 0.25h; Ambient temperature;90%
4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane
57280-22-5

4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane

trans-2,2-Dimethyl-6-hydroxy-5-amino-1,3-dioxepane
188923-20-8

trans-2,2-Dimethyl-6-hydroxy-5-amino-1,3-dioxepane

Conditions
ConditionsYield
With ammonia In water87%
4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane
57280-22-5

4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane

tert-butylamine
75-64-9

tert-butylamine

6-(tert-butylamino)-2,2-dimethyl-1,3-dioxepan-5-ol
1036765-74-8

6-(tert-butylamino)-2,2-dimethyl-1,3-dioxepan-5-ol

Conditions
ConditionsYield
Stage #1: tert-butylamine With titanium(IV) isopropylate; (R)-1,1'-Bi-2-naphthol In toluene at 20℃;
Stage #2: 4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane With water In toluene at 40℃; for 48h; optical yield given as %ee;
85%
4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane
57280-22-5

4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane

1,4,7-tris(tert-butyloxycarbonyl)-1,4,7,10-tetraazacyclododecane
175854-39-4

1,4,7-tris(tert-butyloxycarbonyl)-1,4,7,10-tetraazacyclododecane

C12H28N4O3

C12H28N4O3

Conditions
ConditionsYield
Stage #1: 4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane; 1,4,7-tris(tert-butyloxycarbonyl)-1,4,7,10-tetraazacyclododecane With lithium chloride In isopropyl alcohol for 20h; Reflux;
Stage #2: With hydrogenchloride In water; isopropyl alcohol at 60℃; for 2h;
85%
bromobenzene
108-86-1

bromobenzene

4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane
57280-22-5

4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane

(5S,6R)-2,2-dimethyl-6-phenyl-1,3-dioxepan-5-ol

(5S,6R)-2,2-dimethyl-6-phenyl-1,3-dioxepan-5-ol

Conditions
ConditionsYield
With [2,2]bipyridinyl; manganese; (1,2-dimethoxyethane)dichloronickel(II); bis(η5((1R,2S,5R)-5-methyl-2-[prop-2-yl]-cyclohex-1-yl)cyclopentadienyl)-titanium dichloride; triethylamine hydrochloride at 20℃; for 12h; Inert atmosphere; Glovebox; Autoclave; enantioselective reaction;82%
4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane
57280-22-5

4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane

(5S,6S)-6-Bromo-2,2-dimethyl-[1,3]dioxepan-5-ol

(5S,6S)-6-Bromo-2,2-dimethyl-[1,3]dioxepan-5-ol

Conditions
ConditionsYield
With lithium bromide for 8h; Ambient temperature;80%
With silica gel; lithium bromide for 8h; Ambient temperature;80%
1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid trisodium salt

1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid trisodium salt

4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane
57280-22-5

4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane

2,2',2"-(10-(1,3,4-trihydroxybutan-2-yl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetic acid
138168-36-2

2,2',2"-(10-(1,3,4-trihydroxybutan-2-yl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetic acid

Conditions
ConditionsYield
Stage #1: 1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid trisodium salt; 4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane In isopropyl alcohol for 10h; Inert atmosphere; Reflux; Industrial scale;
Stage #2: With hydrogenchloride In water for 1h; Solvent; Industrial scale;
80%
1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid trisodium salt

1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid trisodium salt

gadolinium(III) chloride

gadolinium(III) chloride

4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane
57280-22-5

4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane

gadolinium complex of 10-[2,3-dihydroxy-1-(hydroxymethyl)propyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid

gadolinium complex of 10-[2,3-dihydroxy-1-(hydroxymethyl)propyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid

Conditions
ConditionsYield
Stage #1: 1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid trisodium salt; 4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane With hydrogenchloride In water at 40 - 80℃; for 12h;
Stage #2: gadolinium(III) chloride In water at 50℃; for 1h;
Stage #3: With hydrogenchloride; sodium hydroxide more than 3 stages;
79.1%
4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane
57280-22-5

4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane

lithium cyanide
2408-36-8

lithium cyanide

(+/-)-trans-6-hydroxy-2,2-dimethyl-1,3-dioxepane-5-carbonitrile
141077-78-3

(+/-)-trans-6-hydroxy-2,2-dimethyl-1,3-dioxepane-5-carbonitrile

Conditions
ConditionsYield
In tetrahydrofuran for 3h; Heating;79%
4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane
57280-22-5

4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane

trimethylsilan
993-07-7

trimethylsilan

carbon monoxide
201230-82-2

carbon monoxide

2,2-Dimethyl-5-trimethylsilanyloxy-6-trimethylsilanyloxymethyl-[1,3]dioxepane

2,2-Dimethyl-5-trimethylsilanyloxy-6-trimethylsilanyloxymethyl-[1,3]dioxepane

Conditions
ConditionsYield
dicobalt octacarbonyl In toluene at 25℃; under 760 Torr; for 20h;77%
4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane
57280-22-5

4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane

(5S,6S)-6-Chloro-2,2-dimethyl-[1,3]dioxepan-5-ol

(5S,6S)-6-Chloro-2,2-dimethyl-[1,3]dioxepan-5-ol

Conditions
ConditionsYield
With water; silica gel; lithium chloride for 96h; Ambient temperature;76%
4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane
57280-22-5

4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane

1,4,7,10-tetraazacyclododecan
294-90-6

1,4,7,10-tetraazacyclododecan

3-(1,4,7,10-tetraazacyclododecane-1-yl)butane-1,2,4-triol tetrahydrochloride

3-(1,4,7,10-tetraazacyclododecane-1-yl)butane-1,2,4-triol tetrahydrochloride

Conditions
ConditionsYield
Stage #1: 4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane; 1,4,7,10-tetraazacyclododecan With lithium chloride In isopropyl alcohol at 85 - 95℃; Large scale;
Stage #2: With hydrogenchloride In methanol for 3h; Reflux; Large scale;
73.4%
4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane
57280-22-5

4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane

4,4-dimethyl-3,5-dioxacycloheptanol
141509-49-1

4,4-dimethyl-3,5-dioxacycloheptanol

Conditions
ConditionsYield
With lithium aluminium tetrahydride In diethyl ether for 24h; Ambient temperature;68%
4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane
57280-22-5

4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane

1,5-diamino-3-azapentane
111-40-0

1,5-diamino-3-azapentane

6-[2-(2-Amino-ethylamino)-ethylamino]-2,2-dimethyl-[1,3]dioxepan-5-ol

6-[2-(2-Amino-ethylamino)-ethylamino]-2,2-dimethyl-[1,3]dioxepan-5-ol

Conditions
ConditionsYield
In ethanol epoxide:amine=1:1; addition of epoxide to amine dropwise over 1 h;67%

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