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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

2-Methylthio-4-pyrimidinol Manufacturer/High quality/Best price/In stock

Cas:5751-20-2

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

he company has advanced technology, as well as a large number of excellent R & D team, to provide customers from the grams to one hundred kilograms and tons of high-quality products, competitive prices and quality se T rvice Appearance:

2-Methylthio-4-pyriMidinol

Cas:5751-20-2

Min.Order:1 Gram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 2-Methylthiopyrimidin-4-Ol

Cas:5751-20-2

Min.Order:1

Negotiable

Type:Other

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2-(Methylthio)-1H-pyrimidin-4-one

Cas:5751-20-2

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

2-Methylthio-4-pyrimidinol

Cas:5751-20-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 5751-20-2 with best quality

Cas:5751-20-2

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Hot Sell Factory Supply Raw Material CAS5751-20-2 2-Methylthio-4-pyrimidinol

Cas:5751-20-2

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:powder Storage:Store in sealed containers at cool & dry pla

Top quality 2-Methylthio-4-pyrimidinol with CAS: 5751-20-2

Cas:5751-20-2

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

4(3H)-Pyrimidinone,2-(methylthio)- 5751-20-2

Cas:5751-20-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Pharmaceutical Intermediate, 2-Methylthio-4-pyrimidinol CAS:5751-20-2

Cas:5751-20-2

Min.Order:1 Kilogram

FOB Price: $42.7 / 48.3

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

2-Methylthio-4-pyrimidinol CAS:5751-20-2 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic

2-Methylthio-4-pyrimidinol CAS:5751-20-2

Cas:5751-20-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2-Methylthio-4-pyrimidinol

Cas:5751-20-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Product Detail Minimum Order Qty. 10 Gram Supply Ability 500 Kilograms/Month Storage store in cool, dry, ventilated place 20℃ Delivery Time 3 business days after payment Payment Term TT,western union,Paypal,

2-Methylsulfanyl-3H-pyrimidin-4-one CAS NO.: 5751-20-2

Cas:5751-20-2

Min.Order:20 Metric Ton

Negotiable

Type:Trading Company

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

4(3H)-Pyrimidinone,2-(methylthio)-

Cas:5751-20-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

2-(Methylthio)-1H-Pyrimidin-4-One

Cas:5751-20-2

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

HANWAYS CHEMPHARM CO.,LIMITED

We are concentrating on APIs and pharmaceutical intermediates. With in depth knowledge and understanding in this industry, we are indulged in supplying a wide assortments of 2-Methylthio-4-pyrimidinol from Wuhan, Hubei, China. It is made obta

2-Methylthio-4-pyrimidinol

Cas:5751-20-2

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Taizhou Crene Biotechnology co.ltd

Our company provides one-stop services of research - development - production for a variety of special prouducts. Not only do we make effective use of our strong technological strength, but also establish of cooperative relations with several well-

2-(Methylthio)pyrimidin-4(3H)-one 5751-20-2

Cas:5751-20-2

Min.Order:50 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

2-METHYLTHIO-4-PYRIMIDINOL

Cas:5751-20-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

2-(Methylthio)pyrimidin-4(3H)-one

Cas:5751-20-2

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

NewCan Biotech Limited

NewCan Biotech Limited was established in 2021 and is primarily engaged in the research, development, production, and sales of sugars, nucleosides, nucleotides, phosphorylated monomers, as well as next-generation antiviral and antitumor drug intermed

2-Methylthio-4-hydroxypyrimidine

Cas:5751-20-2

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2-Methylthio-4-pyrimidinol

Cas:5751-20-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

2-(methylsulfanyl)-3,4-dihydropyrimidin-4-one

Cas:5751-20-2

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 2-Methylthiopyrimidin-4-Ol

Cas:5751-20-2

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

2-Methylthio-4-pyrimidinolAppearance:Pls see the Details Storage:Keep away of light, hot, water, Store in dry, dark and ventilated place Package:according to customers' requirements Application:Steroids, Cosmetics Ingredients, APIs, Intermediates, OL

2-Methylthio-4-pyrimidinol

Cas:5751-20-2

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

CAS5751-20-2 2-Methylthio-4-pyrimidinol

Cas:5751-20-2

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white crystals powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:25kg/drum, or as per your request. Application:For medicine , pesticide i

2-Methylthio-4-pyrimidinol

Cas:5751-20-2

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Siwei Development Group Ltd.

Product name: 2-Methylthio-4-Pyrimidone CAS No.: 5751-20-2 Molecule Formula:C5H6N2OS Molecule Weight:142.18 Purity: 99.0% Package: 25kg/drum Description:White crystalline powder Manufacture Standards:Enterprise Standard TESTING I

Lower Price 2-Methylthio-4-Pyrimidone on stock

Cas:5751-20-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

2-(Methylsulfanyl)pyrimidin-4-ol ,98%

Cas:5751-20-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Think Chemical Co. Ltd

HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture. With about ten years of business experiences on the marketing & distribution, thinkchem specializes in exp

2-Methylthio-4-pyrimidinol

Cas:5751-20-2

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: 2-Methylthio-4-pyrimidinol Synonyms: 2-(Methylsulfanyl)pyrimidin-4-ol ,98%;2-METHYLSULFANYL-4-OXOPYRIMIDINE;2-methylthiopyrimidin-4-one;2-(Methylthio)pyrimidine-4(1H)-one;2-Methylthio-4(3H)-pyrimidone;(2R,3R,4S,5R)-2-amino-3,4,5,6

2-Methylthio-4-pyrimidinol

Cas:5751-20-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

2-thiouracil
141-90-2

2-thiouracil

methyl iodide
74-88-4

methyl iodide

2-Methylthiouracil
5751-20-2

2-Methylthiouracil

Conditions
ConditionsYield
Stage #1: 2-thiouracil; methyl iodide With sodium hydroxide In water at 20℃; for 16h;
Stage #2: With acetic acid In water
100%
Stage #1: 2-thiouracil With sodium hydroxide In water at 60 - 70℃;
Stage #2: methyl iodide In ethanol; water at 30 - 60℃; for 0.333333h;
Stage #3: With acetic acid In ethanol; water at 20℃;
100%
With sodium hydroxide at 20℃; for 18h;99%
n-propyl formylacetate

n-propyl formylacetate

carbamimidothioic acid methyl ester
2986-19-8

carbamimidothioic acid methyl ester

2-Methylthiouracil
5751-20-2

2-Methylthiouracil

Conditions
ConditionsYield
In isopropyl alcohol at 35℃;97%
methyl 3-oxopropionate
63857-17-0

methyl 3-oxopropionate

carbamimidothioic acid methyl ester
2986-19-8

carbamimidothioic acid methyl ester

2-Methylthiouracil
5751-20-2

2-Methylthiouracil

Conditions
ConditionsYield
In ethanol at 10℃;96%
3-oxo-propionic acid ethyl ester
34780-29-5

3-oxo-propionic acid ethyl ester

carbamimidothioic acid methyl ester
2986-19-8

carbamimidothioic acid methyl ester

2-Methylthiouracil
5751-20-2

2-Methylthiouracil

Conditions
ConditionsYield
In methanol at 5℃; for 3h;94.9%
isopropyl formylacetate
108350-20-5

isopropyl formylacetate

carbamimidothioic acid methyl ester
2986-19-8

carbamimidothioic acid methyl ester

2-Methylthiouracil
5751-20-2

2-Methylthiouracil

Conditions
ConditionsYield
In methanol at 25℃;93%
n-butyl formylacetate

n-butyl formylacetate

carbamimidothioic acid methyl ester
2986-19-8

carbamimidothioic acid methyl ester

2-Methylthiouracil
5751-20-2

2-Methylthiouracil

Conditions
ConditionsYield
In ethanol at 25℃;93%
isobutyl formylacetate

isobutyl formylacetate

carbamimidothioic acid methyl ester
2986-19-8

carbamimidothioic acid methyl ester

2-Methylthiouracil
5751-20-2

2-Methylthiouracil

Conditions
ConditionsYield
In ethanol at 25℃;93%
3-oxo-propionic acid tert-butyl ester
108350-21-6

3-oxo-propionic acid tert-butyl ester

carbamimidothioic acid methyl ester
2986-19-8

carbamimidothioic acid methyl ester

2-Methylthiouracil
5751-20-2

2-Methylthiouracil

Conditions
ConditionsYield
In ethanol at 25℃;93%
2-thiouracil
141-90-2

2-thiouracil

carbonic acid dimethyl ester
616-38-6

carbonic acid dimethyl ester

2-Methylthiouracil
5751-20-2

2-Methylthiouracil

Conditions
ConditionsYield
With tetrabutylammomium bromide; potassium carbonate at 120℃; for 8h;93%
With tetrabutylammomium bromide; potassium carbonate In N,N-dimethyl-formamide at 120℃; for 6h;92.6%
boron dimethyl-trifluoro sulphide
353-43-5

boron dimethyl-trifluoro sulphide

2-chloropyrimidin-4(3H)-one

2-chloropyrimidin-4(3H)-one

2-Methylthiouracil
5751-20-2

2-Methylthiouracil

Conditions
ConditionsYield
In neat (no solvent) at 60℃; for 16h; Sealed tube;83%
methyl iodide
74-88-4

methyl iodide

2-Methylthiouracil
5751-20-2

2-Methylthiouracil

Conditions
ConditionsYield
Stage #1: 2-thiouracil With sodium methylate In methanol at 20℃; for 0.0833333h;
Stage #2: methyl iodide In methanol
74%
Stage #1: 2-thiouracil With sodium hydroxide In water at 20℃; for 0.333333h;
Stage #2: methyl iodide In tetrahydrofuran; water at 20℃; for 18h; Product distribution / selectivity;
60%
Stage #1: 2-thiouracil With sodium hydroxide In water at 20℃; for 0.333333h;
Stage #2: methyl iodide In tetrahydrofuran; water at 20℃; for 18h; Product distribution / selectivity;
60%
4-(dimethylamino)-2-methylsulfanyl-1,3-diazabuta-1,3-dienium iodide
344361-86-0

4-(dimethylamino)-2-methylsulfanyl-1,3-diazabuta-1,3-dienium iodide

acetyl chloride
75-36-5

acetyl chloride

2-Methylthiouracil
5751-20-2

2-Methylthiouracil

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃; for 3h;68%
4-hydroxy-2-mercaptopyrimidine
141-90-2

4-hydroxy-2-mercaptopyrimidine

methyl iodide
74-88-4

methyl iodide

2-Methylthiouracil
5751-20-2

2-Methylthiouracil

Conditions
ConditionsYield
With sodium hydroxide In ethanol; water at 30 - 60℃; for 0.333333h;47%
Stage #1: 4-hydroxy-2-mercaptopyrimidine With sodium methylate In methanol at 20℃; for 0.0833333h;
Stage #2: methyl iodide In methanol
trimethyl phosphite
512-56-1

trimethyl phosphite

2-thiouracil
141-90-2

2-thiouracil

A

2-Methylthiouracil
5751-20-2

2-Methylthiouracil

B

2-methylthio-3-methylpyrimidin-4(3H)-one
6327-98-6

2-methylthio-3-methylpyrimidin-4(3H)-one

C

1-methyl-2-methysulfanylpyrimidin-4(1H)-one
6330-98-9

1-methyl-2-methysulfanylpyrimidin-4(1H)-one

D

4-methoxy-2-(methylthio)pyrimidine
76541-59-8

4-methoxy-2-(methylthio)pyrimidine

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide at 80℃; for 3h; Further byproducts given;A 13%
B 10%
C 35%
D 6%
trimethyl phosphite
512-56-1

trimethyl phosphite

2-thiouracil
141-90-2

2-thiouracil

A

2-Methylthiouracil
5751-20-2

2-Methylthiouracil

B

2-methylthio-3-methylpyrimidin-4(3H)-one
6327-98-6

2-methylthio-3-methylpyrimidin-4(3H)-one

C

1-methyl-2-methysulfanylpyrimidin-4(1H)-one
6330-98-9

1-methyl-2-methysulfanylpyrimidin-4(1H)-one

D

1,3-dimethyl-2-thiouracil
1194-71-4

1,3-dimethyl-2-thiouracil

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide at 80℃; for 3h; Further byproducts given;A 13%
B 10%
C 35%
D 8%
trimethyl phosphite
512-56-1

trimethyl phosphite

2-thiouracil
141-90-2

2-thiouracil

2-Methylthiouracil
5751-20-2

2-Methylthiouracil

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 80℃; for 55h;17%
2-(methylsulfanyl)pyrimidin-4-ol
5751-20-2

2-(methylsulfanyl)pyrimidin-4-ol

2-Methylthiouracil
5751-20-2

2-Methylthiouracil

Conditions
ConditionsYield
at 226.9℃; Equilibrium constant;
4-(N-benzylcarbamoylethoxy)-2-methylthiopyrimidine
109389-01-7

4-(N-benzylcarbamoylethoxy)-2-methylthiopyrimidine

A

2-Methylthiouracil
5751-20-2

2-Methylthiouracil

B

N-benzylacrylamide
13304-62-6

N-benzylacrylamide

Conditions
ConditionsYield
With sodium hydride; paraffin In tetrahydrofuran
sodium formylacetic acid ethyl ester

sodium formylacetic acid ethyl ester

hydriodide of S-methyl-isothiourea

hydriodide of S-methyl-isothiourea

2-Methylthiouracil
5751-20-2

2-Methylthiouracil

Conditions
ConditionsYield
With sodium hydroxide
2-Methylthiouracil
5751-20-2

2-Methylthiouracil

ethyl 4-(methylamino)piperidine-1-carboxylate
73733-69-4

ethyl 4-(methylamino)piperidine-1-carboxylate

2-[(1-carbethoxy-4-piperidinyl)(methyl)amino]-1H-pyrimidin-4-one

2-[(1-carbethoxy-4-piperidinyl)(methyl)amino]-1H-pyrimidin-4-one

Conditions
ConditionsYield
for 26h; Kinetics;99.4%
2-Methylthiouracil
5751-20-2

2-Methylthiouracil

phenylboronic acid
98-80-6

phenylboronic acid

2-(methylsulfanyl)-4-phenylpyrimidine
56734-10-2

2-(methylsulfanyl)-4-phenylpyrimidine

Conditions
ConditionsYield
Stage #1: 2-Methylthiouracil With triethylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate In 1,4-dioxane at 20℃; for 2h; Inert atmosphere; Sealed tube;
Stage #2: phenylboronic acid With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate In 1,4-dioxane; water at 100℃; for 4h; Suzuki coupling; Inert atmosphere; Sealed tube; chemoselective reaction;
99%
2-Methylthiouracil
5751-20-2

2-Methylthiouracil

5-iodo-4-hydroxy-6-methyl-2-methylthiopyrimidine
76510-61-7

5-iodo-4-hydroxy-6-methyl-2-methylthiopyrimidine

Conditions
ConditionsYield
With N-iodo-succinimide In chloroform at 70℃; for 2h;97%
With iodine; sodium hydroxide In water at 80℃; for 7h;87%
With sodium hydroxide; iodine In water at 80℃; for 7h;84%
With N-iodo-succinimide In chloroform at 70℃; Inert atmosphere;50%
2-Methylthiouracil
5751-20-2

2-Methylthiouracil

4-Aminobenzonitrile
873-74-5

4-Aminobenzonitrile

4-((4-hydroxypyrimidin-2-yl)amino)benzonitrile
189956-45-4

4-((4-hydroxypyrimidin-2-yl)amino)benzonitrile

Conditions
ConditionsYield
With pyridine at 110℃; for 8h; Reagent/catalyst; Temperature; Industrial scale;97%
2-Methylthiouracil
5751-20-2

2-Methylthiouracil

aniline
62-53-3

aniline

2-(phenylamino)pyrimidin-4(3H)-one
158661-55-3

2-(phenylamino)pyrimidin-4(3H)-one

Conditions
ConditionsYield
In diethylene glycol dimethyl ether Heating;96%
In diethylene glycol dimethyl ether at 170℃; for 5h;46%
2-Methylthiouracil
5751-20-2

2-Methylthiouracil

3,4,5-trimethoxyphenylboronic Acid
182163-96-8

3,4,5-trimethoxyphenylboronic Acid

2-(methylsulfanyl)-4-(3,4,5-trimethoxyphenyl)pyrimidine
1388177-39-6

2-(methylsulfanyl)-4-(3,4,5-trimethoxyphenyl)pyrimidine

Conditions
ConditionsYield
Stage #1: 2-Methylthiouracil With triethylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate In 1,4-dioxane at 20℃; for 2h; Inert atmosphere; Sealed tube;
Stage #2: 3,4,5-trimethoxyphenylboronic Acid With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate In 1,4-dioxane; water at 100℃; for 4h; Suzuki coupling; Inert atmosphere; Sealed tube; chemoselective reaction;
96%
2-Methylthiouracil
5751-20-2

2-Methylthiouracil

p-toluidine
106-49-0

p-toluidine

2-<(4-methylphenyl)amino>pyrimidin-4(3H)-one

2-<(4-methylphenyl)amino>pyrimidin-4(3H)-one

Conditions
ConditionsYield
In diethylene glycol dimethyl ether Heating;94%
With Trimethylacetic acid at 130℃; Inert atmosphere;
2-Methylthiouracil
5751-20-2

2-Methylthiouracil

3-biphenyl amine
2243-47-2

3-biphenyl amine

2-(3-biphenylamino)pyrimidin-4(3H)-one
960243-28-1

2-(3-biphenylamino)pyrimidin-4(3H)-one

Conditions
ConditionsYield
In diethylene glycol dimethyl ether for 18h; Heating / reflux;92%
In diethylene glycol dimethyl ether for 18h; Heating / reflux;92%
2-Methylthiouracil
5751-20-2

2-Methylthiouracil

1-amino-3-methylbenzene
108-44-1

1-amino-3-methylbenzene

2-<(3-methylphenyl)amino>pyrimidin-4(3H)-one

2-<(3-methylphenyl)amino>pyrimidin-4(3H)-one

Conditions
ConditionsYield
In diethylene glycol dimethyl ether Heating;90%
2-Methylthiouracil
5751-20-2

2-Methylthiouracil

4-Chloro-2-methylthiopyrimidine
49844-90-8

4-Chloro-2-methylthiopyrimidine

Conditions
ConditionsYield
With thionyl chloride In dichloromethane; N,N-dimethyl-formamide at 40℃; for 3h;87.6%
With thionyl chloride; N,N-dimethyl-formamide In dichloromethane at 40℃; for 3h;87.6%
With trichlorophosphate
With trichlorophosphate
2-Methylthiouracil
5751-20-2

2-Methylthiouracil

2-methylsulfanyl-5-bromopyrimidin-4-one
81560-03-4

2-methylsulfanyl-5-bromopyrimidin-4-one

Conditions
ConditionsYield
With N-Bromosuccinimide In dichloromethane for 6h; Reflux;87%
With potassium hydroxide; bromine; sodium bromide In 1,4-dioxane at 70℃; for 1h;75%
With bromine; acetic acid at 0 - 20℃; for 16h;62%
2-Methylthiouracil
5751-20-2

2-Methylthiouracil

acrylonitrile
107-13-1

acrylonitrile

3-(2-cyanoethyl)-2-methylthiopyrimidin-4-one
17994-74-0

3-(2-cyanoethyl)-2-methylthiopyrimidin-4-one

Conditions
ConditionsYield
With pyridine for 7h; Heating;86%
2-Methylthiouracil
5751-20-2

2-Methylthiouracil

tributyl(thien-2-yl)stannane
54663-78-4

tributyl(thien-2-yl)stannane

2-thiophen-2-yl-3H-pyrimidin-4-one
125903-92-6

2-thiophen-2-yl-3H-pyrimidin-4-one

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); copper(I) bromide dimethylsulfide complex In tetrahydrofuran for 24h; Liebeskind-Srogl cross-coupling; Inert atmosphere; Reflux;84%
2-Methylthiouracil
5751-20-2

2-Methylthiouracil

3-amino-4-methyl benzoic acid methyl ester
18595-18-1

3-amino-4-methyl benzoic acid methyl ester

methyl 3-(4-oxopyrimidin-2-ylamino)-4-methylbenzoate
1451042-82-2

methyl 3-(4-oxopyrimidin-2-ylamino)-4-methylbenzoate

Conditions
ConditionsYield
With hydrogenchloride In water at 130 - 160℃; for 1.5h; Reagent/catalyst; Temperature; Time; Inert atmosphere;84%
2-Methylthiouracil
5751-20-2

2-Methylthiouracil

4-bromo-2-methylsulfanylpyrimidine
959236-97-6

4-bromo-2-methylsulfanylpyrimidine

Conditions
ConditionsYield
With phosphorus(V) oxybromide In acetonitrile at 80℃; for 5h;83%
2-Methylthiouracil
5751-20-2

2-Methylthiouracil

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

3-(3-bromopropyl)-S-methyl-2-thiouracil
122182-81-4

3-(3-bromopropyl)-S-methyl-2-thiouracil

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide 1h, RT; 60 deg C, 24 h;82%
2-Methylthiouracil
5751-20-2

2-Methylthiouracil

4-chloro-aniline
106-47-8

4-chloro-aniline

2-<(4-chlorophenyl)amino>pyrimidin-4(3H)-one

2-<(4-chlorophenyl)amino>pyrimidin-4(3H)-one

Conditions
ConditionsYield
In diethylene glycol dimethyl ether Heating;79%
With 2-ethoxy-ethanol
With Trimethylacetic acid at 130℃; Inert atmosphere;
2-Methylthiouracil
5751-20-2

2-Methylthiouracil

4-amino-benzoic acid
150-13-0

4-amino-benzoic acid

4-(6-oxo-1,6-dihydro-pyrimidin-2-ylamino)-benzoic acid
919116-69-1

4-(6-oxo-1,6-dihydro-pyrimidin-2-ylamino)-benzoic acid

Conditions
ConditionsYield
In diglyme (diethyleneglycol dimethylether) for 16h; Heating / reflux;79%
In diethylene glycol dimethyl ether for 16h; Heating / reflux;
2-Methylthiouracil
5751-20-2

2-Methylthiouracil

3-chloro-aniline
108-42-9

3-chloro-aniline

2-<(3-chlorophenyl)amino>pyrimidin-4(3H)-one

2-<(3-chlorophenyl)amino>pyrimidin-4(3H)-one

Conditions
ConditionsYield
In diethylene glycol dimethyl ether Heating;77%
In diethylene glycol dimethyl ether for 18h; Heating / reflux;66%
2-Methylthiouracil
5751-20-2

2-Methylthiouracil

3,4-(methylenedioxy)-benzeneboronic acid
94839-07-3

3,4-(methylenedioxy)-benzeneboronic acid

4-(benzo[d][1,3]dioxol-5-yl)-2-(methylsulfanyl)pyrimidine
1388177-38-5

4-(benzo[d][1,3]dioxol-5-yl)-2-(methylsulfanyl)pyrimidine

Conditions
ConditionsYield
Stage #1: 2-Methylthiouracil With triethylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate In 1,4-dioxane at 20℃; for 2h; Inert atmosphere; Sealed tube;
Stage #2: 3,4-(methylenedioxy)-benzeneboronic acid With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate In 1,4-dioxane; water at 100℃; for 4h; Suzuki coupling; Inert atmosphere; Sealed tube; chemoselective reaction;
77%

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