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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

2-Acetyl-5-chlorothiophene Manufacturer/High quality/Best price/In stock

Cas:6310-09-4

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 1-(5-chloro-2-thienyl)ethan-1-one

Cas:6310-09-4

Min.Order:1

Negotiable

Type:Other

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2-Acetyl-5-chlorothiophene

Cas:6310-09-4

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Top Purity CAS 6310-09-4 with fast shipping

Cas:6310-09-4

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:powder Storage:Store in sealed containers at cool & dry plac

2-Acetyl-5-chlorothiophene/C6H5ClOS CAS 6310-09-4

Cas:6310-09-4

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Ethanone,1-(5-chloro-2-thienyl)- 6310-09-4

Cas:6310-09-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

2-ACETYL-5-CHLOROTHIOPHENE CAS:6310-09-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic

2-ACETYL-5-CHLOROTHIOPHENE CAS:6310-09-4

Cas:6310-09-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Ethanone,1-(5-chloro-2-thienyl)-

Cas:6310-09-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Ethanone,1-(5-chloro-2-thienyl)-

Cas:6310-09-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

5-CHLOR-2-ACETYL THIOPHEN

Cas:6310-09-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

5-Chloro-2-Acetylthiophene

Cas:6310-09-4

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2-acetyl-5-bromothiophene

Cas:6310-09-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

2-Acetyl-5-chlorothiophene

Cas:6310-09-4

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung, LG, Merck, Thermo Fisher Scientific and so o

Ethanone,1-(5-chloro-2-thienyl)-

Cas:6310-09-4

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: 5-Chloro-2-Acetylthiophene CAS No.:6310-09-4 Molecule Formula:C6H5ClOS Molecule Weight:160.62 Purity: 97.0% Package: 25kg/drum Description:White or off-white powder Manufacture Standards:Enterprise Standard TESTING

High Quality 5-Chloro-2-Acetylthiophene in stock

Cas:6310-09-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

2-ACETYL-5-CHLOROTHIOPHENE Basic information Product Name: 2-ACETYL-5-CHLOROTHIOPHENE Synonyms: 1-(5-chloro-2-thienyl)ethan-1-one;1-(5-Chloro-thiophen-2-yl)-ethanone;5-CHLORO-2-THIENYL METHYL KETONE;5-CHLORO-2-ACETYLTHIOPHENE;2-Acetyl-5-chlorot

2-ACETYL-5-CHLOROTHIOPHENE

Cas:6310-09-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou ZeErRui Chemical Co., Ltd.

Name: 2-ACETYL-5-CHLOROTHIOPHENE. Synonym:1-(5-chloro-2-thienyl)ethan-1-one;1-(5-Chloro-thiophen-2-yl)-ethanone;5-CHLORO-2-THIENYLMETHYLKETONE;5-CHLORO-2-ACETYLTHIOPHENE;2-Acetyl-5-chlorothiophene,99%;2-Acetyl-5-chlorothiophene,5-Chloro-2-thienyl

5-Chloro-2-Acetylthiophene manufacture

Cas:6310-09-4

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

5-Chloro-2-acetylthiophene

Cas:6310-09-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

5-CHLORO-2-ACETYLTHIOPHENE cas no. 6310-09-4 98%

Cas:6310-09-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

5-Chloro-2-Acetylthiophen

Cas:6310-09-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec 2-Acetyl-5-Chlorothiophene 100g

Cas:6310-09-4

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Taiho Chemical Co.,LTD

TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp

5-Chlor-2-Acetyl Thiophen

Cas:6310-09-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

2-ACETYL-5-CHLOROTHIOPHENE

Cas:6310-09-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hangzhou Fandachem Co.,Ltd

FandaChem,a China-based chemical company, specialize in exporting 2-Acetyl-5-chlorothiophene cas no 6310-09-4 Please contact us by email freely. Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG

2-Acetyl-5-chlorothiophene cas no 6310-09-4

Cas:6310-09-4

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Nanjing Fred Technology Co.,Ltd.

Fredchem focus on CRO/CMO business and its own R&D of API/Intermediates Package:Kilograms/MT Application:Pharmaceutical field Transportation:According to customer request Port:Shanghai

2-acetyl-5-chlorothiophene

Cas:6310-09-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Ethanone,1-(5-chloro-2-thienyl)-

Cas:6310-09-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

high purity Storage:normal temperature Package:DRUM Application:mainly for medical use for R&Dpurpose use only Transportation:AIR,SEA Port:BEIJING,SHANGHAI,TIANJIN,SHENZHEN

Enke 2-Acetyl-5-chlorothiophene

Cas:6310-09-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

DB BIOTECH CO., LTD

best seller Application:API

2-ACETYL-5-CHLOROTHIOPHENE

Cas:6310-09-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

2-ACETYL-5-CHLOROTHIOPHENE

Cas:6310-09-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SAGECHEM LIMITED

6310-09-4 Application:intermediate

5-Chloro-2-acetylthiophen

Cas:6310-09-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

5-chloro-2-(α-methoxyimino)ethylthiophene
114774-04-8

5-chloro-2-(α-methoxyimino)ethylthiophene

2-acetyl-5-chlorothiophene
6310-09-4

2-acetyl-5-chlorothiophene

Conditions
ConditionsYield
With hydrogenchloride at 70℃; for 8h;96%
2-thienyl chloride
96-43-5

2-thienyl chloride

acetyl chloride
75-36-5

acetyl chloride

2-acetyl-5-chlorothiophene
6310-09-4

2-acetyl-5-chlorothiophene

Conditions
ConditionsYield
With ytterbium(III) triflate In nitromethane at 20℃; for 4h; Friedel-Crafts acylation;90%
With zinc trifluoromethanesulfonate In nitromethane at 20℃; for 4h; Friedel-Crafts acylation;87%
With tetrachloromethane; aluminium trichloride
With aluminium trichloride; Petroleum ether Behandeln des Reaktionsprodukts mit Wasser;
Stage #1: acetyl chloride With aluminum (III) chloride In tetrachloromethane at 0℃; for 0.333333h; Friedel Crafts Acylation;
Stage #2: 2-thienyl chloride In tetrachloromethane at 0℃; for 1.58333h; Friedel Crafts Acylation;
Stage #3: With hydrogenchloride; water In tetrachloromethane
2-thienyl chloride
96-43-5

2-thienyl chloride

acetic anhydride
108-24-7

acetic anhydride

2-acetyl-5-chlorothiophene
6310-09-4

2-acetyl-5-chlorothiophene

Conditions
ConditionsYield
With perchloric acid at 0 - 20℃; for 6.5h;81%
activated clay at 45 - 55℃; for 73h;52%
With phosphoric acid
2-Acetylthiophene
88-15-3

2-Acetylthiophene

A

2-acetyl-5-chlorothiophene
6310-09-4

2-acetyl-5-chlorothiophene

B

2-acetyl-5-iodothiophene
30955-94-3

2-acetyl-5-iodothiophene

Conditions
ConditionsYield
With N,N,N-trimethylbenzenemethanaminium dichloroiodate; zinc(II) chloride In acetic acid at 70℃; for 24h;A 69%
B 7%
With N,N,N-trimethylbenzenemethanaminium dichloroiodate; zinc(II) chloride In acetic acid at 70℃; for 24h; Product distribution; with different molar ratio;A 47%
B 22%
With N,N,N-trimethylbenzenemethanaminium dichloroiodate; zinc(II) chloride In acetic acid at 70℃; for 24h;A 47%
B 22%
2-thienyl chloride
96-43-5

2-thienyl chloride

acetic anhydride
108-24-7

acetic anhydride

trifluoroborane diethyl ether
109-63-7

trifluoroborane diethyl ether

A

2-acetyl-5-chlorothiophene
6310-09-4

2-acetyl-5-chlorothiophene

B

1-(5-chloro-[2]thienyl)-butane-1,3-dione

1-(5-chloro-[2]thienyl)-butane-1,3-dione

C

(E)-1,3-bis-(5-chlorothien-2-yl)but-2-en-1-one

(E)-1,3-bis-(5-chlorothien-2-yl)but-2-en-1-one

C6H4(3)HClOS

C6H4(3)HClOS

2-acetyl-5-chlorothiophene
6310-09-4

2-acetyl-5-chlorothiophene

Conditions
ConditionsYield
sodium hydroxide at 25℃; Rate constant;
2-Acetylthiophene
88-15-3

2-Acetylthiophene

2-acetyl-5-chlorothiophene
6310-09-4

2-acetyl-5-chlorothiophene

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 81 percent / Na2CO3, AcOH / methanol; H2O / 2 h / Heating; pH 4.5
2: 62 percent / Fe, Cl2 / CHCl3 / 3 h / Heating
3: 96 percent / 25percent HCl / 8 h / 70 °C
View Scheme
Multi-step reaction with 4 steps
1: 98 percent / NH2OH*HCl, Na2CO3, AcOH / methanol; H2O / 2 h / Heating
2: 95 percent / NaOH / dimethylformamide; H2O / 0.5 h / 10 °C
3: 62 percent / Fe, Cl2 / CHCl3 / 3 h / Heating
4: 96 percent / 25percent HCl / 8 h / 70 °C
View Scheme
2-acetylthiophene oxime
1956-45-2, 92313-45-6, 92313-54-7

2-acetylthiophene oxime

2-acetyl-5-chlorothiophene
6310-09-4

2-acetyl-5-chlorothiophene

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 95 percent / NaOH / dimethylformamide; H2O / 0.5 h / 10 °C
2: 62 percent / Fe, Cl2 / CHCl3 / 3 h / Heating
3: 96 percent / 25percent HCl / 8 h / 70 °C
View Scheme
2-(α-methoxyimino)ethylthiophene
114773-97-6

2-(α-methoxyimino)ethylthiophene

2-acetyl-5-chlorothiophene
6310-09-4

2-acetyl-5-chlorothiophene

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 62 percent / Fe, Cl2 / CHCl3 / 3 h / Heating
2: 96 percent / 25percent HCl / 8 h / 70 °C
View Scheme
5-chloro-2-(α-methoxyimino)ethylthiophene

5-chloro-2-(α-methoxyimino)ethylthiophene

2-acetyl-5-chlorothiophene
6310-09-4

2-acetyl-5-chlorothiophene

Conditions
ConditionsYield
With hydrogenchloride
2-acetyl-5-chlorothiophene
6310-09-4

2-acetyl-5-chlorothiophene

2-Methylphenylboronic acid
16419-60-6

2-Methylphenylboronic acid

1‐[5‐(2‐methylphenyl)‐2‐thienyl]ethanone

1‐[5‐(2‐methylphenyl)‐2‐thienyl]ethanone

Conditions
ConditionsYield
With potassium fluoride; tris(dibenzylideneacetone)dipalladium (0); tri-tert-butyl phosphine In tetrahydrofuran; hexane at 20℃; for 7h; Suzuki cross-coupling;99%
With potassium phosphate monohydrate; 2‐(dicyclohexylphosphino)‐N,N‐diisopropyl‐5,6‐dimethyl‐1H‐benzo[d]imidazole‐1‐carboxamide; palladium diacetate In tetrahydrofuran at 110℃; for 24h; Suzuki-Miyaura Coupling; Schlenk technique; Inert atmosphere; Sealed tube;98%
With potassium methanolate; tetrabutylammomium bromide; 1,3-bis[2,6-diisopropylphenyl]imidazolium chloride; bis(dibenzylideneacetone)-palladium(0) In methanol; toluene at 40℃; for 29h; Suzuki-Miyaura cross-coupling reaction;61%
2-acetyl-5-chlorothiophene
6310-09-4

2-acetyl-5-chlorothiophene

trans-2-phenylvinylboronic acid
6783-05-7

trans-2-phenylvinylboronic acid

trans-2-acetyl-5-(β-phenylvinyl)thiophene
125972-78-3

trans-2-acetyl-5-(β-phenylvinyl)thiophene

Conditions
ConditionsYield
With potassium carbonate; 3-Cl-pyridine-Pd-{CH-[N-(2,6-di-iPrC6H3)-CH]2}Cl2 In 1,4-dioxane at 60℃; for 6h; Suzuki-Miyaura reaction;99%
With tris-(dibenzylideneacetone)dipalladium(0); potassium fluoride dihydrate; tri-tert-butylphosphonium tetrafluoroborate In tetrahydrofuran at 20℃; Suzuki cross-coupling; Inert atmosphere;90%
2-acetyl-5-chlorothiophene
6310-09-4

2-acetyl-5-chlorothiophene

Dihydroxy-styryl-boran
4363-35-3, 6783-05-7, 60806-02-2

Dihydroxy-styryl-boran

trans-2-acetyl-5-(β-phenylvinyl)thiophene
125972-78-3

trans-2-acetyl-5-(β-phenylvinyl)thiophene

Conditions
ConditionsYield
With potassium carbonate; [1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene](3-chloropyridyl)palladium(II) dichloride In 1,4-dioxane at 60℃; for 6h; Product distribution / selectivity; Suzuki Coupling;99%
2-acetyl-5-chlorothiophene
6310-09-4

2-acetyl-5-chlorothiophene

2-(tributylstannyl)furan
118486-94-5

2-(tributylstannyl)furan

1-(5-(furan-2-yl)-thiophen-2-yl)ethanone
879896-51-2

1-(5-(furan-2-yl)-thiophen-2-yl)ethanone

Conditions
ConditionsYield
With trans-dichloro(1,3-bis-(2,6-diisopentylphenyl)imidazolylidinium)(3-chloro-pyridine); cesium fluoride In 1,4-dioxane at 20 - 80℃; for 16h; Stille-Migita cross-coupling; Molecular sieve; Inert atmosphere;99%
2-acetyl-5-chlorothiophene
6310-09-4

2-acetyl-5-chlorothiophene

ethyl acetoacetate
141-97-9

ethyl acetoacetate

malononitrile
109-77-3

malononitrile

6-amino-4-(5-chlorothiophen-2-yl)-2,4-dihydro-3,4-dimethylpyrano[2,3-c]pyrazole-5-carbonitrile
1235990-64-3

6-amino-4-(5-chlorothiophen-2-yl)-2,4-dihydro-3,4-dimethylpyrano[2,3-c]pyrazole-5-carbonitrile

Conditions
ConditionsYield
With hydrazine hydrate; heptakis(6-amino-6-deoxy)-β-cyclodextrin at 20℃; for 0.0166667h; Neat (no solvent);99%
2-acetyl-5-chlorothiophene
6310-09-4

2-acetyl-5-chlorothiophene

4-chlorobenzaldehyde
104-88-1

4-chlorobenzaldehyde

(2E)-1-(4-chlorocyclopenta-1,3-dien-1-yl)-3-(4-chlorophenyl)prop-2-en-1-one
96583-49-2

(2E)-1-(4-chlorocyclopenta-1,3-dien-1-yl)-3-(4-chlorophenyl)prop-2-en-1-one

Conditions
ConditionsYield
With potassium hydroxide In ethanol; water at 20℃; for 4h;98%
With potassium hydroxide In methanol at 25℃; for 2h; Condensation;93%
With sodium hydroxide
2-acetyl-5-chlorothiophene
6310-09-4

2-acetyl-5-chlorothiophene

4-dimethylamino-benzaldehyde
100-10-7

4-dimethylamino-benzaldehyde

(2E)-1-(4-chlorocyclopenta-1,3-dien-1-yl)-3-[4-(dimethylamino)phenyl]prop-2-en-1-one
107058-33-3

(2E)-1-(4-chlorocyclopenta-1,3-dien-1-yl)-3-[4-(dimethylamino)phenyl]prop-2-en-1-one

Conditions
ConditionsYield
With potassium hydroxide In ethanol; water at 20℃; for 4h;98%
With potassium hydroxide In ethanol; water at 20℃; for 48h; Claisen-Schmidt Condensation;79%
With sodium hydroxide; ethanol
4-Trifluoromethylbenzaldehyde
455-19-6

4-Trifluoromethylbenzaldehyde

2-acetyl-5-chlorothiophene
6310-09-4

2-acetyl-5-chlorothiophene

(2E)-1-(4-chlorocyclopenta-1,3-dien-1-yl)-3-[4-(trifluoromethyl)phenyl]prop-2-en-1-one

(2E)-1-(4-chlorocyclopenta-1,3-dien-1-yl)-3-[4-(trifluoromethyl)phenyl]prop-2-en-1-one

Conditions
ConditionsYield
With potassium hydroxide In ethanol; water at 20℃; for 4h;98%
With sodium hydroxide In ethanol; water at 20℃; for 1h; Inert atmosphere;18%
2-acetyl-5-chlorothiophene
6310-09-4

2-acetyl-5-chlorothiophene

4-ethylbenzylaldehyde
4748-78-1

4-ethylbenzylaldehyde

(2E)-1-(4-chlorocyclopenta-1,3-dien-1-yl)-3-(4-ethylphenyl)prop-2-en-1-one

(2E)-1-(4-chlorocyclopenta-1,3-dien-1-yl)-3-(4-ethylphenyl)prop-2-en-1-one

Conditions
ConditionsYield
With potassium hydroxide In ethanol; water at 20℃; for 4h;98%
2-acetyl-5-chlorothiophene
6310-09-4

2-acetyl-5-chlorothiophene

4-bromo-benzaldehyde
1122-91-4

4-bromo-benzaldehyde

(2E)-3-(4-bromophenyl)-1-(4-chlorocyclopenta-1,3-dien-1-yl)prop-2-en-1-one

(2E)-3-(4-bromophenyl)-1-(4-chlorocyclopenta-1,3-dien-1-yl)prop-2-en-1-one

Conditions
ConditionsYield
With potassium hydroxide In ethanol; water at 20℃; for 4h;98%
2-acetyl-5-chlorothiophene
6310-09-4

2-acetyl-5-chlorothiophene

β-naphthaldehyde
66-99-9

β-naphthaldehyde

(2E)-1-(5-chlorothiophen-2-yl)-3-(naphthalen-2-yl)prop-2-en-1-one
1352445-09-0

(2E)-1-(5-chlorothiophen-2-yl)-3-(naphthalen-2-yl)prop-2-en-1-one

Conditions
ConditionsYield
With potassium hydroxide In methanol at 20℃; for 24h; Aldol condensation;97%
With sodium hydroxide In methanol at 20℃;
2-acetyl-5-chlorothiophene
6310-09-4

2-acetyl-5-chlorothiophene

potassium phenyltrifluoborate

potassium phenyltrifluoborate

5-phenyl-2-acetylthiophene
1665-41-4

5-phenyl-2-acetylthiophene

Conditions
ConditionsYield
With N-methyl-2-phenyl-3-(dicyclohexylphosphino)-1H-indole; palladium diacetate; potassium carbonate; triethylamine In water at 100℃; for 18h; Suzuki-Miyaura Coupling; Inert atmosphere; Schlenk technique;97%
2-acetyl-5-chlorothiophene
6310-09-4

2-acetyl-5-chlorothiophene

sodium 4-methylbenzenesulfinate
824-79-3

sodium 4-methylbenzenesulfinate

1-(5-tosylthiophen-2-yl)ethan-1-one
1354558-40-9

1-(5-tosylthiophen-2-yl)ethan-1-one

Conditions
ConditionsYield
In dimethyl sulfoxide at 110℃; for 20h;96%
With quinoline; copper(l) chloride In 1-methyl-pyrrolidin-2-one at 140℃; for 0.1h; Microwave irradiation;85%
2-acetyl-5-chlorothiophene
6310-09-4

2-acetyl-5-chlorothiophene

oxalic acid diethyl ester
95-92-1

oxalic acid diethyl ester

ethyl 5-(5-chlorothiophen-2-yl)isoxazole-3-carboxylate
323594-72-5

ethyl 5-(5-chlorothiophen-2-yl)isoxazole-3-carboxylate

Conditions
ConditionsYield
With hydroxylamine hydrochloride96%
2-acetyl-5-chlorothiophene
6310-09-4

2-acetyl-5-chlorothiophene

phenylhydrazine
100-63-0

phenylhydrazine

C12H11ClN2S

C12H11ClN2S

Conditions
ConditionsYield
With acetic acid In ethanol at 20℃; for 33h;96%
2-acetyl-5-chlorothiophene
6310-09-4

2-acetyl-5-chlorothiophene

2-chloro-6-methoxyquinolin-3-carboxaldehyde
73568-29-3

2-chloro-6-methoxyquinolin-3-carboxaldehyde

(2E)-3-(2-chloro-6-methoxyquinolin-3-yl)-1-(5-chlorothien-2-yl)prop-2-en-1-one
1253278-27-1

(2E)-3-(2-chloro-6-methoxyquinolin-3-yl)-1-(5-chlorothien-2-yl)prop-2-en-1-one

Conditions
ConditionsYield
With sodium hydroxide In methanol; water at 20℃; for 2h; Claisen Schmidt condensation;95%
With sodium hydroxide In ethanol; water
2-acetyl-5-chlorothiophene
6310-09-4

2-acetyl-5-chlorothiophene

phenylboronic acid
98-80-6

phenylboronic acid

5-phenyl-2-acetylthiophene
1665-41-4

5-phenyl-2-acetylthiophene

Conditions
ConditionsYield
With [Pd(3-[(2,6-diisopropylphenyl)-1-imidazolio]-2-quinoxalinide)(PPh3)Cl2]; potassium carbonate; triphenylphosphine In water at 100℃; for 3h; Suzuki-Miyaura Coupling;95%
With 4,5-dimethyl-3-(2-phenoxyphenyl)-1-(2,4,6-trimethylbenzyl)imidazolium chloride; palladium diacetate; caesium carbonate In 1,4-dioxane at 90℃; for 18h; Suzuki-Miyaura Coupling; Inert atmosphere;81%
With potassium phosphate; C28H31ClN2Ni; triphenylphosphine In toluene; tert-butyl alcohol at 90℃; for 3.5h; Suzuki-Miyaura Coupling; Inert atmosphere; Sealed tube;47%
furfural
98-01-1

furfural

2-acetyl-5-chlorothiophene
6310-09-4

2-acetyl-5-chlorothiophene

1-(5-chlorothiophen-2-yl)-3-(furan-2-yl)propenone

1-(5-chlorothiophen-2-yl)-3-(furan-2-yl)propenone

Conditions
ConditionsYield
With potassium hydroxide In methanol; water at 0℃; Claisen Schmidt condensation;94.21%
Stage #1: furfural With potassium hydroxide In methanol; water at 0℃; for 0.166667h;
Stage #2: 2-acetyl-5-chlorothiophene In methanol; water at 0℃; for 3h;
92%
With potassium hydroxide In methanol; water at 0℃;
furan-3-carboxaldehyde
498-60-2

furan-3-carboxaldehyde

2-acetyl-5-chlorothiophene
6310-09-4

2-acetyl-5-chlorothiophene

1-(5-chlorothiophen-2-yl)-3-(furan-3-yl)propenone
1204578-99-3

1-(5-chlorothiophen-2-yl)-3-(furan-3-yl)propenone

Conditions
ConditionsYield
With potassium hydroxide In methanol; water at 0℃; Claisen Schmidt condensation;94.21%
With potassium hydroxide In methanol; water at 0℃;
thiophene-2-carbaldehyde
98-03-3

thiophene-2-carbaldehyde

2-acetyl-5-chlorothiophene
6310-09-4

2-acetyl-5-chlorothiophene

4-Chloro-3-nitroaniline
635-22-3

4-Chloro-3-nitroaniline

C17H12Cl2N2O3S2
1037752-15-0

C17H12Cl2N2O3S2

Conditions
ConditionsYield
With hydrogenchloride In ethanol at 0 - 50℃; Mannich reaction;94.2%
2-acetyl-5-chlorothiophene
6310-09-4

2-acetyl-5-chlorothiophene

(E)-1-(5-chlorothiophen-2-yl)ethan-1-one oxime
42520-87-6

(E)-1-(5-chlorothiophen-2-yl)ethan-1-one oxime

Conditions
ConditionsYield
With hydroxylamine hydrochloride; sodium acetate In ethanol at 20 - 80℃; for 16h;94%
With hydroxylamine
With hydroxylamine hydrochloride; sodium acetate In ethanol; water for 3h; Reflux;
With hydroxylamine hydrochloride; sodium acetate In ethanol; water for 3h; Reflux;
2-acetyl-5-chlorothiophene
6310-09-4

2-acetyl-5-chlorothiophene

4-methoxy-benzaldehyde
123-11-5

4-methoxy-benzaldehyde

(2E)-1-(4-chlorocyclopenta-1,3-dien-1-yl)-3-(4-methoxyphenyl)prop-2-en-1-one

(2E)-1-(4-chlorocyclopenta-1,3-dien-1-yl)-3-(4-methoxyphenyl)prop-2-en-1-one

Conditions
ConditionsYield
With potassium hydroxide In ethanol; water at 20℃; for 4h;94%
With sodium hydroxide In methanol at 20℃;72%
With sodium hydroxide In methanol at 0 - 5℃;
With sodium hydroxide In methanol; water at 0 - 5℃; pH=10 - 11;
Thien-3-ylboronic acid
6165-69-1

Thien-3-ylboronic acid

2-acetyl-5-chlorothiophene
6310-09-4

2-acetyl-5-chlorothiophene

1-([2,3′-bithiophen]-5-yl)ethanone
98946-35-1

1-([2,3′-bithiophen]-5-yl)ethanone

Conditions
ConditionsYield
With potassium phosphate; C46H52Cl3N3O2Pd In tetrahydrofuran; water at 60℃; for 4h; Suzuki-Miyaura Coupling;94%
With bis(η3-allyl-μ-chloropalladium(II)); 4,5-dimethyl-3-(2-phenoxyphenyl)-1-(2,4,6-trimethylbenzyl)imidazolium chloride; caesium carbonate In 1,4-dioxane at 100℃; for 18h; Suzuki-Miyaura Coupling; Inert atmosphere;74%
methanol
67-56-1

methanol

2-acetyl-5-chlorothiophene
6310-09-4

2-acetyl-5-chlorothiophene

1-(5-methoxythiophen-2-yl)ethan-1-one
30009-72-4

1-(5-methoxythiophen-2-yl)ethan-1-one

Conditions
ConditionsYield
With t-BuBrettPhos; [(2-di-tert-butylphosphino-3,6-dimethoxy-2’,4’,6’-triisopropyl-1,1’-biphenyl)-2-(2’-amino-1,1‘-biphenyl)]palladium(II) methanesulfonate; caesium carbonate In 1,4-dioxane at 50℃; for 20h; Sealed tube; Inert atmosphere;94%
With [(2-di-cyclohexylphosphino-3,6-dimethoxy-2’,4’,6’-triisopropyl-1,1‘-biphenyl)-2-(2‘-amino-1,1’-biphenyl)]palladium(II) methanesulfonate; caesium carbonate at 100℃; for 1h; Sealed tube; Microwave irradiation;33%
2-acetyl-5-chlorothiophene
6310-09-4

2-acetyl-5-chlorothiophene

(S)-1-(5-chlorothiophen-2-yl)ethan-1-ol

(S)-1-(5-chlorothiophen-2-yl)ethan-1-ol

Conditions
ConditionsYield
With triiron dodecarbonyl; C52H58N4P2; hydrogen; potassium hydroxide In methanol at 45℃; under 37503.8 Torr; for 10h; enantioselective reaction;94%
5-chloro-2-furaldehyde
21508-19-0

5-chloro-2-furaldehyde

2-acetyl-5-chlorothiophene
6310-09-4

2-acetyl-5-chlorothiophene

3-(5-chlorofuran-2-yl)-1-(5-chlorothiophen-2-yl)-propenone
1204579-00-9

3-(5-chlorofuran-2-yl)-1-(5-chlorothiophen-2-yl)-propenone

Conditions
ConditionsYield
With potassium hydroxide In methanol; water at 0℃; Claisen Schmidt condensation;93.99%
furfural
98-01-1

furfural

2-acetyl-5-chlorothiophene
6310-09-4

2-acetyl-5-chlorothiophene

4-nitro-aniline
100-01-6

4-nitro-aniline

C17H13ClN2O4S
1037752-12-7

C17H13ClN2O4S

Conditions
ConditionsYield
With hydrogenchloride In ethanol at 0 - 50℃; Mannich reaction;93.2%

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