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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

Alpha-methyl-l-p-tyrosine

Cas:672-87-7

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm

α-Methyl-L-tyrosine CAS NO.672-87-7

Cas:672-87-7

Min.Order:1 Metric Ton

FOB Price: $1.0 / 3.0

Type:Manufacturers

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price API 99% ALPHA-METHYL-L-P-TYROSINE 672-87-7 GMP Manufacturer

Cas:672-87-7

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Metyrosine

Cas:672-87-7

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Leader Biochemical Group

About Product Details

China Largest factory Manufacturer Supply ALPHA-METHYL-L-P-TYROSINE CAS 672-87-7

Cas:672-87-7

Min.Order:1 Kilogram

FOB Price: $3.0 / 10.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

672-87-7 ALPHA-METHYL-L-P-TYROSINE

Cas:672-87-7

Min.Order:1 Kilogram

FOB Price: $15.0 / 50.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 672-87-7 with competitive price

Cas:672-87-7

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the

L-Tyrosine, a-methyl-/ LIDE PHARMA- Factory supply / Best price

Cas:672-87-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

L-Tyrosine, a-methyl-

Cas:672-87-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

ALPHA-METHYL-L-P-TYROSINE CAS:672-87-7 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic i

ALPHA-METHYL-L-P-TYROSINE CAS:672-87-7

Cas:672-87-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

L-Tyrosine, a-methyl-

Cas:672-87-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

ALPHA-METHYL-L-P-TYROSINE

Cas:672-87-7

Min.Order:1 Kilogram

FOB Price: $10.0 / 100.0

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

ALPHA-METHYL-L-P-TYROSINE

Cas:672-87-7

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

(2S)-2-amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid

Cas:672-87-7

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

L-Tyrosine, a-methyl-

Cas:672-87-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

Alpha-methyl-l-p-tyrosine

Cas:672-87-7

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

ALPHA-METHYL-L-P-TYROSINE

Cas:672-87-7

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

hangzhou verychem science and technology co.ltd

Hangzhou Verychem Science And Technology Co. Ltd. was set up in year 2004, it’s a young but fast growing company. In the twelve years history, it invested two pharmaceutical raw material production plants, one researching company, and several

Metyrosine

Cas:672-87-7

Min.Order:1 Metric Ton

FOB Price: $80.0

Type:Manufacturers

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

Alpha-methyl-l-p-tyrosine Manufacturer/High quality/Best price/In stock

Cas:672-87-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Buy Top Purity ALPHA-METHYL-L-P-TYROSINE

Cas:672-87-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

ALPHA-METHYL-L-P-TYROSINE

Cas:672-87-7

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

ALPHA-METHYL-L-P-TYROSINE

Cas:672-87-7

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

ALPHA-METHYL-L-P-TYROSINE

Cas:672-87-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

ALPHA-METHYL-L-P-TYROSINE

Cas:672-87-7

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

Methyl-L-Tyr

Cas:672-87-7

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

SAGECHEM LIMITED

SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in custom synthe

SAGECHEM/α-methyl-L-tyrosine

Cas:672-87-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

L-alpha-Methyltyrosine

Cas:672-87-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

ALPHA-METHYL-L-P-TYROSINE

Cas:672-87-7

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

ALPHA-METHYL-L-P-TYROSINE

Cas:672-87-7

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Research Peptide Biotechnology Co., Ltd.

High purity, high success rate, short cycle and moderate priceAppearance:White powder solid Storage:Negative 20 degrees Celsius Package:5mg, 10mg 100mg, 1gram Application:Applied to various scientific research

L-Tyrosine, a-methyl-

Cas:672-87-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

(2S)-2-amino-3-(4-methoxyphenyl)-2-methyl-propionamide hydrogen bromide salt
1299492-19-5

(2S)-2-amino-3-(4-methoxyphenyl)-2-methyl-propionamide hydrogen bromide salt

L-methyltyrosine
672-87-7

L-methyltyrosine

Conditions
ConditionsYield
With water; hydrogen bromide at 105℃; for 17h; Product distribution / selectivity;86%
2-(S)-amino-3-(4-methoxyphenyl)-2-methylpropionamide
1299492-09-3

2-(S)-amino-3-(4-methoxyphenyl)-2-methylpropionamide

L-methyltyrosine
672-87-7

L-methyltyrosine

Conditions
ConditionsYield
With water; hydrogen bromide at 120℃; for 5h; Product distribution / selectivity;84%
Multi-step reaction with 2 steps
1: water; hydrogen bromide / methanol / 100 °C / 15 - 22.5 Torr
2: water; hydrogen bromide / 17 h / 105 °C
View Scheme
(2S)-2-amino-3-(4-methoxyphenyl)-2-methyl-propionamide hydrochloride
1299492-14-0

(2S)-2-amino-3-(4-methoxyphenyl)-2-methyl-propionamide hydrochloride

L-methyltyrosine
672-87-7

L-methyltyrosine

Conditions
ConditionsYield
With hydrogen bromide In water at 120℃; for 4h; Product distribution / selectivity;83%
(2S)-2-amino-3-(4-methoxyphenyl)-2-methylpropionamide formic acid salt
1299492-20-8

(2S)-2-amino-3-(4-methoxyphenyl)-2-methylpropionamide formic acid salt

L-methyltyrosine
672-87-7

L-methyltyrosine

Conditions
ConditionsYield
With water; hydrogen bromide at 105℃; for 17h; Product distribution / selectivity;82%
(S)-N2-benzoyl-O4',2-dimethyltyrosine

(S)-N2-benzoyl-O4',2-dimethyltyrosine

L-methyltyrosine
672-87-7

L-methyltyrosine

Conditions
ConditionsYield
With hydrogenchloride In 1,4-dioxane at 100℃; for 4h;75.4%
tert-butyl (2R)-2-amino-3-(4-methoxyphenyl)-2-methylpropanoate

tert-butyl (2R)-2-amino-3-(4-methoxyphenyl)-2-methylpropanoate

L-methyltyrosine
672-87-7

L-methyltyrosine

Conditions
ConditionsYield
Stage #1: tert-butyl (2R)-2-amino-3-(4-methoxyphenyl)-2-methylpropanoate With boron tribromide In dichloromethane at 20℃; for 1.5h;
Stage #2: With sodium hydrogencarbonate In dichloromethane; water Product distribution / selectivity;
45.4%
N-Chloroacetyl-α-methyltyrosine
121703-96-6

N-Chloroacetyl-α-methyltyrosine

A

L-methyltyrosine
672-87-7

L-methyltyrosine

B

α-methyl-D-tyrosine
672-86-6

α-methyl-D-tyrosine

C

N-Chloroacetyl-D-α-methyltyrosine
121704-37-8

N-Chloroacetyl-D-α-methyltyrosine

D

N-Chloroacetyl-L-α-methyltyrosine
121703-96-6, 121704-37-8

N-Chloroacetyl-L-α-methyltyrosine

Conditions
ConditionsYield
With potassium hydroxide; porcine kidney acylase I pH 7.5-8.0; Yields of byproduct given;A 30%
B n/a
C n/a
D n/a
With potassium hydroxide; porcine kidney acylase I pH 7.5-8.0; Yields of byproduct given;A n/a
B 30%
C n/a
D n/a
With potassium hydroxide; porcine kidney acylase I pH 7.5-8.0; Yield given. Yields of byproduct given;
α-methyl-β-p-methoxyphenyl-alanine
65555-88-6

α-methyl-β-p-methoxyphenyl-alanine

L-methyltyrosine
672-87-7

L-methyltyrosine

Conditions
ConditionsYield
With hydrogen bromide
N-Chloroacetyl-α-methyltyrosine
121703-96-6

N-Chloroacetyl-α-methyltyrosine

A

L-methyltyrosine
672-87-7

L-methyltyrosine

B

N-Chloroacetyl-D-α-methyltyrosine
121704-37-8

N-Chloroacetyl-D-α-methyltyrosine

Conditions
ConditionsYield
With potassium hydroxide; potassium phosphate buffer; porcine kidney acylase I at 40℃; relative initial rate of hydrolysis, also with Aspergillus acylase I as a catalyst; with or without CoCl2;
2-Nitro-2-(4-hydroxybenzyl)propionsaeureethylester
16109-65-2

2-Nitro-2-(4-hydroxybenzyl)propionsaeureethylester

L-methyltyrosine
672-87-7

L-methyltyrosine

Conditions
ConditionsYield
With hydrogen; platinum(IV) oxide; nickel 1.) MeOH, reflux, 1 h, 2.) MeOH, 28 h; Yield given. Multistep reaction;
(4-hydroxyphenyl)methanol
623-05-2

(4-hydroxyphenyl)methanol

L-methyltyrosine
672-87-7

L-methyltyrosine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 56.1 percent / tetrabutylammonium chloride, potassium fluoride dihydrate / toluene / 48 h / Heating
2: 2.) H2 / 1.) Raney-Ni, 2.) PtO2 / 1.) MeOH, reflux, 1 h, 2.) MeOH, 28 h
View Scheme
p-Methoxybenzyl bromide
2746-25-0

p-Methoxybenzyl bromide

L-methyltyrosine
672-87-7

L-methyltyrosine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: NaH / tetrahydrofuran / 0 - 25 °C
2: α-chymotrypsin / dimethylsulfoxide; H2O / 22 - 25 °C / potassium phosphate ( pH 7.0); with pig liver esterase the reaction rate is higher but the e.e. is lower
3: 1.) acyl azide formation, 2.) Curtius rearrangement
4: aq. HBr (48 percent)
View Scheme
2-<(4-methoxyphenyl)methyl>-2-methylpropanedioic acid, dimethyl ester
21118-89-8

2-<(4-methoxyphenyl)methyl>-2-methylpropanedioic acid, dimethyl ester

L-methyltyrosine
672-87-7

L-methyltyrosine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: α-chymotrypsin / dimethylsulfoxide; H2O / 22 - 25 °C / potassium phosphate ( pH 7.0); with pig liver esterase the reaction rate is higher but the e.e. is lower
2: 1.) acyl azide formation, 2.) Curtius rearrangement
3: aq. HBr (48 percent)
View Scheme
(R)-2-(4-Methoxy-benzyl)-2-methyl-malonic acid monomethyl ester
21186-54-9

(R)-2-(4-Methoxy-benzyl)-2-methyl-malonic acid monomethyl ester

L-methyltyrosine
672-87-7

L-methyltyrosine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 1.) acyl azide formation, 2.) Curtius rearrangement
2: aq. HBr (48 percent)
View Scheme
4-methoxybenzyl methyl ketone
122-84-9

4-methoxybenzyl methyl ketone

L-methyltyrosine
672-87-7

L-methyltyrosine

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: water; methanol / 20 h / 40 °C / Sealed tube
2.1: sulfuric acid / dichloromethane; water / 3.25 h / -10 - 0 °C / Cooling with ice
2.2: pH 8 - 9
3.1: ammonium formate / palladium on carbon / isopropyl alcohol / 1 h / Inert atmosphere; Reflux
4.1: water; hydrogen bromide / methanol / 100 °C / 15 - 22.5 Torr
5.1: water; hydrogen bromide / 17 h / 105 °C
View Scheme
Multi-step reaction with 4 steps
1.1: water; methanol / 20 h / 40 °C / Sealed tube
2.1: sulfuric acid / dichloromethane; water / 3.25 h / -10 - 0 °C / Cooling with ice
2.2: pH 8 - 9
3.1: palladium on carbon / water; methanol / 5.75 h / 20 - 60 °C
4.1: water; hydrogen bromide / 17 h / 105 °C
View Scheme
Multi-step reaction with 4 steps
1.1: water; methanol / 20 h / 40 °C / Sealed tube
2.1: sulfuric acid / dichloromethane; water / 3.25 h / -10 - 0 °C / Cooling with ice
2.2: pH 8 - 9
3.1: ammonium formate / palladium on carbon / isopropyl alcohol / 1 h / Inert atmosphere; Reflux
4.1: water; hydrogen bromide / 5 h / 120 °C
View Scheme
2-[1-(S)-cyano-2-(4-methoxyphenyl)-1-methylethylamino]-2-(R)-phenylacetamide
1299492-07-1

2-[1-(S)-cyano-2-(4-methoxyphenyl)-1-methylethylamino]-2-(R)-phenylacetamide

L-methyltyrosine
672-87-7

L-methyltyrosine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: sulfuric acid / dichloromethane; water / 3.25 h / -10 - 0 °C / Cooling with ice
1.2: pH 8 - 9
2.1: ammonium formate / palladium on carbon / isopropyl alcohol / 1 h / Inert atmosphere; Reflux
3.1: water; hydrogen bromide / methanol / 100 °C / 15 - 22.5 Torr
4.1: water; hydrogen bromide / 17 h / 105 °C
View Scheme
Multi-step reaction with 3 steps
1.1: sulfuric acid / dichloromethane; water / 3.25 h / -10 - 0 °C / Cooling with ice
1.2: pH 8 - 9
2.1: palladium on carbon / water; methanol / 5.75 h / 20 - 60 °C
3.1: water; hydrogen bromide / 17 h / 105 °C
View Scheme
Multi-step reaction with 3 steps
1.1: sulfuric acid / dichloromethane; water / 3.25 h / -10 - 0 °C / Cooling with ice
1.2: pH 8 - 9
2.1: ammonium formate / palladium on carbon / isopropyl alcohol / 1 h / Inert atmosphere; Reflux
3.1: water; hydrogen bromide / 5 h / 120 °C
View Scheme
2-[(R)-(carbamoylphenylmethyl)-amino]-3-(4-methoxyphenyl)-2-(S)-methylpropionamide
1299492-08-2

2-[(R)-(carbamoylphenylmethyl)-amino]-3-(4-methoxyphenyl)-2-(S)-methylpropionamide

L-methyltyrosine
672-87-7

L-methyltyrosine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: ammonium formate / palladium on carbon / isopropyl alcohol / 1 h / Inert atmosphere; Reflux
2: water; hydrogen bromide / methanol / 100 °C / 15 - 22.5 Torr
3: water; hydrogen bromide / 17 h / 105 °C
View Scheme
Multi-step reaction with 2 steps
1: ammonium formate / palladium on carbon / isopropyl alcohol / 1 h / Inert atmosphere; Reflux
2: water; hydrogen bromide / 5 h / 120 °C
View Scheme
Multi-step reaction with 2 steps
1: palladium on carbon / water; methanol / 5.75 h / 20 - 60 °C
2: water; hydrogen bromide / 17 h / 105 °C
View Scheme
3-(4-methoxyphenyl)-2-methyl-2-((S)-1-phenyl-ethylamino)-propionamide
1299492-11-7

3-(4-methoxyphenyl)-2-methyl-2-((S)-1-phenyl-ethylamino)-propionamide

L-methyltyrosine
672-87-7

L-methyltyrosine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: hydrogenchloride / isopropyl alcohol; water
2: hydrogen / palladium on carbon / methanol / 1.33 h / 50 °C / 2250.23 Torr
3: hydrogen bromide / water / 4 h / 120 °C
View Scheme
3-(4-methoxyphenyl)-2-methyl-2-((1S)-1-phenyl-ethylamino)-propionamide hydrochloride
1299492-12-8

3-(4-methoxyphenyl)-2-methyl-2-((1S)-1-phenyl-ethylamino)-propionamide hydrochloride

L-methyltyrosine
672-87-7

L-methyltyrosine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 2-methyl-propan-1-ol / Heating; Reflux
2: hydrogen / palladium on carbon / methanol / 1.33 h / 50 °C / 2250.23 Torr
3: hydrogen bromide / water / 4 h / 120 °C
View Scheme
(2S)-3-(4-methoxyphenyl)-2-methyl-2-((1S)-1-phenyl-ethylamino)-propionamide hydrochloride

(2S)-3-(4-methoxyphenyl)-2-methyl-2-((1S)-1-phenyl-ethylamino)-propionamide hydrochloride

L-methyltyrosine
672-87-7

L-methyltyrosine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: hydrogen / palladium on carbon / methanol / 1.33 h / 50 °C / 2250.23 Torr
2: hydrogen bromide / water / 4 h / 120 °C
View Scheme
C22H26ClNO3
1299492-17-3

C22H26ClNO3

L-methyltyrosine
672-87-7

L-methyltyrosine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: hydrogenchloride / isopropyl alcohol; water / 1 h / 20 °C
2: boron tribromide / dichloromethane / 1.5 h / 20 °C
View Scheme
2-amino-3-(4-hydroxy-phenyl)-2-methyl-propionic acid
658-48-0

2-amino-3-(4-hydroxy-phenyl)-2-methyl-propionic acid

A

L-methyltyrosine
672-87-7

L-methyltyrosine

B

α-methyl-D-tyrosine
672-86-6

α-methyl-D-tyrosine

Conditions
ConditionsYield
With Merck RP-18 WF254S plates coated with Nτ-n-decyl-L-spinacine and Cu acetate In ethanol; water Resolution of racemate;
N-(benzylidene)-O-methoxymethyl tyrosine tert-butyl ester

N-(benzylidene)-O-methoxymethyl tyrosine tert-butyl ester

methyl iodide
74-88-4

methyl iodide

L-methyltyrosine
672-87-7

L-methyltyrosine

Conditions
ConditionsYield
Stage #1: N-(benzylidene)-O-methoxymethyl tyrosine tert-butyl ester; methyl iodide With ((11bS)-(+)-4,4-dibutyl-4,5-dihydro-2,6-bis(3,4,5-triflourophenyl)-3H-dinaphth[2,1-c:1’,2’-e]azepinium bromide); cesium hydroxide In toluene at 0℃; for 0.5h; Inert atmosphere;
Stage #2: With hydrogenchloride In water; toluene at 60℃; for 0.5h; Inert atmosphere; stereoselective reaction;
n/a
(fluorenylmethoxy)carbonyl chloride
28920-43-6

(fluorenylmethoxy)carbonyl chloride

L-methyltyrosine
672-87-7

L-methyltyrosine

Fmoc-L-(α-Me)Tyr-OH
246539-83-3

Fmoc-L-(α-Me)Tyr-OH

Conditions
ConditionsYield
With sodium hydroxide In acetonitrile at 20℃; for 3h; Acylation;100%
methanol
67-56-1

methanol

L-methyltyrosine
672-87-7

L-methyltyrosine

(S)-2-amino-3-(4-hydroxy-phenyl)-2-methyl-propionic acid methyl ester hydrochloride

(S)-2-amino-3-(4-hydroxy-phenyl)-2-methyl-propionic acid methyl ester hydrochloride

Conditions
ConditionsYield
With thionyl chloride at 0 - 20℃; Heating / reflux;96%
With thionyl chloride at 0 - 20℃;
With thionyl chloride at 20℃; for 24h; Inert atmosphere; Reflux;1.48 g
L-methyltyrosine
672-87-7

L-methyltyrosine

n-hexadecanoyl chloride
112-67-4

n-hexadecanoyl chloride

N-palmitoyl-α-methyl-L-tyrosine

N-palmitoyl-α-methyl-L-tyrosine

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 20℃; for 16h;89%
In N,N-dimethyl-formamide at 20℃; for 16h;89%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

L-methyltyrosine
672-87-7

L-methyltyrosine

Boc-(L)(α-Me)Tyr-OH
74825-83-5

Boc-(L)(α-Me)Tyr-OH

Conditions
ConditionsYield
Stage #1: L-methyltyrosine With chloro-trimethyl-silane; N-ethyl-N,N-diisopropylamine In dichloromethane Inert atmosphere;
Stage #2: di-tert-butyl dicarbonate In dichloromethane Inert atmosphere;
Stage #3: With methanol for 0.5h; Inert atmosphere;
67%
With sodium hydroxide; sodium hydrogencarbonate In 1,4-dioxane at 20℃; pH=8 - 9;60%
With sodium hydroxide; tert-butyl alcohol35%
cis-dichloro(2,2′-bipyridine)ruthenium(II)chloride

cis-dichloro(2,2′-bipyridine)ruthenium(II)chloride

L-methyltyrosine
672-87-7

L-methyltyrosine

sodium perchlorate

sodium perchlorate

Ru(N2C10H8)2(NH2CCH3CH2C6H4OHCOO)(1+)*ClO4(1-)*2.5H2O=Ru(N2C10H8)2(NH2CCH3CH2C6H4OHCOO)ClO4*2.5H2O

Ru(N2C10H8)2(NH2CCH3CH2C6H4OHCOO)(1+)*ClO4(1-)*2.5H2O=Ru(N2C10H8)2(NH2CCH3CH2C6H4OHCOO)ClO4*2.5H2O

Conditions
ConditionsYield
With sodium hydroxide In ethanol; water Ru-complex was refluxed in mixt. of H2O and EtOH, to this soln. was added ligand followed by aq. NaOH, mixt. was heated at 70°C for 30 min, cooled to room temp., filtered, aq. soln. of NaClO4 was added, mixt.was stored in the dark for 48 h; solid was collected at the pump, washed with ice-cold H2O, dried in vac. over silica gel at room temp.; elem. anal.;41%
cis-dichloridobis(1,10-phenanthroline)ruthenium(II)

cis-dichloridobis(1,10-phenanthroline)ruthenium(II)

L-methyltyrosine
672-87-7

L-methyltyrosine

sodium perchlorate

sodium perchlorate

Ru(N2C12H8)2(NH2CCH3CH2C6H4OHCOO)(1+)*ClO4(1-)=Ru(N2C12H8)2(NH2CCH3CH2C6H4OHCOO)ClO4

Ru(N2C12H8)2(NH2CCH3CH2C6H4OHCOO)(1+)*ClO4(1-)=Ru(N2C12H8)2(NH2CCH3CH2C6H4OHCOO)ClO4

Conditions
ConditionsYield
With sodium hydroxide In ethanol; water Ru-complex was refluxed in mixt. of H2O and EtOH, to this soln. was added ligand followed by aq. NaOH, mixt. was heated at 70°C for 30 min, cooled to room temp., filtered, aq. soln. of NaClO4 was added, mixt.was stored in the dark for 48 h; solid was collected at the pump, washed with ice-cold H2O, dried in vac. over silica gel at room temp.; elem. anal.;39%
L-methyltyrosine
672-87-7

L-methyltyrosine

A

L-3-18F-α-methyltyrosine

L-3-18F-α-methyltyrosine

B

[18F]-3,5-difluoro-L-α-methyltyrosine

[18F]-3,5-difluoro-L-α-methyltyrosine

Conditions
ConditionsYield
With 18F-fluoride In formic acid at 4℃; Product distribution; Further Variations:; Solvents; Temperatures;A 13%
B 2%
With 18F-fluoride; hydrogen fluoride; boron trifluoride
L-methyltyrosine
672-87-7

L-methyltyrosine

3-iodo-α-methyl-L-tyrosine

3-iodo-α-methyl-L-tyrosine

Conditions
ConditionsYield
With ammonium hydroxide; iodine; potassium iodide
L-methyltyrosine
672-87-7

L-methyltyrosine

benzyl chloroformate
501-53-1

benzyl chloroformate

(S)-N2-<(benzyloxy)carbonyl>-2-methyltyrosine

(S)-N2-<(benzyloxy)carbonyl>-2-methyltyrosine

Conditions
ConditionsYield
With chloro-trimethyl-silane; N-ethyl-N,N-diisopropylamine 1.) CHCl3, 70 deg C, 1 h; 2.) CHCl3, 70 deg C, 1 h; 3.) CHCl3, 80 deg C, 17 h; Yield given. Multistep reaction;
L-methyltyrosine
672-87-7

L-methyltyrosine

L-3-18F-α-methyltyrosine

L-3-18F-α-methyltyrosine

Conditions
ConditionsYield
With 18F-fluoride; hydrogen fluoride
methanol
67-56-1

methanol

L-methyltyrosine
672-87-7

L-methyltyrosine

α-methyl-para-tyrosine methyl ester
7423-78-1

α-methyl-para-tyrosine methyl ester

Conditions
ConditionsYield
With thionyl chloride Heating;
L-methyltyrosine
672-87-7

L-methyltyrosine

Boc-(L)(α-Me)Tyr-OMe
675106-56-6

Boc-(L)(α-Me)Tyr-OMe

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: SOCl2 / Heating
2: aq. NaHCO3; NaOH / dioxane / 20 °C / pH 8 - 9
View Scheme
L-methyltyrosine
672-87-7

L-methyltyrosine

Boc-(L)(α-Me)Tyr(Tf)-OMe
675106-57-7

Boc-(L)(α-Me)Tyr(Tf)-OMe

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: SOCl2 / Heating
2: aq. NaHCO3; NaOH / dioxane / 20 °C / pH 8 - 9
3: 80 percent / Et3N / CH2Cl2 / 3 h / 20 °C
View Scheme
L-methyltyrosine
672-87-7

L-methyltyrosine

Boc-(L)(α-Me)Phe(4-PO3Et2)-OMe
675106-58-8

Boc-(L)(α-Me)Phe(4-PO3Et2)-OMe

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: SOCl2 / Heating
2: aq. NaHCO3; NaOH / dioxane / 20 °C / pH 8 - 9
3: 80 percent / Et3N / CH2Cl2 / 3 h / 20 °C
4: 77 percent / Pd(PPh3)4; N-methylmorpholine / acetonitrile / Heating
View Scheme
L-methyltyrosine
672-87-7

L-methyltyrosine

Boc-(α-Me)Tyr-Asn-NH2
675106-63-5

Boc-(α-Me)Tyr-Asn-NH2

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 60 percent / aq. NaHCO3; NaOH / dioxane / 20 °C / pH 8 - 9
2: 86 percent / DIEA; HOAt; HATU / dimethylformamide / 72 h / 20 °C
View Scheme
L-methyltyrosine
672-87-7

L-methyltyrosine

(L)(α-Me)Phe(4-PO3H2)-OH*HCl

(L)(α-Me)Phe(4-PO3H2)-OH*HCl

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: SOCl2 / Heating
2: aq. NaHCO3; NaOH / dioxane / 20 °C / pH 8 - 9
3: 80 percent / Et3N / CH2Cl2 / 3 h / 20 °C
4: 77 percent / Pd(PPh3)4; N-methylmorpholine / acetonitrile / Heating
5: 100 percent / aq. HCl / Heating
View Scheme
L-methyltyrosine
672-87-7

L-methyltyrosine

Boc-(α-Me)pTyr(Bzl2)-Asn-NH2
675106-65-7

Boc-(α-Me)pTyr(Bzl2)-Asn-NH2

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 60 percent / aq. NaHCO3; NaOH / dioxane / 20 °C / pH 8 - 9
2: 86 percent / DIEA; HOAt; HATU / dimethylformamide / 72 h / 20 °C
View Scheme
L-methyltyrosine
672-87-7

L-methyltyrosine

Boc-(α-Me)pTyr(MeSATE)2-Asn-NH2
675106-64-6

Boc-(α-Me)pTyr(MeSATE)2-Asn-NH2

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 60 percent / aq. NaHCO3; NaOH / dioxane / 20 °C / pH 8 - 9
2: 86 percent / DIEA; HOAt; HATU / dimethylformamide / 72 h / 20 °C
View Scheme
L-methyltyrosine
672-87-7

L-methyltyrosine

(α-Me)pTyr-Asn-NH2

(α-Me)pTyr-Asn-NH2

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 60 percent / aq. NaHCO3; NaOH / dioxane / 20 °C / pH 8 - 9
2: 86 percent / DIEA; HOAt; HATU / dimethylformamide / 72 h / 20 °C
3: 93 percent / CH2Cl2 / 3 h / 20 °C
View Scheme
L-methyltyrosine
672-87-7

L-methyltyrosine

(α-Me)pTyr(MeSATE)2-Asn-NH2

(α-Me)pTyr(MeSATE)2-Asn-NH2

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 60 percent / aq. NaHCO3; NaOH / dioxane / 20 °C / pH 8 - 9
2: 86 percent / DIEA; HOAt; HATU / dimethylformamide / 72 h / 20 °C
3: CH2Cl2 / 1 h / 0 °C
View Scheme

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