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Beijing Scrianen Pharmaceutical Co.,Ltd

Manufacturers, GMP products, long-term stable supply Application:It is used to treat acute leukemia and gastrointestinal cancer Port:Tianjin/Qingdao/Shanghai

Cytarabine Hydrochloride

Cas:69-74-9

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

1-beta-D-Arabinofuranosylcytosine hydrochloride

Cas:69-74-9

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Assay 99.9%min 99.9% Hangzhou Dingyan Chem is a leading manufacturer and supplier of che

High quality 69-74-9

Cas:69-74-9

Min.Order:1 Kilogram

FOB Price: $1300.0 / 1600.0

Type:Trading Company

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Cytarabine Hcl supplier in China

Cas:69-74-9

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Wuhan Fortuna Chemical Co.,Ltd

Unique advantages of 1-beta-D-Arabinofuranosylcytosine hydrochloride Cas 69-74-9 Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White or almost white crystalline powder St

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 1-β-D-arabinofuranosylcytosine hydrochloride

Cas:69-74-9

Min.Order:1

Negotiable

Type:Other

inquiry

Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need C

Cytarabine hydrochloride manufacturer with low price

Cas:69-74-9

Min.Order:1 Gram

Negotiable

Type:Manufacturers

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Cytarabine hydrochloride

Cas:69-74-9

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hubei DiBo chemical co., LTD

Name:cytosine arabinoside hydrochloride CAS NO:69-74-9 Grade:Medical scientific research and export Molecular formula:C9H14ClN3O5 Molecular weight:279.6776 Product Quality 12 years of chemical raw materials Mature operation of the industry

cytosine arabinoside hydrochloride/ CAS:69-74-9/raw material/ high-quality

Cas:69-74-9

Min.Order:25 Kilogram

FOB Price: $2.0 / 3.0

Type:Other

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

1-beta-D-Arabinofuranosylcytosine hydrochloride

Cas:69-74-9

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 69-74-9 with best quality

Cas:69-74-9

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages High purity, all above 98.5%, no impurities after dissolution We will test each batch to ensure quality OEM and private brand services designed for free Various cap colors available We can also provide MT1 peptide powd

1-beta-D-Arabinofuranosylcytosine hydrochlorideCAS69-74-9

Cas:69-74-9

Min.Order:1 Kilogram

FOB Price: $4.0 / 5.0

Type:Trading Company

inquiry

HANWAYS CHEMPHARM CO.,LIMITED

Hanways chempharm is a specialized company concentrating on the R&D, production, marketing and technical service of APIs and pharmaceutical intermediates. The marketing department is located in Wuhan. We have two GMP facilities in Hubei Pr

Anti-tumor API 99% Cytarabine hydrochloride CAS 69-74-9, Cytarabine HCL

Cas:69-74-9

Min.Order:1 Kilogram

FOB Price: $500.0 / 550.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1-beta-D-Arabinofuranosylcytosine hydrochloride 69-74-9

Cas:69-74-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Leader Biochemical Group

About Product Details Items Specifications Test Results Appearance White to white crystalline powde

Supply High Quality CYTARABINE HCL CAS 69-74-9 For research Use only

Cas:69-74-9

Min.Order:1 Gram

FOB Price: $1.0 / 2.0

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Cytarabine (hydrochloride)

Cas:69-74-9

Min.Order:1 Gram

FOB Price: $1489.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

1-beta-D-Arabinofuranosylcytosine hydrochloride CAS:69-74-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in

1-beta-D-Arabinofuranosylcytosine hydrochloride CAS:69-74-9

Cas:69-74-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Wonda Pharm Limited

1.high quality: quality is life. quality is the most important element for all goods. we have a lab doing research in wuhan china. hplc and nmr is available if needed. 2.reasonable price: we provide high quality products with competi

supply Cytarabine hydrochloride 69-74-9 with lower price Cytarabine price

Cas:69-74-9

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

cytosine arabinoside hydrochloride CAS 69-74-9

Cas:69-74-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

1-beta-D-Arabinofuranosylcytosine hydrochloride

Cas:69-74-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

1-beta-D-Arabinofuranosylcytosine hydrochloride

Cas:69-74-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Triumph International Development Limilted

Package:As customer request Application:Used for research and industrial manufacture. Transportation:By Sea/Air/Courier Port:Qingdao/Shanghai,China

cytosine arabinoside hydrochloride

Cas:69-74-9

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

1-beta-D-Arabinofuranosylcytosine hydrochloride

Cas:69-74-9

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

NewCan Biotech Limited

NewCan Biotech Limited was established in 2021 and is primarily engaged in the research, development, production, and sales of sugars, nucleosides, nucleotides, phosphorylated monomers, as well as next-generation antiviral and antitumor drug intermed

Cytarabine

Cas:69-74-9

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Cytosine-?-D-arabinofuranoside hydrochloride

Cas:69-74-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

1-beta-D-Arabinofuranosylcytosine hydrochloride

Cas:69-74-9

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

1-beta-D-Arabinofuranosylcytosine hydrochloride

Cas:69-74-9

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

1-beta-D-Arabinofuranosylcytosine hydrochloride 69-74-9

Cas:69-74-9

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

TaiChem Taizhou Limited

Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site

1-beta-D-Arabinofuranosylcytosine hydrochloride

Cas:69-74-9

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

arabinosyl cytosine
147-94-4

arabinosyl cytosine

cytarabine hydrochloride
69-74-9

cytarabine hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In methanol at 2 - 25℃; for 4h;96%
With hydrogenchloride In diethyl ether
ancitabine hydrochloride
10212-25-6

ancitabine hydrochloride

cytarabine hydrochloride
69-74-9

cytarabine hydrochloride

Conditions
ConditionsYield
With ammonia In water at 80℃; for 0.5h; Temperature;62.4%
cytarabine hydrochloride
69-74-9

cytarabine hydrochloride

3-Acryloylamino-propionic acid pentafluorophenyl ester
219797-98-5

3-Acryloylamino-propionic acid pentafluorophenyl ester

N-{2-[1-((2R,3S,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-2-oxo-1,2-dihydro-pyrimidin-4-ylcarbamoyl]-ethyl}-acrylamide
186594-89-8

N-{2-[1-((2R,3S,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-2-oxo-1,2-dihydro-pyrimidin-4-ylcarbamoyl]-ethyl}-acrylamide

Conditions
ConditionsYield
With 1,4-diaza-bicyclo[2.2.2]octane In pyridine at 80℃;95%
cytarabine hydrochloride
69-74-9

cytarabine hydrochloride

4-amino-5-chloro-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2(1H)-one
17676-65-2

4-amino-5-chloro-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2(1H)-one

Conditions
ConditionsYield
With hydrogenchloride; 3-chloro-benzenecarboperoxoic acid In N,N-dimethyl acetamide for 1h; Ambient temperature;83.9%
cytarabine hydrochloride
69-74-9

cytarabine hydrochloride

4-Acryloylamino-butyric acid pentafluorophenyl ester
219797-99-6

4-Acryloylamino-butyric acid pentafluorophenyl ester

N-(3-(N4-carbamoyl-1-(β-D-arabinofuranosyl)cytosine)-propyl)acrylamide
186594-93-4

N-(3-(N4-carbamoyl-1-(β-D-arabinofuranosyl)cytosine)-propyl)acrylamide

Conditions
ConditionsYield
With 1,4-diaza-bicyclo[2.2.2]octane In pyridine at 80℃;78%
cytarabine hydrochloride
69-74-9

cytarabine hydrochloride

elacytarabine

elacytarabine

Conditions
ConditionsYield
In ISOPROPYLAMIDE at 30℃; for 22h;72%
cytarabine hydrochloride
69-74-9

cytarabine hydrochloride

gondoic acid chloride

gondoic acid chloride

CP-4057

CP-4057

Conditions
ConditionsYield
In ISOPROPYLAMIDE; N,N-dimethyl-formamide at 25℃; for 24h;66%
N-(2-(4-chlorophenyl)-3-(2-(dipropylamino)-2-oxoethyl)imidazo[1,2-a]pyridin-8-yl)-6-oxo-6-(2-thioxothiazolidin-3-yl)hexanamide
1257411-82-7

N-(2-(4-chlorophenyl)-3-(2-(dipropylamino)-2-oxoethyl)imidazo[1,2-a]pyridin-8-yl)-6-oxo-6-(2-thioxothiazolidin-3-yl)hexanamide

cytarabine hydrochloride
69-74-9

cytarabine hydrochloride

N1-(2-(4-chlorophenyl)-3-(2-(dipropylamino)-2-oxoethyl)imidazo[1,2-a]pyridin-8-yl)-N6-(1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)adipamide
1257411-83-8

N1-(2-(4-chlorophenyl)-3-(2-(dipropylamino)-2-oxoethyl)imidazo[1,2-a]pyridin-8-yl)-N6-(1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)adipamide

Conditions
ConditionsYield
With pyridine at 50℃;66%
cytarabine hydrochloride
69-74-9

cytarabine hydrochloride

2-(6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)acetic acid
82626-74-2

2-(6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)acetic acid

2-(6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)-N-(1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide
1257411-86-1

2-(6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)-N-(1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide

Conditions
ConditionsYield
Stage #1: 2-(6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)acetic acid With 1,1'-carbonyldiimidazole In N,N-dimethyl-formamide at 20℃; for 0.25h; Inert atmosphere;
Stage #2: cytarabine hydrochloride In N,N-dimethyl-formamide Inert atmosphere;
65%
2-(pyridin-2-yldisulfaneyl)ethyl 1H-1,2,4-triazole-1-carboxylate

2-(pyridin-2-yldisulfaneyl)ethyl 1H-1,2,4-triazole-1-carboxylate

cytarabine hydrochloride
69-74-9

cytarabine hydrochloride

2-(pyridin-2-yldisulfaneyl)ethyl (1-((3S,4S)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)carbamate

2-(pyridin-2-yldisulfaneyl)ethyl (1-((3S,4S)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)carbamate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 2h;63%
mono (2,2,2-trichloroethyl) azelaoyl chloride

mono (2,2,2-trichloroethyl) azelaoyl chloride

cytarabine hydrochloride
69-74-9

cytarabine hydrochloride

5'-O-[(2,2,2-trichloroethyl)-azelaoyl]-1-β-D-arabinofuranosyl-cytosine
879015-37-9

5'-O-[(2,2,2-trichloroethyl)-azelaoyl]-1-β-D-arabinofuranosyl-cytosine

Conditions
ConditionsYield
In DMA at 20℃;56.7%
cytarabine hydrochloride
69-74-9

cytarabine hydrochloride

Hexanoyl chloride
142-61-0

Hexanoyl chloride

C15H23N3O6

C15H23N3O6

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 20℃; for 24h;55%
cytarabine hydrochloride
69-74-9

cytarabine hydrochloride

n-octanoic acid chloride
111-64-8

n-octanoic acid chloride

4-amino-1-(O5-octanoyl-β-D-arabinofuranosyl)-1H-pyrimidin-2-one
31088-08-1

4-amino-1-(O5-octanoyl-β-D-arabinofuranosyl)-1H-pyrimidin-2-one

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 20℃; for 24h;55%
cytarabine hydrochloride
69-74-9

cytarabine hydrochloride

(4S)-5'-O-cis-[4-(pyridin-4yl)-2-oxido-1,3,2-dioxaphosphorinan-2yl]-cytosine-β-D-arabinofuranoside
685111-92-6

(4S)-5'-O-cis-[4-(pyridin-4yl)-2-oxido-1,3,2-dioxaphosphorinan-2yl]-cytosine-β-D-arabinofuranoside

Conditions
ConditionsYield
Stage #1: (-)-(S)-1-(pyridin-4-yl)-1,3-propanediol With 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; trichlorophosphate In pyridine; acetonitrile at -17 - 42℃; for 3.6h;
Stage #2: cytarabine hydrochloride In pyridine; acetonitrile at 4 - 6℃; for 88h;
48%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

cytarabine hydrochloride
69-74-9

cytarabine hydrochloride

A

tert-butyl 1-((2R,3S,4R,5R)-3,4-bis(tert-butoxycarbonyloxy)-5-((tert-butoxycarbonyloxy)-methyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-ylcarbamate

tert-butyl 1-((2R,3S,4R,5R)-3,4-bis(tert-butoxycarbonyloxy)-5-((tert-butoxycarbonyloxy)-methyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-ylcarbamate

B

C24H37N3O11
1257411-75-8

C24H37N3O11

Conditions
ConditionsYield
With potassium hydroxide In 1,4-dioxane; water at 20℃; for 17h;A 15%
B 48%
cytarabine hydrochloride
69-74-9

cytarabine hydrochloride

butyryl chloride
141-75-3

butyryl chloride

C13H19N3O6
917898-23-8

C13H19N3O6

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 20℃; for 24h;42%
propionyl chloride
79-03-8

propionyl chloride

cytarabine hydrochloride
69-74-9

cytarabine hydrochloride

5'-O-propionyl ara-C
881848-60-8

5'-O-propionyl ara-C

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 20℃; for 24h;39%
cytarabine hydrochloride
69-74-9

cytarabine hydrochloride

n-decanoyl chloride
112-13-0

n-decanoyl chloride

4-amino-1-(O5-decanoyl-β-D-arabinofuranosyl)-1H-pyrimidin-2-one
58611-44-2

4-amino-1-(O5-decanoyl-β-D-arabinofuranosyl)-1H-pyrimidin-2-one

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 20℃; for 24h;31%
cytarabine hydrochloride
69-74-9

cytarabine hydrochloride

acetyl chloride
75-36-5

acetyl chloride

4-amino-1-(O5-acetyl-β-D-arabinofuranosyl)-1H-pyrimidin-2-one
31088-09-2

4-amino-1-(O5-acetyl-β-D-arabinofuranosyl)-1H-pyrimidin-2-one

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 20℃; for 24h;27%
(4S)-(-)-trans-(4-pyridyl)-2-chloro-2-oxo-1,3,2-dioxaphosphorinane

(4S)-(-)-trans-(4-pyridyl)-2-chloro-2-oxo-1,3,2-dioxaphosphorinane

cytarabine hydrochloride
69-74-9

cytarabine hydrochloride

(4S)-5'-O-cis-[4-(pyridin-4yl)-2-oxido-1,3,2-dioxaphosphorinan-2yl]-cytosine-β-D-arabinofuranoside
685111-92-6

(4S)-5'-O-cis-[4-(pyridin-4yl)-2-oxido-1,3,2-dioxaphosphorinan-2yl]-cytosine-β-D-arabinofuranoside

Conditions
ConditionsYield
Stage #1: (4S)-(-)-trans-(4-pyridyl)-2-chloro-2-oxo-1,3,2-dioxaphosphorinane; cytarabine hydrochloride With 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone In acetonitrile at 20 - 35℃; for 48h;
Stage #2: With methanol In acetonitrile at 20℃; for 2h;
26%
cytarabine hydrochloride
69-74-9

cytarabine hydrochloride

[2-(4-chlorophenyl)-6,8-dichloroimidazo[1,2-a]pyridin-3-yl]acetic acid
362512-44-5

[2-(4-chlorophenyl)-6,8-dichloroimidazo[1,2-a]pyridin-3-yl]acetic acid

2-(6,8-dichloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)-N-(1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide
1257411-84-9

2-(6,8-dichloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)-N-(1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide

Conditions
ConditionsYield
Stage #1: [2-(4-chlorophenyl)-6,8-dichloroimidazo[1,2-a]pyridin-3-yl]acetic acid With 1,1'-carbonyldiimidazole In N,N-dimethyl-formamide at 20℃; for 0.25h; Inert atmosphere;
Stage #2: cytarabine hydrochloride In N,N-dimethyl-formamide Inert atmosphere;
25%
cytarabine hydrochloride
69-74-9

cytarabine hydrochloride

(6,8-Dichloro-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-acetic acid
573704-25-3

(6,8-Dichloro-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-acetic acid

2-(6,8-dichloro-2-(phenyl)imidazo[1,2-a]pyridin-3-yl)-N-(1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide
1257411-85-0

2-(6,8-dichloro-2-(phenyl)imidazo[1,2-a]pyridin-3-yl)-N-(1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide

Conditions
ConditionsYield
Stage #1: (6,8-Dichloro-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-acetic acid With 1,1'-carbonyldiimidazole In N,N-dimethyl-formamide at 20℃; for 0.25h; Inert atmosphere;
Stage #2: cytarabine hydrochloride In N,N-dimethyl-formamide Inert atmosphere;
23%
methyl 9-chloro-9-oxononanoate
56555-02-3

methyl 9-chloro-9-oxononanoate

cytarabine hydrochloride
69-74-9

cytarabine hydrochloride

1-(5-O-azelayl-β-D-arabinofuranosyl)cytosine methyl ester
848046-38-8

1-(5-O-azelayl-β-D-arabinofuranosyl)cytosine methyl ester

Conditions
ConditionsYield
Stage #1: methyl 9-chloro-9-oxononanoate; cytarabine hydrochloride In 2,4-dichlorophenoxyacetic acid dimethylamine at 20℃;
Stage #2: With triethylamine
21.6%
cytarabine hydrochloride
69-74-9

cytarabine hydrochloride

benzyl chloroformate
501-53-1

benzyl chloroformate

benzyl 1-(3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-ylcarbamate
170935-63-4

benzyl 1-(3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-ylcarbamate

Conditions
ConditionsYield
With potassium hydrogencarbonate In water; ethyl acetate at 80℃; for 16h;15%
acetic anhydride
108-24-7

acetic anhydride

cytarabine hydrochloride
69-74-9

cytarabine hydrochloride

N4-acetyl-1-<2',3',5'-tri-O-acetyl-β-D-arabinofuranosyl>cytosine
6742-08-1

N4-acetyl-1-<2',3',5'-tri-O-acetyl-β-D-arabinofuranosyl>cytosine

Conditions
ConditionsYield
With pyridine at 45℃; for 18h;129 g
chloro-trimethyl-silane
75-77-4

chloro-trimethyl-silane

cytarabine hydrochloride
69-74-9

cytarabine hydrochloride

4-Amino-1-((2R,3S,4R,5R)-3,4-bis-trimethylsilanyloxy-5-trimethylsilanyloxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidin-2-one
51432-43-0

4-Amino-1-((2R,3S,4R,5R)-3,4-bis-trimethylsilanyloxy-5-trimethylsilanyloxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidin-2-one

Conditions
ConditionsYield
With pyridine at 20℃; for 1h;
cytarabine hydrochloride
69-74-9

cytarabine hydrochloride

1-(β-D-arabinofuranosyl)-N4-benzoylcytosine
16640-05-4

1-(β-D-arabinofuranosyl)-N4-benzoylcytosine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: pyridine / 1 h / 20 °C
2: pyridine / 4 h / 20 °C
3: aq. NH4OH / 0.25 h / 20 °C
View Scheme
cytarabine hydrochloride
69-74-9

cytarabine hydrochloride

N-[1-((2R,3S,4R,5R)-3,4-Bis-trimethylsilanyloxy-5-trimethylsilanyloxymethyl-tetrahydro-furan-2-yl)-2-oxo-1,2-dihydro-pyrimidin-4-yl]-benzamide

N-[1-((2R,3S,4R,5R)-3,4-Bis-trimethylsilanyloxy-5-trimethylsilanyloxymethyl-tetrahydro-furan-2-yl)-2-oxo-1,2-dihydro-pyrimidin-4-yl]-benzamide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: pyridine / 1 h / 20 °C
2: pyridine / 4 h / 20 °C
View Scheme
cytarabine hydrochloride
69-74-9

cytarabine hydrochloride

1-(2,3,5-tri-O-acetyl-β-D-arabinofuranosyl)cytosine
6742-07-0

1-(2,3,5-tri-O-acetyl-β-D-arabinofuranosyl)cytosine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 129 g / pyridine / 18 h / 45 °C
2: ZnBr2 / CHCl3; methanol / Ambient temperature
View Scheme

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