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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

5-Bromothiophene-2-carboxylic acid

Cas:7311-63-9

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 5-Bromo-2-Thiophenecarboxylic Acid supplier in China

Cas:7311-63-9

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, intermedi

5-Bromothiophene-2-carboxylic acid

Cas:7311-63-9

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

5-Bromo-2-thiophenecarboxylic acid

Cas:7311-63-9

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Jinan Finer Chemical Co., Ltd

Product Description Product website: http://www.finerchem.com Product Name 5-Bromothiophene-2-carboxylic acid CAS No. 7311-63-9

5-Bromothiophene-2-carboxylic acid

Cas:7311-63-9

Min.Order:1 Gram

FOB Price: $12.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

5-Bromo-2-thiophenecarboxylic acid

Cas:7311-63-9

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 7311-63-9 with best quality

Cas:7311-63-9

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

5-Bromothiophene-2-carboxylic acid 7311-63-9

Cas:7311-63-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:7311-63-9

Cas:7311-63-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

5-Bromo-2-thiophenecarboxylic acid

Cas:7311-63-9

Min.Order:1 Kilogram

FOB Price: $10.0 / 30.0

Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

5-Bromo-2-Thiophenecarboxylic Acid

Cas:7311-63-9

Min.Order:0

Negotiable

Type:Manufacturers

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

5-Bromothiophene-2-carboxylic acid

Cas:7311-63-9

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

5-BROMOTHIOPHENE-2-CARBOXYLIC ACID

Cas:7311-63-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 5-Bromothiophene-2-carboxylic acid

Cas:7311-63-9

Min.Order:0 Metric Ton

Negotiable

Type:Other

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

5-Bromothiophene-2-carboxylic acid

Cas:7311-63-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: 5-Bromothiophene-2-Carboxylic Acid CAS No.:7311-63-9 Molecule Formula:C5H3BrO2S Molecule Weight:207.05 Purity: 99.0% Package: 25kg/drum Description:White crystalline powder Manufacture Standards:Enterprise Standard

Best Quality 5-Bromothiophene-2-Carboxylic Acid with good supplier

Cas:7311-63-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

5-Bromo-2-thiophenecarboxylic acid,7311-63-9

Cas:7311-63-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

5-Bromo-2-thiophenecarboxylic acid Basic information Product Name: 5-Bromo-2-thiophenecarboxylic acid Synonyms: 5-BROMOTHIOPHENE-2-CARBOXYLIC ACID;AKOS 92445;5-BROMO-2-THIOPHENECARBOXYLIC ACID;BUTTPARK 97\04-65;RARECHEM AL BO 1503;OTAVA-BB BB7

5-Bromo-2-thiophenecarboxylic acid

Cas:7311-63-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

5-Bromothiophene-2-carboxylic acid

Cas:7311-63-9

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

5-Bromo-2-thiophenecarboxylic acid

Cas:7311-63-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

5-Bromothiophene-2-carboxylic acid

Cas:7311-63-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

5-Bromothiophene-2-carboxylic acid

Cas:7311-63-9

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

5-Bromothiophene-2-carboxylic acid

Cas:7311-63-9

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

SAGECHEM LIMITED

SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in custom synthe

SAGECHEM/5-Bromo-2-thiophenecarboxylic acid

Cas:7311-63-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

5-Bromothiophene-2-carboxylic acid

Cas:7311-63-9

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

5-Bromothiophene-2-Carboxylic Acid cas no. 7311-63-9 98%

Cas:7311-63-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,Pharmaceutical intermediates Transportation:air,sea,courier

5-Bromothiophene-2-carboxylic acid

Cas:7311-63-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

JINHUA HUAYI CHEMICAL CO., LTD.

Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

5-Bromothiophene-2-Carboxylic Acid

Cas:7311-63-9

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

5-Bromo-2-thiophenecarboxylic acid

Cas:7311-63-9

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

5-Bromo-2-Thiophenecarboxylic Acid

Cas:7311-63-9

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Synthetic route

5-bromo-2-thiophencarboxaldehyde
4701-17-1

5-bromo-2-thiophencarboxaldehyde

5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

Conditions
ConditionsYield
With chromium(III) oxide; sulfuric acid In acetone at 5 - 20℃; for 2.5h;99%
With potassium permanganate In acetone at 0 - 20℃; for 3h;85%
With potassium permanganate
5-((trimethylsilyl)ethynyl)thiophene-2-carbaldehyde
206768-50-5

5-((trimethylsilyl)ethynyl)thiophene-2-carbaldehyde

5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

Conditions
ConditionsYield
With Jones reagent In acetone at 5 - 20℃; for 2.5h; Inert atmosphere;99%
2,5-dibromothiophen
3141-27-3

2,5-dibromothiophen

carbon dioxide
124-38-9

carbon dioxide

5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

Conditions
ConditionsYield
With magnesium In tetrahydrofuran at -78℃; for 0.5h;88%
2-bromothiophene
1003-09-4

2-bromothiophene

carbon dioxide
124-38-9

carbon dioxide

5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

Conditions
ConditionsYield
Stage #1: 2-bromothiophene With lithium diisopropyl amide at -40℃;
Stage #2: carbon dioxide at -78℃;
85%
2-thiophenylcarboxylic acid
527-72-0

2-thiophenylcarboxylic acid

5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

Conditions
ConditionsYield
With bromine; acetic acid at 0℃;47%
With N-Bromosuccinimide In N,N-dimethyl-formamide at 75℃; for 12h; Inert atmosphere; Schlenk technique;35%
With bromine; acetic acid
With bromine In acetic acid at 20℃; for 16h;
With bromine
2,5-dibromothiophen
3141-27-3

2,5-dibromothiophen

carbon dioxide
124-38-9

carbon dioxide

A

5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

B

Thiophene-2,5-dicarboxylic acid
4282-31-9

Thiophene-2,5-dicarboxylic acid

Conditions
ConditionsYield
Stage #1: 2,5-dibromothiophen; carbon dioxide With tert.-butyl lithium In pentane at -70℃; Inert atmosphere;
Stage #2: With sulfuric acid; water In pentane at 20℃; Inert atmosphere;
A 34%
B 5%
2-bromothiophene
1003-09-4

2-bromothiophene

5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

Conditions
ConditionsYield
With palladium diacetate; sodium persulfate In acetic acid for 7h; Heating;23.6%
With diethyl ether; sodium Behandeln des Reaktionsgemisches mit festem Kohlendioxid;
2-bromothiophene
1003-09-4

2-bromothiophene

carbon dioxide
124-38-9

carbon dioxide

A

2-thiophenylcarboxylic acid
527-72-0

2-thiophenylcarboxylic acid

B

5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

Conditions
ConditionsYield
With ethylaluminum dichloride In hexane; chlorobenzene at 100℃; under 22502.3 Torr; for 3h; Autoclave; Inert atmosphere; regioselective reaction;A 6%
B 10%
2-bromothiophene
1003-09-4

2-bromothiophene

A

2-thiophenylcarboxylic acid
527-72-0

2-thiophenylcarboxylic acid

B

5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

Conditions
ConditionsYield
With sodium persulfate; sodium acetate; palladium In acetic acid at 70 - 80℃; for 7h;A 4.4%
B 8.8%
2,5-dibromothiophen
3141-27-3

2,5-dibromothiophen

5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

Conditions
ConditionsYield
With diethyl ether; ethylmagnesium bromide Behandeln der Reaktionsloesung mit Kohlendioxid;
With methyl bromide; diethyl ether; magnesium Behandeln der Reaktionsloesung mit Kohlendioxid;
With n-butyllithium In tetrahydrofuran; hydrogenchloride liquid HCl;
2-Acetyl-5-bromothiophene
5370-25-2

2-Acetyl-5-bromothiophene

5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

Conditions
ConditionsYield
With sodium hydroxide; potassium permanganate; water
With alkaline aqueous sodium hypochlorite solution
With 1,4-dioxane; alkaline aqueous sodium hypobromite solution
With bromine; sodium hydroxide In 1,4-dioxane
5-bromo-[2]thienyl sodium

5-bromo-[2]thienyl sodium

diethyl ether
60-29-7

diethyl ether

carbon dioxide
124-38-9

carbon dioxide

5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

2,5-dibromothiophen
3141-27-3

2,5-dibromothiophen

ethyl bromide
74-96-4

ethyl bromide

diethyl ether
60-29-7

diethyl ether

methylammonium carbonate
15719-64-9, 15719-76-3, 97762-63-5

methylammonium carbonate

magnesium

magnesium

5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

N,N'-bis-(5-bromo-thiophene-2-carbonyl)-o-phenylenediamine
859489-42-2

N,N'-bis-(5-bromo-thiophene-2-carbonyl)-o-phenylenediamine

A

5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

B

2-<5-bromo-<2>thienyl>-benzimidazole

2-<5-bromo-<2>thienyl>-benzimidazole

Conditions
ConditionsYield
Erhitzen auf Temperaturen oberhalb des Schmelzpunktes;
ethyl 5-bromothiophene-2-carboxylate
5751-83-7

ethyl 5-bromothiophene-2-carboxylate

5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

Conditions
ConditionsYield
With potassium hydroxide In ethanol Heating;
(5-bromothien-2-yl)methanol
79387-71-6

(5-bromothien-2-yl)methanol

5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

Conditions
ConditionsYield
With 3,5-Lutidine; 4-acetylamino-2,2,6,6-tetramethylpiperidine-N-oxyl; sodium persulfate; tris(2,2'‐bipyridine)ruthenium(II) hexafluorophosphate In water; acetonitrile at 20℃; for 48h; Sealed tube; Irradiation;15 %Chromat.
methanol
67-56-1

methanol

5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

5-bromo-2-thiophenecarboxylic acid methyl ester
62224-19-5

5-bromo-2-thiophenecarboxylic acid methyl ester

Conditions
ConditionsYield
With sulfuric acid for 12h; Heating;100%
With thionyl chloride for 3h;100%
With sulfuric acid for 30h; Reflux;96%
5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

5-bromo-2-thiophenecarboxylic acid methyl ester
62224-19-5

5-bromo-2-thiophenecarboxylic acid methyl ester

Conditions
ConditionsYield
In acetic acid100%
Multi-step reaction with 2 steps
1: SOCl2 / 0.25 h / Heating
2: 1 h / Heating
View Scheme
In acetic acid
With sulfuric acid In methanol; ethyl acetate
5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

1-(phenylsulfonyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo-[2,3-b]pyridine
942919-24-6

1-(phenylsulfonyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo-[2,3-b]pyridine

5-[1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]2-thiophenecarboxylic acid
943321-66-2

5-[1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]2-thiophenecarboxylic acid

Conditions
ConditionsYield
With potassium carbonate; tetrakis(triphenylphosphine) palladium(0) In 1,4-dioxane; water at 80℃; for 12h; Suzuki Coupling;100%
5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

5-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)-1-methyl-1H-pyrazole
1044851-76-4

5-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)-1-methyl-1H-pyrazole

5-(1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxylic acid
656226-60-7

5-(1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxylic acid

Conditions
ConditionsYield
With potassium carbonate; tetrakis(triphenylphosphine) palladium(0) In 1,4-dioxane; water at 80℃; for 12h;100%
1-methyl-piperazine
109-01-3

1-methyl-piperazine

5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

C10H13BrN2OS

C10H13BrN2OS

Conditions
ConditionsYield
Stage #1: 5-bromothiophene-2-carboxylic acid With thionyl chloride In dichloromethane; N,N-dimethyl-formamide for 3h; Reflux;
Stage #2: With potassium carbonate In dichloromethane at 0 - 10℃; for 0.333333h;
Stage #3: 1-methyl-piperazine In dichloromethane at 20℃; for 2h;
100%
5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

5-bromothiophene-2-carbonyl chloride
31555-60-9

5-bromothiophene-2-carbonyl chloride

Conditions
ConditionsYield
With thionyl chloride; N,N-dimethyl-formamide In chloroform for 1h; Heating / reflux;99%
With thionyl chloride
With thionyl chloride for 0.25h; Heating;
5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

allyl bromide
106-95-6

allyl bromide

5-allylthiophene-2-carboxylic acid
77756-24-2

5-allylthiophene-2-carboxylic acid

Conditions
ConditionsYield
Stage #1: 5-bromothiophene-2-carboxylic acid; allyl bromide With isopropylmagnesium bromide In tetrahydrofuran at -40℃; for 3h; Solid phase reaction;
Stage #2: In dichloromethane at 20℃; for 0.25h; Hydrolysis; Further stages.;
99%
5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

diazomethyl-trimethyl-silane
18107-18-1

diazomethyl-trimethyl-silane

5-bromo-2-thiophenecarboxylic acid methyl ester
62224-19-5

5-bromo-2-thiophenecarboxylic acid methyl ester

Conditions
ConditionsYield
In methanol; diethyl ether; ethyl acetate at 20℃; Cooling with ice;98%
In methanol; diethyl ether; ethyl acetate for 24.33h; Cooling with ice;98%
In methanol; diethyl ether; ethyl acetate at 20℃; Temperature; Time; Cooling with ice;98%
In methanol; diethyl ether; ethyl acetate for 24h;98%
5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

benzyl bromide
100-39-0

benzyl bromide

benzyl 5-bromothiophene-2-carboxylate

benzyl 5-bromothiophene-2-carboxylate

Conditions
ConditionsYield
Stage #1: 5-bromothiophene-2-carboxylic acid With tetra-(n-butyl)ammonium iodide; caesium carbonate In N,N-dimethyl-formamide at 20℃; for 0.166667h;
Stage #2: benzyl bromide In N,N-dimethyl-formamide at 20℃; for 20h;
98%
5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

(3‐cyanophenyl)boronic acid
150255-96-2

(3‐cyanophenyl)boronic acid

5-(3-cyanophenyl)thiophene-2-carboxylic acid
253679-30-0

5-(3-cyanophenyl)thiophene-2-carboxylic acid

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In ethanol; water for 12h; Inert atmosphere; Reflux;98%
5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

2-octyldodecan-1-ol
5333-42-6

2-octyldodecan-1-ol

2-octyl-dodecyl 5-bromothiophene-2-carboxylate
808142-41-8

2-octyl-dodecyl 5-bromothiophene-2-carboxylate

Conditions
ConditionsYield
With 4-(dimethylamino)pyridinium tosylate; diisopropyl-carbodiimide In dichloromethane at 20℃;97%
5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

4-(2-keto-1-benzimidazolinyl)piperidine
20662-53-7

4-(2-keto-1-benzimidazolinyl)piperidine

C17H16BrN3O2S

C17H16BrN3O2S

Conditions
ConditionsYield
With pyridine; 1,3,5-trichloro-2,4,6-triazine In acetonitrile at 140℃; for 0.0833333h; Microwave irradiation;97%
5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

phenylboronic acid
98-80-6

phenylboronic acid

5-phenyl-2-thiophenecarboxylic acid
19163-24-7

5-phenyl-2-thiophenecarboxylic acid

Conditions
ConditionsYield
With disodium hydrogenphosphate; Pd(OAc)2(2-amino-4,6-dihydroxypyrimidine disodium salt)2 In water at 120℃; for 0.166667h; Suzuki-Miyaura coupling; Microwave irradiation;96%
With 1-methyl-pyrrolidin-2-one; tetrakis(triphenylphosphine) palladium(0); sodium carbonate Suzuki coupling; Heating;
5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

(2S)-2-methyl-1-butanol
1565-80-6

(2S)-2-methyl-1-butanol

(S)-2-methylbuthyl-5-bromothyophene-2-carboxylate

(S)-2-methylbuthyl-5-bromothyophene-2-carboxylate

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In chloroform for 72h; Inert atmosphere;95.8%
5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

propionyl chloride
79-03-8

propionyl chloride

5-propanoylthiophene-2-carboxylic acid
4565-27-9

5-propanoylthiophene-2-carboxylic acid

Conditions
ConditionsYield
Stage #1: 5-bromothiophene-2-carboxylic acid; propionyl chloride With isopropylmagnesium bromide In tetrahydrofuran at -40 - -10℃; for 12h; Solid phase reaction;
Stage #2: In dichloromethane at 20℃; for 0.25h; Hydrolysis; Further stages.;
95%
5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

furan-3-boronic acid
55552-70-0

furan-3-boronic acid

5-furan-3-ylthiophene-2-carboxylic acid

5-furan-3-ylthiophene-2-carboxylic acid

Conditions
ConditionsYield
With sodium 2'‐(dicyclohexylphosphaneyl)‐2,6‐diisopropyl‐[1,1'‐biphenyl]‐3‐sulfonate; palladium diacetate; potassium carbonate In water at 150℃; for 0.166667h; Suzuki-Miyaura coupling; microwave irradiation;95%
5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

4-Iodo-N,N-dimethylaniline
698-70-4

4-Iodo-N,N-dimethylaniline

5-[4-(dimethylamino)phenyl]thiophene-2-carboxylic acid

5-[4-(dimethylamino)phenyl]thiophene-2-carboxylic acid

Conditions
ConditionsYield
Multistep reaction.;95%
5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

benzoic acid hydrazide
613-94-5

benzoic acid hydrazide

2-(5-bromo-thiophen-2-yl)-5-phenyl-[1,3,4]oxadiazole
35403-81-7

2-(5-bromo-thiophen-2-yl)-5-phenyl-[1,3,4]oxadiazole

Conditions
ConditionsYield
Stage #1: 5-bromothiophene-2-carboxylic acid; benzoic acid hydrazide With N-ethyl-N,N-diisopropylamine; HATU In tetrahydrofuran at 20℃; for 0.75h;
Stage #2: With Burgess Reagent In tetrahydrofuran at 20℃;
95%
5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

P-toluenesulfonyl cyanide
19158-51-1

P-toluenesulfonyl cyanide

5-cyanothiophene-2-carboxylic acid
59786-39-9

5-cyanothiophene-2-carboxylic acid

Conditions
ConditionsYield
Stage #1: 5-bromothiophene-2-carboxylic acid; P-toluenesulfonyl cyanide With isopropylmagnesium bromide In tetrahydrofuran at -40℃; for 2h; Solid phase reaction;
Stage #2: In dichloromethane at 20℃; for 0.25h; Hydrolysis; Further stages.;
93%
5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

benzoyl chloride
98-88-4

benzoyl chloride

5-(Phenylcarbonyl)thiophene-2-carboxylic acid
79505-01-4

5-(Phenylcarbonyl)thiophene-2-carboxylic acid

Conditions
ConditionsYield
Stage #1: 5-bromothiophene-2-carboxylic acid; benzoyl chloride With isopropylmagnesium bromide In tetrahydrofuran at -40 - -10℃; for 12h; Solid phase reaction;
Stage #2: In dichloromethane at 20℃; for 0.25h; Hydrolysis; Further stages.;
93%
5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

methanethiosulfonic acid S-methyl ester
2949-92-0

methanethiosulfonic acid S-methyl ester

5-methylsulfanyl-thiophene-2-carboxylic acid
20873-58-9

5-methylsulfanyl-thiophene-2-carboxylic acid

Conditions
ConditionsYield
Stage #1: 5-bromothiophene-2-carboxylic acid With methylmagnesium chloride; lithium chloride In tetrahydrofuran at -20℃; for 0.333333h;
Stage #2: With TurboGrignard In tetrahydrofuran at 20℃; for 0.5h;
Stage #3: methanethiosulfonic acid S-methyl ester In tetrahydrofuran at -20 - 20℃; Further stages.;
93%
5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

N-[2-amino-1-(3-amino-3-oxopropyl)-1H-benzimidazol-5-yl]-N-methylbenzamide
658700-12-0

N-[2-amino-1-(3-amino-3-oxopropyl)-1H-benzimidazol-5-yl]-N-methylbenzamide

C23H20BrN5O3S
1092486-06-0

C23H20BrN5O3S

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃;93%
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 24h;
5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

5-bromo-thiophene-2-carboxylic acid hydrazide
98027-27-1

5-bromo-thiophene-2-carboxylic acid hydrazide

Conditions
ConditionsYield
Stage #1: 5-bromothiophene-2-carboxylic acid With dicyclohexyl-carbodiimide In acetonitrile at 0 - 20℃;
Stage #2: With benzotriazol-1-ol In acetonitrile at 0 - 20℃;
Stage #3: With hydrazine hydrate In acetonitrile at 0 - 20℃; for 5h;
93%
5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

1-amino-2-propene
107-11-9

1-amino-2-propene

C8H8BrNOS

C8H8BrNOS

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In tetrahydrofuran at 20℃;93%
With dmap; dicyclohexyl-carbodiimide In tetrahydrofuran at 20℃;93%
With dmap; dicyclohexyl-carbodiimide In tetrahydrofuran at 20℃;93%
5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

monomethyl monopotassium malonate
38330-80-2

monomethyl monopotassium malonate

methyl 3-(5-bromothiophen-2-yl)-3-oxopropionate
137090-42-7

methyl 3-(5-bromothiophen-2-yl)-3-oxopropionate

Conditions
ConditionsYield
Stage #1: 5-bromothiophene-2-carboxylic acid With 1,1'-carbonyldiimidazole In acetonitrile at 20℃;
Stage #2: monomethyl monopotassium malonate With magnesium chloride at 20℃; for 18h;
92.3%
5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

ethyl 2-bromomethyl-2-propenoate
17435-72-2

ethyl 2-bromomethyl-2-propenoate

5-[2-(ethoxycarbonyl)allyl]thiophene-2-carboxylic acid

5-[2-(ethoxycarbonyl)allyl]thiophene-2-carboxylic acid

Conditions
ConditionsYield
Stage #1: 5-bromothiophene-2-carboxylic acid; ethyl 2-bromomethyl-2-propenoate With isopropylmagnesium bromide In tetrahydrofuran at -40℃; for 3h; Solid phase reaction;
Stage #2: In dichloromethane at 20℃; for 0.25h; Hydrolysis; Further stages.;
92%
5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

4-methylphenylboronic acid
5720-05-8

4-methylphenylboronic acid

5-(4-methylphenyl)thiophene-2-carboxylic acid
40808-21-7

5-(4-methylphenyl)thiophene-2-carboxylic acid

Conditions
ConditionsYield
Stage #1: 5-bromothiophene-2-carboxylic acid; 4-methylphenylboronic acid; palladium diacetate In water at 20℃; for 0.0833333h; Suzuki-Miyaura coupling;
Stage #2: With potassium hydroxide In water at 20 - 75℃; for 3h;
92%
5-bromothiophene-2-carboxylic acid
7311-63-9

5-bromothiophene-2-carboxylic acid

2,5-dibromothiophen
3141-27-3

2,5-dibromothiophen

Conditions
ConditionsYield
With potassium phosphate; tetrabuthylammonium tribromide In acetonitrile at 100℃;92%

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