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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

2-Amino-4-chlorophenol-6-sulfonic acid

Cas:88-23-3

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Content 99.0%min 99.1% Appearance White powder White powd

High purity 3-amino-5-chloro-2-hydroxybenzenesulfonic acid CAS:88-23-3

Cas:88-23-3

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Manufacturers

inquiry

Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm

2-Amino-4-chlorophenol-6-sulfonic acid CAS NO.88-23-3

Cas:88-23-3

Min.Order:1 Metric Ton

FOB Price: $1.0 / 3.0

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 3-amino-5-chloro-2-hydroxybenzenesulphonic acid

Cas:88-23-3

Min.Order:1

Negotiable

Type:Other

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% 2-Amino-4-chlorophenol-6-sulfonic acid 88-23-3 ISO Producer

Cas:88-23-3

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

6-Amino-4-chlorophenol-2-sulfonic acid

Cas:88-23-3

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

2-Amino-4-chlorophenol-6-sulfonic acid

Cas:88-23-3

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 88-23-3 with competitive price

Cas:88-23-3

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Product Name: 2-Amino-4-chlorophenol-6-sulfonic acid Synonyms: Metanilic acid, 5-chloro-2-hydroxy-;Metanilic acid, 5-chloro-2-hydroxy- (8CI);3-amino-5-chloro-2-hydroxy-benzenesulfonicaci;2-AMINO-4-CHLOROPHE

2-Amino-4-chlorophenol-6-sulfonic acid

Cas:88-23-3

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2-Amino-4-chlorophenol-6-sulfonic acid 88-23-3

Cas:88-23-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

2-Amino-4-chlorophenol-6-sulfonic acid CAS:88-23-3 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quali

2-Amino-4-chlorophenol-6-sulfonic acid CAS:88-23-3

Cas:88-23-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2-Amino-4-chlorophenol-6-sulfonic acid

Cas:88-23-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

2-Amino-4-chlorophenol-6-sulfonic acid

Cas:88-23-3

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

2-Amino-4-chlorophenol-6-sulfonic acid

Cas:88-23-3

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

4-Chloro-2-aminophenol-6-sulfonic acid

Cas:88-23-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High purity 3-amino-5-chloro-2-hydroxybenzenesulfonic acid

Cas:88-23-3

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

2-Amino-4-chlorophenol-6-sulfonic acid 88-23-3

Cas:88-23-3

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

superior quality Appearance:Off-white solid. Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application:Used as dye intermediates for synthesis of acidic med

4 chloro 2 aminophenol 6 sulfonic acid

Cas:88-23-3

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so

2-Amino-4-chlorophenol-6-sulfonic acid 88-23-3

Cas:88-23-3

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

2-Amino-4-chlorophenol-6-sulfonic acid

Cas:88-23-3

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

High Purity 2-Amino-4-chlorophenol-6-sulfonic acid

Cas:88-23-3

Min.Order:0

Negotiable

Type:Trading Company

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

2-Amino-4-chlorophenol-6-sulfonic acid

Cas:88-23-3

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

2-Amino-4-chlorophenol-6-sulfonic acid

Cas:88-23-3

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

2-Amino-4-chlorophenol-6-sulfonic acid

Cas:88-23-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

2-Amino-4-chlorophenol-6-sulfonic acid 88-23-3

Cas:88-23-3

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

4-Chloro-2-aminophenol-6-sulfonic acid

Cas:88-23-3

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

2-Amino-4-chlorophenol-6-sulfonic acid

Cas:88-23-3

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

2-Amino-4-chlorophenol-6-sulfonic acid 88-23-3

Cas:88-23-3

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

2-Amino-4-chlorophenol-6-sulfonic acid 88-23-3

Cas:88-23-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

3-amino-5-chloro-2-hydroxybenzenesulfonic acid

Cas:88-23-3

Min.Order:0

Negotiable

Type:Other

inquiry

Synthetic route

5-chloro-2-hydroxy-3-nitro-benzenesulfonic acid
88-25-5

5-chloro-2-hydroxy-3-nitro-benzenesulfonic acid

2-amino-4-chlorophenol-6-sulfonic acid
88-23-3

2-amino-4-chlorophenol-6-sulfonic acid

2-hydroxy-5-chloro-aniline
95-85-2

2-hydroxy-5-chloro-aniline

2-amino-4-chlorophenol-6-sulfonic acid
88-23-3

2-amino-4-chlorophenol-6-sulfonic acid

Conditions
ConditionsYield
With sulfuric acid
With sulfuric acid
N-(5-chloro-2-hydroxyphenyl)acetamide
26488-93-7

N-(5-chloro-2-hydroxyphenyl)acetamide

2-amino-4-chlorophenol-6-sulfonic acid
88-23-3

2-amino-4-chlorophenol-6-sulfonic acid

Conditions
ConditionsYield
durch Sulfurieren und Verseifen des Reaktionsproduktes;
durch Sulfurien und Verseifen des Reaktionsproduktes;
2-amino-4-chlorophenol-6-sulfonic acid
88-23-3

2-amino-4-chlorophenol-6-sulfonic acid

acetylacetone
123-54-6

acetylacetone

3-(5-chloro-2-hydroxy-3-sulfophenylhydrazo)pentane-2,4-dione
1246887-50-2

3-(5-chloro-2-hydroxy-3-sulfophenylhydrazo)pentane-2,4-dione

Conditions
ConditionsYield
Stage #1: 2-amino-4-chlorophenol-6-sulfonic acid With hydrogenchloride; sodium hydroxide; sodium nitrite In water at 0 - 5℃;
Stage #2: acetylacetone With sodium hydroxide In water Cooling with ice;
77%
2-amino-4-chlorophenol-6-sulfonic acid
88-23-3

2-amino-4-chlorophenol-6-sulfonic acid

1-phenylbutan-1,3-dione
93-91-4

1-phenylbutan-1,3-dione

1-phenyl-2-(2-hydroxy-3-sulfo-5-chlorophenylhydrazo)butane-1,3-dione

1-phenyl-2-(2-hydroxy-3-sulfo-5-chlorophenylhydrazo)butane-1,3-dione

Conditions
ConditionsYield
Stage #1: 2-amino-4-chlorophenol-6-sulfonic acid With hydrogenchloride; sodium hydroxide; sodium nitrite In water at 0 - 5℃; Japp-Klingemann reaction;
Stage #2: 1-phenylbutan-1,3-dione With sodium acetate In ethanol; water Japp-Klingemann reaction; Cooling with ice;
77%
2-amino-4-chlorophenol-6-sulfonic acid
88-23-3

2-amino-4-chlorophenol-6-sulfonic acid

dimedone
126-81-8

dimedone

5-chloro-3-(2-(4,4-dimethyl-2,6-dioxocyclohexylidene)hydrazinyl)-2-hydroxy-benzenesulfonic acid
1393845-94-7

5-chloro-3-(2-(4,4-dimethyl-2,6-dioxocyclohexylidene)hydrazinyl)-2-hydroxy-benzenesulfonic acid

Conditions
ConditionsYield
Stage #1: 2-amino-4-chlorophenol-6-sulfonic acid With sodium hydroxide; sodium nitrite In water at -0.16℃;
Stage #2: With hydrogenchloride In water at 4.84℃; for 1h;
Stage #3: dimedone With sodium hydroxide In ethanol; water at -0.16℃; Japp-Klingemann Hydrazone Synthesis;
75%
2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one
277299-70-4

2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one

2-amino-4-chlorophenol-6-sulfonic acid
88-23-3

2-amino-4-chlorophenol-6-sulfonic acid

5-chloro-3-{[1-(3,4-dimethylphenyl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl]azo}-2-hydroxybenzenesulfonic acid

5-chloro-3-{[1-(3,4-dimethylphenyl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl]azo}-2-hydroxybenzenesulfonic acid

Conditions
ConditionsYield
34%
phosgene
75-44-5

phosgene

2-amino-4-chlorophenol-6-sulfonic acid
88-23-3

2-amino-4-chlorophenol-6-sulfonic acid

5-chloro-2-oxo-2,3-dihydro-benzoxazole-7-sulfonic acid

5-chloro-2-oxo-2,3-dihydro-benzoxazole-7-sulfonic acid

Conditions
ConditionsYield
With sodium hydroxide at 5 - 10℃;
2-methyl-5-nitrobenzene-1-sulfonyl chloride
121-02-8

2-methyl-5-nitrobenzene-1-sulfonyl chloride

2-amino-4-chlorophenol-6-sulfonic acid
88-23-3

2-amino-4-chlorophenol-6-sulfonic acid

3-(4-amino-toluene-2-sulfonylamino)-5-chloro-2-hydroxy-benzenesulfonic acid
6528-45-6

3-(4-amino-toluene-2-sulfonylamino)-5-chloro-2-hydroxy-benzenesulfonic acid

Conditions
ConditionsYield
nachfolgend Reduktion;
2-amino-4-chlorophenol-6-sulfonic acid
88-23-3

2-amino-4-chlorophenol-6-sulfonic acid

3-amino-5-chloro-2-hydroxy-benzenesulfonyl chloride

3-amino-5-chloro-2-hydroxy-benzenesulfonyl chloride

2-amino-4-chlorophenol-6-sulfonic acid
88-23-3

2-amino-4-chlorophenol-6-sulfonic acid

5-chloro-3-hydrazino-2-hydroxy-benzenesulfonic acid

5-chloro-3-hydrazino-2-hydroxy-benzenesulfonic acid

Conditions
ConditionsYield
Diazotization.Erhitzen der Diazoverbindung mit NaHSO3-Loesung und Soda und Kochen des Reaktionsprodukts mit verd. Schwefelsaeure;
bromocyane
506-68-3

bromocyane

2-amino-4-chlorophenol-6-sulfonic acid
88-23-3

2-amino-4-chlorophenol-6-sulfonic acid

2-amino-5-chloro-benzooxazole-7-sulfonic acid
64037-29-2

2-amino-5-chloro-benzooxazole-7-sulfonic acid

Conditions
ConditionsYield
(i) MeOH, (ii) H2O; Multistep reaction;
phosgene
75-44-5

phosgene

2-amino-4-chlorophenol-6-sulfonic acid
88-23-3

2-amino-4-chlorophenol-6-sulfonic acid

furan-2,3,5(4H)-trione pyridine (1:1)

furan-2,3,5(4H)-trione pyridine (1:1)

5-chloro-benzoxazolone-sulfonic acid-(7)

5-chloro-benzoxazolone-sulfonic acid-(7)

Conditions
ConditionsYield
at 5 - 10℃;
2-amino-4-chlorophenol-6-sulfonic acid
88-23-3

2-amino-4-chlorophenol-6-sulfonic acid

5-chloro-2-hydroxy-3-(3-methyl-5-oxo-2,5-dihydro-pyrazol-1-yl)-benzenesulfonic acid

5-chloro-2-hydroxy-3-(3-methyl-5-oxo-2,5-dihydro-pyrazol-1-yl)-benzenesulfonic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Diazotization.Erhitzen der Diazoverbindung mit NaHSO3-Loesung und Soda und Kochen des Reaktionsprodukts mit verd. Schwefelsaeure
View Scheme
2-amino-4-chlorophenol-6-sulfonic acid
88-23-3

2-amino-4-chlorophenol-6-sulfonic acid

1-(5-chloro-2-hydroxy-3-sulfo-phenyl)-5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylic acid

1-(5-chloro-2-hydroxy-3-sulfo-phenyl)-5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Diazotization.Erhitzen der Diazoverbindung mit NaHSO3-Loesung und Soda und Kochen des Reaktionsprodukts mit verd. Schwefelsaeure
2: natrium carbonate
View Scheme
2-amino-4-chlorophenol-6-sulfonic acid
88-23-3

2-amino-4-chlorophenol-6-sulfonic acid

N-tert-butoxycarbonyl glutamic acid tert-butyl ester
24277-39-2

N-tert-butoxycarbonyl glutamic acid tert-butyl ester

(2S)-2-amino-4-[(5-chloro-2-hydroxy-3-sulfophenyl)carbamoyl]butanoic acid
1220125-05-2

(2S)-2-amino-4-[(5-chloro-2-hydroxy-3-sulfophenyl)carbamoyl]butanoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: diisopropyl-carbodiimide; triethylamine; benzotriazol-1-ol / N,N-dimethyl-formamide / 0 - 20 °C
2: trifluoroacetic acid / 20 °C
View Scheme
Stage #1: 2-amino-4-chlorophenol-6-sulfonic acid; N-tert-butoxycarbonyl glutamic acid tert-butyl ester With pyridine; 1-hydroxy-7-aza-benzotriazole; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃;
Stage #2: With trifluoroacetic acid at 20℃; for 1.5h;
Multi-step reaction with 2 steps
1: triethylamine; benzotriazol-1-ol; diisopropyl-carbodiimide / N,N-dimethyl-formamide / 0 - 20 °C
2: trifluoroacetic acid / N,N-dimethyl-formamide / 2 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: benzotriazol-1-ol; diisopropyl-carbodiimide; triethylamine / N,N-dimethyl-formamide / 0 - 20 °C
2: trifluoroacetic acid / 2 h / 20 °C
View Scheme
2-amino-4-chlorophenol-6-sulfonic acid
88-23-3

2-amino-4-chlorophenol-6-sulfonic acid

N-tert-butoxycarbonyl glutamic acid tert-butyl ester
24277-39-2

N-tert-butoxycarbonyl glutamic acid tert-butyl ester

C20H29ClN2O9S
1333219-82-1

C20H29ClN2O9S

Conditions
ConditionsYield
With benzotriazol-1-ol; triethylamine; diisopropyl-carbodiimide In N,N-dimethyl-formamide at 0 - 20℃;
With benzotriazol-1-ol; triethylamine; diisopropyl-carbodiimide In N,N-dimethyl-formamide at 0 - 20℃;
Cbz-(L)-Glu-OBn
3705-42-8

Cbz-(L)-Glu-OBn

2-amino-4-chlorophenol-6-sulfonic acid
88-23-3

2-amino-4-chlorophenol-6-sulfonic acid

N5-(2-hydroxy-3-sulfophenyl)-L-glutamine
1220125-08-5

N5-(2-hydroxy-3-sulfophenyl)-L-glutamine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: 1,1'-carbonyldiimidazole / dichloromethane / 0.5 h / 20 °C
1.2: 20 °C
2.1: hydrogen / palladium on carbon / water; methanol / 20 °C
View Scheme
Cbz-(L)-Glu-OBn
3705-42-8

Cbz-(L)-Glu-OBn

2-amino-4-chlorophenol-6-sulfonic acid
88-23-3

2-amino-4-chlorophenol-6-sulfonic acid

C26H25ClN2O9S

C26H25ClN2O9S

Conditions
ConditionsYield
Stage #1: Cbz-(L)-Glu-OBn With 1,1'-carbonyldiimidazole In dichloromethane at 20℃; for 0.5h;
Stage #2: 2-amino-4-chlorophenol-6-sulfonic acid In tetrahydrofuran; dichloromethane at 20℃;
2-amino-4-chlorophenol-6-sulfonic acid
88-23-3

2-amino-4-chlorophenol-6-sulfonic acid

ethyl acetoacetate
141-97-9

ethyl acetoacetate

C12H13ClN2O7S

C12H13ClN2O7S

Conditions
ConditionsYield
Stage #1: 2-amino-4-chlorophenol-6-sulfonic acid With hydrogenchloride; sodium hydroxide; sodium nitrite In water at 4.84℃; for 1h; Cooling with ice;
Stage #2: ethyl acetoacetate With sodium acetate In ethanol at -0.16℃; for 1h; Cooling with ice;
Boc-Glu(OBzl)-OH
13574-13-5

Boc-Glu(OBzl)-OH

2-amino-4-chlorophenol-6-sulfonic acid
88-23-3

2-amino-4-chlorophenol-6-sulfonic acid

benzylamine
100-46-9

benzylamine

3-[(4S)-4-amino-4-(benzylcarbamoyl)butanamide]-5-chloro-2-hydroxybenzene-1-sulfonic acid
1333218-58-8

3-[(4S)-4-amino-4-(benzylcarbamoyl)butanamide]-5-chloro-2-hydroxybenzene-1-sulfonic acid

Conditions
ConditionsYield
Stage #1: Boc-Glu(OBzl)-OH; benzylamine With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane
Stage #2: With lithium hydroxide In tetrahydrofuran; methanol; water at 20℃; for 2h;
Stage #3: 2-amino-4-chlorophenol-6-sulfonic acid
(2S)-2-[(tert-butoxy)carbonylamino]-4-(methoxycarbonyl)butanoic acid
45214-91-3

(2S)-2-[(tert-butoxy)carbonylamino]-4-(methoxycarbonyl)butanoic acid

2-amino-4-chlorophenol-6-sulfonic acid
88-23-3

2-amino-4-chlorophenol-6-sulfonic acid

phenethylamine
64-04-0

phenethylamine

3-[(4S)-4-amino-4-[(2-phenylethyl)carbamoyl]butanamide]-5-chloro-2-hydroxybenzene-1-sulfonic acid
1333218-59-9

3-[(4S)-4-amino-4-[(2-phenylethyl)carbamoyl]butanamide]-5-chloro-2-hydroxybenzene-1-sulfonic acid

Conditions
ConditionsYield
Stage #1: (2S)-2-[(tert-butoxy)carbonylamino]-4-(methoxycarbonyl)butanoic acid; phenethylamine With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane
Stage #2: With lithium hydroxide In tetrahydrofuran; methanol; water
Stage #3: 2-amino-4-chlorophenol-6-sulfonic acid
151.9 mg
methanesulfonamide
3144-09-0

methanesulfonamide

Boc-Glu(OBzl)-OH
13574-13-5

Boc-Glu(OBzl)-OH

2-amino-4-chlorophenol-6-sulfonic acid
88-23-3

2-amino-4-chlorophenol-6-sulfonic acid

3-[(45)-4-amino-4-(methanesulfonylcarbamoyl)butanamide]-5-chloro-2-hydroxybenzene-1-sulfonic acid
1333218-70-4

3-[(45)-4-amino-4-(methanesulfonylcarbamoyl)butanamide]-5-chloro-2-hydroxybenzene-1-sulfonic acid

Conditions
ConditionsYield
Stage #1: methanesulfonamide; Boc-Glu(OBzl)-OH With dmap; triethylamine In dichloromethane at 20℃;
Stage #2: With palladium 10% on activated carbon; hydrogen In ethyl acetate
Stage #3: 2-amino-4-chlorophenol-6-sulfonic acid With 1-hydroxy-7-aza-benzotriazole; triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide
15.3 mg
2-amino-4-chlorophenol-6-sulfonic acid
88-23-3

2-amino-4-chlorophenol-6-sulfonic acid

N-tert-butoxycarbonyl glutamic acid tert-butyl ester
24277-39-2

N-tert-butoxycarbonyl glutamic acid tert-butyl ester

(2S)-4-[(5-chloro-2-hydroxy-3-sulfophenyl)carbamoyl]-2-(dimethylamino)butanoic acid
1333219-13-8

(2S)-4-[(5-chloro-2-hydroxy-3-sulfophenyl)carbamoyl]-2-(dimethylamino)butanoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: 1-hydroxy-7-aza-benzotriazole; pyridine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate / N,N-dimethyl-formamide / 20 °C
1.2: 1.5 h / 20 °C
2.1: hydrogen; palladium 10% on activated carbon / water
View Scheme
(4S)-4-(N-tert-butoxycarbonylamino)-4-(5-ethyl-1,3,4-oxadiazole-2-yl)butanoic acid
1333219-62-7

(4S)-4-(N-tert-butoxycarbonylamino)-4-(5-ethyl-1,3,4-oxadiazole-2-yl)butanoic acid

2-amino-4-chlorophenol-6-sulfonic acid
88-23-3

2-amino-4-chlorophenol-6-sulfonic acid

3-[(4S)-4-(N-tert-butoxycarbonylamino)-4-(5-ethyl-1,3,4-oxadiazole-2-yl)butanamide]-5-chloro-2-hydroxybenzene-1-sulfonic acid
1333219-63-8

3-[(4S)-4-(N-tert-butoxycarbonylamino)-4-(5-ethyl-1,3,4-oxadiazole-2-yl)butanamide]-5-chloro-2-hydroxybenzene-1-sulfonic acid

Conditions
ConditionsYield
With 1-hydroxy-7-aza-benzotriazole; triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In dichloromethane at 20℃;9 mg
(4S)-4-(N-tert-butoxycarbonylamino)-4-(ethylcarbamoyl)butanoic acid
70962-77-5

(4S)-4-(N-tert-butoxycarbonylamino)-4-(ethylcarbamoyl)butanoic acid

2-amino-4-chlorophenol-6-sulfonic acid
88-23-3

2-amino-4-chlorophenol-6-sulfonic acid

3-[(4S)-4-(N-tert-butoxycarbonylamino)-4-(ethylcarbamoyl)butanamide]-5-chloro-2-hydroxybenzene-1-sulfonic acid
1333219-64-9

3-[(4S)-4-(N-tert-butoxycarbonylamino)-4-(ethylcarbamoyl)butanamide]-5-chloro-2-hydroxybenzene-1-sulfonic acid

Conditions
ConditionsYield
With 1-hydroxy-7-aza-benzotriazole; triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In dichloromethane
tert-butyl (2S)-3-amino-2-{[(tert-butoxy)carbonyl]amino}propanoate hydrochloride
1333246-31-3

tert-butyl (2S)-3-amino-2-{[(tert-butoxy)carbonyl]amino}propanoate hydrochloride

2-amino-4-chlorophenol-6-sulfonic acid
88-23-3

2-amino-4-chlorophenol-6-sulfonic acid

(2S)-2-amino-3-{[(5-chloro-2-hydroxy-3-sulfophenyl)carbamoyl]amino}propanoic acid
1333218-42-0

(2S)-2-amino-3-{[(5-chloro-2-hydroxy-3-sulfophenyl)carbamoyl]amino}propanoic acid

Conditions
ConditionsYield
Stage #1: tert-butyl (2S)-3-amino-2-{[(tert-butoxy)carbonyl]amino}propanoate hydrochloride; 2-amino-4-chlorophenol-6-sulfonic acid With pyridine; bis(trichloromethyl) carbonate In dichloromethane at 20℃;
Stage #2: With trifluoroacetic acid In dichloromethane for 5h;
20.1 mg
2-amino-4-chlorophenol-6-sulfonic acid
88-23-3

2-amino-4-chlorophenol-6-sulfonic acid

(2S)-2-amino-3-{[(2-hydroxy-3-sulfophenyl)carbamoyl] amino} propanoic acid
1333218-64-6

(2S)-2-amino-3-{[(2-hydroxy-3-sulfophenyl)carbamoyl] amino} propanoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: bis(trichloromethyl) carbonate; pyridine / dichloromethane / 20 °C
1.2: 5 h
2.1: hydrogen; palladium on activated charcoal / water; methanol / 72 h
View Scheme
2-amino-4-chlorophenol-6-sulfonic acid
88-23-3

2-amino-4-chlorophenol-6-sulfonic acid

3-[(4S)-4-(N-tert-butoxycarbonylamino)-4-(5-ethyl-1,3,4-oxadiazole-2-yl)butanamide]-5-chloro-2-hydroxybenzene-1-sulfonic acid
1333219-63-8

3-[(4S)-4-(N-tert-butoxycarbonylamino)-4-(5-ethyl-1,3,4-oxadiazole-2-yl)butanamide]-5-chloro-2-hydroxybenzene-1-sulfonic acid

Conditions
ConditionsYield
With 1-hydroxy-7-aza-benzotriazole; triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In dichloromethane at 20℃;

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