1018-79-7

Basic information

• Product Name: 1,4-DIHYDROXY-2,3-NAPHTHALENEDICARBONITRILE
• Synonyms: 1,4-dihydroxynaphthalene-2,3-dicarbo-nitrile;1 4-DIHYDROXY-2 3-NAPHTHALENEDICARBO- &;1,4-Dihydroxy-2,3-naphthalenedicarbonitrile
• CAS NO: 1018-79-7
• Molecular Formula: C₁₂H₆N₂O₂
• Molecular Weight: 210.18824
• Mol File: 1018-79-7.mol
• Article Data: 7

Chemical Properties

• Melting Point: >300 °C(lit.)
• Boiling Point: 534 °C at 760 mmHg
• Flash Point: 276.8 °C
• Appearance: /
• Density: 1.51 g/cm³
• Vapor Pressure: 5.1E-12mmHg at 25°C
• Refractive Index: 1.752
• PKA: 5.91±0.50(Predicted)
• BRN: 2695423
• CAS DataBase Reference: 1,4-DIHYDROXY-2,3-NAPHTHALENEDICARBONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-DIHYDROXY-2,3-NAPHTHALENEDICARBONITRILE(1018-79-7)
• EPA Substance Registry System: 1,4-DIHYDROXY-2,3-NAPHTHALENEDICARBONITRILE(1018-79-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• WGK Germany: 3
• Hazardous Substances Data: 1018-79-7(Hazardous Substances Data)

Usage

Description

1,4-Dihydroxy-2,3-naphthalenedicarbonitrile is a chemical compound belonging to the naphthalene family, characterized by the presence of two hydroxyl groups and two nitrile groups in its molecular structure. It is known for its unique properties and potential applications in various industries.

Uses

Used in Dye Industry:
1,4-Dihydroxy-2,3-naphthalenedicarbonitrile is used as an intermediate in the synthesis of various dyes due to its chemical structure and reactivity. Its ability to form different color compounds makes it a valuable component in the production of dyes for various applications.
Used in Pharmaceutical Industry:
1,4-Dihydroxy-2,3-naphthalenedicarbonitrile is used as a key building block in the development of new pharmaceutical compounds. Its unique molecular structure allows for the creation of novel drugs with potential therapeutic applications.
Used in Metabolite Research:
1,4-Dihydroxy-2,3-naphthalenedicarbonitrile is utilized in the study of metabolites, which are the byproducts of various biochemical processes in living organisms. Its chemical properties make it a useful tool for understanding the metabolic pathways and identifying potential biomarkers for various diseases.

InChI:InChI=1/C12H6N2O2/c13-5-9-10(6-14)12(16)8-4-2-1-3-7(8)11(9)15/h1-4,15-16H

Upstream product

• 117-80-6 2,3-Dichloro-1,4-naphthoquinone 
• 143-33-9 sodium cyanide 
• 1455-77-2 guanazole 
• 1018-78-6 2,3-dicyano-1,4-naphthoquinone 
• 3929-18-8 N³-(p-tolyl)-1H-1,2,4-triazole-3,5-diamine 
• 3673-06-1 N,N'-dicyclohexylethylenediimine 
• 24764-92-9 1,4-bis(p-tolyl)-1,4-diaza-1,3-butadiene 
• 24978-42-5 1,4-bis(4'-methoxyphenyl)-1,4-diazabuta-1,3-diene 
• 16954-74-8 (1,3-dioxoindan-2-ylidene)propanedinitrile 
• 764-42-1 butenedinitrile 
• 113674-51-4 2-Carbobenzoxybenzaldehyde 

Downstream Products

• 116453-89-5 1,4-dibutoxy-2,3-naphthalocyaninedicarbonitrile 
• 1018-78-6 2,3-dicyano-1,4-naphthoquinone 
• 105528-25-4 5,9,14,18,23,27,32,36-octa-n-butoxy-2,3-naphthalocyanine 

Relevant articles and documents

N-Heterocyclic carbene based catalytic platform for Hauser-Kraus annulations

The venerable Hauser-Kraus annulation is an effective and convergent method for generating oxygenated polycyclic aromatic compounds. Despite its application in complex molecule synthesis, the harsh and strongly basic conditions can limit its utility in more functionalized molecular settings. We have developed the first catalytic Hauser-Kraus annulation based on N-heterocyclic carbene catalysis that proceeds under milder conditions. We demonstrate the scope of the transformation in the presence of several functional groups. We also propose a concerted mechanism for the annulation that proceeds through a non-canonical Breslow intermediate. This journal is

Studies on charge-transfer complexes of 2,3-dicyano-1,4-naphthoquinone with some ring and N-substituted anilines

The charge-transfer complexes (CT-complexes) between 2,3-dicyano-1,4- naphthoquinone (DCNQ) and some aromatic anilines, both ring and N-substituted, were studied spectrophotometrically in three chlorinated solvents, viz. chloroform, dichloromethane, and 1,2-dichloroethane at different temperatures. All the donors are known to form stable 1:1 stoichiometric complexes with DCNQ and their stoichiometry was unaffected by the variation of temperature over the studied range. The change in polarity of the solvent also doesn't affect the stoichiometry of the complexes. The determined formation constant values are in the range of 0.49-10.8 dm3 mol-1, the highest is for the N-benzylaniline and the lowest is for o-chloroaniline. The effect of functional groups on the aniline moiety towards the strength and its electron releasing property has been discussed. The ΔH, ΔS, and ΔG values are all negative, so the studied complexes are reasonably stable and exothermic in nature. The ionization potentials of the donors were determined using the charge-transfer (CT) absorption bands of the complexes. The dissociation energies (W) of the charge-transfer excited state for the CT-complexes were also determined and are found to be constant. Springer-Verlag 2004.

A novel synthesis of 1,2,4-triazolo[1,5-a]isoindolinetrione, 1,2,4-triazolo[1,5-a]pyrimidine and 1,2,4-triazolo[2,3-a]quinazolinedione derivatives and their antibacterial activity.

-