117836-13-2

Basic information

• Product Name: (S)-1-Cbz-5-oxo-piperidine-2-carboxylic acid Methyl ester
• Synonyms: (S)-1-Cbz-5-oxo-piperidine-2-carboxylic acid Methyl ester;1-benzyl 2-methyl (2S)-5-oxopiperidine-1,2-dicarboxylate;(S)-1-Benzyl 2-methyl 5-oxopiperidine-1,2-dicarboxylate
• CAS NO: 117836-13-2
• Molecular Formula: C₁₅H₁₇NO₅
• Molecular Weight: 291.29918
• Mol File: 117836-13-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (S)-1-Cbz-5-oxo-piperidine-2-carboxylic acid Methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-Cbz-5-oxo-piperidine-2-carboxylic acid Methyl ester(117836-13-2)
• EPA Substance Registry System: (S)-1-Cbz-5-oxo-piperidine-2-carboxylic acid Methyl ester(117836-13-2)

Safety Data

• Hazardous Substances Data: 117836-13-2(Hazardous Substances Data)

Usage

General Description

The chemical compound (S)-1-Cbz-5-oxo-piperidine-2-carboxylic acid Methyl ester is a methyl ester derivative of 5-oxo-piperidine-2-carboxylic acid. It is a white to off-white crystalline powder that is used in the synthesis of pharmaceuticals and other organic compounds. The presence of the carboxylic acid and methyl ester groups make it suitable for use as a building block in the production of various drugs and bioactive molecules. (S)-1-Cbz-5-oxo-piperidine-2-carboxylic acid Methyl ester has potential applications in medicinal chemistry, drug discovery, and chemical research, making it an important intermediate in the synthesis of biologically active compounds.

Upstream product

• 15366-19-5 methyl (S)-2-benzyloxycarbonylamino-6-diazo-5-oxohexanoate 
• 13907-82-9 N²-benzyloxycarbonyl-L-glutamine methyl ester 
• 5672-83-3 Z-L-GluOMe 
• 117836-15-4 (S)-2-Benzyloxycarbonylamino-5-ethoxycarbonyloxy-5-oxo-pentanoic acid methyl ester 
• 23632-67-9 (S)-3-[3-(benzyloxycarbonyl)-5-oxooxazolidin-4-yl]propanoic acid 
• 154061-64-0 (2S)-2-<(Benzyloxycarbonyl)amino>-6-hydroxyhexanoic acid methyl ester 
• 227758-97-6 (2S)-3,4-dihydro-2H-pyridine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester 
• 824943-45-5 (2S,5R)-5-hydroxy-6-methoxy-piperidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester 
• 110-87-2 3,4-dihydro-2H-pyran 
• 44601-24-3 4-hydroxypentanal 
• 121895-18-9 (S)-2-amino-6-hydroxyhexanoic acid methyl ester hydrochloride 

Downstream Products

• 117836-26-7 cis-5(S)-hydroxy-2(S)-N₁-benzyloxycarbonylpipecolic acid methyl ester 
• 917507-80-3 (2S,5S)-N-[(benzyloxy)carbonyl]-5-hydroxy-2-piperidinecarboxylic acid 
• 63088-78-8 (2S,5R)-5-hydroxypiperidine-2-carboxylic acid 

Relevant articles and documents

MANUFACTURING METHOD OF (2S,5S)-5-HYDROXY-2-PIPERIDINECARBOXYLIC ACID AS WELL AS MANUFACTURING INTERMEDIATE OF THE SAME AND METHOD FOR MANUFACTURING THE SAME

PROBLEM TO BE SOLVED: To provide synthesis methods of 5-hydroxy-6-methoxypiperidine-2-carboxylic acid derivatives and 5-oxopiperidine-2-carboxylic acid derivatives more safely than ever by using inexpensive raw ingredients. SOLUTION: In the provided method, a compound expressed by the following formula [X] is manufactured from a compound expressed by the following formula [I] through steps (1) through (9) [either steps (4) and (5) or steps (6) and (7) in the case of steps (4) through (7)]. COPYRIGHT: (C)2015,JPOandINPIT

Synthesis of 5-oxo-L-pipecolic acid derivatives by rhodium(II) acetate catalyzed cyclization of diazoketones

A convenient synthesis of 5-oxo-L-pipecolic acid derivatives is described. The key step involves the rhodium(II) acetate catalysed N-H insertion reaction of diazoketones, which are derived from L-glutamic acid.