1214270-80-0Relevant articles and documents
Process development of a diacyl glycerolacyltransferase-1 inhibitor
Ravn, Matthew M.,Wagaw, Seble H.,Engstrom, Kenneth M.,Mei, Jianzhang,Kotecki, Brian,Souers, Andrew J.,Kym, Philip R.,Judd, Andrew S.,Zhao, Gang
, p. 417 - 424 (2011/04/22)
A synthesis of a selective diacyl glycerolacyltransferase-1 (DGAT-1) inhibitor, 1, is described. The synthesis illustrates a diketone Favorskii reaction on 9 in place of the more common ketoester variant for generation of the dicarboxycyclopentane core, t