791594-13-3

Basic information

• Product Name: CYCLOPENTANECARBOXYLIC ACID, 2-(4-BROMOBENZOYL)-, (1R,2R)-
• Synonyms: CYCLOPENTANECARBOXYLIC ACID, 2-(4-BROMOBENZOYL)-, (1R,2R)-;(1R,2R)-2-(4-bromobenzoyl)cyclopentane-1-carboxylic acid
• CAS NO: 791594-13-3
• Molecular Formula: C₁₃H₁₃BrO₃
• Molecular Weight: 297.147
• Mol File: 791594-13-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 455.4°C at 760 mmHg
• Flash Point: 229.2°C
• Appearance: /
• Density: 1.53g/cm³
• Vapor Pressure: 4.38E-09mmHg at 25°C
• Refractive Index: 1.6
• CAS DataBase Reference: CYCLOPENTANECARBOXYLIC ACID, 2-(4-BROMOBENZOYL)-, (1R,2R)-(CAS DataBase Reference)
• NIST Chemistry Reference: CYCLOPENTANECARBOXYLIC ACID, 2-(4-BROMOBENZOYL)-, (1R,2R)-(791594-13-3)
• EPA Substance Registry System: CYCLOPENTANECARBOXYLIC ACID, 2-(4-BROMOBENZOYL)-, (1R,2R)-(791594-13-3)

Safety Data

• Hazardous Substances Data: 791594-13-3(Hazardous Substances Data)

Usage

General Description

Cyclopentanecarboxylic acid, 2-(4-bromobenzoyl)-, (1R,2R)- is a specific chemical compound with potential applications in the pharmaceutical industry. It is a chiral molecule, meaning it has a non-superimposable mirror image, and is often used in the synthesis of other compounds. The presence of the bromine atom and the specific arrangement of atoms in the molecule give it unique properties that make it useful as a building block in the production of pharmaceuticals and other organic compounds. However, it is important to handle and use this chemical with care due to its potential hazards and toxicity.

InChI:InChI=1/C13H13BrO3/c14-9-6-4-8(5-7-9)12(15)10-2-1-3-11(10)13(16)17/h4-7,10-11H,1-3H2,(H,16,17)/t10-,11-/m1/s1

Upstream product

• 1019115-10-6 trans-(+/-)-2-(4-bromobenzoyl)cyclopentanecarboxylic acid 
• 1019115-10-6 trans-2-(4-bromobenzoyl)cyclopentanecarboxylic acid 
• 791594-11-1 methyl cis-2-(4-bromobenzoyl)cyclopentanecarboxylate 
• 1214270-80-0 2-bromo-6-(4-bromobenzoyl)cyclohexanone 
• 108-94-1 cyclohexanone 
• 1655-07-8 ethyl 2-oxocyclohexane carboxylate 
• 586-75-4 4-chlorobenzoyl chloride 

Downstream Products

• 791594-14-4 methyl (1R,2R)-2-(4-bromobenzoyl)cyclopentanecarboxylate 
• 959122-11-3 (1R,2R)-2-[[4'-[(phenylamino)carbonyl]amino][1,1'-biphenyl-4-yl]carbonyl]cyclopentanecarboxylic acid 
• 959122-10-2 (1R,2R)-2-({4'-[(anilinocarbonyl)amino]-1,1'-biphenyl-4-yl}carbonyl)cyclopentanecarboxylic acid methyl ester 

Relevant articles and documents

Process development of a diacyl glycerolacyltransferase-1 inhibitor

A synthesis of a selective diacyl glycerolacyltransferase-1 (DGAT-1) inhibitor, 1, is described. The synthesis illustrates a diketone Favorskii reaction on 9 in place of the more common ketoester variant for generation of the dicarboxycyclopentane core, t

Validation of diacyl glycerolacyltransferase I as a novel target for the treatment of obesity and dyslipidemia using a potent and selective small molecule inhibitor

A highly potent and selective DGAT-1 inhibitor was identified and used in rodent models of obesity and postprandial chylomicron excursion to validate DGAT-1 inhibition as a novel approach for the treatment of metabolic diseases. Specifically, compound 4a conferred weight loss and a reduction in liver triglycerides when dosed chronically in DIO mice and depleted serum triglycerides following a lipid challenge in a dose-dependent manner, thus, reproducing major phenotypical characteristics of DGAT-1-/- mice.