791594-11-1

Basic information

• Product Name: (+/-)-CIS-2-(4-BROMO-BENZOYL)-CYCLOPENTANECARBOXYLIC ACID METHYL ESTER
• Synonyms: (1S,2R)-Methyl 2-(4-broMobenzoyl)cyclopentanecarboxylate,CIS;(+/-)-CIS-2-(4-BROMO-BENZOYL)-CYCLOPENTANECARBOXYLIC ACID METHYL ESTER;Methyl cis-2-(4-bromobenzoyl)cyclopentanecarboxylate
• CAS NO: 791594-11-1
• Molecular Formula: C14H15BrO3
• Molecular Weight: 311.1711
• Mol File: 791594-11-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 394.8±37.0 °C(Predicted)
• Appearance: /
• Density: 1.417
• CAS DataBase Reference: (+/-)-CIS-2-(4-BROMO-BENZOYL)-CYCLOPENTANECARBOXYLIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-CIS-2-(4-BROMO-BENZOYL)-CYCLOPENTANECARBOXYLIC ACID METHYL ESTER(791594-11-1)
• EPA Substance Registry System: (+/-)-CIS-2-(4-BROMO-BENZOYL)-CYCLOPENTANECARBOXYLIC ACID METHYL ESTER(791594-11-1)

Safety Data

• Hazardous Substances Data: 791594-11-1(Hazardous Substances Data)

Usage

Description

(+/-)-CIS-2-(4-BROMO-BENZOYL)-CYCLOPENTANECARBOXYLIC ACID METHYL ESTER is a cyclopentanecarboxylic acid methyl ester with the molecular formula C13H15BrO3 and a molecular weight of 299.16 g/mol. It is a versatile chemical building block in organic synthesis, known for its potential biological activities such as antifungal and anti-inflammatory properties.

Uses

Used in Pharmaceutical Industry:
(+/-)-CIS-2-(4-BROMO-BENZOYL)-CYCLOPENTANECARBOXYLIC ACID METHYL ESTER is used as a key intermediate in the synthesis of various pharmaceuticals due to its versatile reactivity and functional groups.
Used in Agrochemical Industry:
(+/-)-CIS-2-(4-BROMO-BENZOYL)-CYCLOPENTANECARBOXYLIC ACID METHYL ESTER is used as a building block in the development of agrochemicals, contributing to the creation of effective and innovative products for agricultural applications.
Used in Drug Discovery and Development:
(+/-)-CIS-2-(4-BROMO-BENZOYL)-CYCLOPENTANECARBOXYLIC ACID METHYL ESTER is used as a target compound in drug discovery and development, owing to its potential biological activities such as antifungal and anti-inflammatory properties.

Upstream product

• 791594-13-3 trans-(1R,2R)-2-(4-bromobenzoyl)cyclopentanecarboxylic acid 
• 74-88-4 methyl iodide 
• 1019115-10-6 trans-(+/-)-2-(4-bromobenzoyl)cyclopentanecarboxylic acid 
• 1214270-80-0 2-bromo-6-(4-bromobenzoyl)cyclohexanone 
• 108-94-1 cyclohexanone 
• 1655-07-8 ethyl 2-oxocyclohexane carboxylate 
• 586-75-4 4-chlorobenzoyl chloride 
• 77-76-9 2,2-dimethoxy-propane 
• 108-86-1 bromobenzene 

Relevant articles and documents

Process development of a diacyl glycerolacyltransferase-1 inhibitor

A synthesis of a selective diacyl glycerolacyltransferase-1 (DGAT-1) inhibitor, 1, is described. The synthesis illustrates a diketone Favorskii reaction on 9 in place of the more common ketoester variant for generation of the dicarboxycyclopentane core, t

Validation of diacyl glycerolacyltransferase I as a novel target for the treatment of obesity and dyslipidemia using a potent and selective small molecule inhibitor

A highly potent and selective DGAT-1 inhibitor was identified and used in rodent models of obesity and postprandial chylomicron excursion to validate DGAT-1 inhibition as a novel approach for the treatment of metabolic diseases. Specifically, compound 4a conferred weight loss and a reduction in liver triglycerides when dosed chronically in DIO mice and depleted serum triglycerides following a lipid challenge in a dose-dependent manner, thus, reproducing major phenotypical characteristics of DGAT-1-/- mice.

Preparation and use of aryl alkyl acid derivatives for the treatment of obesity

This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases.