123437-73-0

Basic information

• Product Name: 3-benzyl-5-(4-methoxy-phenyl)-1-oxy-pyrazin-2-ylamine
• Synonyms: 3-benzyl-5-(4-methoxy-phenyl)-1-oxy-pyrazin-2-ylamine
• CAS NO: 123437-73-0
• Molecular Weight: 307.352
• Mol File: 123437-73-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-benzyl-5-(4-methoxy-phenyl)-1-oxy-pyrazin-2-ylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-benzyl-5-(4-methoxy-phenyl)-1-oxy-pyrazin-2-ylamine(123437-73-0)
• EPA Substance Registry System: 3-benzyl-5-(4-methoxy-phenyl)-1-oxy-pyrazin-2-ylamine(123437-73-0)

Safety Data

• Hazardous Substances Data: 123437-73-0(Hazardous Substances Data)

Upstream product

• 93554-83-7 α-aminophenylpropiononitrile hydrochloride 
• 151427-04-2 2-(p-methoxyphenyl)ethan-1,2-dion-1-oxime sodium salt 
• 1823-76-3 p-methoxy-isonitrosoacetophenone 
• 55379-75-4 2-amino-3-phenylpropanenitrile 

Downstream Products

• 55779-48-1 coelenterazine 
• 50909-86-9 2,8-dibenzyl-6-(4-hydroxyphenyl)imidazo[1,20-a]pyrazin-3(7H)one 
• 40040-83-3 3,7-dihydro-2-methyl-6-(p-hyroxyphenyl)-8-benzylimidazolo[1,2-a]pyrazin-3-one 
• 37156-84-6 4-(5-amino-6-benzyl-pyrazin-2-yl)-phenol 
• 137320-90-2 8-benzyl-6-hydroxyphenyl-2-(3-phenylpropyl)imidazo<1,2-a>pyrazin-3-one 
• 137320-89-9 8-benzyl-6-hydroxyphenyl-2-(2-phenylethyl)imidazo<1,2-a>pyrazin-3-one 
• 137320-88-8 8-benzyl-6-hydroxyphenyl-2-phenylimidazo<1,2-a>pyrazin-3-one 
• 40040-81-1 2-amino-3-benzyl-5-(4-methoxyphenyl)-pyrazine 
• 156686-47-4 2-tert-butyl-6-(p-methoxyphenyl)-8-benzyl-3,7-dihydroimidazo<1,2-a>pyrazin-3-one 

Relevant articles and documents

Low-temperature photooxygenation of coelenterate luciferin analog synthesis and proof of 1,2-dioxetanone as luminescence intermediate

Coelenterate luciferin analog having bulky tert-butyl group at the 2-position was suitable for studies on chemiluminescence under various conditions. Photooxygenation of the analog(s) at low temperature (-78°C) afforded luminous intermediates which were proved as peroxides by reduction with PPh3 with resultant loss of luminescence ability. In order to clarify these structures of accumulated luminous intermediates by means of 13C NMR, three 13C enriched analogs were synthesized at the 2, 3 and 5 positions of 3,7-dihydroimidazo[1,2-a]pyrazin-3-one skeleton in 99% enrichment with site-specificity. These 13C-enriched coelenterate luciferin analogs were photooxygenated at -78°C to form two peroxidic products as luminescent intermediates. Structures of these unstable intermediates were deduced by means of 13C NMR spectra at low temperature using substrates enriched at three sites by 13C. Photooxygenation in a mixture of CF3CD2OD and CD3OD as highly protic solvents afforded the dioxetanone and 2-hydroperoxide. These two peroxides emitted light independently at different temperatures either at 400 nm (neutral species) and/or 475 nm (anionic species) after diluting to 10-5 M in diglyme (DGM) containing acid or base.