1345413-26-4Relevant articles and documents
Synthetic method of ticagrelor midbody
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Paragraph 0015; 0016, (2017/10/13)
The invention provides a novel synthetic method of a ticagrelor midbody (1). The synthetic method comprises the following steps: enabling a compound (2) and a compound (3) to have asymmetric tertiary cyclization reaction under the catalysis of rhodium (a
Synthesis of nitrogen substituted cyclopropanes
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, (2013/05/22)
The invention is about a new synthetic pathway for the preparation of enantiomerically pure nitrogen substituted cyclopropanes, in particular the trans-cyclopropanamine (1), a key intermediate in the synthesis of Ticagrelor: The invention also relates to