1582787-69-6

Basic information

• Product Name: 4,5-dimethoxy-2-(trimethylsilyl)phenyl nonaflate
• Synonyms: 4,5-dimethoxy-2-(trimethylsilyl)phenyl nonaflate
• CAS NO: 1582787-69-6
• Molecular Weight: 508.434
• Mol File: 1582787-69-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4,5-dimethoxy-2-(trimethylsilyl)phenyl nonaflate(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-dimethoxy-2-(trimethylsilyl)phenyl nonaflate(1582787-69-6)
• EPA Substance Registry System: 4,5-dimethoxy-2-(trimethylsilyl)phenyl nonaflate(1582787-69-6)

Safety Data

• Hazardous Substances Data: 1582787-69-6(Hazardous Substances Data)

Upstream product

• 375-72-4 Nonafluorobutanesulfonyl fluoride 
• 1276113-16-6 4,5-dimethoxy-2-trimethylsilylphenol 

Downstream Products

• 398-62-9 4-fluoroveratrole 
• 2033-89-8 3,4-dimethoxyphenol 

Relevant articles and documents

Synthesis of fluorinated aromatic compounds by one-pot benzyne generation and nucleophilic fluorination

The fluorination of substituted benzenes using fluoride ions under mild reaction conditions has been one of the most important challenges for the synthesis of biologically active fluorinated aromatic compounds; however, only a few synthetically useful methods are known. In this paper, it is reported that the nucleophilic fluorination of benzynes, generated from either 2-(trialkylsilyl)phenyl nonafluorobutanesulfonates or 2-(trialkylsilyl)phenols, meets this challenge. In particular, the fluorination starting from 2-(trialkylsilyl)phenols for fabricating aryl fluorides involves three sequential reactions in one-pot: the nonaflylation of phenols, benzyne generation, and nucleophilic fluorination of the benzynes. The regioselectivities of these reactions are controlled by the substituents at the C3-position of the benzynes. CSIRO 2014.