17277-58-6

Basic information

• Product Name: METHYL (PHENYLTHIO)ACETATE
• Synonyms: METHYL (PHENYLTHIO)ACETATE;METHYL 2-(PHENYLTHIO)ACETATE;(PHENYLTHIO)ACETIC ACID METHYL ESTER;Methyl (phenylmercapto)acetate~(Phenylthio)acetic acid methyl ester;Methyl(phenythio)acetate;METHYL (PHENYLMERCAPTO)ACETATE;(Phenylthio)acetic acid methyl;2-(Phenylthio)acetic acid methyl
• CAS NO: 17277-58-6
• Molecular Formula: C₉H₁₀O₂S
• Molecular Weight: 182.24
• Mol File: 17277-58-6.mol
• Article Data: 62

Chemical Properties

• Boiling Point: 78-80 °C0.1 mm Hg
• Flash Point: >110°C
• Appearance: /
• Density: 1,17 g/cm3
• Vapor Pressure: 0.013mmHg at 25°C
• Refractive Index: n20/D 1.559
• BRN: 2047554
• CAS DataBase Reference: METHYL (PHENYLTHIO)ACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL (PHENYLTHIO)ACETATE(17277-58-6)
• EPA Substance Registry System: METHYL (PHENYLTHIO)ACETATE(17277-58-6)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 23-24/25-36/37/39-26
• WGK Germany: 3
• F: 13
• Hazardous Substances Data: 17277-58-6(Hazardous Substances Data)

Usage

General Description

Methyl (phenylthio)acetate is a chemical compound that is commonly used in cosmetic and fragrance products for its pleasant and fruity odor. It is considered a valuable ingredient in the production of perfumes, soaps, and lotions. The compound is characterized by its strong aroma, and can be found in natural substances such as fruit and flowers. Moreover, it is used as a flavoring agent in the food industry, particularly in the production of confectionery and baked goods. Despite its pleasant scent and flavor, individuals with sensitivity to fragrances may experience adverse reactions to products containing methyl (phenylthio)acetate. Therefore, caution should be exercised when using products that contain this chemical.

InChI:InChI=1/C9H10O2S/c1-11-9(10)7-12-8-5-3-2-4-6-8/h2-6H,7H2,1H3

Upstream product

• 930-69-8 sodium thiophenolate 
• 96-32-2 bromoacetic acid methyl ester 
• 67-56-1 methanol 
• 103-04-8 (phenylthio)acetic acid 
• 591-50-4 iodobenzene 
• 76310-90-2 Methoxycarbonylmethylthiotrimethylstannane 
• 14090-83-6 methyl 2-phenylsulfinylacetate 
• 72867-21-1 2-Phenylsulfanyl-malonic acid monomethyl ester 
• 96-34-4 methyl chloroacetate 
• 108-98-5 thiophenol 
• 139413-35-7 Trifluoro-methanesulfonate(2-acetyl-2-methoxycarbonyl-hexyl)-phenyl-trimethylsilanylmethyl-sulfonium; 
• 139373-36-7 Trifluoro-methanesulfonate(2,2-bis-methoxycarbonyl-propyl)-phenyl-trimethylsilanylmethyl-sulfonium; 
• 139373-21-0 Trifluoro-methanesulfonate(1-methoxycarbonyl-2-oxo-cyclopentylmethyl)-phenyl-trimethylsilanylmethyl-sulfonium; 
• 139373-23-2 Trifluoro-methanesulfonate(1-methoxycarbonyl-2-oxo-cyclohexylmethyl)-phenyl-trimethylsilanylmethyl-sulfonium; 

Downstream Products

• 13865-02-6 methoxyphenylsulfanylacetic acid methyl ester 
• 71841-09-3 (E)-methyl 6,10-dimethyl-2-(phenylthio)-5,9-undecadienoate 
• 63787-29-1 [4-(2-Chloro-acetyl)-phenylsulfanyl]-acetic acid methyl ester 
• 121671-51-0 (E)-(2R,3S)-3-Hydroxy-5-phenyl-2-phenylsulfanyl-pent-4-enoic acid methyl ester 
• 121671-51-0 (E)-(2R,3R)-3-Hydroxy-5-phenyl-2-phenylsulfanyl-pent-4-enoic acid methyl ester 
• 121671-43-0 (2R,3S)-3-Hydroxy-5-phenyl-2-phenylsulfanyl-pentanoic acid methyl ester 
• 121671-43-0 (2R,3R)-3-Hydroxy-5-phenyl-2-phenylsulfanyl-pentanoic acid methyl ester 
• 13307-60-3 2-methyl-1-(phenylthio)propan-2-ol 
• 84796-82-7 methyl 4-oxo-2-(phenylthio)pentanoate 
• 125442-81-1 (3-Oxo-cyclohexyl)-phenylsulfanyl-acetic acid methyl ester 
• 74143-92-3 (E)-methyl 5,9-dimethyl-2-(phenylthio)-4,8-decadienoate 
• 125442-80-0 (3-Oxo-cyclopentyl)-phenylsulfanyl-acetic acid methyl ester 
• 5042-53-5 1-(phenylsulfanyl)acetone 
• 100-68-5 methyl-phenyl-thioether 

Relevant articles and documents

Scalable electrochemical reduction of sulfoxides to sulfides

A scalable reduction of sulfoxides to sulfides in a sustainable way remains an unmet challenge. This report discloses an electrochemical reduction of sulfoxides on a large scale (>10 g) under mild reaction conditions. Sulfoxides are activated using a substoichiometric amount of the Lewis acid AlCl3, which could be regeneratedviaa combination of inexpensive aluminum anode with chloride anion. This deoxygenation process features a broad substrate scope, including acid-labile substrates and drug molecules.

Compound, preparation method thereof, medical intermediate and application thereof

The invention relates to the technical field of chemical synthesis, and particularly discloses a compound, a preparation method thereof, a medical intermediate and an application thereof, the compoundcomprises the following raw materials: thioether, bromide and a proper amount of organic solvent, and the molar weight ratio of thioether to bromide is 1: (2-8). According to the compound provided bythe invention, thioether, bromide and a proper amount of organic solvent are used as raw materials, and the thioether compound can be obtained without adopting a catalyst, so that the problems of metal residues and the like are fundamentally eliminated, the provided preparation method is simple to operate, the method is simple in process and high in yield, the thioether compound is prepared through thioether metathesis reaction, metal catalysis is not needed in the whole reaction, meanwhile, the reaction condition is mild, the substrate range is wide, the problem of metal pollution existing in an existing thioether compound synthesis method is solved, and the method has wide market prospects in the fields of organic synthesis, medicine synthesis and the like.

Rhodium-catalyzed Sommelet-Hauser type rearrangement of α-diazoimines: Synthesis of functionalized enamides

An efficient rhodium catalyzed Sommelet-Hauser type rearrangement of sulfur ylides derived from α-thioesters and N-sulfonyl-1,2,3-triazoles has been successfully accomplished for the synthesis of various functionalized enamides. The developed reaction involves the unprecedented [2,3]-sigmatropic rearrangement of sulfur ylides with the imine motif. Importantly, the method works well with various substituted α-thioesters/-amides/-ketones and substituted N-sulfonyl-1,2,3-triazoles and allows the synthesis of diverse enamide derivatives in good to excellent yields. The reaction was also successfully extended to the one-pot synthesis of enamides from terminal alkynes.