187831-22-7 Usage
Description
(+)-2-chloro-1-(4'-N-mesylaminophenyl)ethanol is a chiral chemical compound with the molecular formula C9H12ClNO3S. It features a chlorine atom, a hydroxyl group, and a mesylamine group attached to a phenyl ring. (+)-2-chloro-1-(4'-N-mesylaminophenyl)ethanol is commonly utilized in organic synthesis and medicinal chemistry as a chiral building block. Its unique structure and properties, along with the presence of a chiral center, make it a valuable compound for the preparation of enantiomerically pure products in various chemical reactions. Furthermore, it serves as an intermediate in the production of pharmaceuticals and agrochemicals, contributing to the development of new chemical processes and compounds.
Uses
Used in Organic Synthesis:
(+)-2-chloro-1-(4'-N-mesylaminophenyl)ethanol is used as a chiral building block for the synthesis of various organic compounds. Its unique structure allows for the creation of enantiomerically pure products, which are essential in many chemical reactions.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (+)-2-chloro-1-(4'-N-mesylaminophenyl)ethanol is employed as a key intermediate in the development of pharmaceuticals. Its chiral properties make it a crucial component in the synthesis of drugs with specific therapeutic effects.
Used in Pharmaceutical Production:
(+)-2-chloro-1-(4'-N-mesylaminophenyl)ethanol is utilized as an intermediate in the manufacturing process of various pharmaceuticals. Its presence in the synthesis contributes to the development of effective and targeted treatments.
Used in Agrochemical Production:
(+)-2-chloro-1-(4'-N-mesylaminophenyl)ethanol also finds application in the production of agrochemicals, where it serves as an intermediate in the synthesis of pesticides and other agricultural products. Its role in these processes helps to create more effective and targeted agrochemicals for crop protection and enhancement.
Used in the Development of New Chemical Processes:
(+)-2-chloro-1-(4'-N-mesylaminophenyl)ethanol is a valuable tool for researchers in the development of innovative chemical processes. Its unique structure and properties allow for the exploration of new reaction pathways and the creation of novel compounds with potential applications across various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 187831-22-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,7,8,3 and 1 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 187831-22:
(8*1)+(7*8)+(6*7)+(5*8)+(4*3)+(3*1)+(2*2)+(1*2)=167
167 % 10 = 7
So 187831-22-7 is a valid CAS Registry Number.
187831-22-7Relevant articles and documents
'Green' synthesis of important pharmaceutical building blocks: Enzymatic access to enantiomerically pure α-chloroalcohols
Zhu, Dunming,Mukherjee, Chandrani,Hua, Ling
, p. 3275 - 3278 (2007/10/03)
Thirty one recombinant ketoreductase enzymes were screened for the reduction of six α-chloroketones, the precursors of pharmaceutically valuable α-chloroalcohols. Several highly active and enantioselective ketoreductases were found and their applications
Chemoenzymatic synthesis of (S) and (R)-propranolol and sotalol employing one-pot lipase resolution protocol
Kamal, Ahmed,Sandbhor, Mahendra,Ali Shaik, Ahmad
, p. 4581 - 4583 (2007/10/03)
Synthesis of both enantiomers of biologically active propranolol and sotalol has been achieved in high optical purity by one-pot reduction of 3 and 7 followed by in situ lipase resolution of the respective chlorohydrins. Pseudomonas cepacia lipase immobilized on ceramic particles (PS-C) provided the chlorohydrin and acetate, which on nucleophilic substitution with isopropyl amine afforded the target amino alcohols in high enantioselectivity under mild reaction conditions.
Practical synthesis of optically active styrene oxides via reductive transformation of 2-chloroacetophenones with chiral rhodium catalysts
Hamada, Takayuki,Torii, Takayoshi,Izawa, Kunisuke,Noyori, Ryoji,Ikariya, Takao
, p. 4373 - 4376 (2007/10/03)
(equation presented) A practical method for the synthesis of optically active styrene oxides has been developed via formation of optically active 2-chloro-1-phenylethanols generated by reductive transformation of ring-substituted 2-chloroacetophenones. Th
