196597-77-0 Usage
Description
4,5-Dibromo-1,2,6,7-tetrahydro-8H-indeno[5,4-b]furan-8-one is a tricyclic indan derivative characterized as a white solid. It is known for its receptor agonist properties and has potential therapeutic applications.
Used in Pharmaceutical Industry:
4,5-Dibromo-1,2,6,7-tetrahydro-8H-indeno[5,4-b]furan-8-one is used as a receptor agonist for the development of therapeutic agents targeting sleep disorders. Its unique structure and properties allow it to modulate specific receptors, potentially leading to improved sleep patterns and treatment of related conditions.
Used in Chemical Research:
As a tricyclic indan derivative, 4,5-Dibromo-1,2,6,7-tetrahydro-8H-indeno[5,4-b]furan-8-one can be utilized in chemical research for the synthesis of novel compounds and the exploration of its chemical properties and potential applications beyond its current known uses.
Check Digit Verification of cas no
The CAS Registry Mumber 196597-77-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,6,5,9 and 7 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 196597-77:
(8*1)+(7*9)+(6*6)+(5*5)+(4*9)+(3*7)+(2*7)+(1*7)=210
210 % 10 = 0
So 196597-77-0 is a valid CAS Registry Number.
InChI:InChI=1/C11H8Br2O2/c12-9-5-1-2-7(14)8(5)6-3-4-15-11(6)10(9)13/h1-4H2
196597-77-0Relevant articles and documents
Preparation method of ramelteon impurity
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Paragraph 0029-0031; 0043-0045, (2020/02/29)
The invention relates to a preparation method of a ramelteon impurity, and belongs to the technical field of chemical synthesis. The preparation method comprises the following steps: (1) reacting a compound I with oxalyl chloride to generate an acyl chloride compound, adding aluminum trichloride, and carrying out a Friedel-Crafts reaction to generate a compound II; and (2) directionally generatinga compound III from the compound II under the action of Raney cobalt and hydrazine hydrate. The preparation method provides a novel and safe reduction condition for direct synthesis of the monosubstituted impurity, and the product does can be directly used as an impurity reference substance without purification, and also can be directly subjected to a subsequent impurity transfer experiment.
PROCESS FOR PREPARATION OF (S)-N-[2-(1,6,7,8-TETRAHYDRO-2H-INDENO[5,4-B]FURAN-8-YL)ETHYL] PROPIONAMIDE AND NOVEL INTERMEDIATES THEREOF
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Page/Page column 30, (2010/04/28)
Disclosed herein process for preparation of (S)-Ramelteon and intermediates thereof.
PROCESS FOR THE SYNTHESIS OF RAMELTEON AND ITS INTERMEDIATES
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, (2009/01/24)
The present invention provides processes and intermediates for the synthesis of ramelteon.
