19739-60-7

Basic information

• Product Name: Cbz-leucylglycyl hydrazide
• CAS NO: 19739-60-7
• Molecular Weight: 336.391
• Mol File: 19739-60-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Cbz-leucylglycyl hydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: Cbz-leucylglycyl hydrazide(19739-60-7)
• EPA Substance Registry System: Cbz-leucylglycyl hydrazide(19739-60-7)

Safety Data

• Hazardous Substances Data: 19739-60-7(Hazardous Substances Data)

Upstream product

• 2867-06-3 Benzyloxycarbonylleucyl-glycine ethyl ester 
• 87024-12-2 (S)-1-(2'-benzyloxycarbonylamino-4'-methylpentanoyl)-3,5-dimethylpyrazole 
• 4703-53-1 N-benzyloxycarbonyl-L-leucine hydrazide 
• 58889-73-9 (S)-N-benzyloxycarbonyl-leucine ethyl ester 
• 2018-66-8 Z-Leu-OH 
• 5084-98-0 methyl N-benzyloxycarbonyl-L-leucylglicynate 

Downstream Products

• 76314-54-0 Z-Leu-Gly-Cys(Bzl)-Gln-Ile-Cys(Bzl)-Leu-NHNH₂ 
• 76314-53-9 Z-Leu-Gly-Cys(Bzl)-Gln-Ile-Cys(Bzl)-Leu-OMe 
• 76314-77-7 Z-Leu-Gly-Cys(Bzl)-Gln-OH 

Relevant articles and documents

New system for peptide synthesis using N-acylpyrazoles

New system of peptide synthesis was described. The extension of one amino acid unit on the peptide chain was constituted from only 2 reaction steps, the conversion from esters to the corresponding N-acylpyrazoles and the subsequent aminolysis with amino esters. This new system was distinctive from the conventional peptide synthesis, which was consisted of 3 steps of the deprotection, the activation and the condensation. Moreover, the key intermediate N-acylpyrazoles exhibited the excellent properties of high sensitivity and separability for the chiral column on HPLC using the UV detector.