19810-31-2 Usage
Description
Benzyloxyacetyl chloride is a colorless to yellow liquid that serves as a versatile reagent in the field of organic chemistry. It is primarily utilized for the construction of substituted 2-azetidinones, which can be further elaborated into annulated β-lactams. Its unique chemical properties make it a valuable component in asymmetric synthesis processes.
Uses
1. Used in Pharmaceutical Industry:
Benzyloxyacetyl chloride is used as a key reagent for the asymmetric synthesis of β-lactams. These β-lactams are essential components in the development of various antibiotics, such as fluoroquinolones, which are widely used for treating respiratory tract infections.
2. Used in Organic Synthesis:
Benzyloxyacetyl chloride is employed as a commonly used reagent in the preparation of complex organic molecules, such as (S)-3-(methylamino)-3-((R)-pyrrolidin-3-yl)propanenitrile. Benzyloxyacetyl chloride serves as a key intermediate in the synthesis of fluoroquinolone antibiotics, which are crucial for combating bacterial infections.
3. Used in the Synthesis of Chiral Compounds:
Benzyloxyacetyl chloride is used as a reagent for the asymmetric synthesis of non-racemic helicene, a chiral compound with potential applications in various fields, including pharmaceuticals and materials science.
4. Used in the Synthesis of β-lactams:
Benzyloxyacetyl chloride is also utilized in the preparation of β-lactams, which are important structural elements in various pharmaceutical compounds, particularly antibiotics. The asymmetric synthesis of these β-lactams using benzyloxyacetyl chloride allows for the creation of enantiomerically pure products, which are essential for the development of effective and safe medications.
Check Digit Verification of cas no
The CAS Registry Mumber 19810-31-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,8,1 and 0 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 19810-31:
(7*1)+(6*9)+(5*8)+(4*1)+(3*0)+(2*3)+(1*1)=112
112 % 10 = 2
So 19810-31-2 is a valid CAS Registry Number.
InChI:InChI=1/C9H9ClO2/c10-9(11)7-12-6-8-4-2-1-3-5-8/h1-5H,6-7H2
19810-31-2Relevant articles and documents
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Fischer,Gohlke
, p. 1130,1138 (1933)
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COMPOUNDS
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Page/Page column 52; 76, (2021/12/08)
The invention relates to novel compounds for use as inhibitors of NLRP3 inflammasone production, wherein such compounds are as defined by compounds of formula (I) and wherein the integers R1, R2 and R3 are defined in the description, and where the compounds may be useful as medicaments, for instance for use in the treatment of a disease or disorder that is associated with NLRP3 inflammasome activity.
CYCLOBUTYL PYRAZOLOPYRIMIDINE PDE9 INHIBITORS
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Page/Page column 43; 44, (2020/07/07)
The present invention is directed to cyclobutyl pyrazolopyrimidine compounds which may be useful as therapeutic agents for the treatment of disorders associated with phosphodiesterase 9 (PDE9). The present invention also relates to the use of such compounds for treating cardiovascular and cerebrovascular diseases, such as hypertension, chronic kidney disease and heart failure, and neurological and psychiatric disorders, such as schizophrenia, psychosis or Huntington's disease, and those associated with striatal hypofunction or basal ganglia dysfunction.
