2085-90-7

Basic information

• Product Name: 1,4-Diphenylbutane-1,4-diol
• Synonyms: 1,4-Diphenyl-1,4-butanediol;1,4-Diphenylbutane-1,4-diol
• CAS NO: 2085-90-7
• Molecular Formula: C₁₆H₁₈O₂
• Molecular Weight: 242.31
• Mol File: 2085-90-7.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 418.5°C at 760 mmHg
• Flash Point: 199°C
• Appearance: /
• Density: 1.14g/cm³
• Vapor Pressure: 9.4E-08mmHg at 25°C
• Refractive Index: 1.599
• CAS DataBase Reference: 1,4-Diphenylbutane-1,4-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Diphenylbutane-1,4-diol(2085-90-7)
• EPA Substance Registry System: 1,4-Diphenylbutane-1,4-diol(2085-90-7)

Safety Data

• Hazardous Substances Data: 2085-90-7(Hazardous Substances Data)

Usage

Derivative

Butanediol

Structure

Central butane chain with phenyl groups attached to the 1 and 4 positions

Common use

Synthesis of various organic compounds

Applications

Pharmaceutical and cosmetic industries

Potential use

Building block for novel drugs and materials development

Unique properties

Chemical structure and properties

Research interest

Antioxidant and anti-inflammatory properties

Subject of interest

Medical research

InChI:InChI=1/C16H18O2/c17-15(13-7-3-1-4-8-13)11-12-16(18)14-9-5-2-6-10-14/h1-10,15-18H,11-12H2

Upstream product

• 959-28-4 1,4-diphenylbut-2-ene-1,4-dione 
• 495-71-6 phenacylacetophenone 
• 100-42-5 styrene 
• 70769-82-3 1-Phenyl-3-phenylsulfanylpropanol 
• 100-52-7 benzaldehyde 
• 64-17-5 ethanol 
• 861541-57-3 5-bromo-4-chloro-2,4-diphenyl-tetrahydro-furan-3-ol 
• 693-03-8 n-butyl magnesium bromide 
• 927-77-5 n-propylmagnesium bromide 
• 107-06-2 1,2-dichloro-ethane 
• 96-09-3 styrene oxide 
• 19513-91-8 (Z)-4-bromo-2,3-epoxy-1,3-diphenyl-1-butanone 
• 4482-17-1 1,4-diphenyl-but-2-yne-1,4-diol 
• 4187-87-5 1-Phenyl-2-propyn-1-ol 

Downstream Products

• 6165-44-2 1,4-dicyclohexyl-butane 
• 3617-23-0 meso-1,4-dichloro-1,4-diphenylbutane 
• 50637-09-7 cis-2,5-diphenyl-tetrahydrofuran 
• 50637-09-7 2,5-diphenyltetrahydrofuran 
• 955-83-9 2,5-diphenylfuran 
• 495-71-6 phenacylacetophenone 
• 886-65-7 trans,trans-1,4-Diphenyl-1,3-butadiene 
• 82631-96-7 (+/-)-1,4-diphenyltetramethylene bismethanesulphonate 
• 16844-20-5 1,4-dibromo-1,4-diphenyl-butane 
• 82631-96-7 1,4-diphenyl-1,4-butanediol bis(methanesulfonic acid ester) 
• 51751-09-8 2,5-diphenyltetrahydrofuran 
• 929721-56-2 (meso)-2,5-diphenylcyclopentane-1,1-dimethanol 
• 929721-54-0 (meso)-2,5-diphenylcyclopentane-1,1-dicarboxylic acid diethyl ester 
• 295328-86-8 (2S,5S)-N-allyl-2,5-diphenylpyrrolidine 

Relevant articles and documents

Selective mono addition of aryllithiums to dialdehydes by micromixing

Micromixing enables highly selective mono addition of aryllithiums to dialdehydes. Because the unchanged formyl group in the products can be used for further transformations, the present approach serves as a powerful method for protecting-group-free synthesis.

Arene-promoted lithiation of 1,n-dihaloalkanes (n=2-6): a comparative study

The reaction of 1,n-dichloroalkanes 3a (n=2-6) with an excess of lithium powder and a catalytic amount of 4,4′-di-tert-butylbiphenyl (DTBB; 2.5 mol %) in the presence of different carbonyl compounds [ButCHO, PhCHO, Et2CO, (CH2/

Stereoselective Synthesis of anti-1,4-Diols by a BH3· THF-Mediated Rearrangement of 1,2-Disubstituted Cyclobutenes

A new stereoselective rearrangement of cyclobutylboranes, obtained by the hydroboration of 1,2-disubstituted cyclobutenes, provides anti-1,4-diols with good-to-excellent diastereoselectivity. The mechanism of the rearrangement is discussed based on theoretical calculations.