220353-16-2Relevant articles and documents
2,6-difluorophenol as a bioisostere of a carboxylic acid: Bioisosteric analogues of γ-aminobutyric acid
Qiu, Jian,Stevenson, Scott H.,O'Beirne, Michael J.,Silverman, Richard B.
, p. 329 - 332 (1999)
3-(Aminomethyl)-2,6-difluorophenol (6) and 4-(aminomethyl)-2,6- difluorophenol (7) were synthesized in eight and four steps, respectively, starting from 2,6-difluorophenol, to test the potential of the 2,6- difluorophenol moiety to act as a lipophilic bio