220353-18-4 Usage
Type of compound
Halogenated aromatic compound
Structure
Benzene ring substituted with two fluorine atoms, one iodine atom, and one methoxy group
Applications
a. Organic synthesis
b. Pharmaceutical research
c. Building block for the synthesis of various organic compounds
Chemical properties
a. Strong electron-withdrawing abilities
b. Reactant in the synthesis of more complex fluorine-containing compounds
Safety precautions
Handle with care, as it may be hazardous if not used properly.
Check Digit Verification of cas no
The CAS Registry Mumber 220353-18-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,0,3,5 and 3 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 220353-18:
(8*2)+(7*2)+(6*0)+(5*3)+(4*5)+(3*3)+(2*1)+(1*8)=84
84 % 10 = 4
So 220353-18-4 is a valid CAS Registry Number.
220353-18-4Relevant articles and documents
2,6-difluorophenol as a bioisostere of a carboxylic acid: Bioisosteric analogues of γ-aminobutyric acid
Qiu, Jian,Stevenson, Scott H.,O'Beirne, Michael J.,Silverman, Richard B.
, p. 329 - 332 (2007/10/03)
3-(Aminomethyl)-2,6-difluorophenol (6) and 4-(aminomethyl)-2,6- difluorophenol (7) were synthesized in eight and four steps, respectively, starting from 2,6-difluorophenol, to test the potential of the 2,6- difluorophenol moiety to act as a lipophilic bio
