275801-69-9

Basic information

• Product Name: L-Isoleucine, N-[3-(4-hydroxyphenyl)-1-oxopropyl]-
• CAS NO: 275801-69-9
• Molecular Formula: C15H21NO4
• Molecular Weight: 279.336
• Mol File: 275801-69-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: L-Isoleucine, N-[3-(4-hydroxyphenyl)-1-oxopropyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: L-Isoleucine, N-[3-(4-hydroxyphenyl)-1-oxopropyl]-(275801-69-9)
• EPA Substance Registry System: L-Isoleucine, N-[3-(4-hydroxyphenyl)-1-oxopropyl]-(275801-69-9)

Safety Data

• Hazardous Substances Data: 275801-69-9(Hazardous Substances Data)

Upstream product

• 501-97-3 4-hydroxyphenylpropionic acid 
• 34071-95-9 N-succinimidyl-3-(p-hydroxyphenyl)propionate 
• 73-32-5 L-isoleucine 

Downstream Products

• 502761-26-4 RA-1003 
• 663923-69-1 1-(tert-butyloxycarbonylamino)-4-{N-[3-(4-hydroxyphenyl)propionyl]-L-isoleucyl-glycylamino}butane 
• 663923-68-0 N-[3-(4-hydroxyphenyl)propionyl]-L-isoleucyl-glycine 
• 658053-32-8 N-[3-(4-hydroxyphenyl)propionyl]-L-isoleucyl-L-proline 2-[4-(tert-butyloxycarbonyl)piperazin-1-yl]ethyl ester 
• 502761-25-3 1-tert-butoxycarbonylamino-4-{N-[3-(4-hydroxyphenyl)propionyl]-L-isoleucyl-L-prolylamino}butane 
• 658053-31-7 N-[3-(4-hydroxyphenyl)propionyl]-L-isoleucyl-L-proline 
• 502761-23-1 N-[3-(4-hydroxyphenyl)propionyl]-L-isoleucyl-L-proline methyl ester 

Relevant articles and documents

Synthesis of a cyanopeptide-analogue with trypsin activating properties

An efficient synthesis of a peptidic analogue of cyanobacterial metabolites with proposed serine protease inhibitory activity has been developed. Surprisingly, one trypsin activating compound was obtained. (C) 2000 Elsevier Science Ltd. All rights reserved.

Cyanopeptide analogues: New lead structures for the design and synthesis of new thrombin inhibitors

This contribution deals with the structure-based design and syntheses of the new serine protease inhibitors RA-1001 and RA-1002, which are analogues of the blue-green algae derived cyanopeptide aeruginosin 98-B. Both compounds inhibit thrombin with Ki values of 5.6 μM and 8.7 μM, respectively.