324-80-1Relevant articles and documents
CO2/Photoredox-Cocatalyzed Tandem Oxidative Cyclization of α-Bromo Ketones and Amines to Construct Substituted Oxazoles
Zhang, Xiaowei,He, Yonghui,Li, Jing,Wang, Rui,Gu, Lijun,Li, Ganpeng
, p. 8225 - 8231 (2019/06/17)
CO2/photoredox-cocatalyzed tandem oxidative cyclization of α-bromo ketones and amines for the preparation of substituted oxazoles has been achieved. The avoidance of using both transition-metal catalysts and peroxides makes this method more sustainable and renewable.
Metal-free iodine(iii)-promoted synthesis of 2,5-diaryloxazoles
Yang, Xueying,Guo, Xin,Qin, Mingda,Yuan, Xinglong,Jing, Huanwang,Chen, Baohua
supporting information, p. 3104 - 3108 (2018/05/22)
A nonmetal-catalyzed oxidative cyclization to achieve 2,5-disubstituted oxazoles from inexpensive and readily available substituted chalcone, (diacetoxyiodo)benzene (PIDA) and ammonium acetate (NH4OAc) at room temperature is described. The reaction forms a variety of 2,5-diaryloxazoles in good to excellent yields with broad substrate scope under mild conditions without the requirement of ligands and additional bases.
Synthesis of Substituted Oxazoles by Visible-Light Photocatalysis
Chatterjee, Tanmay,Cho, Ji Young,Cho, Eun Jin
, p. 6995 - 7000 (2016/08/30)
A simple and practical method for the synthesis of substituted oxazoles has been developed using readily available α-bromoketones and benzylamines by visible-light photocatalysis at room temperature. The process, which requires 1 mol % of [Ru(bpy)3]Cl2 photocatalyst with K3PO4 and CCl3Br, is effective for accessing a variety of valuable oxazole compounds. The synthetic utility of our protocol was also demonstrated by preparing a natural product, texaline.