329185-63-9Relevant articles and documents
Regioselective ortho-directed metalation and electrophilic substitution of indole- and indoline-5-(N-phenyl)carboxamides
Rousseau, Jean-Fran?ois,Dodd, Robert H.
, p. 2289 - 2304 (2007/10/03)
Treatment of 1-(N,N-dimethylsulfamoyl)-1H-indole-5-(N-phenyl) carboxamide (1) with s-butyllithium at -80°C in THF followed by addition of an electrophile gave exclusively the product of C-2 substitution. A second metalation-substitution cycle on this prod